Astrocytes induce manganese superoxide dismutase in brain capillary endothelial cells.

abstract：:CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

journal_title：Neuroreport

authors： Bilsland JG,Harper SJ

更新日期：2003-05-23 00:00:00

abstract：:Fourteen healthy right-handed subjects were scanned using PET with a [15O]water tracer during exposure to electromagnetic field (EMF) emitted by a mobile phone and a sham-exposure under double-blind conditions. During scanning, the subjects performed a visual working memory task. Exposure to an active mobile phone pro...

journal_title：Neuroreport

authors： Haarala C,Aalto S,Hautzel H,Julkunen L,Rinne JO,Laine M,Krause B,Hämäläinen H

更新日期：2003-11-14 00:00:00

abstract：:Low doses of estrogen (E) were given to ovariectomized (OVX) rats and the ventromedial hypothalamic nucleus (VMN) was examined at the ultrastructural level. Administration of 10 micrograms of E for two consecutive days resulted in an increase in the number of axodendritic synapses in the VMN in comparison to OVX rats ...

journal_title：Neuroreport

authors： Frankfurt M,McEwen BS

更新日期：1991-07-01 00:00:00

abstract：:Extrasynaptic transmission is mediated by the diffusion of transmitters, through the extracellular space (ECS) to receptors on neurons and glia. The three-dimensional diffusion of tetramethylammonium (mol. wt 74.1 kDa) was investigated in the isolated rat spinal cord at postnatal days 4-20. The diffusion parameters of...

journal_title：Neuroreport

authors： Prokopová S,Vargová L,Syková E

更新日期：1997-11-10 00:00:00

abstract：:In contrast to mammals, the brains of teleost fish exhibit an enormous regenerative capacity following injury. Here, we have examined the potential role of vimentin in this wound healing. Fifteen days after application of a mechanical lesion to the corpus cerebelli in the teleost fish Apteronotus leptoryhnchus, the ar...

journal_title：Neuroreport

authors： Clint SC,Zupanc GK

更新日期：2002-03-04 00:00:00

abstract：:In this study, we examined the expression of insulin-like growth factor I (IGF-I) and its receptor (IGF-IR) in dorsal root ganglia (DRG) neurons in two rodent models of nerve injury: sciatic nerve axotomy and streptozotocin-induced (STZ) painful diabetic neuropathy. We demonstrate that IGF-I and its receptor are prefe...

journal_title：Neuroreport

authors： Craner MJ,Klein JP,Black JA,Waxman SG

更新日期：2002-09-16 00:00:00

abstract：:The L1/NgCAM cell adhesion molecule is involved in neurite outgrowth, axonal fasciculation and cell migration in the nervous system. We studied the effects of antibodies against L1 injected intracranially at various times before and after training 2-day-old chicks in a visual categorization task. Memory retention was ...

journal_title：Neuroreport

authors： Tiunova A,Anokhin KV,Schachner M,Rose SP

更新日期：1998-05-11 00:00:00

abstract：:Changes in the regulation, formation, and gating of connexin-based gap junction channels occur in various disorders. It has been shown that H and Ca are involved in the regulation of gap junctional communication. Ischemia-induced intracellular acidification and Ca overload lead to closure of gap junctions and inhibit ...

journal_title：Neuroreport

authors： Kucheryavykh LY,Benedikt J,Cubano LA,Skatchkov SN,Bukauskas FF,Kucheryavykh YV

更新日期：2017-03-01 00:00:00

abstract：:The first step in olfactory transduction is the recognition of odor molecules by membrane bound receptors belonging to the superfamily of G-protein coupled receptors; other members of this family are involved in neurotransmission. Based on the considerable homology between individual members of this family, we have in...

journal_title：Neuroreport

authors： Firestein S,Shepherd GM

更新日期：1992-08-01 00:00:00

abstract：:To investigate how pheromonal information is processed in the rat accessory olfactory bulb, we optically imaged intrinsic signals to obtain high-resolution maps of activation induced by urinary stimulation. Application of volatile components in male urine mainly induced activation in the anterior accessory olfactory b...

