Absence of increased hypothalamic nitric oxide synthase gene expression during the preovulatory LH surge in middle-aged rats.

abstract：:This study examined the long-term effects of the antidepressant escitalopram on rat serotonin (5-HT) neuronal activity and hippocampal neuroplasticity. In the dorsal raphe nucleus, a 2-week treatment with escitalopram (10 mg/kg/day, subcutaneous) did not modify the firing activity of 5-HT neurons, whereas a cotreatmen...

journal_title：Neuroreport

authors： Mnie-Filali O,Faure C,Mansari ME,Lambás-Señas L,Bérod A,Zimmer L,Sánchez C,Haddjeri N

更新日期：2007-10-08 00:00:00

abstract：:The distribution of c-fos proto-oncogene expression has been studied in the periaqueductal grey matter (PAG) of non-intentional-stimulated rats by immunohistochemistry. A mean number of 53 +/- 9 Fos-like immunoreactive cells per hemiPAG, distributed into three groups, dorsolateral, lateral and ventrolateral, was found...

journal_title：Neuroreport

authors： Valverde-Navarro AA,Olucha FE,García-Verdugo JM,Hernández-Gil T,Ruiz-Torner A,Martínez-Soriano F

更新日期：1996-11-04 00:00:00

abstract：:The mismatch negativity (MMN) reflects the neural representation of the acoustic environment stored in sensory memory. The short phase of sensory memory corresponds to the temporal window of integration (TWI) which integrates the neighboring sounds into a unitary event. We measured the magnetic MMN (MMNm) and the disc...

journal_title：Neuroreport

authors： Yabe H,Asai R,Hiruma T,Sutoh T,Koyama S,Kakigi R,Tervaniemi M,Kaneko S

更新日期：2004-12-22 00:00:00

abstract：:We constructed two replication-deficient recombinant adenovirus vectors coding human basic fibroblast growth factor (bFGF), one with and one without the interleukin-2 (IL-2) secretory signal sequence and examined their neurotrophic effects on primary neuronal cells in vitro. The primary neuronal cells were successfull...

journal_title：Neuroreport

authors： Matsuoka N,Miyatake S,Yukawa H,Takahashi JC,Saiki M,Mori H,Ishii K,Akimoto M,Hamada H,Hashimoto N

更新日期：2000-06-26 00:00:00

abstract：:We examined the cortical areas showing increased activation related to axis orientation discrimination in hand movement and perception by positron emission tomography (PET) in right-handed normal human subjects while they performed a hand orientation (HO) task and an orientation discrimination (OD) task. In the OD tas...

journal_title：Neuroreport

authors： Taira M,Kawashima R,Inoue K,Fukuda H

更新日期：1998-01-26 00:00:00

abstract：:Previous event-related potential studies in Indo-European languages reported a surprising finding that failed syntactic category processing appears to block lexical-semantic integration, suggesting a functional primacy of syntax over semantics. An event-related potential experiment was conducted to test whether there ...

journal_title：Neuroreport

authors： Yu J,Zhang Y

更新日期：2008-05-07 00:00:00

abstract：:Bulbospinal C1 neurons are sympathoexcitatory and excited by substance P. However the substance P receptor (NK1 receptor), has been reported to be absent from the somata of C1 neurons. In this study, using double and triple labelling immunofluorescence and retrograde tracing, we provide evidence that the NK1 receptor ...

journal_title：Neuroreport

authors： Makeham JM,Goodchild AK,Pilowsky PM

更新日期：2001-12-04 00:00:00

abstract：:Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected nerve terminals. We al...

journal_title：Neuroreport

authors： Shuto T,Horie H,Hikawa N,Sango K,Tokashiki A,Murata H,Yamamoto I,Ishikawa Y

更新日期：2001-04-17 00:00:00

abstract：:Pharmacologically distinct NMDA-glutamate receptor subtypes have been reported in brain. We have studied the developmental expression of the mRNA encoding the NMDA receptor NR2C subunit in the rat brain by in situ hybridization. In contrast with the adult where no hybridization signal was detected in the hippocampus, ...

journal_title：Neuroreport

authors： Pollard H,Khrestchatisky M,Moreau J,Ben Ari Y

更新日期：1993-04-01 00:00:00

abstract：:The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile...

