Abstract:
:Network tools have been extensively applied to study the properties of brain functional and anatomical networks. In this paper, resiliency of Caenorhabditis elegans cortical networks against cascaded failures is studied. To this end, directed network formed by chemical connections and undirected network formed by electrical couplings through gap junctions are considered. Furthermore, two types of C. elegans networks are studied: the whole cortical network of the hermaphrodite type and the network of the posterior cortex in male C. elegans. The results show that resiliency of hermaphrodite and male networks is different. The male cortical network of chemical synapses shows extensively weaker resiliency than the randomized counterparts, whereas there are some patchy differences for the gap junctions network. However, the chemical and electrical networks of hermaphrodite type show a completely different behavior. In this type, for a range of medium to large capacity parameter (load capacity of the nodes is proportional to their capacity parameter), the network of chemical connections has significantly less resiliency (P<0.001) than the randomized networks, whereas the network of gap junctions is more resilient (P<0.001) than the random ones. These results show different functionalities of chemical and electrical connections in the cortical networks of hermaphrodite C. elegans.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Jalili Mdoi
10.1097/WNR.0000000000000421subject
Has Abstractpub_date
2015-08-19 00:00:00pages
718-22issue
12eissn
0959-4965issn
1473-558Xpii
00001756-201508020-00009journal_volume
26pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Autophagy and neurogenesis play a pivotal role in maintaining cellular homeostasis of neurons in the brain. Endurance exercise (EXE) serves as a potent regulator of both autophagy and neurogenesis in the hippocampus of the brain; however, the underlying molecular mechanisms of the dual expression remains unclear. Thus...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001431
更新日期:2020-04-08 00:00:00
abstract::Previous studies in adult rats have demonstrated that the neurotrophin, brain-derived neurotrophic factor (BDNF), is present in virtually all cells of the pituitary intermediate lobe. In the present study, we demonstrate that cells cultured from adult intermediate lobe pituitary (ILP) rapidly lose their BDNF immunorea...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199703240-00005
更新日期:1997-03-24 00:00:00
abstract::Modulation of the soleus H-reflex following galvanic vestibular stimulation (GVS) has been used to evaluate vestibulospinal tract function. It is not known whether this modulation is because of vestibular stimulation and/or cutaneous stimulation, and the suitable stimulating intensity of GVS for the modulation is not ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001086
更新日期:2018-09-05 00:00:00
abstract::The temperature of the tail skin is an important factor determining tail-flick latency to noxious radiant heat in rats and mice. The temperature of the skin may also be important in determining the behavioural response in the formalin test. Morphine in low and moderate doses strongly affected the core and tail skin te...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199206000-00014
更新日期:1992-06-01 00:00:00
abstract::Neurofibromin, the product of the neurofibromatosis 1 (NF1) gene, is an important tumor suppressor protein expressed most abundantly in the nervous system. Within the central nervous system, neurofibromin has been localized to neurons and oligodendrocytes but not astrocytes. As individuals with NF1 are at an increased...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199507310-00025
更新日期:1995-07-31 00:00:00
abstract::The present study investigated the effect of lexical competition on the time course of spoken word recognition in Mandarin Chinese using a unimodal auditory priming paradigm. Two kinds of competitive environments were designed. In one session (session 1), only the unrelated and the identical primes were presented befo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000492
更新日期:2016-01-20 00:00:00
abstract::MicroRNAs (miRNAs) have been documented as critical regulators in ischemia/reperfusion-induced neuronal death. A better understanding of miRNA-mediated molecular mechanisms in ischemia/reperfusion-induced neuronal death may provide therapeutic targets for cerebral ischemia/reperfusion injury. A growing body of evidenc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001023
更新日期:2018-06-13 00:00:00
