Baclofen decreases methamphetamine self-administration in rats.

abstract：:Cyclooxygenase (COX)-2 is constitutively expressed in the superficial dorsal horn of the spinal cord, but its role in the spinal cord is still unclear. We examined the effect of intrathecally administered NS398, a selective COX-2 inhibitor and indomethacin, an non-selective COX-1 and COX-2 inhibitor, on the developmen...

journal_title：Neuroreport

authors： Yamamoto T,Sakashita Y

更新日期：1998-12-01 00:00:00

abstract：:Piccolo is one of the components of the active zone at chemical synapses and regulates the transport of synaptic vesicles. The piccolo C2A domain is an important calcium sensor and binds with phosphatidylinositol or synaptotagmin-1. Recently, clinical studies suggested that a single nucleotide polymorphism in the picc...

journal_title：Neuroreport

authors： Furukawa-Hibi Y,Nitta A,Fukumitsu H,Somiya H,Furukawa S,Nabeshima T,Yamada K

更新日期：2010-12-29 00:00:00

abstract：:Previous studies have demonstrated induced gamma-band activity (GBA) over posterior temporo-parietal and inferior frontal cortex during auditory spatial vs pattern mismatch processing, respectively. Here we investigated magnetoencephalographic oscillatory responses during an active auditory pattern oddball task. Fourt...

journal_title：Neuroreport

authors： Kaiser J,Lutzenberger W

更新日期：2004-10-05 00:00:00

abstract：:Latexin is a novel 29 kDa protein which is expressed in a subpopulation of neurones in the lateral cerebral cortex of adult rats. Here, we report the distribution of immunohistochemically detectable latexin in the rat brain during early phases of development. Latexin was first detected at embryonic day 11 (E11) along ...

journal_title：Neuroreport

authors： Takiguchi-Hayashi K,Arimatsu Y

更新日期：1995-01-26 00:00:00

abstract：:Fourteen healthy right-handed subjects were scanned using PET with a [15O]water tracer during exposure to electromagnetic field (EMF) emitted by a mobile phone and a sham-exposure under double-blind conditions. During scanning, the subjects performed a visual working memory task. Exposure to an active mobile phone pro...

journal_title：Neuroreport

authors： Haarala C,Aalto S,Hautzel H,Julkunen L,Rinne JO,Laine M,Krause B,Hämäläinen H

更新日期：2003-11-14 00:00:00

abstract：:To compare the maximum Hoffmann reflex (H-reflex) and the maximum M-wave (H : M) ratio of the H-reflex in men and women when all participants showed similar saliva levels of estradiol and progesterone. This is a cohort design study involving healthy men and women with a mean age of 22.4±3.4 years. The H : M ratio of t...

journal_title：Neuroreport

authors： Hoffman M,Norcross M,Johnson S

更新日期：2018-03-07 00:00:00

abstract：:The regional distribution of c-Fos expression in the brain after the administration of two tremorgenic agents was studied. In both the harmaline- and oxotremorin-treated rats, c-Fos-positive neurons were extensively distributed in the basal ganglia nuclei and the cerebellum. Additionally, in the harmaline-treated rats...

journal_title：Neuroreport

authors： Miwa H,Nishi K,Fuwa T,Mizuno Y

更新日期：2000-08-03 00:00:00

abstract：:Hypoxic-ischemic brain damage (HIBD) occurs due to intrauterine hypoxia ischemia influencing the energy supply for fetal brain cells, which affects the metabolism of the brain to make the brain suffer a severe damage. Erythropoietin (EPO), which regulates hemacytopoiesis, is a kind of cytokine. EPO is sensitive to hyp...

journal_title：Neuroreport

authors： Huang R,Zhang J,Ren C,Zhang X,Gu L,Dong Y,Zhang J,Zhang J

更新日期：2019-03-06 00:00:00

abstract：:Prior work has shown that kappa opioids may attenuate the effects of analgesic mu receptor agonists in some neural circuits related to pain modulation. This study examined whether hypoalgesia following exposure to a signal for shock is attenuated by infusions of the kappa agonist U69593 into the rostral ventromedial m...

journal_title：Neuroreport

authors： Foo H,Helmstetter FJ

更新日期：2000-10-20 00:00:00

abstract：:We examined effects of trial averaging upon spatial extent, spatial topography, and temporal properties of fMRI activation. Two subjects participated in an event-related visual stimulation design. There was an exponential relation between number of trials and spatial extent, such that additional trials identified, on ...

