TGF beta 1 expression is initiated in adult auditory neurons by sectioning of the auditory nerve.

abstract：:The hippocampus is the key structure for learning and memory in mammals and long-term potentiation (LTP) is an important cellular mechanism responsible for learning and memory. The influences of norepinephrine (NE) on the modulation of learning and memory, as well as LTP, through β-adrenoceptors are well documented, w...

journal_title：Neuroreport

authors： Lv J,Zhan SY,Li GX,Wang D,Li YS,Jin QH

更新日期：2016-11-09 00:00:00

abstract：:In the current study we explored the relationship between neurometabolites measured by proton magnetic resonance spectroscopy (1H-MRS) and cognitive ability assessed with a battery of neuropsychological tests. Forty-five participants were recruited from the local college community, and examined utilizing neuropsycholo...

journal_title：Neuroreport

authors： Jung RE,Yeo RA,Chiulli SJ,Sibbitt WL Jr,Weers DC,Hart BL,Brooks WM

更新日期：1999-11-08 00:00:00

abstract：:Acid-sensing ion channels (ASICs) constitute a branch of the super-gene family of amiloride-sensitive sodium channels. So far five different ASICs have been cloned from mammalian tissues. They are activated by a drop of extracellular pH but differ with respect to effective agonist concentration, desensitization and mR...

journal_title：Neuroreport

authors： Gründer S,Geissler HS,Bässler EL,Ruppersberg JP

更新日期：2000-06-05 00:00:00

abstract：:The time course of responses to repeated presentations of affective stimuli is well characterized in healthy individuals but remains to be characterized in patients with bipolar disorder. Using functional magnetic resonance imaging, we compared early-stage and late-stage brain activation during a two-block fearful fac...

journal_title：Neuroreport

authors： Killgore WD,Gruber SA,Yurgelun-Todd DA

更新日期：2008-10-08 00:00:00

abstract：:The present study aims to study sequential alterations occurring in both dopaminergic neurons and microglia in substantia nigra (SN) following intrastriatal injection of 1-methyl-4-phenylpridium ion (MPP+) in rats. Heme oxygenase-1 (HO-1), a marker of oxidative stress, first appeared in dopaminergic neurons in SN at 1...

journal_title：Neuroreport

authors： Miwa H,Kubo T,Morita S,Nakanishi I,Kondo T

更新日期：2004-04-29 00:00:00

abstract：:Prepulse inhibition (PPI) and reactivity of the acoustic startle response are widely used biobehavioral markers in psychopathology research. Previous studies have demonstrated that PPI and startle reactivity exhibit substantial within-site stability; however, between-site stability has not been established. In two sep...

journal_title：Neuroreport

authors： Cadenhead KS,Addington J,Cannon TD,Cornblatt BA,de la Fuente-Sandoval C,Mathalon DH,Perkins DO,Seidman LJ,Tsuang M,Walker EF,Woods SW,Bachman P,Belger A,Carrión RE,Donkers FC,Duncan E,Johannesen J,León-Ortiz P,Light G

更新日期：2013-08-07 00:00:00

abstract：:Monoamine oxidase A (MAOA) enzymatically degrades biogenic amines such as norepinephrine, dopamine, and serotonin, and plays a key role in the regulation of their neurotransmission. Allelic variations at the MAOA locus have been implicated in the neurobiology of aggression and impulsivity. We investigated the possible...

journal_title：Neuroreport

authors： Lee BT,Ham BJ

更新日期：2008-03-26 00:00:00

abstract：:Although most neurones in the PMLS of the cat are selective for direction of motion, whether the preferred directions are organized into cortical columns, as they are in the MT area of the monkey, is not certain. We have quantitatively investigated the organization of direction selectivity of PMLS neurones. The result...

journal_title：Neuroreport

authors： Wang Y,Wang L,Li B,Wang LH,Diao YC

更新日期：1995-10-23 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...

journal_title：Neuroreport

authors： Kyriakareli A,Cousins S,Pettorossi VE,Bronstein AM

更新日期：2013-10-02 00:00:00

abstract：:There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to the level of sentence syntax. Although birdsong can indeed have a complex structure, it lacks the combinatori...

