Abstract:
:Schwann cells at the somatic neuromuscular junction possess adenosine receptors that when activated by the release of endogenous transmitter modulate quantal transmitter release. Recently, purinergic receptors have been shown to exist on Schwann cells of axon varicosities in visceral smooth muscle where they are activated by endogenous transmitters to give a calcium transient, although adenosine receptors were not identified. In the present work, we show that Schwann cells associated with axon varicosities of vascular smooth muscle, namely that of mesenteric blood vessels, possess both adenosine and purinergic receptors that when activated give rise to calcium transients in these cells. Then qualitative differences exist in the extent of adenosine and purine receptors that give rise to calcium transients in Schwann cells located in these different muscles.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Lin YQ,Bennett MRdoi
10.1097/01.wnr.0000209001.09987.77subject
Has Abstractpub_date
2006-04-03 00:00:00pages
531-5issue
5eissn
0959-4965issn
1473-558Xpii
00001756-200604030-00015journal_volume
17pub_type
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