Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers.

abstract：:Both acute and chronic exercise is consistently associated with a number of benefits to physical and mental health, including cardiovascular function, body weight, mood, and cognition. Near-infrared spectroscopy is an ideal method to measure changes in oxygenated and deoxygenated hemoglobin (O2Hb and dHb) levels in th...

journal_title：Neuroreport

authors： Giles GE,Brunyé TT,Eddy MD,Mahoney CR,Gagnon SA,Taylor HA,Kanarek RB

更新日期：2014-11-12 00:00:00

abstract：:Electroconvulsive therapy (ECT) is an appropriate clinical model to investigate blood flow during seizures. In this study cerebral blood flow velocity (CBFV) was measured during 40 ECTs in 10 patients by means of transcranial Doppler sonography. EEG was recorded continuously. Under general anesthesia, the pre-convulsi...

journal_title：Neuroreport

authors： Vollmer-Haase J,Folkerts HW,Haase CG,Deppe M,Ringelstein EB

更新日期：1998-02-16 00:00:00

abstract：:Using functional magnetic resonance imaging during word generation and spatial judgement (Landmark task), we investigated how hemispheric specializations for language and spatial processing interact in healthy individuals. We found individuals with atypical, right-hemispheric dominance for language to have more bilate...

journal_title：Neuroreport

authors： Jansen A,Flöel A,Menke R,Kanowski M,Knecht S

更新日期：2005-06-21 00:00:00

abstract：:Neuromagnetic signals evoked by synthesized syllables (/bae/ and /gae/) were recorded over the left auditory cortex of healthy humans. The fundamental frequencies of the syllables varied as if the same speaker had pronounced them at 16 different pitches. Specific mismatch responses to infrequent syllables among freque...

journal_title：Neuroreport

authors： Aulanko R,Hari R,Lounasmaa OV,Näätänen R,Sams M

更新日期：1993-09-30 00:00:00

abstract：:The effects of copper on voltage-gated A-type potassium currents were investigated in acutely dissociated rat hippocampal CA1 neurons using the whole-cell patch-clamp technique. Extracellular application of various concentrations of copper (1-1000 microM) reversibly reduced the amplitude of voltage-gated A-type potass...

journal_title：Neuroreport

authors： Niu ZD,Yu K,Gu Y,Wang M,She JQ,Chen WH,Ruan DY

更新日期：2005-09-28 00:00:00

abstract：:Neural salient serine/arginine-rich protein 1 (NSSR1) expression has been found in mouse cerebral neurons, cerebellar Purkinje cells, pyramidal neurons and granule cells of dentate gyrus and regulates the pre-mRNA splicing of genes important for neural functions. In this study, we demonstrated that NSSR1 is expressed ...

journal_title：Neuroreport

authors： Peng ZY,Lee SC,Chen XH

更新日期：2007-10-29 00:00:00

abstract：:Serotonin (5-HT) is known to reduce apoptosis and in rodent models of brain ischemia. Modulation of programmed cell death during neural development was assessed in early postnatal brains of serotonin transporter (5-HTT) knockout mice, characterized by elevated extracellular 5-HT levels. The number of apoptotic cells v...

journal_title：Neuroreport

authors： Persico AM,Baldi A,Dell'Acqua ML,Moessner R,Murphy DL,Lesch KP,Keller F

更新日期：2003-03-03 00:00:00

abstract：:The aim of the present study was to determine if both inactivating and non-inactivating potassium currents occur in skeletal muscle cells at early times in culture. Whole cell current was recorded from embryonic muscle cells within 4-10 h of plating. We found that in the cells which had an outward current, half had a ...

journal_title：Neuroreport

authors： Moody-Corbett F,Gilbert R

更新日期：1992-04-01 00:00:00

abstract：:Diabetes is often associated with impairments in brain functioning. However, the injury of specific functioning areas of the brain is not clear. To address this problem, the present study was designed to investigate possible brain functioning change in specific brain areas, particularly in areas associated with vision...

journal_title：Neuroreport

authors： Wang Z,Lu Z,Li J,Pan C,Jia Z,Chen H,Ge X

更新日期：2017-01-18 00:00:00

abstract：:Dichotic pitches and mistuned harmonics can each lead to the perception of one or two auditory objects. Comparison of event-related potentials for the perception of one versus two objects reveals an early negative and a late positive component. The relationship of these components with auditory segregation was further...