journal_title：Neuroreport

authors： Sugai T,Yoshimura H,Kato N,Onoda N

更新日期：2006-11-06 00:00:00

abstract：:Upon perfusion with Mg2+-free artificial cerebrospinal fluid (ACSF) organotypic hippocampal slice cultures develop seizure-like events and tonic recurrent discharges in which areas CA3 and CA1 and, in contrast to acute slices, also the dentate gyrus (DG) participate. Using the fluorescent dye propidium iodide (PI) we ...

journal_title：Neuroreport

authors： Kovács R,Gutiérrez R,Kivi A,Schuchmann S,Gabriel S,Heinemann U

更新日期：1999-02-05 00:00:00

abstract：:Using a system capable of relatively localized and rapidrate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-...

journal_title：Neuroreport

authors： Wang H,Wang X,Scheich H

更新日期：1996-01-31 00:00:00

abstract：:The whole cell configuration of the patch clamp technique was used to study the biophysical and pharmacological properties of voltage activated Ca2+ channel currents on hippocampal neurones cultured in the presence or absence of foetal calf serum. In the presence of serum cells were intensively immunostained with neur...

journal_title：Neuroreport

authors： Bertollini L,Cattaneo A,Cherubini E

更新日期：1995-04-19 00:00:00

abstract：:Hyperbaric oxygen (HBO) therapy and neural stem cell (NSC) transplantation can improve traumatic brain injury (TBI) clinically. This study aimed to investigate the mechanism of HBO promoting NSC proliferation and neurological recovery after TBI. Twenty-four Sprague-Dawley rats were divided randomly into three groups: ...

journal_title：Neuroreport

authors： Yang Y,Wei H,Zhou X,Zhang F,Wang C

更新日期：2017-12-13 00:00:00

abstract：:We investigated the effects of radio frequency electromagnetic fields on brain physiology. Twenty-four healthy young men were exposed for 30 min to pulse-modulated or continuous-wave radio frequency electromagnetic fields (900 MHz; peak specific absorption rate 1 W/kg), or sham exposed. During exposure, participants p...

journal_title：Neuroreport

authors： Regel SJ,Gottselig JM,Schuderer J,Tinguely G,Rétey JV,Kuster N,Landolt HP,Achermann P

更新日期：2007-05-28 00:00:00

abstract：:The temporal lobe regions involved in memory retrieval were examined using fMRI. During an associative recognition test, participants made memory judgments about the study color of previously presented drawings of objects, and during item recognition tests they made old/new judgments about previously studied objects o...

journal_title：Neuroreport

authors： Yonelinas AP,Hopfinger JB,Buonocore MH,Kroll NE,Baynes K

更新日期：2001-02-12 00:00:00

abstract：:Recent studies of electroencephalogram event-related potentials reported aberrant feedback-related negativity (FRN) in neurological and psychiatric diseases, such as alcoholism and attention-deficit hyperactivity disorder. These diseases are characterized by high impulsivity. We investigated the relationship between F...

journal_title：Neuroreport

authors： Onoda K,Abe S,Yamaguchi S

更新日期：2010-07-14 00:00:00

abstract：:The mismatch negativity (MMN) reflects the neural representation of the acoustic environment stored in sensory memory. The short phase of sensory memory corresponds to the temporal window of integration (TWI) which integrates the neighboring sounds into a unitary event. We measured the magnetic MMN (MMNm) and the disc...

journal_title：Neuroreport

authors： Yabe H,Asai R,Hiruma T,Sutoh T,Koyama S,Kakigi R,Tervaniemi M,Kaneko S

更新日期：2004-12-22 00:00:00

abstract：:Bioelectric activity of CO2-sensitive, ventrolateral medullary neurons (VLN(CS)) in organotypic cultures from the obex level of newborn rats was tested during changes of the intracellular pH (pHi) measured in BCECF-AM loaded cultures. Hypercapnia (pCO2 80-100 mmHg) reduced pHi by 0.15 +/- 0.06 units and stimulated neu...

journal_title：Neuroreport

authors： Wiemann M,Baker RE,Bonnet U,Bingmann D

更新日期：1998-01-05 00:00:00

abstract：:Adult rats were studied for serotonin and its metabolite in basal ganglia, nociceptive responses to electric current and tremor induced by 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) to assess the effects of a single systemic injection of serotonin antiserum given at 1 day old. Antiserum-treated animals showed no over...

