Desensitizing GABAC receptors on carp retinal bipolar cells.

abstract：:Short-term exposure of primary cultures of cerebellar granule cells from neonatal rat brain to high concentrations of glutamate results in neuronal degeneration. We found that glutamate, before causing neuronal degeneration, induced a significant increase of Tau protein immunostaining. Time-course experiments revealed...

journal_title：Neuroreport

authors： Pizzi M,Valerio A,Ribola M,Spano PF,Memo M

更新日期：1993-06-01 00:00:00

abstract：:Stop-consonant discrimination was investigated in normal-hearing listeners and cochlear-implanted patients (CIP) by recording auditory evoked potentials (AEPs) to /b epsilon/ and /p epsilon/ syllables. This study demonstrates that: (i) AEPs show time-locked components that mimic the temporal structure of the stimuli, ...

journal_title：Neuroreport

authors： Roman S,Canévet G,Lorenzi C,Triglia JM,Liégeois-Chauvel C

更新日期：2004-03-22 00:00:00

abstract：:Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg mo...

journal_title：Neuroreport

authors： Sharpe LG,Jaffe JH

更新日期：1990-09-01 00:00:00

abstract：:Human brain homogenate proteins were analyzed for binding and processing activity in relation to brain beta-amyloid precursor protein (APP). The homogenate was purified by arginine-Sepharose 4B affinity chromatography, which traps proteins with affinity to certain groups of arginine residue, such as serine proteases a...

journal_title：Neuroreport

authors： Matsumoto A,Minami M,Matsumoto R

更新日期：1997-10-20 00:00:00

abstract：:An entry of Ca2+ into postsynaptic sites may play a role in the induction of long-term potentiation (LTP) of synaptic transmission in the visual cortex. To test this hypothesis, a Ca(2+)-chelator was injected into layer II/III neurons of sliced visual cortex obtained from young rats, and excitatory postsynaptic potent...

journal_title：Neuroreport

authors： Kimura F,Tsumoto T,Nishigori A,Yoshimura Y

更新日期：1990-09-01 00:00:00

abstract：:The effect of Co-dergocrine (Hydergine) on acetylcholine (ACh) release in the striatum and hippocampus has been studied by means of brain microdialysis and compared to the effect of SKF 38393 and of LY 171555 selective D1 and D2 dopamine (DA) receptor agonists, respectively. Co-dergocrine (1 and 5 mg kg-1 i.p.) as wel...

journal_title：Neuroreport

authors： Imperato A,Obinu MC,Dazzi L,Carta G,Mascia MS,Casu MA,Gessa GL

更新日期：1994-02-24 00:00:00

abstract：:In an earlier screening, we identified several genes for kinases that might control the extension of neurites. One of these genes encoded a leukocyte tyrosine kinase (LTK), which is a receptor tyrosine kinase whose ligands remain to be identified. To examine the possible role of this LTK in neurite outgrowth, we const...

journal_title：Neuroreport

authors： Yamada S,Nomura T,Takano K,Fujita S,Miyake M,Miyake J

更新日期：2008-11-19 00:00:00

abstract：:Epilepsy is a neurological disorder with recurrent unprovoked seizures as the main symptom. Of the coumarin derivatives in Angelica gigas, decursin, a major coumarin component, was reported to exhibit significant protective activity against glutamate-induced neurotoxicity when added to primary cultures of rat cortical...

journal_title：Neuroreport

authors： Lee JK,Jeong JW,Jang T,Lee GW,Han H,Kang JS,Kim IH

更新日期：2014-11-12 00:00:00

abstract：:Brain membrane phospholipid fatty acid composition is investigated in Alzheimer's disease using fresh pathologically proven autopsy material. The most striking abnormalities in Alzheimer brains compared to age-matched controls are found in the n - 6 line of polyunsaturated fatty acids (PUFA) showing an elevation of 18...

journal_title：Neuroreport

authors： Nakada T,Kwee IL,Ellis WG

更新日期：1990-10-01 00:00:00

abstract：:The present study examined potential neuroprotective effects of HU-211, a synthetic non-psychotropic cannabinoid with non-competitive NMDA antagonist properties on neurones exposed to various excitotoxins in culture. HU-211 was found to protect neurones from NMDA and quisqualate-induced toxicity but not that produced ...