journal_title：Neuroreport

authors： Hautus MJ,Johnson BW,Colling LJ

更新日期：2009-07-01 00:00:00

abstract：:In contrast to mechanisms mediating synaptic plasticity, the pharmacological basis of perceptual learning remains to be clarified. Here we report that a specific form of perceptual learning is influenced by GABAergic mechanisms. We induced perceptual learning by Hebbian co-activation of the skin of the tip of the righ...

journal_title：Neuroreport

authors： Dinse HR,Ragert P,Pleger B,Schwenkreis P,Tegenthoff M

更新日期：2003-09-15 00:00:00

abstract：:Proteins of the postsynaptic density are implicated in mechanisms of synaptic plasticity. We examined involvement of PSD95 and alphaCaMkII in learning-dependent plastic changes of representational maps in somatosensory cortex of mice. The barrel cortex of mice was examined following a 3 day long classical conditioning...

journal_title：Neuroreport

authors： Skibinska A,Lech M,Kossut M

更新日期：2001-09-17 00:00:00

abstract：:The putative memory mechanism known as long-term potentiation (LTP) has been described in both NMDA-dependent and non-NMDA-dependent forms. The aim of the present study was to determine which of these forms described the LTP generated between perirhinal cortex (PRC) and hippocampus, two structures which have previousl...

journal_title：Neuroreport

authors： Liu P,Bilkey DK

更新日期：1996-05-17 00:00:00

abstract：:Depression is present in a large proportion of patients suffering from chronic pain, and yet the underlying mechanisms remain to be elucidated. Neuroligins (NLs), as a family of cell-adhesion proteins, are involved in synaptic formation and have been linked to various neuropsychiatric disorders. Here, we studied the a...

journal_title：Neuroreport

authors： Pan W,Zhang GF,Li HH,Ji MH,Zhou ZQ,Li KY,Yang JJ

更新日期：2018-07-04 00:00:00

abstract：:In this study, an algorithm is introduced for the automatic detection and simultaneous topographic classification of interictal regional spike activity in pediatric surface EEG records. The algorithm is based on the classification of the topographic distribution of instantaneous power by means of a 'group' trained cla...

journal_title：Neuroreport

authors： Feucht M,Hoffmann K,Steinberger K,Witte H,Benninger F,Arnold M,Doering A

更新日期：1997-07-07 00:00:00

abstract：:Nogo receptor 1 (NgR1) is the most important Nogo-A receptor. By its interaction with myelin-associated inhibitory proteins, NgR1 inhibits the regeneration of axons and is extensively expressed in the central nervous system. However, the expression of NgR1 in regenerable neurons, such as olfactory neurons, and its exp...

journal_title：Neuroreport

authors： Chen HX,Zeng XP,Sun YQ,Fu QL

更新日期：2016-07-06 00:00:00

abstract：:Statistical analysis on diffusion tensor imaging has been used extensively in mesial temporal lobe epilepsy (mTLE) and most studies report decrease in fractional anisotropy (FA) in multiple white matter regions. However, these findings vary across studies and between regions. Therefore, in this study, we used tract-ba...

journal_title：Neuroreport

authors： An J,Fang P,Wang W,Liu Z,Hu D,Qiu S

更新日期：2014-07-09 00:00:00

abstract：:Although valproate (VPA) is used widely in the treatment of bipolar mood disorder and epilepsy, the precise mechanism of action in the brain remains elusive. In this study, we investigated the effects of subchronic VPA administrations on the expression of the cyclin-dependent kinase inhibitor (Cdkn) family in the hipp...

journal_title：Neuroreport

authors： Aizawa S,Yamamuro Y

更新日期：2015-10-21 00:00:00

abstract：:Absence seizures are known to originate from disruptions within the corticothalamocortical network; however, the precise underlying cellular and molecular mechanisms that induce hypersynchronicity and hyperexcitability are debated and likely to be complex and multifactorial. Recent studies implicate impaired thalamic ...

