IL-10 down-regulates human microglial IL-8 by inhibition of NF-kappaB activation.

abstract：:Both extracellular guanosine and adenosine stimulated astrocyte proliferation in vitro and increased intracellular cAMP 6-fold within 2 min. The effects of both guanosine and adenosine on proliferation and cAMP levels were inhibited by antagonists of adenosine A2 receptors but augmented by A1 receptor antagonists. The...

journal_title：Neuroreport

authors： Rathbone MP,Middlemiss PJ,DeLuca B,Jovetich M

更新日期：1991-11-01 00:00:00

abstract：:Thyroid hormones, which play an important role in the development and regeneration of the nervous system, require the presence of specific nuclear T3 receptors (NT3R). In this study we provide evidence that NT3R expression by Schwann cells was up-regulated in response to a loss of axonal contact in vitro and in vivo. ...

journal_title：Neuroreport

authors： Walter IB

更新日期：1993-11-18 00:00:00

abstract：:To compare the diagnostic value of T1-inversion recovery sequence (T1 IR) to that of a T2-sequence with contrast inversion (T2 CI) in the investigation of heterotopias. In this study, we processed a contrast-inverted copy of our coronal T2-sequence of 21 patients with subependymal and subcortical heterotopias on an on...

journal_title：Neuroreport

authors： Rösch J,Mennecke A,Knott M,Hamer HM,Doerfler A,Engelhorn T

更新日期：2020-06-07 00:00:00

abstract：:Wilson's disease (WD) is an autosomal recessive inheritance disorder of copper metabolism due to mutations in the ATP7B gene. The distribution of ATP7B gene mutations is diverse in different population. This study aimed to examine the genotypes of the ATP7B mutant alleles in WD patients from Southern China. Genomic DN...

journal_title：Neuroreport

authors： Wei Z,Huang Y,Liu A,Diao S,Yu Q,Peng Z,Hong M

更新日期：2014-10-01 00:00:00

abstract：:Homotopic and isochronic transplantation of the alar plate of the rhombomeres 7 and 8 was performed between chick and quail embryos at the stage of 10-14 somites. Analysis of the graft derivatives in 12-day-old chimeric embryos by means of the quail nucleolar marker showed that the ipsilateral inferior olive is formed...

journal_title：Neuroreport

authors： Ambrosiani J,Armengol JA,Martinez S,Puelles L

更新日期：1996-05-17 00:00:00

abstract：:Decoding verbal and nonverbal emotional expressions is an important part of speech communication. Although various studies have tried to specify the brain regions that underlie different emotions conveyed in speech, few studies have aimed to specify the time course of emotional speech decoding. We used event-related p...

journal_title：Neuroreport

authors： Paulmann S,Kotz SA

更新日期：2008-01-22 00:00:00

abstract：:Schwann cells at the somatic neuromuscular junction possess adenosine receptors that when activated by the release of endogenous transmitter modulate quantal transmitter release. Recently, purinergic receptors have been shown to exist on Schwann cells of axon varicosities in visceral smooth muscle where they are activ...

journal_title：Neuroreport

authors： Lin YQ,Bennett MR

更新日期：2006-04-03 00:00:00

abstract：:Fourteen healthy right-handed subjects were scanned using PET with a [15O]water tracer during exposure to electromagnetic field (EMF) emitted by a mobile phone and a sham-exposure under double-blind conditions. During scanning, the subjects performed a visual working memory task. Exposure to an active mobile phone pro...

journal_title：Neuroreport

authors： Haarala C,Aalto S,Hautzel H,Julkunen L,Rinne JO,Laine M,Krause B,Hämäläinen H

更新日期：2003-11-14 00:00:00

abstract：:This study demonstrates the neural system potentially involved in the representation of, and choice between, stimulus classifications in an ambiguous, novel, decision-making task. This difficult choice behaviour is taken as an example of a basic executive processing task. Subjects heard sounds that were consonant-vowe...

journal_title：Neuroreport

authors： Scott SK,Holmes A,Friston KJ,Wise RJ

更新日期：2000-05-15 00:00:00

abstract：:Human scalp EEG has demonstrated that global coherence among distant areas increases during cognitive tasks, suggesting that oscillating neural activities work to generate global neuronal assemblies for cognitive functions. The theta oscillation in a frequency range of 4-8 Hz with large amplitudes which emerges during...

