Two classes of potassium currents in Xenopus muscle cells in young cultures.

Abstract:

:The aim of the present study was to determine if both inactivating and non-inactivating potassium currents occur in skeletal muscle cells at early times in culture. Whole cell current was recorded from embryonic muscle cells within 4-10 h of plating. We found that in the cells which had an outward current, half had a current that did not inactivate and half had a current that inactivated during a maintained depolarization (100 ms). The two groups of cells did not differ in their age in culture or resting membrane potential. The results indicate that Xenopus skeletal muscle cells can acquire both types of outward potassium current early in culture life.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Moody-Corbett F,Gilbert R

doi

10.1097/00001756-199204000-00007

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

319-22

issue

4

eissn

0959-4965

issn

1473-558X

journal_volume

3

pub_type

杂志文章
  • Neural discharge coupled to saccade offset in the cat visual cortex.

    abstract::The increase in neural activity in cat visual cortex associated with eye movements has been thought to reflect a replica of the motor command signal. We examined the timing of the saccade-related increase in neural activity in cat areas 17 and 18 in relation to saccade onset and offset. The increase in activity was te...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200006050-00013

    authors: Park J,Lee C

    更新日期:2000-06-05 00:00:00

  • Anxiolytic-like actions of anpirtoline in a mouse light-dark aversion paradigm.

    abstract::The anxiolytic-like potential of anpirtoline was assessed in a mouse light/dark aversion test. Anpirtoline (1.0 ng kg(-1)-1.0 micrograms kg-1 i.p.) reduced the aversive responding of mice. This was detected as an increase in the latency to locate the non-aversive compartment and by decreases in the percentage of the t...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199206000-00019

    authors: Metzenauer P,Barnes NM,Costall B,Gozlan H,Hamon M,Kelly ME,Murphy DA,Naylor RJ

    更新日期:1992-06-01 00:00:00

  • Benevolent sexism alters executive brain responses.

    abstract::Benevolence is widespread in our societies. It is defined as considering a subordinate group nicely but condescendingly, that is, with charity. Deleterious consequences for the target have been reported in the literature. In this experiment, we used functional MRI (fMRI) to identify whether being the target of (sexist...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283625b5b

    authors: Dardenne B,Dumont M,Sarlet M,Phillips C,Balteau E,Degueldre C,Luxen A,Salmon E,Maquet P,Collette F

    更新日期:2013-07-10 00:00:00

  • Exosomes derived from differentiated Schwann cells inhibit Schwann cell migration via microRNAs.

    abstract::Exosomes derived from Schwann cells have been known to have a variety of functions in the development and repair of the peripheral nervous system, and cyclic AMP (cAMP) is a key inducer of Schwann cell differentiation. In the present study, we aimed to study the effect of exosomes derived from differentiated Schwann c...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001435

    authors: Sohn EJ,Park HT,Shin YK

    更新日期:2020-05-07 00:00:00

  • On the origin of Alzheimer's disease: a hypothesis.

    abstract::There is no unifying hypothesis to account for the anatomical distribution of neuropathology, the involvement of beta-amyloid precursor protein (beta APP) and the role of increasing age in triggering the Alzheimer disease process. We report here that layer II pre-alpha neurones in transentorhinal and entorhinal cortex...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199301000-00001

    authors: Roberts GW,Nash M,Ince PG,Royston MC,Gentleman SM

    更新日期:1993-01-01 00:00:00

  • Cultured motor neurons possess calcium-permeable AMPA/kainate receptors.

    abstract::We examined the biology of AMPA/kainate-induced motor neuron degeneration using dissociated spinal cord cultures and motor neuron-specific antibodies which enable characterization of individual motor neurons in culture. Cobalt, which is thought to pass through Ca2+-permeable AMPA/kainate receptors following kainate ex...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199903170-00034

    authors: Bar-Peled O,O'Brien RJ,Morrison JH,Rothstein JD

    更新日期:1999-03-17 00:00:00

  • Expression of a chimeric CSF1R-LTK mediates ligand-dependent neurite outgrowth.