journal_title：Neuroreport

authors： Eshhar N,Striem S,Biegon A

更新日期：1993-12-13 00:00:00

abstract：:GLYX-13 (threonine-proline-proline-threonine-amide) is an amidated di-pyrrolidine that acts as a functional partial agonist at the glycine site on N-methyl-D-aspartate glutamate receptors (NMDARs). GLYX-13 can both increase NMDAR conductance at NR2B-containing receptors, and reduce conductance of non-NR2B-containing r...

journal_title：Neuroreport

authors： Stanton PK,Potter PE,Aguilar J,Decandia M,Moskal JR

更新日期：2009-08-26 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a technique for noninvasively stimulating specific cortical regions of the brain with small (<2 mA) and constant direct current on the scalp. tDCS has been widely applied, not only for medical treatment, but also for cognitive and somatosensory function enhancement, mo...

journal_title：Neuroreport

authors： Song M,Shin Y,Yun K

更新日期：2014-12-17 00:00:00

abstract：:Functional brain imaging techniques hold many promises as the methods of choice for identifying areas involved in the execution of language functions. The success of any of these techniques in fulfilling this goal depends upon their ability to produce maps of activated areas that overlap with those obtained through st...

journal_title：Neuroreport

authors： Simos PG,Breier JI,Maggio WW,Gormley WB,Zouridakis G,Willmore LJ,Wheless JW,Constantinou JE,Papanicolaou AC

更新日期：1999-01-18 00:00:00

abstract：:The effects of huperzine A on memory impairments induced by scopolamine were evaluated using a radial maze task and inhibition of cholinesterase in vitro compared with the effects of E2020 and tacrine. Scopolamine (0.2 mg kg-1) significantly impaired spatial memory in rats. Huperzine A (0.1-0.4 mg kg-1, p.o.), E2020 (...

journal_title：Neuroreport

authors： Cheng DH,Ren H,Tang XC

更新日期：1996-12-20 00:00:00

abstract：:We examined the electrophysiological correlates of the processing of social exclusion and inclusion by using a modified version of the Cyberball paradigm. Exclusion was found to be associated with a significant increase in the P3 complex. The frontal-central P3a was primarily related to the affective processing of rej...

journal_title：Neuroreport

authors： Gutz L,Küpper C,Renneberg B,Niedeggen M

更新日期：2011-06-22 00:00:00

abstract：:Positron emission tomography (PET) was used to investigate cerebral organization in seven subjects who had Mandarin Chinese as their native language (L1), and learned English (L2) later in life. When activation from word repetition was subtracted from verb generation in L1 and L2, CBF increases were observed for both ...

journal_title：Neuroreport

authors： Klein D,Milner B,Zatorre RJ,Zhao V,Nikelski J

更新日期：1999-09-09 00:00:00

abstract：:Dysfunction of the cholinergic system of the basal forebrain complex is one of the major contributors toward cognitive impairment in Alzheimer's disease (AD). In AD, degeneration of cholinergic fibers that project to the cerebral cortex and hippocampus may be attributed to the development of neurofibrillary tangles (N...

journal_title：Neuroreport

authors： Kim JM,Kim SS,Lee YD

更新日期：2015-09-09 00:00:00

abstract：:With the purpose of mapping representations of the finger and proximal arm in the human primary motor cortex (MI), we measured regional cerebral blood flow (rCBF) in eight right-handed normal volunteers during self-paced finger and proximal arm movements. Each movement activated two different fields in MI, one located...

journal_title：Neuroreport

authors： Kawashima R,Itoh H,Ono S,Satoh K,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Yanagisawa T

更新日期：1995-01-26 00:00:00

abstract：:To investigate the neural substrates for the perception of motion and of position in depth, we examined the changes in regional cerebral blood flow during positional and motion stereopsis in humans by positron emission tomography. During positional stereopsis, the right striate and peristriate cortices (areas V1/V2 an...

journal_title：Neuroreport

authors： Nagahama Y,Takayama Y,Fukuyama H,Yamauchi H,Matsuzaki S,Magata Y,Shibasaki H,Kimura J

更新日期：1996-07-29 00:00:00

abstract：:Autophagy and neurogenesis play a pivotal role in maintaining cellular homeostasis of neurons in the brain. Endurance exercise (EXE) serves as a potent regulator of both autophagy and neurogenesis in the hippocampus of the brain; however, the underlying molecular mechanisms of the dual expression remains unclear. Thus...