journal_title：Neuroreport

authors： Bourisly AK

更新日期：2016-09-28 00:00:00

abstract：:To test the possible role of ATP in transducing or modulating touch sensation, an isolated skin-nerve preparation from the toad, Bufo marinus, perfused on the inner side, was used to examine the effects of ATP on slowly adapting (SA) and rapidly adapting (RA) mechanoreceptors, identified by ramp and hold indentation o...

journal_title：Neuroreport

authors： Fallon JB,Maroto R,Hamill OP,Proske U

更新日期：2002-08-07 00:00:00

abstract：:Bicuculline- and baclofen-insensitive GABA receptors (GABAC receptors) on bipolar cells acutely dissociated from carp retina were investigated with using the whole-cell patch-clamp recording technique. The currents of these cells mediated by GABAC receptors showed striking desensitization, even at low concentrations o...

journal_title：Neuroreport

authors： Han MH,Li Y,Yang XL

更新日期：1997-04-14 00:00:00

abstract：:This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the time of ...

journal_title：Neuroreport

authors： Jingu H,Miura M

更新日期：1996-11-04 00:00:00

abstract：:Using reverse transcription-polymerase chain reaction and in situ hybridization, we investigated the expression and cellular localization of ciliary neurotrophic factor receptor alpha (CNTFRalpha) in the rat retina following optic nerve transection (ONT). Following ONT, a signal for CNTFRalpha mRNA appeared in a layer...

journal_title：Neuroreport

authors： Ju WK,Kim KY,Lee MY,Hofmann HD,Kirsch M,Cha JH,Oh SJ,Chun MH

更新日期：2000-11-27 00:00:00

abstract：:Recently, it has been shown that visual perception can be radically altered by signals of other modalities. For example, when a single flash is accompanied by multiple auditory beeps, it is often perceived as multiple flashes. This effect is known as the sound-induced flash illusion. In order to investigate the princi...

journal_title：Neuroreport

authors： Shams L,Ma WJ,Beierholm U

更新日期：2005-11-28 00:00:00

abstract：:Addition of the beta-hydroxy-beta-methylglutaryl-CoA (HmG-CoA) reductase inhibitor lovastatin to human HEK cells transfected with the amyloid precursor protein (APP) reduces intracellular cholesterol/protein ratios by 50%, and markedly inhibits beta-secretase cleavage of newly-synthesized APP. Exogenous water-solubili...

journal_title：Neuroreport

authors： Frears ER,Stephens DJ,Walters CE,Davies H,Austen BM

更新日期：1999-06-03 00:00:00

abstract：:In an attempt to determine whether small focal malformations of the neocortex can be visualized in vivo, focal microgyria were induced in the neocortex of otherwise normal rats by freezing injury to the developing cortical plate, and in adulthood the malformation was visualized using MRI. Induced microgyria of varying...

journal_title：Neuroreport

authors： Rosen GD,Burstein D

更新日期：1997-12-22 00:00:00

abstract：:One approach to understanding the function of presenilin 1 (PS1), is to discover those proteins with which it interacts. Evidence for a function in developmental patterning came from C. elegans, in which a PS homologue was identified by screening for suppressors of a mutation in Notch/lin-12, a gene which specifies ce...

journal_title：Neuroreport

authors： Zhou J,Liyanage U,Medina M,Ho C,Simmons AD,Lovett M,Kosik KS

更新日期：1997-04-14 00:00:00

abstract：:Static and dynamic contrast sensitivities (sCS and dCS) were evaluated before, during, immediately after and 10 min after anodal and cathodal transcranial direct current stimulation (tDCS) applied to the occipital cortex of 15 healthy subjects. Using 4 c/d spatial and 4 Hz temporal frequencies significant sCS and dCS ...

journal_title：Neuroreport

authors： Antal A,Nitsche MA,Paulus W

更新日期：2001-11-16 00:00:00

abstract：:Oculopharyngeal muscular dystrophy (OPMD) is an autosomal dominant muscular dystrophy characterized by late onset ptosis, proximal muscle weakness and swallowing difficulties. This disease has been recently linked to chromosome 14q11.2-q13 in French-Canadian pedigrees. We studied three unrelated American families with...

journal_title：Neuroreport

authors： Grewal RP,Cantor R,Turner G,Grewal RK,Detera-Wadleigh SD

更新日期：1998-04-20 00:00:00

abstract：:Positron emission tomography (PET) was used to investigate cerebral organization in seven subjects who had Mandarin Chinese as their native language (L1), and learned English (L2) later in life. When activation from word repetition was subtracted from verb generation in L1 and L2, CBF increases were observed for both ...