    abstract::In an earlier screening, we identified several genes for kinases that might control the extension of neurites. One of these genes encoded a leukocyte tyrosine kinase (LTK), which is a receptor tyrosine kinase whose ligands remain to be identified. To examine the possible role of this LTK in neurite outgrowth, we const...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283186bf8

    authors: Yamada S,Nomura T,Takano K,Fujita S,Miyake M,Miyake J

    更新日期:2008-11-19 00:00:00

  • Neurofilament-negative neurones exhibit HVA Ca2+ currents with faster inactivation kinetics.

    abstract::The whole cell configuration of the patch clamp technique was used to study the biophysical and pharmacological properties of voltage activated Ca2+ channel currents on hippocampal neurones cultured in the presence or absence of foetal calf serum. In the presence of serum cells were intensively immunostained with neur...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199504190-00008

    authors: Bertollini L,Cattaneo A,Cherubini E

    更新日期:1995-04-19 00:00:00

  • The behavioral effects of bilateral middle cerebral artery hemorrhagic ischemia in rat.

    abstract::After learning position discrimination in a T-maze water escape task, rats had either a 2 mm section of the middle cerebral artery removed bilaterally (bMCA) or they received a sham operation. Beginning on the day of surgery either total brain gangliosides (50 mg kg-1) or saline were administered daily for five days. ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199111000-00017

    authors: McDaniel WF,Fjordbak T,Schmidt MS,Tucker JC,Davis BK

    更新日期:1991-11-01 00:00:00

  • Assessing cerebral representations of short and long vowel categories by NIRS.

    abstract::The present study examined cerebral representations of Japanese long and short vowel categories with near-infrared spectroscopy (NIRS) by measuring the hemodynamic changes. Results showed that NIRS could capture phoneme-specific information. The left side of the auditory area showed large hemodynamic changes only for ...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00001756-200204160-00009

    authors: Minagawa-Kawai Y,Mori K,Furuya I,Hayashi R,Sato Y

    更新日期:2002-04-16 00:00:00

  • Semantic sentence processing reflected in the event-related potentials of one- and two-year-old children.

    abstract::The present study used the N400, an electrophysiological correlate of semantic processing, to investigate 19- and 24-month-old children's ability to integrate the meaning of words in a sentential context. Children listened passively to semantically appropriate sentences and to sentences in which the object noun violat...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000185013.98821.62

    authors: Friedrich M,Friederici AD

    更新日期:2005-11-07 00:00:00

  • Acute ethanol decreases NPY mRNA but not POMC mRNA in the arcuate nucleus.

    abstract::The acute effects of ethanol and acetaldehyde on neuropeptide mRNA expression in the arcuate nucleus (ARC) was assessed. Acetaldehyde was increased in blood following ethanol with cyanamide (a potent inhibitor of aldehyde dehydrogenase) administration. Acetaldehyde is a toxin which can cause a variety of adverse effec...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200011090-00023

    authors: Kinoshita H,Jessop DS,Finn DP,Coventry TL,Roberts DJ,Ameno K,Ijiri I,Harbuz MS

    更新日期:2000-11-09 00:00:00

  • Kinematic features of passive forelimb movements and rat cuneate neuron discharges.

    abstract::We examined the role of main and external cuneate nuclei neurons in processing sensory information during forelimb passive movement. We recorded activity of neurons using circular and figure-eight trajectories, at different speeds, in anaesthetized rats. A multivariate regression analysis was performed to correlate ne...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200203040-00004

    authors: Garifoli A,Caserta C,Bosco G,Lombardo SA,Casabona A,Perciavalle V

    更新日期:2002-03-04 00:00:00

  • The dissociation of neural circuits in a Stroop task.

    abstract::The Stroop effect refers to an increase in response time observed when the word meaning and the stimulus hue do not match. In an incongruent condition, the word 'green' is presented in the color red, whereas in a congruent condition the word 'red' is presented in the color red. To determine at what level of processing...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32832a0a10

    authors: Xiao X,Qiu J,Zhang Q

    更新日期:2009-05-06 00:00:00

  • Innervation of stem cell-derived neurons into auditory epithelia of mice.