journal_title：Neuroreport

authors： Mohanakumar KP,Mohanty S,Ganguly DK

更新日期：1995-12-29 00:00:00

abstract：:N- and C-terminal substance P (SP) fragments increase striatal dopamine outflow at nanomolar concentrations. This contrasts with their low affinity for NK1 receptors. To explore this discrepancy, we investigated the interaction of SP and SP fragments with NK1 sites in fresh striatal slices, the same model used in the ...

journal_title：Neuroreport

authors： Michael-Titus AT,Blackburn D,Connolly Y,Priestley JV,Whelpton R

更新日期：1999-07-13 00:00:00

abstract：:The aim of the present study was to determine if both inactivating and non-inactivating potassium currents occur in skeletal muscle cells at early times in culture. Whole cell current was recorded from embryonic muscle cells within 4-10 h of plating. We found that in the cells which had an outward current, half had a ...

journal_title：Neuroreport

authors： Moody-Corbett F,Gilbert R

更新日期：1992-04-01 00:00:00

abstract：:Dysfunctional glutamate neurotransmission has been implicated in the pathophysiology of schizophrenia. Abnormal expressions in schizophrenia of ionotropic glutamate receptors (iGluRs) and the proteins that regulate their trafficking have been found to be region and subunit specific in brain, suggesting that abnormal t...

journal_title：Neuroreport

authors： Tucholski J,Simmons MS,Pinner AL,McMillan LD,Haroutunian V,Meador-Woodruff JH

更新日期：2013-08-21 00:00:00

abstract：:This study was performed to test the hypothesis that diminution in the preovulatory luteinizing hormone (LH) surge in middle-aged (MA) rats may be related to altered activity in nitric oxide (NO)ergic neurons. To begin to test the hypothesis, gene expression of hypothalamic NO synthase (NOS), the enzyme that catalyzes...

journal_title：Neuroreport

authors： Sahu A

更新日期：1998-12-21 00:00:00

abstract：:Microglia are activated by amyloid beta (Abeta) in vivo and in vitro, and Abeta-activated microglia may be involved in the pathogenesis of Alzheimer's disease (AD). We investigated the mechanism of microglial chemotaxis induced by Abeta (25-35), an active fragment of Abeta. Abeta (25-35) 0.1 and 1 nM stimulated microg...

journal_title：Neuroreport

authors： Nakai M,Hojo K,Taniguchi T,Terashima A,Kawamata T,Hashimoto T,Maeda K,Tanaka C

更新日期：1998-10-26 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：:Remote ischemic preconditioning (RIPC) is an effective regimen for neuroprotection in ischemic stroke. Exosomes are extracellular vesicles released into the blood, where they can transfer signals throughout the body. Several studies have demonstrated that RIPC leads to many changes in circulating exosomes. However, th...

journal_title：Neuroreport

authors： Li Y,Ren C,Li H,Jiang F,Wang L,Xia C,Ji X

更新日期：2019-08-14 00:00:00

abstract：:The Stroop effect refers to an increase in response time observed when the word meaning and the stimulus hue do not match. In an incongruent condition, the word 'green' is presented in the color red, whereas in a congruent condition the word 'red' is presented in the color red. To determine at what level of processing...

journal_title：Neuroreport

authors： Xiao X,Qiu J,Zhang Q

更新日期：2009-05-06 00:00:00

abstract：:The alpha 2-macroglobulin receptor/low-density lipoprotein receptor-related protein (alpha 2-M-R/LRP) is a multifunctional receptor which has been implicated in lipoprotein metabolism, clearance of proteinase-proteinase inhibitor complexes and regulation of growth factor/cytokine metabolism. This receptor is abundantl...

journal_title：Neuroreport

authors： Birkenmeier G,Grosche J,Reichenbach A

更新日期：1996-12-20 00:00:00

abstract：:We investigated the role of kainate receptor activation in modulating the influx of Ca2+ coupled to the exocytotic release of glutamate in rat hippocampal synaptosomal fractions (P2). In whole hippocampus synaptosomes stimulation with domoic acid increased the intracellular free Ca2+ concentration ([Ca2+]i) in a dose-...

journal_title：Neuroreport

authors： Malva JO,Carvalho AP,Carvalho CM

更新日期：1996-05-17 00:00:00