Between-site reliability of startle prepulse inhibition across two early psychosis consortia.

abstract：:Bone marrow mononuclear cells (BMMCs) are known to enhance recovery from ischemic insults by secreting angiogenic factors and inducing the expression of angiogenic factors from host tissues. Therefore, the transplantation of BMMCs is considered a potential approach to promoting the repair of ischemic damaged organs. H...

journal_title：Neuroreport

authors： Takagi T,Yoshida T,Okada M,Hata R,Hato N,Gyo K,Hakuba N

更新日期：2014-08-06 00:00:00

abstract：:Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's disease. However, the role of SIRT2 in oxidative stress-induced cell death has remained unclear. In this study, we investigated the roles of SIRT2 in...

journal_title：Neuroreport

authors： Nie H,Hong Y,Lu X,Zhang J,Chen H,Li Y,Ma Y,Ying W

更新日期：2014-08-06 00:00:00

abstract：:Single-pulse unilateral electrical stimulation of either the amygdala or the inferior colliculus elicited startle-like responses in chloral hydrate anesthetized rats. EMG responses to intracranial stimulation were recorded from the anterior biceps femoris muscles. The EMG responses were generally enhanced following un...

journal_title：Neuroreport

authors： Lin C,Wan X,Zhao W,Ma C,Ma C,Gao Y,Zhou Y,Yeomans JS,Li L

更新日期：2002-10-07 00:00:00

abstract：:The present study used scores from Seligman's Attribution Style Questionnaire and [15O] water positron emission tomographic measurements of regional cerebral blood flow (rCBF) to investigate the relation between individual differences in dispositional pessimism and amygdala activity. During scanning 13 healthy non-sna...

journal_title：Neuroreport

authors： Fischer H,Tillfors M,Furmark T,Fredrikson M

更新日期：2001-06-13 00:00:00

abstract：:CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

journal_title：Neuroreport

authors： Bilsland JG,Harper SJ

更新日期：2003-05-23 00:00:00

abstract：:Papaverine is a non-specific vasodilatory drug, which was found to unexpectedly cause opening of the blood-brain barrier (BBB). We studied the expression of two endothelial cell related markers, endothelial barrier antigen (EBA) as a marker of BBB intactness, and matrix metalloproteinase-9 (MMP-9), an extracellular ma...

journal_title：Neuroreport

authors： Bhattacharjee AK,Kondoh T,Ikeda M,Kohmura E

更新日期：2002-12-03 00:00:00

abstract：:We measured regional cerebral blood flow using positron emission tomography in seven normal volunteers during discrimination tasks for visual patterns. For the 'attention to right or left' tasks, the subjects were instructed to press a key when sample and test stimuli presented in the right or left visual fields, resp...

journal_title：Neuroreport

authors： Kawashima R,Satoh K,Goto R,Inoue K,Itoh M,Fukuda H

更新日期：1998-05-11 00:00:00

abstract：:Changes in nitric oxide (NO) concentration and cerebral blood flow (CBF) in the parietal cortex during hypercapnoea were investigated in anaesthetized rats, using a NO-selective electrode and laser Doppler flowmetry. When hypercapnoea was induced by inhalation of 5% CO2 for 10 min, both the NO concentration and CBF in...

journal_title：Neuroreport

authors： Harada M,Fuse A,Tanaka Y

更新日期：1997-03-03 00:00:00

abstract：:In order to accomplish desired movements, the nervous system must specify the movement dynamics: it must provide a signal that compensates for the mechanical constraints encountered during movement. Here we tested whether the population activity of Purkinje cells in the cerebellum specifies the dynamics for pursuit ey...

journal_title：Neuroreport

authors： Krauzlis RJ

更新日期：2000-04-07 00:00:00

abstract：:Brief tetanic stimulation of parallel fibres can evoke a slow excitatory postsynaptic potential (EPSP) in cerebellar Purkinje cells that is mediated by metabotropic glutamate receptors (mGluRs). It is likely that the receptor subtype involved is mGluR1, which couples to the production of diacylglycerol and inositol-1,...