    abstract::This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200505310-00001

    authors: Matsumoto M,Nakagawa T,Higashi T,Kim TS,Kojima K,Kita T,Sakamoto T,Ito J

    更新日期:2005-05-31 00:00:00

  • Within- and between-channel gap detection in the human auditory cortex.

    abstract::We examined the neural correlates associated with a short gap between two identical pure tones (within-channel) and between two different tones (between-channel) in an odd-ball paradigm. Gap durations were selected such that a gap between identical tones was as discriminable as a gap between two different tones. Spati...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200409150-00011

    authors: Heinrich A,Alain C,Schneider BA

    更新日期:2004-09-15 00:00:00

  • Neural correlates of the modified Stroop effect in post-traumatic stress disorder: an event-related potential study.

    abstract::Previous studies have provided electrophysiological evidence for attentional abnormalities in patients with post-traumatic stress disorder (PTSD). The present study examined the electrophysiological activity of trauma-exposed patients with or without a PTSD during a modified Stroop task. The PTSD group showed a reduce...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32835a989e

    authors: Chen X,Wei D,Dupuis-Roy N,Du X,Qiu J,Zhang Q

    更新日期:2012-12-19 00:00:00

  • Hypoxia enhances the migration and invasion of human glioblastoma U87 cells through PI3K/Akt/mTOR/HIF-1α pathway.

    abstract::Widespread invasiveness, represented by the invasion and migration, is the most important characteristic of glioblastoma multiforme (GBM) and is the main reason for therapeutic failure and recurrence of the tumor. Hypoxia is one of the main microenvironment in determining tumor invasiveness. Therefore, intense efforts...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001156

    authors: Huang W,Ding X,Ye H,Wang J,Shao J,Huang T

    更新日期:2018-12-12 00:00:00

  • Elevated adrenomedullin mRNA in lymphoblastoid cells from schizophrenic patients.

    abstract::Adrenomedullin (ADM) is a 52 amino acid peptide with multiple physiological functions and wide tissue distributions including brain. Recently, elevated plasma levels of ADM were found in patients with schizophrenia, bipolar affective disorder and autism, suggesting the involvement of ADM in the pathophysiology of ment...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000132202.69212.79

    authors: Huang CH,Chen ML,Tsai YL,Tsai MT,Chen CH

    更新日期:2004-06-28 00:00:00

  • Counter-stimulatory effects on pain perception and processing are significantly altered by attention: an fMRI study.

    abstract::Counter-stimulation reduces pain perception; however, the role of attention during this process is rarely discussed despite attention itself being a well known modulator of pain perception. This study investigated the effect of attentional modulation on pain perception during counter-stimulation using fMRI. Subjects r...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200107030-00047

    authors: Longe SE,Wise R,Bantick S,Lloyd D,Johansen-Berg H,McGlone F,Tracey I

    更新日期:2001-07-03 00:00:00

  • Voltage-activated intracellular calcium transients in thalamic relay cells and interneurons.

    abstract::The dynamics of intracellular calcium concentration ([Ca2+]i) following activation of low voltage-activated (LVA) and high voltage-activated (HVA) Ca2+ currents were studied in identified relay neurons and interneurons of the rat dorsal lateral geniculate nucleus (LGNd) in situ using Ca2+ imaging and patch-clamp techn...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199707280-00001

    authors: Munsch T,Budde T,Pape HC

    更新日期:1997-07-28 00:00:00

  • Spinal compensation for postural deficits after hemilabyrinthectomy?

    abstract::Removal of the labyrinthine organs on one side results in static and dynamic disturbances. Some functional recovery occurs over time and is paralleled in frogs by an increase in the efficacy of central vestibular pathways. Here, we report concomitant increases in dorsal root evoked ventral root responses in the brachi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:

    authors: Straka H,Kunkel A,Dieringer N

    更新日期:1993-09-01 00:00:00

  • Altered hypothalamic functional connectivity patterns in major depressive disorder.

