Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury.

abstract：:The so-called 40 Hz oscillations are found at almost all stages of visual processing are thought to play a critical role in perception. The goal of this investigation was to look at the presence of stimulus-specific oscillations in the lateral posterior-pulvinar complex of the thalampus (LP-P) for which the oscillatio...

journal_title：Neuroreport

authors： Shumikhina S,Molotchnikoff S

更新日期：1995-11-27 00:00:00

abstract：:We studied whether pro-survival Akt was activated after transient focal cerebral ischemia and whether it inhibited pro-apoptotic Bad. Phosphorylation of Akt (serine-473) was enhanced in cortex after 1-hour ischemia, and also after 1h and 6 h of reperfusion, but it returned back to that in controls by 24 h. After this ...

journal_title：Neuroreport

authors： Friguls B,Justicia C,Pallàs M,Planas AM

更新日期：2001-10-29 00:00:00

abstract：:In the visual modality adaptation to high temporal frequency can result in spatially localized apparent duration compression. The principal point of adaptation is thought to be early in the visual system, at which point temporal information is encoded within sustained (parvocellular) and transient (magnocellular) chan...

journal_title：Neuroreport

authors： Watanabe J,Amemiya T,Nishida S,Johnston A

更新日期：2010-09-15 00:00:00

abstract：:Optical imaging of rat barrel cortex has provided detailed spatio-temporal maps of functional cortical architecture. We describe an event-related procedure (ERP) for optical imaging based on selective signal averaging as reported by Burock et al., using an anti-correlative pseudo-random event sequence. The sequence us...

journal_title：Neuroreport

authors： Martindale J,Berwick J,Johnston D,Jones M,Zheng Y,Coffey P,Paley M,Mayhew J

更新日期：2000-07-14 00:00:00

abstract：:Animal studies have shown brain ischaemia to cause oxidative damage to DNA and activation of caspase-3, leading to apoptosis. These changes may be exacerbated by reperfusion. To assess caspase-3 activation after transient and permanent brain ischaemia in man, we examined brain tissue from patients who had experienced ...

journal_title：Neuroreport

authors： Love S,Barber R,Srinivasan A,Wilcock GK

更新日期：2000-08-03 00:00:00

abstract：:Brain trauma induces a multitude of reactions at molecular, cellular, and tissue levels, some of which are beneficial to recovery, whereas others are detrimental. Osteopontin (OPN), a glycosylated phosphoprotein, can be found in both the soluble form and as an extracellular matrix constituent in several tissues in the...

journal_title：Neuroreport

authors： Plantman S

更新日期：2012-08-01 00:00:00

abstract：:The gene expression of cholecystokinin (CCK), a neuropeptide with anti-opioid properties, has been reported to be upregulated in some primary sensory neurons after a peripheral nerve lesion. We have recently demonstrated that the upregulation of CCK mRNA is not accompanied by an increased potassium-evoked release CCK-...

journal_title：Neuroreport

authors： Afrah AW,Gustafsson H,Olgart L,Brodin E,Stiller CO

更新日期：2001-01-22 00:00:00

abstract：:Transient global amnesia (TGA), characterised by a profound anterograde amnesia, is a model of interest to study the acquisition of novel meanings independent of episodic functioning. Three patients were tested during a TGA attack, two in the early recovery phase and the third during the acute phase of TGA, with a sem...

journal_title：Neuroreport

authors： Guillery B,Desgranges B,Katis S,de la Sayette V,Viader F,Eustache F

更新日期：2001-12-04 00:00:00

abstract：:Immunohistochemistry for calcitonin gene-related peptide (CGRP) was performed on the dorsal root ganglion (DRG) and spinal cord in wildtype and knockout mice for Brn-3a. CGRP-immunoreactive (-IR) neurons were abundant in the DRG of wildtype, heterozygous and knockout mice. Cell size analysis revealed that CGRP-IR neur...

journal_title：Neuroreport

authors： Ichikawa H,Yamaai T,Mo Z,Xiang M,Sugimoto T

更新日期：2002-03-25 00:00:00

abstract：:The ventral cochlear tract in the brain stem to pons was transected on one side in two groups of adult rats. In one group simple transection was performed, while in the other group tissue from embryos (E14-E16) was used to cover the lesion site. While rats receiving simple transection without transplantation showed no...