journal_title：Neuroreport

authors： Huettel SA,McCarthy G

更新日期：2001-08-08 00:00:00

abstract：:The human kallikrein gene family consists of 15 serine proteases. We examined the expression of the kallikrein genes in human cerebral cortex and hippocampus by RT-PCR and compared their expression between Alzheimer's disease (AD) and control tissue. KLK1, 4, 5, 6, 7, 8, 10, 11, 13 and 14 are expressed in both cerebra...

journal_title：Neuroreport

authors： Shimizu-Okabe C,Yousef GM,Diamandis EP,Yoshida S,Shiosaka S,Fahnestock M

更新日期：2001-08-28 00:00:00

abstract：:The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

journal_title：Neuroreport

authors： O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

更新日期：2000-11-27 00:00:00

abstract：:Integrating information across the senses can enhance our ability to detect and classify stimuli in the environment. For example, auditory speech perception is substantially improved when the speaker's face is visible. In an fMRI study designed to investigate the neural mechanisms underlying these crossmodal behaviour...

journal_title：Neuroreport

authors： Calvert GA,Brammer MJ,Bullmore ET,Campbell R,Iversen SD,David AS

更新日期：1999-08-20 00:00:00

abstract：:Astrocytes induce blood-brain barrier (BBB) properties in brain endothelial cells (EC)*O(2)*, generated in blood and EC, opens the BBB. Hence, high activity of superoxide dismutase (SOD) is a prerequisite for normal BBB function. Therefore, the influence of rat astrocytes on the expression of manganese (Mn)SOD in rat ...

journal_title：Neuroreport

authors： Schroeter ML,Müller S,Lindenau J,Wiesner B,Hanisch UK,Wolf G,Blasig IE

更新日期：2001-08-08 00:00:00

abstract：:Although accumulating evidence suggests that there are significant anatomical and histological differences between the sulci and gyri of the cerebral cortex, whether there is a difference in the distribution of interneurons between the two cortical regions remains largely unknown. In this study, we systematically comp...

journal_title：Neuroreport

authors： Gao JT,Liu Y,Gong D,Feng XM,Wan P,Luo XF,Zhu WH,Hou JC,Lv SJ

更新日期：2019-10-16 00:00:00

abstract：:Salidroside (SDS), a phenylpropanoid glycoside isolated from Rhodiola rosea L., has been reported to be neuroprotective in vitro, which raises the possibility of using SDS as a neuroprotective agent after nerve injuries. In the present study, the possibly beneficial effect of SDS on promoting nerve regeneration after ...

journal_title：Neuroreport

authors： Sheng QS,Wang ZJ,Zhang J,Zhang YG

更新日期：2013-03-27 00:00:00

abstract：:Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...

journal_title：Neuroreport

authors： Hall GB,Witelson SF,Szechtman H,Nahmias C

更新日期：2004-02-09 00:00:00

abstract：:Newly hatched domestic chicks serve as an important model for experimental studies of neural and behavioral plasticity. Brain-derived neurotrophic factor (BDNF) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. Here we show ...

journal_title：Neuroreport

authors： Yamaguchi S,Aoki N,Kobayashi D,Kitajima T,Iikubo E,Katagiri S,Matsushima T,Homma KJ

更新日期：2011-12-07 00:00:00

abstract：:Two groups of hemiparkinsonian rats received grafts of embryonic ventral mesencephalon with or without the addition of the NMDA receptor antagonist (+)dizocilpine hydrogen maleate (MK-801). When added to the cell suspension, a 10 microM concentration of MK-801 did not enhance the survival of tyrosine hydroxylase posit...

journal_title：Neuroreport

authors： Schierle GS,Karlsson J,Brundin P

更新日期：1998-05-11 00:00:00

abstract：:The hypothalamus is a limbic structure involved in the emergence and persistence of major depressive disorder symptoms. Previous studies have indicated that major depressive disorder patients exhibited dysregulation between the hypothalamus and cerebral regions. However, it is still unclear about the exact hypothalami...

