Abstract:
:Currents from the slowly adapting stretch receptor neuron of the crayfish (Pacifastacus leniusculus) were studied in a cell attached configuration using patch pipettes with an opening diameter of 2-10 microm. The neuronal membrane was enzymatically freed from the glial layer. The voltage gated Na+ and K+ channels seemed to be more concentrated in the lower part of soma close to the axon hillock. The Na+ and K+ currents could be analysed by fitting the currents to a fourth-order exponential function for Na+ current and a second-order exponential function for the K+ current. The macropatch recordings of enzymatically treated neurons are superior to two electrode voltage clamp recordings when analyzing voltage gated Na+ and K+ currents.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Lin JH,Sand P,Rydqvist Bdoi
10.1097/00001756-199908200-00013subject
Has Abstractpub_date
1999-08-20 00:00:00pages
2503-7issue
12eissn
0959-4965issn
1473-558Xjournal_volume
10pub_type
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