Transient neuronal population of the internal capsule in the developing human cerebrum.

abstract：:Maintenance of long-term potentiation in perforant path-granule cell synapses is accompanied by increased glutamate release. Here we investigate the role of synaptophysin in release and in expression of long-term potentiation in dentate gyrus. We report that long-term potentiation was accompanied by increased endogeno...

journal_title：Neuroreport

authors： Mullany PM,Lynch MA

更新日期：1998-08-03 00:00:00

abstract：:The aim of this study was to investigate distinct neurometabolites in the right and left thalamus and insula of patients with complex regional pain syndrome (CRPS) compared with healthy controls using proton magnetic resonance spectroscopy. Levels of N-acetylaspartate (NAA), N-acetylaspartylglutamate (NAAG), myo-inosi...

journal_title：Neuroreport

authors： Jung YH,Kim H,Jeon SY,Kwon JM,Kim YC,Lee WJ,Lee D,Lee JY,Moon JY,Kang DH

更新日期：2019-01-16 00:00:00

abstract：:Amyloid beta-peptide (Abeta) accumulation in aged Sprague-Dawley rats (12 months) with kaolin-induced hydrocephalus was investigated by Abeta(1-40) and Abeta(1-42) immunohistochemistry at 2, 6 and 10 weeks after induction. The low-density lipoprotein receptor-related protein-1 transporting Abeta across the blood-brain...

journal_title：Neuroreport

authors： Klinge PM,Samii A,Niescken S,Brinker T,Silverberg GD

更新日期：2006-04-24 00:00:00

abstract：:Neuronal network reconstruction is a pivotal determinant for functional recovery after spinal cord injury (SCI), the process of which includes synaptogenesis. Slit2 protein has been identified as a key regulator of axon regeneration and synapse formation in the vertebrate. Meanwhile, RhoA is the converging cascade of ...

journal_title：Neuroreport

authors： Li Y,Gao Y,Xu X,Shi R,Liu J,Yao W,Ke C

更新日期：2017-01-18 00:00:00

abstract：:NMR signal intensities in five regions of the midsagittal corpus callosum were measured in autism patients and normal controls. An age-related increase in signal was observed in the anterior regions in both groups. No significant differences in intensity were detected between the groups. The finding of normal myelinat...

journal_title：Neuroreport

authors： Belmonte M,Egaas B,Townsend J,Courchesne E

更新日期：1995-06-19 00:00:00

abstract：:N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...

journal_title：Neuroreport

authors： Montag-Sallaz M,Montag D,Schachner M

更新日期：2003-07-18 00:00:00

abstract：:Piccolo is one of the components of the active zone at chemical synapses and regulates the transport of synaptic vesicles. The piccolo C2A domain is an important calcium sensor and binds with phosphatidylinositol or synaptotagmin-1. Recently, clinical studies suggested that a single nucleotide polymorphism in the picc...

journal_title：Neuroreport

authors： Furukawa-Hibi Y,Nitta A,Fukumitsu H,Somiya H,Furukawa S,Nabeshima T,Yamada K

更新日期：2010-12-29 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) and adrenomedullin are structurally similar neuropeptides acting as potent vasodilators of blood pressure and mediator of inflammation in skin. Revealing the expression pattern of their common receptor-Calcitonin gene-related peptide receptor (Calcrl) in their targeted cells is i...

journal_title：Neuroreport

authors： Gong Y,Wei JP,Wang TH,Zhong HB,Liao XH

更新日期：2020-08-05 00:00:00

abstract：:Muller glial cells of the sensory retina mediate K+ and water fluxes that are facilitated by aquaporin-4 (AQP4) water channels and by Kir4.1-K+ channels. However, it is not known which subtypes of aquaporins are expressed in the mammalian retina. Using RT-PCR, we found that both human and rat retinas express mRNA for ...

journal_title：Neuroreport

authors： Tenckhoff S,Hollborn M,Kohen L,Wolf S,Wiedemann P,Bringmann A

更新日期：2005-01-19 00:00:00

abstract：:Our previous studies have shown that Panax notoginseng saponins (PNS) play a protective role in learning dysfunction of Alzheimer's disease, inhibit the deposition of Aβ1-40 and Aβ1-42, and reduce the content of App in the brain of SAMP8. In this study, we aimed to investigate the effects of PNS on α, β, and γ secreta...

