Abstract:
:Transient global amnesia (TGA), characterised by a profound anterograde amnesia, is a model of interest to study the acquisition of novel meanings independent of episodic functioning. Three patients were tested during a TGA attack, two in the early recovery phase and the third during the acute phase of TGA, with a semantic priming task involving a restructuring process of conceptual knowledge. During TGA, all patients demonstrated priming effects. Results obtained the day after the episode with the same task showed that these effects persisted at least one day. Episodic memory seems not to be critical for the formation of novel connections among unrelated semantic representations, in accordance with Tulving's model of memory, i.e. episodic memory is not necessary for the acquisition of semantic information.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Guillery B,Desgranges B,Katis S,de la Sayette V,Viader F,Eustache Fdoi
10.1097/00001756-200112040-00052subject
Has Abstractpub_date
2001-12-04 00:00:00pages
3865-9issue
17eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Adrenocorticotropic hormone (ACTH) is a member of the opiocortin family of peptides. Within the central nervous system, ACTH-synthesizing neurons are generally considered to be located within the hypothalamus and are known to be involved in the neural circuitry underlying the integration of stress responses. We now re...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199202000-00001
更新日期:1992-02-01 00:00:00
abstract::We obtained visual response latencies and response durations following visual stimulation of neurones recorded in the lateral geniculate nucleus (LGN), areas 17, 18, 19, the posteromedial lateral suprasylvian sulcus (PMLS), and area 7 of the cat. We found an increasing lengthening of the mean response latencies, consi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199404000-00010
更新日期:1994-04-14 00:00:00
abstract::Autophosphorylation of the alpha-isoform of Ca2+/calmodulin-dependent kinase II switches the kinase into an autonomous activity mode. This molecular switch is important for hippocampal long-term memory formation, which requires de novo gene transcription and protein synthesis. Here, we have studied whether auto-phosph...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175244.51084.bb
更新日期:2005-08-22 00:00:00
abstract::Correcting for eddy currents, movement-induced distortion and gradient inhomogeneities is imperative when processing diffusion MRI (dMRI) data, but is highly computing resource-intensive. Recently, Compute Unified Device Architecture (CUDA) was implemented for the widely-used eddy-correction software, 'eddy', which re...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001475
更新日期:2020-07-10 00:00:00
abstract::Five patients with left visual neglect after right hemisphere lesions were examined with a line bisection and a reading task under five different conditions: head and trunk straight ahead, head or trunk oriented 20 degrees to the left and head or trunk oriented 20 degrees to the right. Fixation was always straight ahe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199708180-00009
更新日期:1997-08-18 00:00:00
abstract::Infection with human immunodeficiency virus (HIV)-1 can lead to neurological complications that range from mild cognitive and motor impairment to HIV-associated dementia (HAD). The mechanism of brain injury and dementia remains poorly understood. Interestingly, post mortem brain specimen from HAD patients and transgen...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200404090-00004
更新日期:2004-04-09 00:00:00
abstract::Cells overexpressing the beta-amyloid precursor protein possessing a mutation found in familial Alzheimer's disease overproduce beta-amyloid peptide (A beta). Because these findings were based on immunological identification, we have chemically characterized the peptides produced. Purified A beta fragments from the co...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199308000-00011
更新日期:1993-08-01 00:00:00
abstract::Microglial activation is thought to contribute to the progression of selective motor neuron death during amyotrophic lateral sclerosis (ALS). As minocycline has been shown to inhibit microglial activation, the therapeutic efficacy of this tetracycline derivative in the G93A mice model for familial ALS was tested. This...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200206120-00018
更新日期:2002-06-12 00:00:00
abstract::Satiety signals from the gastrointestinal tract travel via vagal afferents to the nucleus of the solitary tract (NTS) in the brain stem, the first central relay in a neural network which controls food intake. The non-competitive NMDA antagonist MK-801 facilitates food intake in rats by acting on the NTS. Here we repor...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200008210-00002
更新日期:2000-08-21 00:00:00
abstract::Adrenomedullin (ADM) is a 52 amino acid peptide with multiple physiological functions and wide tissue distributions including brain. Recently, elevated plasma levels of ADM were found in patients with schizophrenia, bipolar affective disorder and autism, suggesting the involvement of ADM in the pathophysiology of ment...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000132202.69212.79
更新日期:2004-06-28 00:00:00
abstract::The present study reveals the presence of a distinct group of cells, resembling reticular thalamic neurones, in the internal capsule during fetal development. This cell population rapidly decreases in size during early infancy and few cells are apparent in the 1-year-old infant. Internal capsule cells are well differe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1996-09-02 00:00:00
abstract::We examined the positioning of human retinotopic areas, which were considered to be homologous with the macaque visual cortices, by applying computational geometry to MRI and fMRI data sets. We found a similarity between the positional relationship of the retinotopic areas in the human and macaque visual cortex, despi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200501190-00003
更新日期:2005-01-19 00:00:00
abstract::NONINVASIVE photolytic injury to targeted neuronal subpopulations in vivo causes unique, slowly progressive neuronal degeneration. To examine the mechanisms of degeneration toward development and transplantation studies, cytosolic calcium levels were measured in vitro from neocortical neurons after incorporation of ph...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199208000-00014
更新日期:1992-08-01 00:00:00
