Changes in insular cortex metabolites in patients with obstructive sleep apnea syndrome.

abstract：:There is no unifying hypothesis to account for the anatomical distribution of neuropathology, the involvement of beta-amyloid precursor protein (beta APP) and the role of increasing age in triggering the Alzheimer disease process. We report here that layer II pre-alpha neurones in transentorhinal and entorhinal cortex...

journal_title：Neuroreport

authors： Roberts GW,Nash M,Ince PG,Royston MC,Gentleman SM

更新日期：1993-01-01 00:00:00

abstract：:Latexin is a novel 29 kDa protein which is expressed in a subpopulation of neurones in the lateral cerebral cortex of adult rats. Here, we report the distribution of immunohistochemically detectable latexin in the rat brain during early phases of development. Latexin was first detected at embryonic day 11 (E11) along ...

journal_title：Neuroreport

authors： Takiguchi-Hayashi K,Arimatsu Y

更新日期：1995-01-26 00:00:00

abstract：:To observe sequential stages in tactile pattern discrimination and their modification with and without attention, we used whole-head anatomically constrained magnetoencephalography to spatiotemporally map brain responses. Eight, normal, right-handed participants discriminated between two patterns presented on the palm...

journal_title：Neuroreport

authors： Reed CL,Hagler DJ Jr,Marinkovic K,Dale A,Halgren E

更新日期：2009-07-01 00:00:00

abstract：:In situ hybridization has demonstrated mRNA for olfactory receptors (OR) in the axon terminals of olfactory receptor neurons. Neurons that express the same OR appear to send their axons to two stereotyped glomeruli in the olfactory bulb (OB). Based on these observations, we tested the feasibility of using RT-PCR to is...

journal_title：Neuroreport

authors： Singer MS,Hughes TE,Shepherd GM,Greer CA

更新日期：1998-11-16 00:00:00

abstract：:A lexical decision experiment was conducted while event related potentials (ERPs) were recorded. The word frequency and the first syllable frequency of each word were manipulated. Results showed that, while high frequency words produced less negative amplitudes in the N400 time window than low frequency words, the inv...

journal_title：Neuroreport

authors： Barber H,Vergara M,Carreiras M

更新日期：2004-03-01 00:00:00

abstract：:The present study examined the effect of peripherally applied morphine and GABA on jaw muscle electromyographic activity reflexly evoked by co-injection of glutamate into the temporomandibular joint (TMJ) of lightly anesthetized Sprague-Dawley rats of both sexes. In male but not female rats, morphine significantly sup...

journal_title：Neuroreport

authors： Cai BB,Cairns BE,Sessle BJ,Hu JW

更新日期：2001-11-16 00:00:00

abstract：:Myelin basic proteins (MBPs) have been shown to be ADP-ribosylated in-vitro by cholera toxin in the presence of NAD. Since acid-soluble extracts of brain contain other proteins in the 14-32 kD range (such as histones) in addition to MBP's, the identification of the ADP-ribosylated proteins was uncertain. To determine ...

journal_title：Neuroreport

authors： Boulias C,Moscarello MA

更新日期：1990-11-01 00:00:00

abstract：:Single-pulse unilateral electrical stimulation of either the amygdala or the inferior colliculus elicited startle-like responses in chloral hydrate anesthetized rats. EMG responses to intracranial stimulation were recorded from the anterior biceps femoris muscles. The EMG responses were generally enhanced following un...

journal_title：Neuroreport

authors： Lin C,Wan X,Zhao W,Ma C,Ma C,Gao Y,Zhou Y,Yeomans JS,Li L

更新日期：2002-10-07 00:00:00

abstract：:HEL 92.1.7 cells were immobilized among nerve growth factor (NGF)-differentiated PC12 cells. Nicotine caused an immediate Ca2+ mobilisation in the PC12 cells followed by a delayed secondary Ca2+ response in the HEL 92.1.7 cells. The Ca2+ elevation in response to nicotine in PC12 cells was abolished by Na+ removal. The...

journal_title：Neuroreport

authors： Krjukova J,Akerman KE

更新日期：2002-07-02 00:00:00

abstract：:Prior work has shown that kappa opioids may attenuate the effects of analgesic mu receptor agonists in some neural circuits related to pain modulation. This study examined whether hypoalgesia following exposure to a signal for shock is attenuated by infusions of the kappa agonist U69593 into the rostral ventromedial m...

