Ulcerogenic cinchophen induces c-Fos expression in CRH-secreting cells in the PVH of rat brain.

abstract：:Production and differentiation of olfactory neurons occur in spherical, multi-neuronal aggregates that form in cultures where dissociated newborn rat nasal cells are plated on to CNS glial cells. We show here that neuronal cell bodies were primarily located in the peripheral layers of the spheres, and almost every neu...

journal_title：Neuroreport

authors： Pixley SK,Bage M,Miller D,Miller ML,Shi M,Hastings L

更新日期：1994-01-31 00:00:00

abstract：:Matrix metalloproteinases (MMPs) may contribute to tissue damage after cerebral ischemia. In this study, wildtype and MMP-2 knockout mice were subjected to permanent and transient (2 h) occlusions of the middle cerebral artery. Gelatin zymography showed that MMP-9 levels were increased in all brains after ischemia. MM...

journal_title：Neuroreport

authors： Asahi M,Sumii T,Fini ME,Itohara S,Lo EH

更新日期：2001-09-17 00:00:00

abstract：:We used isolated IgG antibodies selective for P2X3 receptors to study the ultrastructural distribution of these receptors in rat sensory neurons. In trigeminal ganglia, P2X3 receptor immunoreactivity occurred in small and large nerve cell bodies and their processes. Endoplasmic reticulum and Golgi apparatus were heavi...

journal_title：Neuroreport

authors： Llewellyn-Smith IJ,Burnstock G

更新日期：1998-08-03 00:00:00

abstract：:Skin sensory nerve nocifensor functions were investigated non-invasively in rats by measuring neurogenic inflammation and blister healing-rate after unilateral hindlimb denervation. Axon reflexes were evoked by transdermal iontophoresis of acetylcholine (ACh) or noxious electrical stimulation (TNS). Sodium nitroprussi...

journal_title：Neuroreport

authors： Carr RW,Delaney CA,Westerman RA,Roberts RG

更新日期：1993-05-01 00:00:00

abstract：:A two-electrode voltage clamp was used to examine the effects of the local anaesthetics (LAs) lidocaine, tetracaine and bupivacaine, and the meta-isomer of lidocaine (LL33), on the gamma-aminobutyric acid (GABA)-gated Cl- channel in the crayfish stretch receptor neurone. The voltage-induced current changes were record...

journal_title：Neuroreport

authors： Nordmark J,Rydqvist B

更新日期：1997-01-20 00:00:00

abstract：:In rapid serial visual presentation of pictures, an early event-related brain potential component shows enlarged negativity over occipital regions for emotional pictures compared with neutral pictures. The present study examined whether the processing of emotional target pictures varies as a function of stimulus repet...

journal_title：Neuroreport

authors： Schupp HT,Stockburger J,Codispoti M,Junghöfer M,Weike AI,Hamm AO

更新日期：2006-03-20 00:00:00

abstract：:This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...

journal_title：Neuroreport

authors： Zucker NL,Green S,Morris JP,Kragel P,Pelphrey KA,Bulik CM,LaBar KS

更新日期：2011-06-22 00:00:00

abstract：:The steady-state visual evoked potential (SSVEP) is a powerful tool to study basic perceptual functions in the human electroencephalogram (EEG) (e.g. selective attention). The present study aimed at finding support for the SSVEP's sensitivity to higher cognitive functions (e.g. memory). We tagged pictures of meaningle...

journal_title：Neuroreport

authors： Martens U,Gert AL,Gruber T

更新日期：2012-04-18 00:00:00

abstract：:Unilateral 6-hydroxydopamine lesion to rat substantia nigra pars compacta resulted in a modest, but significant, decrease in the specific binding of N-alpha-[methyl-3H]histamine (19 +/- 5% reduction) to synaptosomal membranes from ipsilateral striata. Dopamine synthesis was assessed in striatal slices by determining [...

journal_title：Neuroreport

authors： Molina-Hernández A,Nuñez A,Arias-Montaño JA

更新日期：2000-01-17 00:00:00

abstract：:Inherited retinal degenerations such as retinitis pigmentosa (RP) are characterized by progressive loss of photoreceptors, apparently by apoptosis, and our recent report of increased secreted Frizzled-related protein-2 (SFRP2) in RP retinas suggests altered Wnt signalling may be a component of the degenerative process...

