Abstract:
:Early left-hemispheric brain lesions may lead to a reorganization of language into the right hemisphere. Language functions are consecutively spared, but visuospatial functions show slight deficits. Cortical 'crowding' of the right hemisphere has been suggested as an explanation for this effect, but no direct evidence has as yet been put forward. We examined six patients with early left-hemispheric brain lesions and subsequent right-hemispheric language organization with functional magnetic resonance imaging and compared their activation patterns in a verbal and two nonverbal tasks with the patterns of six controls. In the patient group, nonverbal functions were reorganized neither interhemispherically nor intrahemispherically. Instead, verbal and nonverbal functions were mediated by a common right-hemispheric network. This argues in favour of the 'crowding hypothesis'.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Lidzba K,Staudt M,Wilke M,Grodd W,Krägeloh-Mann Idoi
10.1097/01.wnr.0000221841.12632.d6subject
Has Abstractpub_date
2006-06-26 00:00:00pages
929-33issue
9eissn
0959-4965issn
1473-558Xpii
00001756-200606260-00016journal_volume
17pub_type
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