Polyamines modulate the function of transfected glutamate receptor mGluR1a.

abstract：:Muller glial cells of the sensory retina mediate K+ and water fluxes that are facilitated by aquaporin-4 (AQP4) water channels and by Kir4.1-K+ channels. However, it is not known which subtypes of aquaporins are expressed in the mammalian retina. Using RT-PCR, we found that both human and rat retinas express mRNA for ...

journal_title：Neuroreport

authors： Tenckhoff S,Hollborn M,Kohen L,Wolf S,Wiedemann P,Bringmann A

更新日期：2005-01-19 00:00:00

abstract：:Auditory evoked magnetic fields were recorded with a 24-SQUID magnetometer on a patient with a vascular lesion in the right auditory cortex and its vicinity. The contralateral transient 100 ms response (N100m) was absent over the damaged side, with no recovery within 16 months. Responses were normal over the healthy s...

journal_title：Neuroreport

authors： Mäkelä JP,Hari R

更新日期：1992-01-01 00:00:00

abstract：:The effects of interleukin-1beta in the paraventricular nucleus or caudal arcuate nucleus on hypertensive and tachycardiac responses induced by excitation of the central amygdaloid nucleus were studied. We observed that microinjection of sodium glutamate into central amygdaloid nucleus resulted in hypertension and tac...

journal_title：Neuroreport

authors： Lu Y,Chen W,Zou CJ

更新日期：2002-03-25 00:00:00

abstract：:The acute effects of ethanol and acetaldehyde on neuropeptide mRNA expression in the arcuate nucleus (ARC) was assessed. Acetaldehyde was increased in blood following ethanol with cyanamide (a potent inhibitor of aldehyde dehydrogenase) administration. Acetaldehyde is a toxin which can cause a variety of adverse effec...

journal_title：Neuroreport

authors： Kinoshita H,Jessop DS,Finn DP,Coventry TL,Roberts DJ,Ameno K,Ijiri I,Harbuz MS

更新日期：2000-11-09 00:00:00

abstract：:The present study used scores from Seligman's Attribution Style Questionnaire and [15O] water positron emission tomographic measurements of regional cerebral blood flow (rCBF) to investigate the relation between individual differences in dispositional pessimism and amygdala activity. During scanning 13 healthy non-sna...

journal_title：Neuroreport

authors： Fischer H,Tillfors M,Furmark T,Fredrikson M

更新日期：2001-06-13 00:00:00

abstract：:The existence of a CRF-dependent inhibition of GnRH transcription was investigated using a neuronal GnRH-expressing cell line (Gn11) stably transfected with mouse (-611 bp) or chicken (-3000 bp) GnRH promoter/luciferase reporter constructs. The presence of the CRF-R1 receptor was established using a specific CRF-R1 an...

journal_title：Neuroreport

authors： Tellam DJ,Perone MJ,Dunn IC,Radovick S,Brennand J,Rivier JE,Castro MG,Lovejoy DA

更新日期：1998-10-05 00:00:00

abstract：:The effect of thyroid hormone (TH) deficiency on the expression of neurofilament (NF) proteins and their intracellular distribution has been examined in primary cultures of neurons from embryonic rat cerebra. Northern blot analysis showed that in TH-deficient (THdef) neurons, the expression of all three NF mRNAs (NF-L...

journal_title：Neuroreport

authors： Rahaman SO,Ghosh S,Mandal SK,Sarkar PK

更新日期：2000-08-21 00:00:00

abstract：:Whereas in the mature retina the glutamate agonist 2-amino-4-phosphonobutyric acid (APB) selectively activates currents in rod bipolar and ON-cone bipolar cells, recent molecular studies have suggested the possibility of a transient appearance of the APB-sensitive receptor in developing retinal ganglion cells. In the ...

journal_title：Neuroreport

authors： Liets LC,Chalupa LM

更新日期：1996-11-25 00:00:00

abstract：:We report an event-related potential study investigating the neural basis of interference and facilitation in the picture-word interference paradigm with immediate overt naming. We used the high temporal resolution of the electrophysiological response to dissociate general and specific interference processes, by compa...