journal_title：Neuroreport

authors： Beckers GJ,Bolhuis JJ,Okanoya K,Berwick RC

更新日期：2012-02-15 00:00:00

abstract：:delta-9-Tetrahydrocannabinol (THC) is a major psychoactive component of cannabis. We have recently localized a receptor for THC in the forebrain and found in the caudate-putamen that its gene expression is modulated by glucocorticoids, dopamine and glutamate. Here, we report for the first time, using quantitative in s...

journal_title：Neuroreport

authors： Mailleux P,Verslype M,Preud'homme X,Vanderhaeghen JJ

更新日期：1994-06-02 00:00:00

abstract：:Approximately 30% of patients with fatal head injuries have deposits of amyloid beta-protein (A beta); these are predominantly individuals carrying the epsilon 4 allele of apolipoprotein E (apoE). A beta deposition occurs in Alzheimer's disease (AD), for which approximately 50% of the genetic risk is attributed to apo...

journal_title：Neuroreport

authors： Zunarelli E,Nicoll JA,Graham DI

更新日期：1996-12-20 00:00:00

abstract：:Neural progenitor/stem cells reside in the subventricular zone and dentate gyrus of the adult rat brain, which proliferate in response to several growth factors. Here we show that the neurospheres generated from the adult dentate gyrus and subventricular zone proliferate in vitro in response to fibroblast growth facto...

journal_title：Neuroreport

authors： Kalluri HS,Vemuganti R,Dempsey RJ

更新日期：2005-05-31 00:00:00

abstract：:Astrocytes induce blood-brain barrier (BBB) properties in brain endothelial cells (EC)*O(2)*, generated in blood and EC, opens the BBB. Hence, high activity of superoxide dismutase (SOD) is a prerequisite for normal BBB function. Therefore, the influence of rat astrocytes on the expression of manganese (Mn)SOD in rat ...

journal_title：Neuroreport

authors： Schroeter ML,Müller S,Lindenau J,Wiesner B,Hanisch UK,Wolf G,Blasig IE

更新日期：2001-08-08 00:00:00

abstract：:TECTA and DFNA5 are the mouse orthologues of the human deafness-associated genes TECTA and DFNA5. To determine how expression of these genes is regulated during development, relative mRNA abundance was examined in mice by non-radioactive RT-PCR. TECTA mRNA was detected on embryonic day 15 (E15), increased to its highe...

journal_title：Neuroreport

authors： Maeda Y,Fukushima K,Kasai N,Maeta M,Nishizaki K

更新日期：2001-10-29 00:00:00

abstract：:Recently it has been reported that a missense G(88)C mutation within exon 3 and a missense G(209)A mutation within exon 4 of the alpha-synuclein gene were linked to familial Parkinson's Disease (PD). We decided to investigate if these and any other mutations in exons 3 and 4 of the alpha-synuclein gene could be detect...

journal_title：Neuroreport

authors： El-Agnaf OM,Curran MD,Wallace A,Middleton D,Murgatroyd C,Curtis A,Perry R,Jaros E

更新日期：1998-12-01 00:00:00

abstract：:The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...

journal_title：Neuroreport

authors： Bonde C,Kristensen BW,Blaabjerg M,Johansen TE,Zimmer J,Meyer M

更新日期：2000-12-18 00:00:00

abstract：:The distribution of histamine H1, H3, dopamine D1 and D2 receptors in the brain was studied by receptor autoradiography using a high-sensitivity and high-resolution imaging plate system. [3H]Pyrilamine, [3H](R)alpha-methyl-histamine, [11C]SCH23390, and [11C]N-methylspiperone (or [11C]YM-09151-2) were used as ligands t...

journal_title：Neuroreport

authors： Yanai K,Ryu JH,Watanabe T,Iwata R,Ido T

更新日期：1992-11-01 00:00:00

abstract：:Optical imaging of rat barrel cortex has provided detailed spatio-temporal maps of functional cortical architecture. We describe an event-related procedure (ERP) for optical imaging based on selective signal averaging as reported by Burock et al., using an anti-correlative pseudo-random event sequence. The sequence us...

journal_title：Neuroreport

authors： Martindale J,Berwick J,Johnston D,Jones M,Zheng Y,Coffey P,Paley M,Mayhew J