journal_title：Neuroreport

authors： Foo H,Helmstetter FJ

更新日期：2000-10-20 00:00:00

abstract：:Reward-processing neurocircuitry has been delineated using verbal or visual processing and/or decision-making tasks. We examined more basic processes of listening to enjoyable music in healthy and depressed patients. The paradigm was passive, individualized, and brief. Sixteen depressed and 15 control individuals prov...

journal_title：Neuroreport

authors： Osuch EA,Bluhm RL,Williamson PC,Théberge J,Densmore M,Neufeld RW

更新日期：2009-08-26 00:00:00

abstract：:Activity of calpains and caspase-3 inferred from proteolysis of the cytoskeletal protein alpha-spectrin into signature spectrin breakdown products (SBDPs) was used to provide the first systematic and simultaneous comparison of changes in activity of these two families of cysteine proteases after traumatic brain injury...

journal_title：Neuroreport

authors： Pike BR,Zhao X,Newcomb JK,Posmantur RM,Wang KK,Hayes RL

更新日期：1998-08-03 00:00:00

abstract：:Histamine-related drugs are commonly used in the treatment of vertigo and related vestibular disorders. Their site and mechanism of action, however, are still poorly understood. To increase our knowledge of the histaminergic system in the vestibular organs, we have investigated the expression of H1 and H3 histamine re...

journal_title：Neuroreport

authors： Botta L,Tritto S,Perin P,Laforenza U,Gastaldi G,Zampini V,Zucca G,Valli S,Masetto S,Valli P

更新日期：2008-03-05 00:00:00

abstract：:The cellular distribution of the rat metabotropic glutamate receptor type 4 (mGluR4) was examined in the adult rat cerebral cortex and hippocampus. Antibodies were raised against amino acid residues located in the extracellular amino terminal domain that is common to both the mGluR4a and mGluR4b splice variants, and u...

journal_title：Neuroreport

authors： Phillips T,Makoff A,Brown S,Rees S,Emson P

更新日期：1997-10-20 00:00:00

abstract：:Removal of the labyrinthine organs on one side results in static and dynamic disturbances. Some functional recovery occurs over time and is paralleled in frogs by an increase in the efficacy of central vestibular pathways. Here, we report concomitant increases in dorsal root evoked ventral root responses in the brachi...

journal_title：Neuroreport

authors： Straka H,Kunkel A,Dieringer N

更新日期：1993-09-01 00:00:00

abstract：:It has been suggested that high levels of prenatal testosterone exposure are implied in the aetiology of dyslexia and its frequently co-occurring sensory problems. This study examined 2D : 4D digit ratio (a marker of fetal testosterone exposure) in dyslexic and normal reading children. No group differences in 2D : 4D ...

journal_title：Neuroreport

authors： Boets B,De Smedt B,Wouters J,Lemay K,Ghesquière P

更新日期：2007-09-17 00:00:00

abstract：:Extracellular pH transients were evoked in rat hippocampal brain slices by activation of a monosynaptic inhibitory pathway following pharmacological blockade of glutaminergic transmission. Repetitive stimulation in stratum radiatum near the recording site in stratum pyramidale evoked an immediate alkaline shift which ...

journal_title：Neuroreport

authors： Kaila K,Paalasmaa P,Taira T,Voipio J

更新日期：1992-01-01 00:00:00

abstract：:Whereas in the mature retina the glutamate agonist 2-amino-4-phosphonobutyric acid (APB) selectively activates currents in rod bipolar and ON-cone bipolar cells, recent molecular studies have suggested the possibility of a transient appearance of the APB-sensitive receptor in developing retinal ganglion cells. In the ...

journal_title：Neuroreport

authors： Liets LC,Chalupa LM

更新日期：1996-11-25 00:00:00

abstract：:We demonstrate the use of magnetic resonance imaging (MRI) for detection of neurotransmitter stimulation using the dopamine transporter ligands amphetamine and CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane) as pharmacological challenges. We demonstrate that the unilateral loss of a hemodynamic response to eith...

journal_title：Neuroreport

authors： Chen YI,Brownell AL,Galpern W,Isacson O,Bogdanov M,Beal MF,Livni E,Rosen BR,Jenkins BG

更新日期：1999-09-29 00:00:00

abstract：:Metabolic hypofunction is a common finding in a number of neurodegenerative diseases, including Alzheimer's disease (AD). The strong linkage between the amyloid precursor protein (APP) and AD led us to examine whether over-expression of this protein in CNS-type cells had an effect on mitochondria. We found abnormal mo...