journal_title：Neuroreport

authors： Jones SE,Jomary C,Grist J,Stewart HJ,Neal MJ

更新日期：2000-12-18 00:00:00

abstract：:The study aimed to compare the whole-brain gray matter volume (GMV) and white matter volume (WMV) difference between primary angle closure glaucoma (PACG) patients and health controls (HCs) using a voxel-based morphometry method. A total of 27 patients with PACG (17 males and 10 females) and 27 HCs (17 males and 10 fe...

journal_title：Neuroreport

authors： Jiang F,Zeng FF,Yu C,Ye YQ,Zeng XJ

更新日期：2018-11-07 00:00:00

abstract：:Upon perfusion with Mg2+-free artificial cerebrospinal fluid (ACSF) organotypic hippocampal slice cultures develop seizure-like events and tonic recurrent discharges in which areas CA3 and CA1 and, in contrast to acute slices, also the dentate gyrus (DG) participate. Using the fluorescent dye propidium iodide (PI) we ...

journal_title：Neuroreport

authors： Kovács R,Gutiérrez R,Kivi A,Schuchmann S,Gabriel S,Heinemann U

更新日期：1999-02-05 00:00:00

abstract：:We investigated the effect of nitric oxide (NO) on N-methyl-D-aspartate (NMDA)-induced changes in levels of dopamine (DA) and its metabolite in the striatum using in vivo microdialysis. Local administration of 1mM NMDA into the striatum significantly augmented DA release in the striatum. Simultaneous administration of...

journal_title：Neuroreport

authors： Shibata M,Araki N,Ohta K,Hamada J,Shimazu K,Fukuuchi Y

更新日期：1996-01-31 00:00:00

abstract：:Several neurophysiological studies have highlighted the role of the midbrain periaqueductal gray matter (PAG) in the initiation of vocalization in various animal species, from frogs to primates. With regard to humans, only two cases of complete mutism following a lesion to the PAG have been reported so far. This artic...

journal_title：Neuroreport

authors： Esposito A,Demeurisse G,Alberti B,Fabbro F

更新日期：1999-03-17 00:00:00

abstract：:We localized the gene expression of angiotensin II receptor subtypes (AT1A, AT1B, and AT2) in 2-week-old rat brain by in situ hybridization using subtype specific riboprobes. AT1A receptor mRNA but not AT1B or AT2 receptor mRNA was expressed in the subfornical organ and paraventricular nucleus of the hypothalamus. AT1...

journal_title：Neuroreport

authors： Johren O,Inagami T,Saavedra JM

更新日期：1995-12-15 00:00:00

abstract：:We investigated the protective effects of edaravone, a free radical scavenger, against ischemic damage of inner hair cells (IHCs) in gerbils. Cochlear ischemia was induced in the animals by occluding the vertebral arteries bilaterally for 15 min. Edaravone (1 mg/kg, i.v.) or saline was administered 1 h after ischemia....

journal_title：Neuroreport

authors： Maetani T,Hakuba N,Taniguchi M,Hyodo J,Shimizu Y,Gyo K

更新日期：2003-10-06 00:00:00

abstract：:The effect of huperzine A (HupA) on oxygen-glucose deprivation (OGD)-induced injury was investigated in the rat pheochromocytoma cell line PC12. OGD for 3 h and reoxygenation for 24 h triggered apoptosis characterized by chromatin condensation, nucleus fragmentation and DNA laddering. The temporal profile of c-jun, p5...

journal_title：Neuroreport

authors： Zhou J,Fu Y,Tang XC

更新日期：2001-07-20 00:00:00

abstract：:The effects of C-type natriuretic peptide (CNP) on the hypothalamo-pituitary-adrenal system response to different stressors was studied. Various doses of CNP (0.2, 2, 4 microg) were injected into the lateral cerebral ventricle of freely moving rats 30 min before stress and activation of the adrenal was measured by pla...

journal_title：Neuroreport

authors： Jászberényi M,Bujdosó E,Telegdy G

更新日期：1998-08-03 00:00:00

abstract：:Hypoxia-inducible factor-1 (HIF-1) regulates the expression of neuroprotective genes such as erythropoietin (EPO). We investigated the mechanism by which zinc, an excitotoxin-like metal, regulates HIF-1 under hypoxic conditions in astrocytes. In hypoxic LN215 cells, HIF-1alpha stabilized and accumulated in the nucleus...