abstract::Emerging evidence has suggested that alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) protects neurons from glutamate-induced neurotoxicity. In this study, we examined the effect of AMPA on the cell surface expression of the N-methyl-D-aspartate (NMDA) receptor, a central player in glutamate-induced neurot...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283118450
更新日期:2009-01-28 00:00:00
abstract::Unilateral 6-hydroxydopamine lesion to rat substantia nigra pars compacta resulted in a modest, but significant, decrease in the specific binding of N-alpha-[methyl-3H]histamine (19 +/- 5% reduction) to synaptosomal membranes from ipsilateral striata. Dopamine synthesis was assessed in striatal slices by determining [...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200001170-00032
更新日期:2000-01-17 00:00:00
abstract::The whole-cell patch-clamp technique was employed to investigate the development of voltage-gated currents in cultured newt retinal pigment epithelial (RPE) cells. Freshly dissociated RPE cells were inexcitable and mainly exhibited a voltage-gated outward K+ current. Within a few days in culture RPE cells began to fla...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199404000-00020
更新日期:1994-04-14 00:00:00
abstract::The function of the lateral part of the human cerebellum was investigated through cerebro-cerebellar functional connectivity. We propose a laterality index method to reveal a functional and possibly anatomical pathway between the cerebral cortex and the cerebellum. The brain activity involved in learning a visually-gu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199902050-00022
更新日期:1999-02-05 00:00:00
abstract::The effects of a pharmacological blockade of the periaqueductal grey of the midbrain (PAG) on the elicitability of vocal fold movements from the facial motor cortex on the one hand and the anterior cingulate cortex and dorsomedial hypothalamus on the other were studied in the squirrel monkey. PAG blockade abolished vo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199611250-00023
更新日期:1996-11-25 00:00:00
abstract::Bilabial, alveolar and velar sounds are produced at different locations around the oral cavity. fMRI was used to localize cortical representation of articulation in seven healthy subjects during repetitive lip and vertical tongue movements as well as repetitive articulation of /pa/ (bilabial), /ta/ (alveolar), /ka/ (v...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200009110-00032
更新日期:2000-09-11 00:00:00
abstract::Slices of rat cingulate cortex, when incubated in magnesium-free medium, produce spontaneous epileptiform spikes. Here it is demonstrated that the metabotropic glutamate receptor (mGluR) agonists +/- trans-1-amino-cyclopentane-1,3-dicarboxylic acid (+/- Trans-ACPD), IS3R-ACPD and quisqualic acid (quis) can reduce the ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199210000-00024
更新日期:1992-10-01 00:00:00
abstract::Matrix metalloproteinase-9 (MMP-9) and its specific inhibitor, tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), were analysed by enzyme-linked immunosorbent assay (ELISA) and by zymography in serum and cerebrospinal fluid (CSF) of patients with amyotrophic lateral sclerosis (ALS). In contrast to patients with ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200011090-00003
更新日期:2000-11-09 00:00:00
abstract::Cyclooxygenase (COX)-2 is constitutively expressed in the superficial dorsal horn of the spinal cord, but its role in the spinal cord is still unclear. We examined the effect of intrathecally administered NS398, a selective COX-2 inhibitor and indomethacin, an non-selective COX-1 and COX-2 inhibitor, on the developmen...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199812010-00019
更新日期:1998-12-01 00:00:00
abstract::Leptin in the rat's nucleus accumbens (NAcc) core has previously shown to disrupt the effects of acute administration of cocaine on both locomotor activity and the phosphorylation levels of glycogen synthase kinase 3β. In the present study, we further measured the phosphorylation levels of GluA1 after bilateral microi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001001
更新日期:2018-04-11 00:00:00
abstract::The present paper reports how aluminium [Al(III)] at a concentration of 3.7 microM can activate the bovine erythrocytic enzyme acetylcholinesterase (AChE) by about 38% in vitro. This same activating effect was observed on AChE form human as well as from rat erythrocyte ghosts and murine neuroblastoma cells. The intera...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199409080-00023
更新日期:1994-09-08 00:00:00
