Electrophysiological evidence of encoding in self-referential effect.

abstract：:The discovery of mis-sense mutations linking the presenilin-1 (PS-1) gene on chromosome 14 to Alzheimer's disease (AD) has lead to a thorough investigation of this locus. The PS-1 gene contains a polymorphism creating two alleles. The most common allele, allele 1, has been linked with late-onset AD. Given the clinical...

journal_title：Neuroreport

authors： Singleton AB,Lamb H,Leake A,McKeith IG,Ince PG,Perry RH,Morris CM

更新日期：1997-11-10 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) and erythropoietin (EPO) are induced in brain cells after brain ischemia and show synergistic neuroprotective effects. In LN215 astrocytoma cells, IGF-1 induced the activation of hypoxia-inducible factor-1, leading to increases in EPO mRNA levels and the secretion of EPO. Interesti...

journal_title：Neuroreport

authors： Kim I,Kim CH,Yim YS,Ahn YS

更新日期：2008-11-19 00:00:00

abstract：:In Purkinje cells from cerebellar slice cultures, low-threshold Ca spike (LTS) gives rise to complex bursts in the soma that resemble the complex spike induced by climbing fibers stimulation. We show that LTS is reduced by T-type and R-type Ca channel blockers (SNX-482, nickel, or mibefradil). We propose that LTS is g...

journal_title：Neuroreport

authors： Cavelier P,Lohof AM,Lonchamp E,Beekenkamp H,Mariani J,Bossu JL

更新日期：2008-02-12 00:00:00

abstract：:The potent and selective AMPA receptor antagonist NBQX was tested for cytoprotective properties in an adult rat model of transient focal neocortical ischemia. Nineteen spontaneously hypertensive rats sustained 2 h of middle cerebral artery occlusion, followed by 22 h of recirculation. Ninety minutes following the onse...

journal_title：Neuroreport

authors： Buchan AM,Xue D,Huang ZG,Smith KH,Lesiuk H

更新日期：1991-08-01 00:00:00

abstract：:We previously reported that clusterin enhances astrocyte proliferation and extracellular signal-regulated kinase (ERK) activity. It, however, remains largely unknown how clusterin promotes cell growth. Here, we investigate the signaling pathway and related molecules underlying astrocyte proliferation by clusterin. Exo...

journal_title：Neuroreport

authors： Shim YJ,Shin YJ,Jeong SY,Kang SW,Kim BM,Park IS,Min BH

更新日期：2009-03-04 00:00:00

abstract：:There is disagreement in the literature as to whether smooth pursuit latency is reduced when a temporal gap is introduced between the extinction of a central fixation target and the illumination of an eccentric moving target. This study confirms that in human subjects smooth pursuit latency is reduced by gaps and that...

journal_title：Neuroreport

authors： Knox PC

更新日期：1998-03-30 00:00:00

abstract：:Nogo-66 receptor was first identified in neurons. Recently, it was demonstrated in glial cells as well. Our previous study on the expression of Nogo-66 receptor in the cerebellum of the rat surprisingly found its location at the glial gap junctions. Here, we present our study on Nogo-66 receptor in the rat posterior p...

journal_title：Neuroreport

authors： Wang YZ,Liu YY,Liu JP,You SW,Ju G

更新日期：2006-04-24 00:00:00

abstract：:The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile...

journal_title：Neuroreport

authors： Bourisly AK

更新日期：2016-09-28 00:00:00

abstract：:In the present study we tested the hypothesis that baclofen, a GABA-B receptor agonist, attenuates methamphetamine self-administration. Fifteen rats were trained to self-administer i.v. injections of methamphetamine (0, 0.0625, 0.125 and 0.25 mg/kg/injection) on a progressive ratio schedule of reinforcement, and then ...

journal_title：Neuroreport

authors： Ranaldi R,Poeggel K

更新日期：2002-07-02 00:00:00

abstract：:Eleven early-onset dementia families, all with affected individuals who have either presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have been confirmed to have EOFAD by autopsy, and two early onset cases with biopsy-confirmed AD pathology, were screened for missense mutations in the ...

journal_title：Neuroreport

authors： Kwok JB,Taddei K,Hallupp M,Fisher C,Brooks WS,Broe GA,Hardy J,Fulham MJ,Nicholson GA,Stell R,St George Hyslop PH,Fraser PE,Kakulas B,Clarnette R,Relkin N,Gandy SE,Schofield PR,Martins RN