journal_title：Neuroreport

authors： Hirschfeld G,Jansma B,Bölte J,Zwitserlood P

更新日期：2008-08-06 00:00:00

abstract：:The amount of backward walking induced in mice by co-administration of clenbuterol, a beta-adrenoceptor agonist and putative antidepressant, and the benzodiazepine chlordiazepoxide was plotted as a three-dimensional surface, using modified Uniras software. The surface was compared with the theoretical surface to be ex...

journal_title：Neuroreport

authors： Hughes MJ,Sykes EA,Steinberg H

更新日期：1992-07-01 00:00:00

abstract：:The neural origins of the cortical response to rare sensory events remain poorly understood. Using simultaneous event-related potentials and magnetic resonance imaging, we investigated the anatomical profile of regional activity at various processing stages during performance of auditory and visual variants of an oddb...

journal_title：Neuroreport

authors： Rezaie R,Simos PG,Papanicolaou AC,Castillo EM,Moser DC,Passaro AD,Fletcher JM

更新日期：2011-02-16 00:00:00

abstract：:Since the characterization of orphanin FQ (OFQ), the endogenous ligand of ORL1 receptor, much work has focused on its physiological functions. OFQ was reported to antagonize the effect of opioid-induced antinociception, although its mechanism remains obscure. In the present study, whole-cell patch clamp recording tech...

journal_title：Neuroreport

authors： Zhang M,Sun QL,Wan Y,Yao L,Yu YX,Han JS

更新日期：1998-06-22 00:00:00

abstract：:To investigate the effect of the N-terminal Slit2 protein on neuronal survival and development, recombinant human N-terminal Slit2 (N-Slit2) was assayed against isolated embryonic chick dorsal root ganglion sensory, ciliary ganglion and paravertebral sympathetic neurons. N-Slit2 promoted significant levels of neuronal...

journal_title：Neuroreport

authors： Piper M,Nurcombe V,Reid K,Bartlett P,Little M

更新日期：2002-12-03 00:00:00

abstract：:This study reports on a 9-year-old girl who developed West syndrome and showed clinical features fulfilling the main revised diagnostic criteria for typical Rett syndrome (hand washing, severe cognitive impairment with absence of language, ataxic gait, progressive scoliosis and autistic features). Mutation analyses fo...

journal_title：Neuroreport

authors： Romaniello R,Saettini F,Panzeri E,Arrigoni F,Bassi MT,Borgatti R

更新日期：2015-03-25 00:00:00

abstract：:Using functional magnetic resonance imaging during word generation and spatial judgement (Landmark task), we investigated how hemispheric specializations for language and spatial processing interact in healthy individuals. We found individuals with atypical, right-hemispheric dominance for language to have more bilate...

journal_title：Neuroreport

authors： Jansen A,Flöel A,Menke R,Kanowski M,Knecht S

更新日期：2005-06-21 00:00:00

abstract：:The possible role of endogenous cholinergic innervation in hippocampal plasticity is controversial. We studied the role of acetylcholine (ACh) in short- and long-term potentiation (STP and LTP), using the cholinergic neurotoxin 192 IgG-saporin. It was still possible to induce STP the LTP in the CA1 field following com...

journal_title：Neuroreport

authors： Jouvenceau A,Billard JM,Lamour Y,Dutar P

更新日期：1996-03-22 00:00:00

abstract：:Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...

journal_title：Neuroreport

authors： Yuan J,Young BJ,Martinus RD

更新日期：2006-02-27 00:00:00

abstract：:We investigated the detection of rare task-irrelevant changes in the lexical status of speech stimuli. Participants performed a nonlinguistic task on word and pseudoword stimuli that occurred, in separate conditions, rarely or frequently. Task performance for pseudowords was deteriorated relative to words, suggesting ...

journal_title：Neuroreport

authors： Muller-Gass A,Roye A,Kirmse U,Saupe K,Jacobsen T,Schröger E

更新日期：2007-10-29 00:00:00

abstract：:Cells overexpressing the beta-amyloid precursor protein possessing a mutation found in familial Alzheimer's disease overproduce beta-amyloid peptide (A beta). Because these findings were based on immunological identification, we have chemically characterized the peptides produced. Purified A beta fragments from the co...

journal_title：Neuroreport

authors： Dovey HF,Suomensaari-Chrysler S,Lieberburg I,Sinha S,Keim PS

更新日期：1993-08-01 00:00:00

abstract：:Extracellular recordings were used to determine the effects of cannabinoids on the activity of dopamine neurons within the ventral tegmental area (VTA) and substantia nigra pars compacta (SNC). Systemic administration of the natural psychoactive cannabinoid delta 9-tetrahydrocannabinol (delta 9-THC) and the synthetic ...