journal_title：Neuroreport

authors： Wang D,Xue SW,Tan Z,Wang Y,Lian Z,Sun Y

更新日期：2019-11-06 00:00:00

abstract：:The amino acid glycine is an inhibitory neurotransmitter in the spinal cord, brain stem, and vertebrate retina. The effective synaptic concentrations of glycine are regulated by at least two transporters: glycine transporter 1 and glycine transporter 2. Here, we show retinal expression of glycine transporter 1 by in-s...

journal_title：Neuroreport

authors： Peña-Rangel MT,Riesgo-Escovar JR,Sánchez-Chávez G,Salceda R

更新日期：2008-08-27 00:00:00

abstract：:We studied the neural substrate of anticipation and learning of smooth pursuit eye movements in humans using fMRI. Both predictable and non-predictable eye movements, compared to baseline, activated a common network previously associated with oculomotor function. The temporal dynamics of activity in a subset of these ...

journal_title：Neuroreport

authors： Schmid A,Rees G,Frith C,Barnes G

更新日期：2001-05-25 00:00:00

abstract：:Matrix metalloproteinases (MMPs) may contribute to tissue damage after cerebral ischemia. In this study, wildtype and MMP-2 knockout mice were subjected to permanent and transient (2 h) occlusions of the middle cerebral artery. Gelatin zymography showed that MMP-9 levels were increased in all brains after ischemia. MM...

journal_title：Neuroreport

authors： Asahi M,Sumii T,Fini ME,Itohara S,Lo EH

更新日期：2001-09-17 00:00:00

abstract：:We have used double quantum filtered (DQF) 23Na+ nuclear magnetic resonance (NMR) spectroscopy without shift reagents in order to monitor intracellular Na+ (Na+i) in a cortical brain slice preparation. The external Na+ (Na+o) signal was reduced by 95% by the DQF sequence compared with the directly observed 23Na+. The ...

journal_title：Neuroreport

authors： Brooks KJ,Pirttilä TR,Kauppinen RA

更新日期：1993-02-01 00:00:00

abstract：:The time course of responses to repeated presentations of affective stimuli is well characterized in healthy individuals but remains to be characterized in patients with bipolar disorder. Using functional magnetic resonance imaging, we compared early-stage and late-stage brain activation during a two-block fearful fac...

journal_title：Neuroreport

authors： Killgore WD,Gruber SA,Yurgelun-Todd DA

更新日期：2008-10-08 00:00:00

abstract：:In situ hybridization was used to localize mRNA encoding two cooperative serine/threonine kinase receptors. Activin receptor IIA mRNA in the adult rat brain is highly expressed in the dentate gyrus, in the pyramidal neurones of CA3 and CA1, in the entorhinal cortex, in the cortical amygdaloid nucleus and in the amygda...

journal_title：Neuroreport

authors： Bengtsson H,Söderström S,Ebendal T

更新日期：1995-12-29 00:00:00

abstract：:Dopaminergic neurotransmission is thought to be involved in reward-related incentive learning and addictive behaviour. Amphetamine will alter glycogen synthase kinase-3β (GSK-3β) activity by increasing dopamine transporter efflux rates. We investigated the hypothesis that Wnt signalling will be altered in rat nucleus ...

journal_title：Neuroreport

authors： MacLeod RJ,Moores ME,Beninger RJ

更新日期：2012-10-03 00:00:00

abstract：:We have recently characterized a form of ex vivo depotentiation (depotentiationex vivo), which correlates tightly with fear extinction, at thalamic input synapses onto the lateral amygdala. Here, we examined the effects of learning-attenuating drugs, reported to impair fear extinction when microinjected into the basol...

journal_title：Neuroreport

authors： Kim J,Park S,Lee S,Choi S

更新日期：2009-03-25 00:00:00

abstract：:The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...

journal_title：Neuroreport

authors： Bonde C,Kristensen BW,Blaabjerg M,Johansen TE,Zimmer J,Meyer M

更新日期：2000-12-18 00:00:00

abstract：:BC200 is a long noncoding RNA expressed at high levels in the Alzheimer's disease (AD), and blocking of BC200 by siRNA is assumed to be an effective method for various disease therapy. We have established an AD cell model overexpressing amyloid β-peptide (Aβ)1-42 to observe the effects of BC200 on the cell viability a...

journal_title：Neuroreport

authors： Li H,Zheng L,Jiang A,Mo Y,Gong Q

更新日期：2018-09-05 00:00:00