abstract::The effects of huperzine A on memory impairments induced by scopolamine were evaluated using a radial maze task and inhibition of cholinesterase in vitro compared with the effects of E2020 and tacrine. Scopolamine (0.2 mg kg-1) significantly impaired spatial memory in rats. Huperzine A (0.1-0.4 mg kg-1, p.o.), E2020 (...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199612200-00020
更新日期:1996-12-20 00:00:00
abstract::Previous studies have shown that spatial memory retention is affected by the metabotropic glutamate receptor (mGluR) influencing agents (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) and trans-azetidine-2,4-dicarboxylic acid (tADA). In the present investigation we examined whether the mGluR antagonist MCPG (20 mM an...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199511270-00027
更新日期:1995-11-27 00:00:00
abstract::Learning and memory are cognitive functions commonly impaired after surgery, especially in elderly patients. Our aim was to evaluate the effect of sevoflurane anaesthesia on episodic-like memory in young and aged wild-type mice and mice with altered nicotinic cholinergic neurotransmission (beta2KO). Mice learned objec...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328330cd2b
更新日期:2009-10-28 00:00:00
abstract::Neural cells have distinct responses to CNS injury; however, neural progenitor response to CNS injury is not yet documented. Stab injury combined with injection of bromodeoxyuridine (BrdU), a thymidine analog, into adult rat cortex above the lateral ventricle for 10 min resulted in activated microglia/macrophage infil...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199908020-00012
更新日期:1999-08-02 00:00:00
abstract::Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199710200-00011
更新日期:1997-10-20 00:00:00
abstract::DJ-1, originally identified as an oncogene product, is involved in multiple processes, including cellular transformation, the oxidative stress response, and transcriptional regulation. We had previously found that DJ-1 was closely associated with the proliferation and differentiation of cultured neuronal stem cells. I...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000956
更新日期:2018-03-07 00:00:00
abstract::It is often claimed that binding information across sensory modalities leads to coherent, unitary mental representations. The dramatic illusions experienced as a result of intersensory conflict, such as the McGurk effect, are often attributed to a propensity of the perceptual system to impose multisensory coherence on...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32801776f9
更新日期:2007-03-05 00:00:00
abstract::Increased expression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) are early, critical events in several forms of apoptosis. In order to investigate the subcellular trafficking of GAPDH in vivo, the localization of a GAPDH-green fluorescent protein (GFP) fusion was studied in PC12, HEK 2...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199904060-00045
更新日期:1999-04-06 00:00:00
abstract::Intracellular recordings of activity in response to acoustic stimuli were obtained from units of the dentate nucleus of conscious cats. Twelve units with short latency responses to 70 dB clicks or hisses were injected intracellularly with biocytin and identified morphologically. The identified cells were small, relati...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199408150-00006
更新日期:1994-08-15 00:00:00
abstract::Serotonin (5-HT) is known to reduce apoptosis and in rodent models of brain ischemia. Modulation of programmed cell death during neural development was assessed in early postnatal brains of serotonin transporter (5-HTT) knockout mice, characterized by elevated extracellular 5-HT levels. The number of apoptotic cells v...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200303030-00009
更新日期:2003-03-03 00:00:00
abstract::The effects of histamine on N-methyl-d-aspartate (NMDA) receptor-mediated ion current in cultured rat cortical neurones have been investigated by superfusion of voltage-clamped (-80 mV) cells with 100 mM NMDA and with various concentrations of histamine. In a subpopulation of the neurones tested (30/53), histamine (10...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199609020-00030
更新日期:1996-09-02 00:00:00
abstract::Two monkeys were trained to perform wrist movements to align a pointer with visual targets. In the spatially 'compatible' condition, monkeys had to point at the target position (left/right), whereas in the 'incompatible' condition, they had to point at the position opposite to the target. A large proportion of neurone...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199412000-00014
更新日期:1994-12-20 00:00:00