journal_title：Neuroreport

authors： Seo S,Leitch B

更新日期：2017-12-13 00:00:00

abstract：:The seven-transmembrane receptor Smoothened is essential for hedgehog signal transduction. In adulthood, the highest density of Smoothened mRNA is found in the granule cell layer of the dentate gyrus. There, Smoothened expression is regulated by the synaptic activity involving the glutamatergic transmission. The preci...

journal_title：Neuroreport

authors： Masdeu C,Bernard V,Faure H,Traiffort E,Ruat M

更新日期：2007-03-05 00:00:00

abstract：:We have established an in-vitro coculture-system of adult rat retina with fetal midbrain explants to examine whether regenerating central nervous system axons are still able to recognize appropriate target neurons. Our results show that the retinal ganglion cell axons regenerate their axons and reinnervate the retino-...

journal_title：Neuroreport

authors： Bähr M,Eschweiler GW

更新日期：1991-10-01 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine the expression level of immunoproteasome and its clinical significance in glioma preliminarily. Furthermore, we studied the function and molecular mechanism of proteasome inhibitor ONX 0912 on glioma cell. MATERIALS AND METHODS:The expression of immunoproteasome in gli...

journal_title：Neuroreport

authors： Min L,Zeng X,Li B,Tao B,Shi J,Zhang W,Sun Q,Jing C,Wang X

更新日期：2019-10-16 00:00:00

abstract：:Caffeine is a widely self-administered psychostimulant with purported neuroprotective and procognitive effects in rodent models of aging. The cholinergic basal forebrain is important for arousal and attention and is implicated in age-related cognitive decline. Accordingly, we determined the effects of caffeine on chol...

journal_title：Neuroreport

authors： Reznikov LR,Pasumarthi RK,Fadel JR

更新日期：2009-12-09 00:00:00

abstract：:Papaverine is a non-specific vasodilatory drug, which was found to unexpectedly cause opening of the blood-brain barrier (BBB). We studied the expression of two endothelial cell related markers, endothelial barrier antigen (EBA) as a marker of BBB intactness, and matrix metalloproteinase-9 (MMP-9), an extracellular ma...

journal_title：Neuroreport

authors： Bhattacharjee AK,Kondoh T,Ikeda M,Kohmura E

更新日期：2002-12-03 00:00:00

abstract：:The amount of backward walking induced in mice by co-administration of clenbuterol, a beta-adrenoceptor agonist and putative antidepressant, and the benzodiazepine chlordiazepoxide was plotted as a three-dimensional surface, using modified Uniras software. The surface was compared with the theoretical surface to be ex...

journal_title：Neuroreport

authors： Hughes MJ,Sykes EA,Steinberg H

更新日期：1992-07-01 00:00:00

abstract：:Systemic administration of DL-fenfluramine (20 mg kg-1), an indirect serotonergic agonist, induced widespread FOS-like protein in the rat caudate putamen (CPu), paraventricular nucleus (PVn) of the hypothalamus and several intralaminar thalamic nuclei. To ascertain whether the dopaminergic nigrostriatal system coordin...

journal_title：Neuroreport

authors： Torres G

更新日期：1995-08-21 00:00:00

abstract：:Formalin fixation reduces beta-amyloid precursor protein (beta APP) immunoreactivity which restricts its study in archival tissue. Formic acid pretreatment has previously been used in an attempt to overcome this problem, but makes the sections very friable. In the present study, a microwave antigen retrieval method ha...

journal_title：Neuroreport

authors： Sherriff FE,Bridges LR,Jackson P

更新日期：1994-05-09 00:00:00

abstract：:Cell death by apoptosis occurs in mature neurones of adult rat dentate gyrus following adrenalectomy. In these studies, apoptosis in the dentate gyrus was induced 3 days after adrenalectomy in male Fischer 344 rats ranging in age from 2-3 to 24-26 months. Glial fibrillary acidic protein and transforming growth factor-...

journal_title：Neuroreport

authors： Bye N,Nichols NR

更新日期：1998-04-20 00:00:00

abstract：:Magnetoencephalography (MEG) was used to compare mismatch responses between hemispheres to changes in sound-source direction. Sixteen adults listened passively to two types of complex non-language sounds presented in separate blocks with midline standards and right- and left-lateralized deviants. Mismatch dipole ampli...

journal_title：Neuroreport

authors： Kaiser J,Lutzenberger W,Birbaumer N

更新日期：2000-09-11 00:00:00