    abstract::The hypothalamus is a limbic structure involved in the emergence and persistence of major depressive disorder symptoms. Previous studies have indicated that major depressive disorder patients exhibited dysregulation between the hypothalamus and cerebral regions. However, it is still unclear about the exact hypothalami...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001335

    authors: Wang D,Xue SW,Tan Z,Wang Y,Lian Z,Sun Y

    更新日期:2019-11-06 00:00:00

  • Calcium-dependent modulation of FGF-2 expression in cultured cerebellar granule neurons.

    abstract::We investigated the expression for fibroblast growth factor-2 (FGF-2), in cultured rat cerebellar granule cells and its modulation by Ca2+ regulating agents. There were no significant differences in the levels of FGF-2 mRNA in cells cultured in high vs low K+. The expression of the trophic factor is induced by Ca2+ en...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200011090-00043

    authors: Roceri M,Molteni R,Racagni G,Riva MA

    更新日期:2000-11-09 00:00:00

  • LTD and LTP induced by transcranial magnetic stimulation in auditory cortex.

    abstract::Using a system capable of relatively localized and rapidrate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199601310-00035

    authors: Wang H,Wang X,Scheich H

    更新日期:1996-01-31 00:00:00

  • Polyamines modulate the function of transfected glutamate receptor mGluR1a.

    abstract::Metabotropic glutamate receptor mGluR1a was expressed in human embryonic kidney 293 cells. 1S,3R-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) stimulated dose-dependently, phosphoinositide (PI) hydrolysis in transfected, but not in non-transfected cells. The polyamine spermine did not affect PI hydrolysis in th...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199306000-00059

    authors: Manev RM,Gabellini N,Manev H

    更新日期:1993-06-01 00:00:00

  • Modulation of P-CREB and expression of c-fos in cochlear nucleus and superior olive following electrical intracochlear stimulation.

    abstract::Investigating activity-dependent plasticity in the auditory brain stem of the adult rat, we observed that electrical intracochlear stimulation led to a tonotopically localized modulation of the phosphorylation of the cAMP response element binding protein (CREB) and an equally localized expression of the immediate earl...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200103260-00050

    authors: Illing RB,Michler SA

    更新日期:2001-03-26 00:00:00

  • Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease.

    abstract::Recent studies have demonstrated a loss of cannabinoid CB1 receptors in the basal ganglia in Huntington's disease (HD), but there are no data on endocannabinoid levels in this disease. In the present study, we have addressed this question by using rats with bilateral intrastriatal injections of 3-nitropropionic acid (...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200107200-00017

    authors: Lastres-Becker I,Fezza F,Cebeira M,Bisogno T,Ramos JA,Milone A,Fernández-Ruiz J,Di Marzo V

    更新日期:2001-07-20 00:00:00

  • Endogenous NGF and CNTF levels in human peripheral nerve injury.

    abstract::Nerve growth factor (NGF) is trophic to sensory and sympathetic fibres, and ciliary neurotrophic factor (CNTF) to motoneurones, in animal models of peripheral nerve injury: NGF excess produces hyperalgesia. In this first study of injured human nerves and sensory ganglia, we quantified and localized endogenous NGF and ...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-199705260-00028

    authors: Anand P,Terenghi G,Birch R,Wellmer A,Cedarbaum JM,Lindsay RM,Williams-Chestnut RE,Sinicropi DV

    更新日期:1997-05-27 00:00:00

  • Denervation impairs cutaneous microvascular function and blister healing in the rat hindlimb.

    abstract::Skin sensory nerve nocifensor functions were investigated non-invasively in rats by measuring neurogenic inflammation and blister healing-rate after unilateral hindlimb denervation. Axon reflexes were evoked by transdermal iontophoresis of acetylcholine (ACh) or noxious electrical stimulation (TNS). Sodium nitroprussi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199305000-00001

    authors: Carr RW,Delaney CA,Westerman RA,Roberts RG

    更新日期:1993-05-01 00:00:00