journal_title：Neuroreport

authors： Ito J,Kawaguchi S,Murata M

更新日期：1998-12-01 00:00:00

abstract：:The study was conducted to investigate the effect of serotonin depletion on nitric oxide-induced meningeal vascular response and cerebrovascular nociception. Nitroglycerin was infused i.v. to control and serotonin-depleted rats. Pial circulation was monitored by intravital fluorescent videomicroscopy and Fos immunorea...

journal_title：Neuroreport

authors： Srikiatkhachorn A,Anuntasethakul T,Phansuwan-Pujito P,Patumraj S,Kasantikul V

更新日期：2001-04-17 00:00:00

abstract：:Currents from the slowly adapting stretch receptor neuron of the crayfish (Pacifastacus leniusculus) were studied in a cell attached configuration using patch pipettes with an opening diameter of 2-10 microm. The neuronal membrane was enzymatically freed from the glial layer. The voltage gated Na+ and K+ channels seem...

journal_title：Neuroreport

authors： Lin JH,Sand P,Rydqvist B

更新日期：1999-08-20 00:00:00

abstract：:Resident microglial cells contribute to activation and expansion of T cells under inflammatory conditions within the CNS. However, there is no evidence how interactions between microglia and T cells affect CNS inflammation. We evaluated the effect of glial cell-derived dendritic cells (GC-DC) in expanding and eliminat...

journal_title：Neuroreport

authors： Xu LY,Yang JS,Xiao BG

更新日期：2002-01-21 00:00:00

abstract：:The balance between heat production (metabolism) and heat removal (blood flow) helps in keeping the temperature of the brain constant. In patients with moyamoya disease, this balance may be disturbed. The purpose of this study was to assess the thermal pathophysiology of the brain in patients with moyamoya disease. Th...

journal_title：Neuroreport

authors： Yamada K,Sakai K,Akazawa K,Yuen S,Sugimoto N,Sasajima H,Mineura K,Nishimura T

更新日期：2010-09-15 00:00:00

abstract：:Methamphetamine (METH)-induced dopaminergic neurotoxicity is associated with hyperthermia. We investigated the effect of several neuronal nitric oxide synthase (nNOS) inhibitors on METH-induced hyperthermia and striatal dopaminergic neurotoxicity. Administration of METH (5 mg/kg; q. 3 h x 3) to Swiss Webster mice prod...

journal_title：Neuroreport

authors： Itzhak Y,Martin JL,Ail SF

更新日期：2000-09-11 00:00:00

abstract：:The functions of the fields of the mammalian auditory cortex in sound perception and recognition are unknown. We used Fos (a protein of the inducible immediate-early gene c-fos) as a cellular marker of activated brain areas to show in the mouse (Mus domesticus) that sound is processed differentially in auditory cortic...

journal_title：Neuroreport

authors： Fichtel I,Ehret G

更新日期：1999-08-02 00:00:00

abstract：:Multiple signal classification is an alternative to the traditional dipole fitting source analysis methods. Our aim was to assess the clinical usefulness of this algorithm and to compare the localization of the epileptiform electroencephalography discharges with the regions of altered cerebral blood flow in 10 patient...

journal_title：Neuroreport

authors： Beniczky S,Oturai PS,Alving J,Sabers A,Herning M,Fabricius M

更新日期：2006-08-21 00:00:00

abstract：:Matrix metalloproteinase-9 (MMP-9) and its specific inhibitor, tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), were analysed by enzyme-linked immunosorbent assay (ELISA) and by zymography in serum and cerebrospinal fluid (CSF) of patients with amyotrophic lateral sclerosis (ALS). In contrast to patients with ...

journal_title：Neuroreport

authors： Beuche W,Yushchenko M,Mäder M,Maliszewska M,Felgenhauer K,Weber F

更新日期：2000-11-09 00:00:00

abstract：:Decoding verbal and nonverbal emotional expressions is an important part of speech communication. Although various studies have tried to specify the brain regions that underlie different emotions conveyed in speech, few studies have aimed to specify the time course of emotional speech decoding. We used event-related p...

journal_title：Neuroreport

authors： Paulmann S,Kotz SA

更新日期：2008-01-22 00:00:00

abstract：:This study demonstrates the neural system potentially involved in the representation of, and choice between, stimulus classifications in an ambiguous, novel, decision-making task. This difficult choice behaviour is taken as an example of a basic executive processing task. Subjects heard sounds that were consonant-vowe...

