The expression and distribution of neural salient serine/arginine-rich protein 1 in rat retina.

Abstract:

:Neural salient serine/arginine-rich protein 1 (NSSR1) expression has been found in mouse cerebral neurons, cerebellar Purkinje cells, pyramidal neurons and granule cells of dentate gyrus and regulates the pre-mRNA splicing of genes important for neural functions. In this study, we demonstrated that NSSR1 is expressed in rat retina and extensively distributed in the outer and inner plexiform layers. Double staining experiments showed that NSSR1 distributed mainly in ON-type bipolar cells and localized in the dendrites, somata and axon terminals. The result suggests that NSSR1 may play important roles in retinal function, possibly via regulating the neural-specific alternative splicing of genes.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Peng ZY,Lee SC,Chen XH

doi

10.1097/WNR.0b013e3282f0b542

subject

Has Abstract

pub_date

2007-10-29 00:00:00

pages

1641-4

issue

16

eissn

0959-4965

issn

1473-558X

pii

00001756-200710290-00002

journal_volume

18

pub_type

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