更新日期：2000-07-14 00:00:00

abstract：:NONINVASIVE photolytic injury to targeted neuronal subpopulations in vivo causes unique, slowly progressive neuronal degeneration. To examine the mechanisms of degeneration toward development and transplantation studies, cytosolic calcium levels were measured in vitro from neocortical neurons after incorporation of ph...

journal_title：Neuroreport

authors： Sheen VL,Dreyer EB,Macklis JD

更新日期：1992-08-01 00:00:00

abstract：:The effects of copper on voltage-gated A-type potassium currents were investigated in acutely dissociated rat hippocampal CA1 neurons using the whole-cell patch-clamp technique. Extracellular application of various concentrations of copper (1-1000 microM) reversibly reduced the amplitude of voltage-gated A-type potass...

journal_title：Neuroreport

authors： Niu ZD,Yu K,Gu Y,Wang M,She JQ,Chen WH,Ruan DY

更新日期：2005-09-28 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:Tau protein phosphorylation has been implicated as a main process that regulates microtubule dynamics. A large number of tau isoforms is generated by phosphorylation through the action of a diversity of kinases. We have analysed variations in tau phosphorylation by two-dimensional gel electrophoresis, where a great he...

journal_title：Neuroreport

authors： Araujo HM,Sutton R,Moura Neto V

更新日期：1994-10-27 00:00:00

abstract：:The present study used scores from Seligman's Attribution Style Questionnaire and [15O] water positron emission tomographic measurements of regional cerebral blood flow (rCBF) to investigate the relation between individual differences in dispositional pessimism and amygdala activity. During scanning 13 healthy non-sna...

journal_title：Neuroreport

authors： Fischer H,Tillfors M,Furmark T,Fredrikson M

更新日期：2001-06-13 00:00:00

abstract：:Chronic nicotine exposure enhances axon reflexes in adult rats. Since smoking mothers expose their infants to nicotine, this study investigated whether late gestational and or lactational maternal nicotine exposure affects neonatal axon reflexes. Osmotic pumps, implanted subcutaneously in adult female rats, delivered ...

journal_title：Neuroreport

authors： Grunfeld JA,Tiedemann GJ,Westerman RA

更新日期：1993-06-01 00:00:00

abstract：:Extracellular recordings from neurosecretory cells in the hypothalamic paraventricular nucleus (PVN) displayed either an excitation or no response following electrical stimulation (5 Hz) of the A1 noradrenergic region of the ventrolateral medulla, and exhibited either an increase or no effect in neuronal activity in r...

journal_title：Neuroreport

authors： Tanaka J,Nomura M,Saito H

更新日期：1992-03-01 00:00:00

abstract：:Genetic factors are involved in variation in fetal alcohol spectrum disorders (FASD), which is also observed among various inbred mouse strains. The CD1 mouse strain is often used in toxicological and genetic experiments. However, there is little literature using this strain to study long-term neurologic abnormalities...

journal_title：Neuroreport

authors： Wei S,Xu Z,Gao J,Ding J,Xiao M

更新日期：2013-03-06 00:00:00

abstract：:AMPA (EC50 = 1.0 x 10(-6) M) and NMDA (EC50 = 1.3 x 10(-4) M) trigger 45Ca2+ influx in 13-day chick embryonic retinal explants. This agonist-driven cationic flux is specifically inhibited by typical competitive antagonists, such as 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 2-amino-7-phosphonoheptanoate (AP7), respec...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramírez G

更新日期：2000-07-14 00:00:00

abstract：:Abnormal sleep architecture and white matter hyperintensities (WMHs) may be involved in cognitive impairment. There is little evidence on the connections between WMHs and chronic insomnia disorder (CID). Therefore, we evaluated the severity of WMHs and polysomnography parameters as well as cognitive tests to explore t...

journal_title：Neuroreport

authors： Lu S,Song L,Wang D,Zhang X,Lv X,Yin H,Gao Y,Liu X,Tang J

更新日期：2019-06-12 00:00:00

abstract：:There is disagreement in the literature as to whether smooth pursuit latency is reduced when a temporal gap is introduced between the extinction of a central fixation target and the illumination of an eccentric moving target. This study confirms that in human subjects smooth pursuit latency is reduced by gaps and that...

journal_title：Neuroreport

authors： Knox PC

更新日期：1998-03-30 00:00:00