abstract::Elevations of cytosolic free Ca2+ concentration ([Ca2+]i) induced by addition of ATP have been compared in rat dorsal horn neurones in slices and after their isolation. ATP application induced in neurones in situ a rise of [Ca2+]i by 201 +/- 12 nM. In Ca2+-free external solution the rise was 156 +/- 14 nM (n = 45 of 7...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200111160-00026
更新日期:2001-11-16 00:00:00
abstract::Counter-stimulation reduces pain perception; however, the role of attention during this process is rarely discussed despite attention itself being a well known modulator of pain perception. This study investigated the effect of attentional modulation on pain perception during counter-stimulation using fMRI. Subjects r...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200107030-00047
更新日期:2001-07-03 00:00:00
abstract::Calpain activation has been implicated in the pathogenesis of Alzheimer's disease. Okadaic acid, a protein phosphatase-2A inhibitor, has been used in Alzheimer's disease research models to increase tau phosphorylation and induce neuronal death. We previously reported that okadaic acid induced predominant activation of...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000214398.04093.7f
更新日期:2006-05-15 00:00:00
abstract::We injected neural tracers into the lateral funiculus of the spinal cord in order to relate the sites of origin of the spinal projections from the mesial cortical surface with the cytoarchitectonic organization of this region. We found a close correlation between the origin sites and density of corticospinal projectio...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199412000-00035
更新日期:1994-12-20 00:00:00
abstract::Interleukin-2 and its receptors are present in hippocampal structures, particularly the pyramidal cell layer. In the present study, we examined the interaction between recombinant human interleukin-2 (rhIL-2) and the voltage-dependent calcium (Ca2+) current using the whole-cell patch-clamp technique. RhIL-2 depressed ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199305000-00030
更新日期:1993-05-01 00:00:00
abstract::Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) are assumed to provide trophic support via a target-derived, retrograde mechanism of action. However, recent studies suggest that neurotrophic factors can act in an autocrine fashion and perhaps even in an anterograde direction similar to neurotrans...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199705260-00008
更新日期:1997-05-27 00:00:00
abstract::EphA5 and its ligand ephrin-A5 interaction can trigger synaptogenesis during early hippocampus development. We have previously reported that abnormal EphA5 expression can result in synaptogenesis disorder in congenital hypothyroidism (CH) rats. To better understand its precise molecular mechanism, we further analyzed ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001047
更新日期:2018-08-01 00:00:00
abstract::The interaction of vestibular inputs with different dynamic and spatial behavior, i.e., canal-otolith interaction, leads to spatio-temporal convergence. Vestibular neurons in the fastigial nucleus often exhibit spatio-temporal convergence. The present report demonstrates that the discharge rates of most vestibular neu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200205070-00013
更新日期:2002-05-07 00:00:00
abstract::Echo-Planar functional magnetic resonance imaging (EP-fMRI) was used to study the activity of the amygdala while three normal female subjects viewed alternating blocks of affectively neutral and affectively negative still pictures. Bilateral activation in the amygdala that was significantly correlated with the changin...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199607290-00014
更新日期:1996-07-29 00:00:00
abstract::Hyperbaric oxygen (HBO) therapy and neural stem cell (NSC) transplantation can improve traumatic brain injury (TBI) clinically. This study aimed to investigate the mechanism of HBO promoting NSC proliferation and neurological recovery after TBI. Twenty-four Sprague-Dawley rats were divided randomly into three groups: ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000901
更新日期:2017-12-13 00:00:00
abstract::In the present study, we tested the hypothesis that interleukin (IL)-10 down-regulates human microglial cell IL-8 release by inhibiting activation of nuclear factor kappa B (NF-kappaB). Immunohistochemical staining demonstrated that IL-10 markedly suppressed lipopolysaccharide (LPS)- and IL-1beta-stimulated IL-8 expre...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199806010-00010
更新日期:1998-06-01 00:00:00
abstract::Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, how...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833fcba4
更新日期:2010-11-17 00:00:00
abstract::Factors controlling proliferation and differentiation are crucial in advancement of neural cell-based experimental neurodegenerative therapies. In this regard, nicotinamide has been shown to determine the fate of neural cells, enhance neuralization, and influence DNA repair and apoptosis. This study investigated wheth...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000071
更新日期:2013-12-18 00:00:00
abstract::The mechanism by which IL-1 beta exerts its actions in the brain during systemic inflammation is not fully understood, as neither IL-1 receptor gene expression nor IL-1 binding have been identified in significant levels in key areas that respond to IL-1 beta. Having hypothesized that perivascular nitric oxide (NO) mig...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199611040-00008
更新日期:1996-11-04 00:00:00
abstract::The regulation of glucocorticoid receptors and nuclear factor kappaB was evaluated in the spiral ganglion neurons after 4 h of restraint stress in the mouse cochlea. Immediately after restraint stress, glucocorticoid receptor protein expression was not altered in spiral ganglion neurons even though both the plasma cor...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000220131.24468.e7
更新日期:2006-06-26 00:00:00
abstract::Epidemiological data show correlations between hypercholesterolemia and Alzheimer's disease (AD). We test the hypothesis that hypercholesterolemia modulates Abeta deposition in mice overexpressing the human APP695 Swedish mutation (K670N and M671L) (TgAPPsw). Feeding mice a high fat/high cholesterol (HFHC) diet for 7-...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200203250-00019
更新日期:2002-03-25 00:00:00
abstract::Maintenance of long-term potentiation in perforant path-granule cell synapses is accompanied by increased glutamate release. Here we investigate the role of synaptophysin in release and in expression of long-term potentiation in dentate gyrus. We report that long-term potentiation was accompanied by increased endogeno...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199808030-00012
更新日期:1998-08-03 00:00:00