journal_title：Neuroreport

authors： Mizuhara H,Wang LQ,Kobayashi K,Yamaguchi Y

更新日期：2004-06-07 00:00:00

abstract：:Sciatic nerve resection leaving a 15 mm gap could not be repaired by bridging the stumps with a silicone tube prefilled with a laminin gel. However, when purified olfactory ensheathing cells (EC) were added to the gel filling the tube, successful axonal regeneration was observed in 50% of rats. With 12 mm gaps, regene...

journal_title：Neuroreport

authors： Verdú E,Navarro X,Gudiño-Cabrera G,Rodríguez FJ,Ceballos D,Valero A,Nieto-Sampedro M

更新日期：1999-04-06 00:00:00

abstract：:Integrating information across the senses can enhance our ability to detect and classify stimuli in the environment. For example, auditory speech perception is substantially improved when the speaker's face is visible. In an fMRI study designed to investigate the neural mechanisms underlying these crossmodal behaviour...

journal_title：Neuroreport

authors： Calvert GA,Brammer MJ,Bullmore ET,Campbell R,Iversen SD,David AS

更新日期：1999-08-20 00:00:00

abstract：:The mesocorticolimbic circuit projects to the prefrontal cortex, hippocampus, amygdala, and nucleus accumbens, among others, and it originates in the dopaminergic neurons of the ventral tegmental area (VTA). The VTA receives glutamatergic inputs from the prefrontal cortex and several subcortical regions. The glutamate...

journal_title：Neuroreport

authors： Ferrada C,Sotomayor-Zárate R,Abarca J,Gysling K

更新日期：2017-01-01 00:00:00

abstract：:Synthetic beta-amyloid peptides (A betas) demonstrate lot-to-lot variation in toxicity that has not been adequately explained. Studies from our laboratory have shown that A beta toxicity may result from the ability of the peptide to promote oxidation reactions. Both A beta(1-40) and A beta(25-35) inactivate the oxidat...

journal_title：Neuroreport

authors： Hensley K,Aksenova M,Carney JM,Harris M,Butterfield DA

更新日期：1995-02-15 00:00:00

abstract：:We investigated the effect of nitric oxide (NO) on N-methyl-D-aspartate (NMDA)-induced changes in levels of dopamine (DA) and its metabolite in the striatum using in vivo microdialysis. Local administration of 1mM NMDA into the striatum significantly augmented DA release in the striatum. Simultaneous administration of...

journal_title：Neuroreport

authors： Shibata M,Araki N,Ohta K,Hamada J,Shimazu K,Fukuuchi Y

更新日期：1996-01-31 00:00:00

abstract：:The neuroprotective effects of netrin-1 after spinal cord injury and its specific molecular mechanisms have not been elucidated. In our study, Western blot, transferase UTP nick end labeling staining and immunofluorescence staining first showed that netrin-1 significantly decreased the expression levels of caspase-3, ...

journal_title：Neuroreport

authors： Gao K,Niu J,Dang X

更新日期：2020-05-07 00:00:00

abstract：:We recorded event-related potentials (ERPs) in 2-month-old infants in two different states of alertness: awake and asleep. Syllables varying in vowel duration (long vs short) were presented in an oddball paradigm, known to elicit a mismatch brain response. ERPs of both groups showed a mismatch response reflected in a ...

journal_title：Neuroreport

authors： Friederici AD,Friedrich M,Weber C

更新日期：2002-07-19 00:00:00

abstract：:When we look at our spatial environment we have the feeling that the whole visual field is coloured, yet the density of cone photoreceptors decreases considerably as eccentricity increases. We investigated colour perception (coloured/noncoloured), colour naming and whether colour helps object recognition at eccentrici...

journal_title：Neuroreport

authors： Naïli F,Despretz P,Boucart M

更新日期：2006-10-23 00:00:00

abstract：:Although prenatal stress has been repeatedly shown to inhibit adult neurogenesis in the dentate gyrus of offspring, its effects on embryonic and early postnatal brain development are not well described. Here, using the cell proliferation marker 5-bromo-2'-deoxyuridine, we examine for the first time the effect of prena...

journal_title：Neuroreport

authors： Kawamura T,Chen J,Takahashi T,Ichitani Y,Nakahara D

更新日期：2006-10-02 00:00:00

abstract：:Chronic ethanol exposure is known to alter the polyphosphoinositide (poly-PI) signaling pathway, although the exact sight of regulation is not well understood. In this study, C57B1/6J mice were given a control or an ethanol (6 g kg-1 body wt) liquid diet by gastric intubation daily for 4 weeks. Examination of levels o...