journal_title：Neuroreport

authors： Scott SK,Holmes A,Friston KJ,Wise RJ

更新日期：2000-05-15 00:00:00

abstract：:Evidence of glutamatergic dysfunction in schizophrenia associated with the N-methyl-D-aspartate receptor has historically demonstrated changes primarily attributable to neurons. We propose an astrocytic component to N-methyl-D-aspartate receptor dysfunction in this illness. We studied the expression of serine racemase...

journal_title：Neuroreport

authors： Steffek AE,Haroutunian V,Meador-Woodruff JH

更新日期：2006-07-31 00:00:00

abstract：:Compartmental models of thalamic reticular (RE) neurons were investigated based on current-clamp and voltage-clamp data. Spontaneous oscillations in the model arise from the interaction between inhibitory synaptic currents and the rebound burst of RE cells. These oscillations critically depend on the level of the rest...

journal_title：Neuroreport

authors： Destexhe A,Contreras D,Sejnowski TJ,Steriade M

更新日期：1994-11-21 00:00:00

abstract：:Recent studies on cerebrospinal fluid (CSF) homeostasis emphasize the importance of water flux through the pericapillary (Virchow-Robin) space for both CSF production and reabsorption (Oreskovic and Klarica hypothesis), and challenge the classic CSF circulation theory, which proposes that CSF is primarily produced by ...

journal_title：Neuroreport

authors： Igarashi H,Tsujita M,Kwee IL,Nakada T

更新日期：2014-01-08 00:00:00

abstract：:Intraplantar carrageenan induced a peripheral oedema and c-Fos like immunoreactivity (Fos-LI) in L4-L5 segments in the dorsal horn (DH) of the rat spinal cord. The total number of carrageenan evoked Fos-LI neurones was 153 +/- 10 per section, with a predominant localization in the superficial and deep laminae of the D...

journal_title：Neuroreport

authors： Buritova J,Honoré P,Chapman V,Besson JM

更新日期：1995-07-10 00:00:00

abstract：:The functional integrity of the 'on' and 'off' neurovisual pathways has been examined in the central visual fields of normal (n = 13), glaucomatous (n = 21) and ocular hypertensive (n = 21) individuals. The detection thresholds to light increments (onsets = bright spots) and light decrements (offsets = dark spots) on ...

journal_title：Neuroreport

authors： Mutlukan E

更新日期：1993-09-03 00:00:00

abstract：:The hippocampus is well known to contribute to episodic memory encoding. Here we used functional magnetic resonance imaging to investigate the hippocampal response to exponentially varying encoding demands while forming associations between faces and names. We found that only the left hippocampus exhibited a stepped m...

journal_title：Neuroreport

authors： Ulrich M,Jonas C,Grön G

更新日期：2010-01-06 00:00:00

abstract：:Hindlimb unloading (HU) can cause motion and cognition dysfunction, although its cellular and molecular mechanisms are not well understood. The aim of the present study was to determine the stereological parameters of the brain areas involved in motion (motor cortex) and spatial learning - memory (hippocampus) under a...

journal_title：Neuroreport

authors： Salehi MS,Mirzaii-Dizgah I,Vasaghi-Gharamaleki B,Zamiri MJ

更新日期：2016-11-09 00:00:00

abstract：:The localization of PKC gamma mRNA expression during the maturation of rat cerebellum has been studied by in situ hybridization. We found a transient expression over the granule cell layer and persistent high expression in the Purkinje cells during postnatal development. Expression in granule cells appeared as early a...

journal_title：Neuroreport

authors： Herms J,Zurmöhle U,Schlingensiepen KH,Brysch W

更新日期：1993-07-01 00:00:00

abstract：:Whole-cell recordings in voltage-clamp mode were performed on acutely isolated neurones from rat neocortex and neostriatum to examine the effects of the anticonvulsant phenytoin on a non-inactivating (persistent) Na+ current (INaP). INaP was chosen because it enhances neuronal excitability near firing threshold, which...

journal_title：Neuroreport

authors： Chao TI,Alzheimer C

更新日期：1995-09-11 00:00:00

abstract：:In the present study, changes in the cytokine system (IL-1 beta, IL-2, IL-3, IL-6 and TNF alpha) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNF alpha, a decrease in that of IL-2 and of IL-3 with no change in IL-1 beta and in IL-6 secretion lev...

journal_title：Neuroreport

authors： Mittwoch-Jaffe T,Shalit F,Srendi B,Yehuda S

更新日期：1995-03-27 00:00:00