journal_title：Neuroreport

authors： Kim I,Kim CH,Seo GH,Kim HS,Lee J,Kim DG,Ahn YS

更新日期：2008-07-02 00:00:00

abstract：:The aim of this study was to identify differences in structural and functional brain connectivity between poststroke mild and severe motor impairment. Twenty-four chronic stroke patients who underwent resting-state functional MRI and diffusion tensor image were retrospectively included. All patients were classified in...

journal_title：Neuroreport

authors： Lee JH,Kyeong S,Kang H,Kim DH

更新日期：2019-05-01 00:00:00

abstract：:Neurons respond to extracellular stimulation by modulating the expression of certain immediate-early genes. Inducible transcription factors (ITFs), such as c-Fos and Zif268, are coded by this class of gene and are among the first proteins to appear. The rapid accumulation of these products combined with histological m...

journal_title：Neuroreport

authors： Chaudhuri A

更新日期：1997-09-08 00:00:00

abstract：:Results from a computer model of a thalamic network predict that agents augmenting GABA(A)-mediated inhibition in the reticular thalamic (RE) nucleus will be antiepileptic or desynchronizing. This provides support for the hypothesis that antiepileptics like benzodiazepines may exert their effects through an isolated i...

journal_title：Neuroreport

authors： Thomas E,Lytton WW

更新日期：1998-03-09 00:00:00

abstract：:This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...

journal_title：Neuroreport

authors： Yan H,Zhang HY,Tang XC

更新日期：2007-05-07 00:00:00

abstract：:Cultured and transplanted adrenal medullary cells respond to ciliary neurotrophic factor (CNTF) with neurite formation and improved cell survival although the presence of the CNTF receptor-alpha (CNTFRalpha) has been unclear. This study show that CNTFRalpha mRNA was expressed in the postnatal day 1 as well as in the a...

journal_title：Neuroreport

authors： Förander P,Brené S,Strömberg I

更新日期：2000-02-28 00:00:00

abstract：:Nogo receptor 1 (NgR1) is the most important Nogo-A receptor. By its interaction with myelin-associated inhibitory proteins, NgR1 inhibits the regeneration of axons and is extensively expressed in the central nervous system. However, the expression of NgR1 in regenerable neurons, such as olfactory neurons, and its exp...

journal_title：Neuroreport

authors： Chen HX,Zeng XP,Sun YQ,Fu QL

更新日期：2016-07-06 00:00:00

abstract：:Bulbospinal C1 neurons are sympathoexcitatory and excited by substance P. However the substance P receptor (NK1 receptor), has been reported to be absent from the somata of C1 neurons. In this study, using double and triple labelling immunofluorescence and retrograde tracing, we provide evidence that the NK1 receptor ...

journal_title：Neuroreport

authors： Makeham JM,Goodchild AK,Pilowsky PM

更新日期：2001-12-04 00:00:00

abstract：:The aim of this study was to define the effects of a potent inhibitor of tyrosine phosphatases, sodium orthovanadate (0.1-100 microM for up to 48 h), on dentate gyrus cells (DGC) in culture. Treatment with 100 microM orthovanadate evoked a delayed form of cell death. To examine the possible involvement of apoptosis in...

journal_title：Neuroreport

authors： Figiel I,Kaczmarek L

更新日期：1997-07-28 00:00:00

abstract：:High K+- or caffeine-induced Ca2+ signal was studied in freshly dissociated carp retinal ON-type bipolar cells using a confocal laser-scanning microscope. In response to 35 mM K+ exposure, a rise in [Ca2+]i appeared in both the terminal and soma, but was absent after removal of external Ca2+ or in the presence of 100 ...

journal_title：Neuroreport

authors： Wu D,Zhu PH

更新日期：1999-12-16 00:00:00

abstract：:Depression is present in a large proportion of patients suffering from chronic pain, and yet the underlying mechanisms remain to be elucidated. Neuroligins (NLs), as a family of cell-adhesion proteins, are involved in synaptic formation and have been linked to various neuropsychiatric disorders. Here, we studied the a...

journal_title：Neuroreport

authors： Pan W,Zhang GF,Li HH,Ji MH,Zhou ZQ,Li KY,Yang JJ

更新日期：2018-07-04 00:00:00

abstract：:Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of cerebrovascular diseases. Using organ culture as a model for possible pathological changes we studied changes in ET(A) and ETB receptor function using a sensitive in vitro method. We observed an up-regulation of the ET(B) receptor and an ama...

journal_title：Neuroreport

authors： Hansen-Schwartz J,Edvinsson L

更新日期：2000-02-28 00:00:00