journal_title：Neuroreport

authors： Simonyi A,Zhang JP,Sun AY,Sun GY

更新日期：1996-09-02 00:00:00

abstract：:Areas of the brain's left hemisphere involved in retrieving words with emotional connotations were studied with fMRI. Participants silently generated words from different semantic categories which evoked either words with emotional connotations or emotionally neutral words. Participants repeated emotionally neutral wo...

journal_title：Neuroreport

authors： Crosson B,Radonovich K,Sadek JR,Gökçay D,Bauer RM,Fischler IS,Cato MA,Maron L,Auerbach EJ,Browd SR,Briggs RW

更新日期：1999-08-20 00:00:00

abstract：:5-[125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine ([125I]5-I-A-85380) was evaluated in the mouse as a potential in vivo imaging ligand for central nicotinic acetylcholine receptors (nAChRs). After i.v. administration of [125I]5-I-A-85380, peak brain levels of radioactivity were measured within 1 h and declined slowly ov...

journal_title：Neuroreport

authors： Vaupel DB,Mukhin AG,Kimes AS,Horti AG,Koren AO,London ED

更新日期：1998-07-13 00:00:00

abstract：:Transcranial magnetic stimulation (TMS) was applied over the frontal eye field (FEF) and the supplementary eye field (SEF) regions before execution of the first saccade in a double step task. When applied over the FEF, stimulation increased the percentage error in amplitude of the contralateral second saccade as compa...

journal_title：Neuroreport

authors： Tobler PN,Müri RM

更新日期：2002-02-11 00:00:00

abstract：:Salidroside (SDS), a phenylpropanoid glycoside isolated from Rhodiola rosea L., has been reported to be neuroprotective in vitro, which raises the possibility of using SDS as a neuroprotective agent after nerve injuries. In the present study, the possibly beneficial effect of SDS on promoting nerve regeneration after ...

journal_title：Neuroreport

authors： Sheng QS,Wang ZJ,Zhang J,Zhang YG

更新日期：2013-03-27 00:00:00

abstract：:We investigated the expression for fibroblast growth factor-2 (FGF-2), in cultured rat cerebellar granule cells and its modulation by Ca2+ regulating agents. There were no significant differences in the levels of FGF-2 mRNA in cells cultured in high vs low K+. The expression of the trophic factor is induced by Ca2+ en...

journal_title：Neuroreport

authors： Roceri M,Molteni R,Racagni G,Riva MA

更新日期：2000-11-09 00:00:00

abstract：:The present study explored duration mismatch negativity (MMN) reduction in schizophrenia. Duration MMN studies usually employ tones of very short duration (< 200 ms). For stimuli < 200 ms in duration, an increment in duration is accompanied by an increase in perceived loudness. It was previously proposed that the effe...

journal_title：Neuroreport

authors： Todd J,Michie PT,Jablensky AV

更新日期：2001-12-21 00:00:00

abstract：:Although a large amount of studies have manifested resting state electroencephalogram oscillatory abnormalities in schizophrenia and their first-degree relatives and in schizotype, the results are far from consistent and no research found any relationship between electroencephalograph (EEG) abnormalities and schizotyp...

journal_title：Neuroreport

authors： Chen C,Huang W,Chen X,Shi X,Zhu X,Ma W,Wang Y,Kang Q,Wang X,Guan M,Huang H,Wu S,Liu X

更新日期：2019-12-10 00:00:00

abstract：:Approximately 30% of patients with fatal head injuries have deposits of amyloid beta-protein (A beta); these are predominantly individuals carrying the epsilon 4 allele of apolipoprotein E (apoE). A beta deposition occurs in Alzheimer's disease (AD), for which approximately 50% of the genetic risk is attributed to apo...

journal_title：Neuroreport

authors： Zunarelli E,Nicoll JA,Graham DI

更新日期：1996-12-20 00:00:00

abstract：:The functional integrity of the 'on' and 'off' neurovisual pathways has been examined in the central visual fields of normal (n = 13), glaucomatous (n = 21) and ocular hypertensive (n = 21) individuals. The detection thresholds to light increments (onsets = bright spots) and light decrements (offsets = dark spots) on ...

journal_title：Neuroreport

authors： Mutlukan E

更新日期：1993-09-03 00:00:00

abstract：:It is known that interleukin-1beta facilitates pain, but the mechanisms of this are not understood. This study investigated the role of interleukin-1beta in the expression of Fos, a marker of neuronal activation, and hyperalgesia caused by injecting complete Freund's adjuvant into one hind paw of the rat. Interleukin-...

journal_title：Neuroreport

authors： Li A,Lao L,Wang Y,Zhang H,Ren K,Berman BM,Zhang R

更新日期：2007-03-26 00:00:00