journal_title：Neuroreport

authors： Huang J,Wu D,Wang J,Li F,Lu L,Gao Y,Zhong Z

更新日期：2014-01-22 00:00:00

abstract：:Experimental animals and patients are immobilized to allow continuous monitoring of physiological parameters. Restraint stress affects brain neurotransmitter levels and induces expression of immediate early genes. Whether immobilization stress affects outcomes in newborn animals which have suffered a hypoxic-ischaemic...

journal_title：Neuroreport

authors： Thoresen M,Bågenholm R,Løberg EM,Apriccna F

更新日期：1996-01-31 00:00:00

abstract：:Antisera were produced against synthetic peptides predicted from the recent cloning of a delta opioid receptor, DOR-1. Confocal microscopic examination of immunostained spinal cord sections revealed that DOR-1 immunoreactive (-ir) nerve fibers and terminals form a moderately dense plexus within the superficial dorsal ...

journal_title：Neuroreport

authors： Dado RJ,Law PY,Loh HH,Elde R

更新日期：1993-12-13 00:00:00

abstract：:We examined the electrophysiological correlates of the processing of social exclusion and inclusion by using a modified version of the Cyberball paradigm. Exclusion was found to be associated with a significant increase in the P3 complex. The frontal-central P3a was primarily related to the affective processing of rej...

journal_title：Neuroreport

authors： Gutz L,Küpper C,Renneberg B,Niedeggen M

更新日期：2011-06-22 00:00:00

abstract：:Administration of either a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801 (dizocilpine), or a muscarinic antagonist, scopolamine, produces dose-related impairments in performance of a visual recognition memory task, delayed non-matching to sample (DNMS) with lists of 20 symbols, in rhesus monk...

journal_title：Neuroreport

authors： Matsuoka N,Aigner TG

更新日期：1996-01-31 00:00:00

abstract：:We investigated the cortical activation changes associated with motor recovery in six hemiparetic patients with precentral knob infarct. fMRI at 1.5 T with finger movements at a fixed rate was performed twice in each patient, 1 and 6 months after stroke onset. From the images obtained, the LI (laterality index) for th...

journal_title：Neuroreport

authors： Jang SH,Cho SH,Kim YH,Kwon YH,Byun WM,Lee SJ,Park SM,Chang CH

更新日期：2004-03-01 00:00:00

abstract：:Amyloid beta-peptide (A beta) is a major component of neuritic plaques, a feature of Alzheimer's disease (AD) brains. Recently, we showed that A beta adopts two major conformational states in solution, which differ in their abilities to form amyloid. These are highly amyloidogenic conformer (A beta ac) with a high con...

journal_title：Neuroreport

authors： Soto C,Golabek A,Wisniewski T,Castaño EM

更新日期：1996-02-29 00:00:00

abstract：:Because salicylate is known to produce tinnitus in humans and animals, the effect of salicylate on the auditory system of gerbils was investigated using [14C]2-deoxyglucose (2-DG). Salicylate treatment reduced activity in the inferior colliculus (IC), particularly in the high frequency part, whereas activation along s...

journal_title：Neuroreport

authors： Wallhäusser-Franke E,Braun S,Langner G

更新日期：1996-07-08 00:00:00

abstract：:Hypoxia or global ischemia causes rapid loss of consciousness and a sudden increase in spontaneous transmitter release suggesting that coordinated synaptic activity is impaired. Gamma oscillations (30-100 Hz) are thought to provide for binding of parallel processed information in the brain, contributing to cognition a...

journal_title：Neuroreport

authors： Fano S,Behrens CJ,Heinemann U

更新日期：2007-11-19 00:00:00

abstract：:Immunohistochemical techniques were employed to examine the distribution of RNA-binding proteins A2 and B1 in the rat forebrain. Intense A2 and B1 immunolabeling were observed in the nucleoplasm of the neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamen as well as the supraoptic...

journal_title：Neuroreport

authors： Mizukami K,Kamma H,Ishikawa M,Dreyfuss G

更新日期：2000-09-28 00:00:00

abstract：:Neural plasticity in the visual cortex, as tested by changes in its functional organization induced by monocular deprivation (MD), is present only during a restricted period of postnatal development (critical period). To investigate whether this process of synapse strengthening depends upon NGF, we antagonized endogen...