journal_title：Neuroreport

authors： Klein D,Milner B,Zatorre RJ,Zhao V,Nikelski J

更新日期：1999-09-09 00:00:00

abstract：:We demonstrate the use of magnetic resonance imaging (MRI) for detection of neurotransmitter stimulation using the dopamine transporter ligands amphetamine and CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane) as pharmacological challenges. We demonstrate that the unilateral loss of a hemodynamic response to eith...

journal_title：Neuroreport

authors： Chen YI,Brownell AL,Galpern W,Isacson O,Bogdanov M,Beal MF,Livni E,Rosen BR,Jenkins BG

更新日期：1999-09-29 00:00:00

abstract：:Although most neurones in the PMLS of the cat are selective for direction of motion, whether the preferred directions are organized into cortical columns, as they are in the MT area of the monkey, is not certain. We have quantitatively investigated the organization of direction selectivity of PMLS neurones. The result...

journal_title：Neuroreport

authors： Wang Y,Wang L,Li B,Wang LH,Diao YC

更新日期：1995-10-23 00:00:00

abstract：:Transplanted olfactory ensheathing cells (OECs) have previously been demonstrated to support axonal growth and myelination in the adult rat CNS. Here, the capacity of donor OECs to control the direction of axonal regeneration has been investigated following transplantation, as elongated columns, into the thalamus of a...

journal_title：Neuroreport

authors： Pérez-Bouza A,Wigley CB,Nacimiento W,Noth J,Brook GA

更新日期：1998-09-14 00:00:00

abstract：:Neuronotrophic factors (e.g. basic fibroblast growth factor, bFGF and nerve growth factor, NGF) have been demonstrated to respectively promote survival and neuritogenesis in cultures of dissociated adult rat spiral ganglia. Transforming growth factor beta (TGF beta 1) has been shown to modulate the response of culture...

journal_title：Neuroreport

authors： Lefebvre PP,Martin D,Staecker H,Weber T,Moonen G,Van de Water TR

更新日期：1992-04-01 00:00:00

abstract：:We compared beta-amyloid peptide (Abeta) levels in the serum, CSF and brain (hippocampus) and correlated these with spatial learning in APP+PS1 transgenic mice. Compared with non-transgenic littermates, male 14-month-old APP + PS1 mice were impaired in spatial learning in the water maze. Among the APP + PS1 mice, only...

journal_title：Neuroreport

authors： Liu L,Tapiola T,Herukka SK,Heikkilä M,Tanila H

更新日期：2003-01-20 00:00:00

abstract：:We studied whether pro-survival Akt was activated after transient focal cerebral ischemia and whether it inhibited pro-apoptotic Bad. Phosphorylation of Akt (serine-473) was enhanced in cortex after 1-hour ischemia, and also after 1h and 6 h of reperfusion, but it returned back to that in controls by 24 h. After this ...

journal_title：Neuroreport

authors： Friguls B,Justicia C,Pallàs M,Planas AM

更新日期：2001-10-29 00:00:00

abstract：:The neural foundation of age-related declines in prospective memory was explored using event-related brain potentials (ERPs). Consistent with previous research, a decline in the efficiency of prospective memory was observed in older adults that reflected a decrease in veridical prospective responses and an increase in...

journal_title：Neuroreport

authors： West R,Covell E

更新日期：2001-09-17 00:00:00

abstract：:To compare the effectiveness of cyclosporin-A (CsA) with methylprednisolone (MP) or a combination of both upon inhibition of lipid peroxidation (LP) after spinal cord (SC) injury, rats were treated with either CsA, MP, CSA+MP or vehicle starting 1 h after SC contusion at T9 level. LP was assessed 24h after injury by t...

journal_title：Neuroreport

authors： Diaz-Ruiz A,Rios C,Duarte I,Correa D,Guizar-Sahagun G,Grijalva I,Madrazo I,Ibarra A

更新日期：2000-06-05 00:00:00

abstract：:Event-related potentials(ERPs) were measured while subjects were constructing mental images of a letter of the alphabet. Following presentation of an uppercase letter, subjects were asked to form a mental image of the same letter in lower case, and determine whether or not it had an ascending or descending stroke (asc...

journal_title：Neuroreport

authors： Yamamoto S,Mukai H

更新日期：1998-10-26 00:00:00