Abstract:
:The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed before, during, and 30 min after 1 mA anodal or sham tDCS. Anodal tDCS, compared with sham stimulation, significantly improved working-memory performance. Accuracy of response was significantly increased after 20 min of tDCS application, and was further enhanced after 30 min of stimulation. This effect was maintained for 30 min after the completion of stimulation. These results suggest that tDCS at 1 mA enhances working memory in a time-dependent manner for at least 30 min in healthy participants.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Ohn SH,Park CI,Yoo WK,Ko MH,Choi KP,Kim GM,Lee YT,Kim YHdoi
10.1097/WNR.0b013e3282f2adfdsubject
Has Abstractpub_date
2008-01-08 00:00:00pages
43-7issue
1eissn
0959-4965issn
1473-558Xpii
00001756-200801080-00008journal_volume
19pub_type
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