journal_title：Neuroreport

authors： Batchelor AM,Vranesic I,Del Principe F,Garthwaite J,Knöpfel T

更新日期：1996-08-12 00:00:00

abstract：:The aim of the present study was to examine the effects of nicotinamide, a co-factor in the electron transport chain, on the relationship between methamphetamine (MA)-induced striatal dopamine (DA) depletion and energy metabolism change. Four injections of MA (10 mg/kg, i.p.) at 2 h intervals resulted in decreases of ...

journal_title：Neuroreport

authors： Huang NK,Wan FJ,Tseng CJ,Tung CS

更新日期：1997-05-27 00:00:00

abstract：:The tonic discharge of rat medial vestibular nucleus (MVN) neurons, and their responsiveness to GABA receptor agonists were investigated in slices prepared from aged rats (24 months old). Aged MVN neurons showed regular spontaneous activity similar to that seen in slices from young adults. However the inhibitory effec...

journal_title：Neuroreport

authors： Him A,Johnston AR,Yau JL,Seckl J,Dutia MB

更新日期：2001-12-21 00:00:00

abstract：:Axons from central neurons can regenerate into the tissue matrix formed within a silicone tube capped with two pieces of peripheral nerve, one of which had been sutured to a lesion in the spinal cord. Such axons can grow through a transversely positioned microchip in the tube. These observations suggest that it is fea...

journal_title：Neuroreport

authors： Lundborg G,Drott J,Wallman L,Reimer M,Kanje M

更新日期：1998-03-30 00:00:00

abstract：:The role of spinal NMDA receptors in mechanical nociceptive processing was assessed in sheep. Intrathecal NMDA (2 nmol-1 micromol) produced a significant reduction in mechanical withdrawal thresholds. This effect was attenuated by pretreatment with the NMDA receptor antagonist MK801 (100 nmol), the cyclooxygenase-2 (C...

journal_title：Neuroreport

authors： Dolan S,Nolan AM

更新日期：1999-02-25 00:00:00

abstract：:The aim of this study was to investigate the changes in insular cortex metabolites and the correlation with clinical manifestations in patients with obstructive sleep apnea syndrome (OSA). Lateral insular metabolite levels were measured and relevant ratios were calculated in OSA patients and healthy individuals, inclu...

journal_title：Neuroreport

authors： Kang J,Tian Z,Li M

更新日期：2018-08-15 00:00:00

abstract：:Previous studies have established a role for N-methyl-D-aspartate receptor (NMDAR) containing the GluN2B subunit in efficient learning behavior on a variety of tasks. Recent findings have suggested that NMDAR on GABAergic interneurons may underlie the modulation of striatal function necessary to balance efficient acti...

journal_title：Neuroreport

authors： Brigman JL,Daut RA,Saksida L,Bussey TJ,Nakazawa K,Holmes A

更新日期：2015-06-17 00:00:00

abstract：:Insulin-like growth factor (IGF)-I is essential for cerebellar granule neuron survival and a decline in IGF-I is implicated in various age-dependent processes. Here we show that IGF-I mRNA levels are decreased in the cerebellum of old rats compared with young rats and this was associated with increased cell death and ...

journal_title：Neuroreport

authors： Pañeda C,Arroba AI,Frago LM,Holm AM,Rømer J,Argente J,Chowen JA

更新日期：2003-08-26 00:00:00

abstract：:Neurons of the vertebrate retina possess receptors for many neurotransmitters. Particularly interesting is a new type of GABA receptor (GABA rho) that, in contrast to GABAA and GABAB receptors, shows very little desensitization, is not blocked by bicuculline, and is not activated by baclofen. Homomeric human GABA rho ...

journal_title：Neuroreport

authors： Calvo DJ,Miledi R

更新日期：1995-05-30 00:00:00

abstract：:Addition of the beta-hydroxy-beta-methylglutaryl-CoA (HmG-CoA) reductase inhibitor lovastatin to human HEK cells transfected with the amyloid precursor protein (APP) reduces intracellular cholesterol/protein ratios by 50%, and markedly inhibits beta-secretase cleavage of newly-synthesized APP. Exogenous water-solubili...

journal_title：Neuroreport

authors： Frears ER,Stephens DJ,Walters CE,Davies H,Austen BM

更新日期：1999-06-03 00:00:00

abstract：:Bilabial, alveolar and velar sounds are produced at different locations around the oral cavity. fMRI was used to localize cortical representation of articulation in seven healthy subjects during repetitive lip and vertical tongue movements as well as repetitive articulation of /pa/ (bilabial), /ta/ (alveolar), /ka/ (v...