journal_title：Neuroreport

authors： Jang Y

更新日期：2020-04-08 00:00:00

abstract：:We investigated temporal relationships among EEG theta frequency, eye movement (EM) burst and phasic surge of arterial pressure (AP) during rapid eye movement (REM) sleep in six rats. Changes in EEG theta frequency, EM number, mean AP (MAP) and heart rate (HR) during 1 s bins were obtained with reference to the onset ...

journal_title：Neuroreport

authors： Sei H,Morita Y

更新日期：1996-11-25 00:00:00

abstract：:5-HTt1A receptor agonists reduce the neuronal release of 5-hydroxytryptamine (5-HT) by activation of raphe 5-HT1A autoreceptors. Using in vivo microdialysis in unanesthetized rats, we show that the local application of the selective 5-HT1A receptor agonist 8-OH-DPAT decreased the 5-HT output to approximately 50% of co...

journal_title：Neuroreport

authors： Casanovas JM,Hervás I,Artigas F

更新日期：1999-05-14 00:00:00

abstract：:Regional variation in the distribution of SP and NFT within the brain is well documented. Consideration of such variation is potentially of help in formulating models of disease progression. Several models propose that pathological changes in Alzheimer's disease (AD) progress in a step-wise fashion along neuronally co...

journal_title：Neuroreport

authors： Shukla C,Bridges LR

更新日期：1999-12-16 00:00:00

abstract：:Event-related potential (ERP) studies have shown that responses to illusory (IC), as compared to no contours (NC), may differ within 200 ms following stimulus presentation. However, whether these responses reflect the modulation of similar, or the activation of distinct brain regions has never been assessed. Using ERP...

journal_title：Neuroreport

authors： Pegna AJ,Khateb A,Murray MM,Landis T,Michel CM

更新日期：2002-05-24 00:00:00

abstract：:Microglial activation is a prominent feature of affected brain areas in multiple system atrophy. Microglia express proinflammatory peptides, which may be a result of activation of nuclear factor-KB. We investigated the nuclear presence of RelA, the 65 kDa subunit of the NF-KB/RelA family in striatum and brain stem of ...

journal_title：Neuroreport

authors： Schwarz SC,Seufferlein T,Liptay S,Schmid RM,Kasischke K,Foster OJ,Daniel S,Schwarz J

更新日期：1998-09-14 00:00:00

abstract：:In line with a possible role of vergence in orienting visual attention, we sought to study this eye movement in young children to provide insights on face perception. For this purpose, we measured the modulation in the angle of eye vergence in a sample of 39 children aged 6-36 months and compared it when presenting st...

journal_title：Neuroreport

authors： Esposito FL,Supèr H

更新日期：2018-02-07 00:00:00

abstract：:To investigate the origin of high-frequency somatosensory evoked potential (SEP) components, we recorded median nerve SEPs from the scalp and the depth in six monkeys. Laminar field potentials were analyzed in area 3b (N10; corresponding to human N20) and area 1 (P12; corresponding to human P25). After digital filteri...

journal_title：Neuroreport

authors： Shimazu H,Kaji R,Tsujimoto T,Kohara N,Ikeda A,Kimura J,Shibasaki H

更新日期：2000-08-21 00:00:00

abstract：:We have established an in-vitro coculture-system of adult rat retina with fetal midbrain explants to examine whether regenerating central nervous system axons are still able to recognize appropriate target neurons. Our results show that the retinal ganglion cell axons regenerate their axons and reinnervate the retino-...

journal_title：Neuroreport

authors： Bähr M,Eschweiler GW

更新日期：1991-10-01 00:00:00

abstract：:The in-vivo extracellular release of acetylcholine (ACh) from the striatum of rats was measured by intracerebral microdialysis. The ACh levels were first estimated under normoxic conditions, after which the rats were exposed to either 10% or 5% oxygen for 1 h. The average ACh content was 2.9 pmol/20 min. During hypoxi...

journal_title：Neuroreport

authors： Chleide E,Ishikawa K

更新日期：1990-11-01 00:00:00

abstract：:Regulation of CNS distribution of the human immunodeficiency virus (HIV) protease inhibitor saquinavir may involve ATP-dependent membrane-bound efflux transport proteins that are expressed in several brain cellular compartments. We recently characterized molecular and functional expression of one such transporter, mul...

journal_title：Neuroreport

authors： Dallas S,Ronaldson PT,Bendayan M,Bendayan R

更新日期：2004-05-19 00:00:00