journal_title：Neuroreport

authors： Domenici L,Cellerino A,Berardi N,Cattaneo A,Maffei L

更新日期：1994-10-27 00:00:00

abstract：:In the current study we explored the relationship between neurometabolites measured by proton magnetic resonance spectroscopy (1H-MRS) and cognitive ability assessed with a battery of neuropsychological tests. Forty-five participants were recruited from the local college community, and examined utilizing neuropsycholo...

journal_title：Neuroreport

authors： Jung RE,Yeo RA,Chiulli SJ,Sibbitt WL Jr,Weers DC,Hart BL,Brooks WM

更新日期：1999-11-08 00:00:00

abstract：:Activity of calpains and caspase-3 inferred from proteolysis of the cytoskeletal protein alpha-spectrin into signature spectrin breakdown products (SBDPs) was used to provide the first systematic and simultaneous comparison of changes in activity of these two families of cysteine proteases after traumatic brain injury...

journal_title：Neuroreport

authors： Pike BR,Zhao X,Newcomb JK,Posmantur RM,Wang KK,Hayes RL

更新日期：1998-08-03 00:00:00

abstract：:Acute arthritis is associated with pain-related behavior, joint swelling and increased joint temperature. Arthritic animals exhibit a significant decrease in paw withdrawal latency 4, 5, 6, 7 and 8 h after induction of inflammation, when compared with baseline values, indicative of secondary hyperalgesia. Intra-articu...

journal_title：Neuroreport

authors： Lawand NB,Willis WD,Westlund KN

更新日期：1997-03-03 00:00:00

abstract：:To observe sequential stages in tactile pattern discrimination and their modification with and without attention, we used whole-head anatomically constrained magnetoencephalography to spatiotemporally map brain responses. Eight, normal, right-handed participants discriminated between two patterns presented on the palm...

journal_title：Neuroreport

authors： Reed CL,Hagler DJ Jr,Marinkovic K,Dale A,Halgren E

更新日期：2009-07-01 00:00:00

abstract：:Inconsistencies in previous attempts to localize the N2 wave in the GO/NOGO task led to the present investigation. The inconsistencies were probably because of heterogeneity of psychological operations involved in GO/NOGO tasks. We applied the independent component analysis to a collection of individual event-related ...

journal_title：Neuroreport

authors： Kropotov JD,Ponomarev VA

更新日期：2009-12-09 00:00:00

abstract：:Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of cerebrovascular diseases. Using organ culture as a model for possible pathological changes we studied changes in ET(A) and ETB receptor function using a sensitive in vitro method. We observed an up-regulation of the ET(B) receptor and an ama...

journal_title：Neuroreport

authors： Hansen-Schwartz J,Edvinsson L

更新日期：2000-02-28 00:00:00

abstract：:The aim of this study was to evaluate the contribution of ionotropic glutamate receptors to kindled seizure-evoked somatostatin release in the hippocampus, using a microdialysis approach. Basal and amygdala stimulation-evoked somatostatin-like immunoreactivity (-LI) release was significantly greater in kindled compare...

journal_title：Neuroreport

authors： Marti M,Bregola G,Binaschi A,Gemignani A,Simonato M

更新日期：2000-09-28 00:00:00

abstract：:Three SNARE proteins, SNAP-25, syntaxin 1A, and VAMP2 or synaptobrevin 2, constitute the minimal functional machinery needed for the regulated secretion of neurotransmitters. Dynamic changes in the regulated release of neurotransmitters are associated with the induction of long-term plasticity at central synapses. In-...

journal_title：Neuroreport

authors： Irfan M,Zurawski Z,Hamm HE,Bark C,Stanton PK

更新日期：2019-07-03 00:00:00

abstract：:To investigate the neurobiological bases of visual hallucinations in dementia with Lewy bodies (DLB), regional cerebral glucose metabolism was compared among three patient groups; DLB with visual hallucinations, DLB without visual hallucinations and Alzheimer's disease (AD) without visual hallucinations. The regional ...

journal_title：Neuroreport

authors： Imamura T,Ishii K,Hirono N,Hashimoto M,Tanimukai S,Kazuai H,Hanihara T,Sasaki M,Mori E

更新日期：1999-06-23 00:00:00

abstract：:Newly hatched domestic chicks serve as an important model for experimental studies of neural and behavioral plasticity. Brain-derived neurotrophic factor (BDNF) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. Here we show ...

journal_title：Neuroreport

authors： Yamaguchi S,Aoki N,Kobayashi D,Kitajima T,Iikubo E,Katagiri S,Matsushima T,Homma KJ

更新日期：2011-12-07 00:00:00