更新日期：1997-04-14 00:00:00

abstract：:Although a large amount of studies have manifested resting state electroencephalogram oscillatory abnormalities in schizophrenia and their first-degree relatives and in schizotype, the results are far from consistent and no research found any relationship between electroencephalograph (EEG) abnormalities and schizotyp...

journal_title：Neuroreport

authors： Chen C,Huang W,Chen X,Shi X,Zhu X,Ma W,Wang Y,Kang Q,Wang X,Guan M,Huang H,Wu S,Liu X

更新日期：2019-12-10 00:00:00

abstract：:We have isolated a cDNA encoding an inwardly rectifying K+ channel (HH-IRK1) from human heart. The cDNA codes for a 427-amino acid protein, with two putative transmembrane domains and an H5 region. The primary structure of HH-IRK1 is homologous to that of the IRK1 channel cloned from a mouse macrophage-like cell line....

journal_title：Neuroreport

authors： Raab-Graham KF,Radeke CM,Vandenberg CA

更新日期：1994-12-20 00:00:00

abstract：:The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of all...

journal_title：Neuroreport

authors： Collier DA,Arranz MJ,Sham P,Battersby S,Vallada H,Gill P,Aitchison KJ,Sodhi M,Li T,Roberts GW,Smith B,Morton J,Murray RM,Smith D,Kirov G

更新日期：1996-07-08 00:00:00

abstract：:Cortical auditory categorization was assessed in 2-month-old infants at genetic risk for dyslexia and controls. Manipulated /bAk/ and /dAk/ speech stimuli were used as frequently presented standards. The neuroelectric brain responses of the control infants were highly sensitive to the phoneme boundary that separated t...

journal_title：Neuroreport

authors： van Leeuwen T,Been P,van Herten M,Zwarts F,Maassen B,van der Leij A

更新日期：2007-06-11 00:00:00

abstract：:Neurons respond to extracellular stimulation by modulating the expression of certain immediate-early genes. Inducible transcription factors (ITFs), such as c-Fos and Zif268, are coded by this class of gene and are among the first proteins to appear. The rapid accumulation of these products combined with histological m...

journal_title：Neuroreport

authors： Chaudhuri A

更新日期：1997-09-08 00:00:00

abstract：:There has been intense interest in determining how the visual brain processes the outside world, and in identifying the neuroanatomical correlates of the ability to create art. Comparing art production before and after illness onset permits some speculation on the function of selective brain regions affected by the ne...

journal_title：Neuroreport

authors： Kleiner-Fisman G,Lang AE

更新日期：2004-04-29 00:00:00

abstract：:Beta-N-methylamino-L-alanine (BMAA) is a nonprotein amino acid that may be involved in neurodegenerative diseases. It is produced by a large variety of cyanobacteria and is found at high levels in the brains of Alzheimer's disease and amyotrophic lateral sclerosis patients. Although BMAA is clearly a neurotoxin, previ...

journal_title：Neuroreport

authors： Liu XQ,Rush T,Ciske J,Lobner D

更新日期：2010-01-06 00:00:00

abstract：:The immediate-early genes, especially c-fos, have been suggested to have an important role in neuronal plasticity and memory. However, it has been difficult to determine if in fact c-fos can participate in control of behaviour. Here we can report that direct unilateral infusion into the rat neostriatum of an antisense...

journal_title：Neuroreport

authors： Sommer W,Bjelke B,Ganten D,Fuxe K

更新日期：1993-12-13 00:00:00

abstract：:The effect of an ischaemic focal cortical lesion on the excitability of surrounding and remote brain areas was investigated. Infarcts were produced photothrombotically in rat frontal cortex and brain excitability was assessed by a extracellular paired-pulse stimulation in coronal slices 7 days later. The cortical lesi...

journal_title：Neuroreport

authors： Buchkremer-Ratzmann I,Witte OW

更新日期：1997-01-20 00:00:00

abstract：:Statistical analysis on diffusion tensor imaging has been used extensively in mesial temporal lobe epilepsy (mTLE) and most studies report decrease in fractional anisotropy (FA) in multiple white matter regions. However, these findings vary across studies and between regions. Therefore, in this study, we used tract-ba...

