Lesion-induced right-hemispheric language and organization of nonverbal functions.

Abstract:

:Early left-hemispheric brain lesions may lead to a reorganization of language into the right hemisphere. Language functions are consecutively spared, but visuospatial functions show slight deficits. Cortical 'crowding' of the right hemisphere has been suggested as an explanation for this effect, but no direct evidence has as yet been put forward. We examined six patients with early left-hemispheric brain lesions and subsequent right-hemispheric language organization with functional magnetic resonance imaging and compared their activation patterns in a verbal and two nonverbal tasks with the patterns of six controls. In the patient group, nonverbal functions were reorganized neither interhemispherically nor intrahemispherically. Instead, verbal and nonverbal functions were mediated by a common right-hemispheric network. This argues in favour of the 'crowding hypothesis'.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Lidzba K,Staudt M,Wilke M,Grodd W,Krägeloh-Mann I

doi

10.1097/01.wnr.0000221841.12632.d6

subject

Has Abstract

pub_date

2006-06-26 00:00:00

pages

929-33

issue

9

eissn

0959-4965

issn

1473-558X

pii

00001756-200606260-00016

journal_volume

17

pub_type

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