journal_title：Neuroreport

authors： Lotze M,Seggewies G,Erb M,Grodd W,Birbaumer N

更新日期：2000-09-11 00:00:00

abstract：:The neuroprotective effect of docosahexaenoic acid (DHA) on the glutamate-induced cytotoxicity in rat hippocampal cultures was investigated in the present study. DHA at 5-50 microg/ml successfully protected neurons against the cytotoxicity, markedly increased the cell viability, inhibited both nitric oxide (NO) produc...

journal_title：Neuroreport

authors： Wang X,Zhao X,Mao ZY,Wang XM,Liu ZL

更新日期：2003-12-19 00:00:00

abstract：:Where and how the cortical areas are activated when a person receives the result of hypothesis testing is still unclear. By using a category induction task, this study provided participants with various batteries and asked them to learn which kind of batteries were charged. After learning, they were required to give a...

journal_title：Neuroreport

authors： Li F,Cao B,Lei Y,Li H

更新日期：2009-01-28 00:00:00

abstract：:Lesions involving the dorsolateral prefrontal lobes may produce deficits on conceptual reasoning (CR) tasks in humans. Such deficits can also occur with subcortical lesions involving the basal ganglia, thalamus, or cerebellum, suggesting a common, yet widespread, neural network supporting this executive function. Here...

journal_title：Neuroreport

authors： Rao SM,Bobholz JA,Hammeke TA,Rosen AC,Woodley SJ,Cunningham JM,Cox RW,Stein EA,Binder JR

更新日期：1997-05-27 00:00:00

abstract：:SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identifie...

journal_title：Neuroreport

authors： Fang ZX,Hong SQ,Li TS,Wang J,Xie LL,Han W,Jiang L

更新日期：2019-06-12 00:00:00

abstract：:Sound localization can be affected by vision; in the ventriloquism effect, sounds that are hard to localize within hearing become mislocalized toward the location of concurrent visual events. Here we tested whether spatial attention is drawn to the illusory location of a ventriloquized sound. The study exploited our p...

journal_title：Neuroreport

authors： Spence C,Driver J

更新日期：2000-06-26 00:00:00

abstract：:In order to ascertain whether disturbances of neurogenesis occur in chronic neurodegenerative disorders, we assessed hippocampal cell proliferation in the R6/1 transgenic mouse model of Huntington's disease (HD). Using BrdU labelling for dividing cells at two different time points (5 and 20 weeks) in transgenic and wi...

journal_title：Neuroreport

authors： Lazic SE,Grote H,Armstrong RJ,Blakemore C,Hannan AJ,van Dellen A,Barker RA

更新日期：2004-04-09 00:00:00

abstract：:Blood oxygen level dependent MRI was used to test whether cocaine-stimulated mesolimbic activity varied with sexual receptivity. Rats were randomly screened for lordotic responses and were then imaged for their responses to centrally administered cocaine. We observed that female rats expressing no lordosis showed a gr...

journal_title：Neuroreport

authors： Febo M,Segarra AC,Stolberg TL,Ferris CF

更新日期：2011-01-05 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...

journal_title：Neuroreport

authors： Kyriakareli A,Cousins S,Pettorossi VE,Bronstein AM

更新日期：2013-10-02 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF), leukaemia inhibitory factor (LIF), oncostatin M (OSM), interleukin-6 (IL-6), and interleukin-11 (IL-11) are structurally and functionally related cytokines. We compared their survival-promoting activities on embryonic chick and newborn rat dorsal root ganglion (DRG) neurones. Human ...

journal_title：Neuroreport

authors： Simon R,Thier M,Krüttgen A,Rose-John S,Weiergräber O,Heinrich PC,Schröder JM,Weis J

更新日期：1995-12-29 00:00:00

abstract：:Absence seizures are known to originate from disruptions within the corticothalamocortical network; however, the precise underlying cellular and molecular mechanisms that induce hypersynchronicity and hyperexcitability are debated and likely to be complex and multifactorial. Recent studies implicate impaired thalamic ...

journal_title：Neuroreport

authors： Seo S,Leitch B

更新日期：2017-12-13 00:00:00