journal_title：Neuroreport

authors： An J,Fang P,Wang W,Liu Z,Hu D,Qiu S

更新日期：2014-07-09 00:00:00

abstract：:Integrating information across the senses can enhance our ability to detect and classify stimuli in the environment. For example, auditory speech perception is substantially improved when the speaker's face is visible. In an fMRI study designed to investigate the neural mechanisms underlying these crossmodal behaviour...

journal_title：Neuroreport

authors： Calvert GA,Brammer MJ,Bullmore ET,Campbell R,Iversen SD,David AS

更新日期：1999-08-20 00:00:00

abstract：:Abnormal sleep architecture and white matter hyperintensities (WMHs) may be involved in cognitive impairment. There is little evidence on the connections between WMHs and chronic insomnia disorder (CID). Therefore, we evaluated the severity of WMHs and polysomnography parameters as well as cognitive tests to explore t...

journal_title：Neuroreport

authors： Lu S,Song L,Wang D,Zhang X,Lv X,Yin H,Gao Y,Liu X,Tang J

更新日期：2019-06-12 00:00:00

abstract：:The first step in olfactory transduction is the recognition of odor molecules by membrane bound receptors belonging to the superfamily of G-protein coupled receptors; other members of this family are involved in neurotransmission. Based on the considerable homology between individual members of this family, we have in...

journal_title：Neuroreport

authors： Firestein S,Shepherd GM

更新日期：1992-08-01 00:00:00

abstract：:Amyloid beta-peptide (Abeta) accumulation in aged Sprague-Dawley rats (12 months) with kaolin-induced hydrocephalus was investigated by Abeta(1-40) and Abeta(1-42) immunohistochemistry at 2, 6 and 10 weeks after induction. The low-density lipoprotein receptor-related protein-1 transporting Abeta across the blood-brain...

journal_title：Neuroreport

authors： Klinge PM,Samii A,Niescken S,Brinker T,Silverberg GD

更新日期：2006-04-24 00:00:00

abstract：:Modulation of the soleus H-reflex following galvanic vestibular stimulation (GVS) has been used to evaluate vestibulospinal tract function. It is not known whether this modulation is because of vestibular stimulation and/or cutaneous stimulation, and the suitable stimulating intensity of GVS for the modulation is not ...

journal_title：Neuroreport

authors： Okada Y,Shiozaki T,Nakamura J,Azumi Y,Inazato M,Ono M,Kondo H,Sugitani M,Matsugi A

更新日期：2018-09-05 00:00:00

abstract：:Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis. We presently evaluated neural progenitor proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus, subventricular zone, and the posterior periventricle in the brains of IL-6 knockout mice and their wild-type l...

journal_title：Neuroreport

authors： Bowen KK,Dempsey RJ,Vemuganti R

更新日期：2011-02-16 00:00:00

abstract：:The evaluative processing of the valence of action feedback is reflected by an event-related brain potential component called feedback-related negativity (FRN) or reward positivity (RewP). Recent studies have shown that FRN/RewP is markedly reduced when the action-feedback interval is long (e.g. 6000 ms), indicating t...

journal_title：Neuroreport

authors： Kimura K,Kimura M

更新日期：2016-09-28 00:00:00

abstract：:Satiety signals from the gastrointestinal tract travel via vagal afferents to the nucleus of the solitary tract (NTS) in the brain stem, the first central relay in a neural network which controls food intake. The non-competitive NMDA antagonist MK-801 facilitates food intake in rats by acting on the NTS. Here we repor...

journal_title：Neuroreport

authors： Qian M,Zhu SW,Johnson AE,Södersten P

更新日期：2000-08-21 00:00:00

abstract：:Proteins of the postsynaptic density are implicated in mechanisms of synaptic plasticity. We examined involvement of PSD95 and alphaCaMkII in learning-dependent plastic changes of representational maps in somatosensory cortex of mice. The barrel cortex of mice was examined following a 3 day long classical conditioning...

journal_title：Neuroreport

authors： Skibinska A,Lech M,Kossut M

更新日期：2001-09-17 00:00:00

abstract：:Network tools have been extensively applied to study the properties of brain functional and anatomical networks. In this paper, resiliency of Caenorhabditis elegans cortical networks against cascaded failures is studied. To this end, directed network formed by chemical connections and undirected network formed by elec...

journal_title：Neuroreport

authors： Jalili M

更新日期：2015-08-19 00:00:00