journal_title：Neuroreport

authors： Grant SM,Shankar SL,Chalmers-Redman RM,Tatton WG,Szyf M,Cuello AC

更新日期：1999-01-18 00:00:00

abstract：:The present study used the N400, an electrophysiological correlate of semantic processing, to investigate 19- and 24-month-old children's ability to integrate the meaning of words in a sentential context. Children listened passively to semantically appropriate sentences and to sentences in which the object noun violat...

journal_title：Neuroreport

authors： Friedrich M,Friederici AD

更新日期：2005-11-07 00:00:00

abstract：:It is well established that re-exposure to a context paired with the effects of drugs of abuse can renew extinguished drug seeking behavior. A context, however, typically includes several stimuli, which may differ in their ability to control drug-oriented behaviors. Hence, the primary objective of this study was to as...

journal_title：Neuroreport

authors： Cummins E,Boughner E,Leri F

更新日期：2014-03-26 00:00:00

abstract：:Myelinated nerve fibers exhibit a complex anatomy in the nodal region which includes a marked nodal-paranodal constriction and an intricate paranodal structure where the myelin sheath is separated from the axon by a narrow periaxonal space. In this study, a recently developed computational model of the mammalian myeli...

journal_title：Neuroreport

authors： Halter JA,Clark JW Jr

更新日期：1993-01-01 00:00:00

abstract：:Several neurophysiological studies have highlighted the role of the midbrain periaqueductal gray matter (PAG) in the initiation of vocalization in various animal species, from frogs to primates. With regard to humans, only two cases of complete mutism following a lesion to the PAG have been reported so far. This artic...

journal_title：Neuroreport

authors： Esposito A,Demeurisse G,Alberti B,Fabbro F

更新日期：1999-03-17 00:00:00

abstract：:High concentrations of local anesthetics are neurotoxic, but the mechanism for this neurotoxicity is obscure. Here, we report increased concentrations of glutamate in the cerebrospinal fluid after intrathecal injections of high concentrations of tetracaine (a local anesthetic). The peak concentrations of glutamate aft...

journal_title：Neuroreport

authors： Ohtake K,Matsumoto M,Wakamatsu H,Kawai K,Nakakimura K,Sakabe T

更新日期：2000-04-07 00:00:00

abstract：:The present study examined species differences in spatial and non-spatial memory in the Morris water maze. Male Wistar rats and C57BL/6 mice were tested in a one-day water maze task in which spatial learning, retention, and non-spatial learning were assessed within 3 h. Rats and mice appeared to use different strategi...

journal_title：Neuroreport

authors： Frick KM,Stillner ET,Berger-Sweeney J

更新日期：2000-11-09 00:00:00

abstract：:Adult male hamsters and rats were reared for 2 months in either an isolated condition (IC) or a social condition (SC). The lengths of synaptic active zones (SAZ) of synapses in the granule cell layer of the accessory olfactory bulb were measured as an indicator of synaptic size in perforated and non-perforated synapse...

journal_title：Neuroreport

authors： Matsuoka M,Mori Y,Ichikawa M

更新日期：1996-10-02 00:00:00

abstract：:Evidences in the central nervous system are in favor that adenosine under basal conditions is released by a direct excitation-secretion modality. However, till now, there is no direct evidence that adenosine is contained in synaptic vesicles. Eight synaptic vesicle fractions were recovered on a discontinuous sucrose g...

journal_title：Neuroreport

authors： Corti F,Cellai L,Melani A,Donati C,Bruni P,Pedata F

更新日期：2013-12-04 00:00:00

abstract：:The Stroop effect refers to an increase in response time observed when the word meaning and the stimulus hue do not match. In an incongruent condition, the word 'green' is presented in the color red, whereas in a congruent condition the word 'red' is presented in the color red. To determine at what level of processing...

journal_title：Neuroreport

authors： Xiao X,Qiu J,Zhang Q

更新日期：2009-05-06 00:00:00

abstract：:In marked contrast to several other species, including rats and humans, leptin gene expression is undetectable in mouse brain. This unexpected finding may reflect unique energy regulation pathways in the mouse. We investigated possible mechanisms by which leptin (ob) gene expression is suppressed in mouse brain: (a) t...

journal_title：Neuroreport

authors： Brown RE,Wilkinson DA,Wilkinson PM,Imran SA,Wilkinson M

更新日期：2012-10-24 00:00:00