journal_title：Neuroreport

authors： French ED,Dillon K,Wu X

更新日期：1997-02-10 00:00:00

abstract：:The aim was to study whether there is indication of a dissociation in processing of visuospatial and colour information in working memory in humans. Experimental subjects performed visuospatial and colour n-back tasks with and without visuospatial and colour distractive stimuli presented in the middle of the delay per...

journal_title：Neuroreport

authors： Vuontela V,Rämä P,Raninen A,Aronen HJ,Carlson S

更新日期：1999-08-02 00:00:00

abstract：:The present investigation provide evidences from a non-human primate model that naturally occurring menopause predicts a prominent signature of age-related cognitive decline. Young and aged rhesus monkeys were tested on a delayed response (DR) task known to the sensitive to aging, and reproductive status was evaluated...

journal_title：Neuroreport

authors： Roberts JA,Gilardi KV,Lasley B,Rapp PR

更新日期：1997-05-27 00:00:00

abstract：:It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this s...

journal_title：Neuroreport

authors： Hirai D,Hosokawa T,Inoue M,Miyachi S,Mikami A

更新日期：2009-04-22 00:00:00

abstract：:Adenosine has an anticonvulsant effect in various models of epilepsy. This effect appears to be mediated through the activation of adenosine A1 receptors (A1Rs). We immunohistochemically investigated the changes of A1Rs expression in kainate-treated and hippocampus-kindled rats as chronic models of epilepsy. In the no...

journal_title：Neuroreport

authors： Ochiishi T,Takita M,Ikemoto M,Nakata H,Suzuki SS

更新日期：1999-11-26 00:00:00

abstract：:Results from a computer model of a thalamic network predict that agents augmenting GABA(A)-mediated inhibition in the reticular thalamic (RE) nucleus will be antiepileptic or desynchronizing. This provides support for the hypothesis that antiepileptics like benzodiazepines may exert their effects through an isolated i...

journal_title：Neuroreport

authors： Thomas E,Lytton WW

更新日期：1998-03-09 00:00:00

abstract：:Disturbances in methyl-carbon metabolism, which result in hyperhomocysteinemia, have been associated with schizophrenia. Homozygosity for the T677 allele of the methylenetetrahydrofolate reductase (MTHFR) gene, which encodes for a thermolabile enzyme associated with hyperhomocysteinemia, has been found to be increased...

journal_title：Neuroreport

authors： Virgos C,Martorell L,Simó JM,Valero J,Figuera L,Joven J,Labad A,Vilella E

更新日期：1999-07-13 00:00:00

abstract：:Subthalamic nucleus (STN) hyperactivity follows lesions of mesencephalic dopaminergic neurons in animal models of Parkinson's disease. The mechanism leading to sustained STN hyperactivity in parkinsonism is not well understood, but it seems not to depend on the integrity of striato-pallido-subthalamic connections (the...

journal_title：Neuroreport

authors： Murer MG,Ferrario J,Delfino M,Dziewczapolski G,Gershanik OS,Raisman-Vozari R

更新日期：1999-05-14 00:00:00

abstract：:Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, how...

journal_title：Neuroreport

authors： Francl JM,Kaur G,Glass JD

更新日期：2010-11-17 00:00:00

abstract：:This study was undertaken to establish a method for the culture of organotypic spinal cord slices. A long-term organotypic spinal cord slice culture was conducted from postnatal rats. Lumbar spinal cord was isolated, and meninges were removed from the spinal cord. The spinal cord was embedded in 4% agarose, and was se...

journal_title：Neuroreport

authors： Liu JJ,Huang YJ,Xiang L,Zhao F,Huang SL

更新日期：2017-11-08 00:00:00

abstract：:Two monkeys were trained to perform wrist movements to align a pointer with visual targets. In the spatially 'compatible' condition, monkeys had to point at the target position (left/right), whereas in the 'incompatible' condition, they had to point at the position opposite to the target. A large proportion of neurone...

journal_title：Neuroreport

authors： Riehle A,Kornblum S,Requin J

更新日期：1994-12-20 00:00:00