Acute marijuana effects on rCBF and cognition: a PET study.

abstract：:Using a guessing paradigm we measured visual sensitivity in the blind and normal half-fields of four cerebrally hemidecorticated patients. In the blind field, sensitivity was reduced by approximately 3 long units. Stimuli which produced significant detection also evoked conscious sensations of light and colour. Contro...

journal_title：Neuroreport

authors： Stoerig P,Faubert J,Ptito M,Diaconu V,Ptito A

更新日期：1996-08-12 00:00:00

abstract：:In order to accomplish desired movements, the nervous system must specify the movement dynamics: it must provide a signal that compensates for the mechanical constraints encountered during movement. Here we tested whether the population activity of Purkinje cells in the cerebellum specifies the dynamics for pursuit ey...

journal_title：Neuroreport

authors： Krauzlis RJ

更新日期：2000-04-07 00:00:00

abstract：:Brain trauma induces a multitude of reactions at molecular, cellular, and tissue levels, some of which are beneficial to recovery, whereas others are detrimental. Osteopontin (OPN), a glycosylated phosphoprotein, can be found in both the soluble form and as an extracellular matrix constituent in several tissues in the...

journal_title：Neuroreport

authors： Plantman S

更新日期：2012-08-01 00:00:00

abstract：:To investigate the phonological influences on the lexicosemantic process with a strong orthographic constraint, we used kanji (morphogram) homophone words and measured, using magnetoencephalography, the neural activities during the silent reading of prime-target pairs. The primes were phonologically the same as or dif...

journal_title：Neuroreport

authors： Wei Q,Ihara A,Hayakawa T,Murata T,Matsumoto E,Fujimaki N

更新日期：2007-11-19 00:00:00

abstract：:We examined the positioning of human retinotopic areas, which were considered to be homologous with the macaque visual cortices, by applying computational geometry to MRI and fMRI data sets. We found a similarity between the positional relationship of the retinotopic areas in the human and macaque visual cortex, despi...

journal_title：Neuroreport

authors： Ejima Y,Takahashi S

更新日期：2005-01-19 00:00:00

abstract：:We have previously reported that antidepressants such as desipramine (DMI) induce axonal regeneration of brain noradrenergic neurons. In the present experiments, the role of phospholipase A2 (PLA2) in the regeneration of brain noradrenergic axons was studied. Symmetrical sites of the rat frontal cortex were pretreated...

journal_title：Neuroreport

authors： Nakamura S

更新日期：1993-04-01 00:00:00

abstract：:We have evaluated the G1H line of transgenic mice overexpressing a familial ALS mutation of SOD1 (Gly-93-->Ala) in tasks assessing different aspects of motor function to determine how early these deficits could be detected and their order of appearance. The earliest deficits were observed in tests of muscle strength a...

journal_title：Neuroreport

authors： Barnéoud P,Lolivier J,Sanger DJ,Scatton B,Moser P

更新日期：1997-09-08 00:00:00

abstract：:Regional brain activity associated with intentional and incidental memory retrieval was studied with PET. Previously studied and new words were presented in either an intentional or an incidental memory task. Type of task was crossed with an encoding manipulation ('deep' vs 'shallow') which varied the probability that...

journal_title：Neuroreport

authors： Rugg MD,Fletcher PC,Frith CD,Frackowiak RS,Dolan RJ

更新日期：1997-03-24 00:00:00

abstract：:Previously we found that musicians have significantly larger anterior corpus callosum (CC). In the current study, we intended to replicate and extend our previous results using a new and larger sample of gender-matched subjects (56 right-handed professional musicians and 56 age- and handedness-matched controls). We fo...

journal_title：Neuroreport

authors： Lee DJ,Chen Y,Schlaug G

更新日期：2003-02-10 00:00:00

abstract：:The seven-transmembrane receptor Smoothened is essential for hedgehog signal transduction. In adulthood, the highest density of Smoothened mRNA is found in the granule cell layer of the dentate gyrus. There, Smoothened expression is regulated by the synaptic activity involving the glutamatergic transmission. The preci...

journal_title：Neuroreport

authors： Masdeu C,Bernard V,Faure H,Traiffort E,Ruat M

更新日期：2007-03-05 00:00:00

abstract：:The aim of the present study was to investigate the effect of intravenous or intrathecal (i.t.) administration of R-phenylisopropyladenosine (R-PIA), a selective A1 adenosine receptor agonist, on spontaneous scratching behaviour, a phenomenon presumably related to pain in a mononeuropathy model (sciatic nerve ligation...

journal_title：Neuroreport

authors： Sjölund KF,Sollevi A,Segerdahl M,Hansson P,Lundeberg T

更新日期：1996-07-29 00:00:00

abstract：:In order to ascertain whether disturbances of neurogenesis occur in chronic neurodegenerative disorders, we assessed hippocampal cell proliferation in the R6/1 transgenic mouse model of Huntington's disease (HD). Using BrdU labelling for dividing cells at two different time points (5 and 20 weeks) in transgenic and wi...

journal_title：Neuroreport

authors： Lazic SE,Grote H,Armstrong RJ,Blakemore C,Hannan AJ,van Dellen A,Barker RA

更新日期：2004-04-09 00:00:00

abstract：:Anti-leucine-rich glioma inactivated 1 (anti-LGI1) encephalitis is one of the most frequently encountered forms of autoimmune encephalitis. Many patients with anti-LGI1 encephalitis develop permanent hippocampal neuron loss and chronic neuropsychiatric symptoms, suggesting that LGI antibodies (Ab) might have a neuroto...

journal_title：Neuroreport

authors： Ayşit-Altuncu N,Ulusoy C,Öztürk G,Tüzün E

更新日期：2018-08-01 00:00:00

abstract：:Neural salient serine/arginine-rich protein 1 (NSSR1) expression has been found in mouse cerebral neurons, cerebellar Purkinje cells, pyramidal neurons and granule cells of dentate gyrus and regulates the pre-mRNA splicing of genes important for neural functions. In this study, we demonstrated that NSSR1 is expressed ...

journal_title：Neuroreport

authors： Peng ZY,Lee SC,Chen XH

更新日期：2007-10-29 00:00:00

abstract：:Spinal cord injury (SCI) causes motor dysfunction and depression, which hinders the recovery of motor function. Body weight-supported treadmill training (BWSTT) should be considered an effective method for functional rehabilitation after SCI, as it is an efficacious intervention in healthcare with no side effects. Bec...

journal_title：Neuroreport

authors： Liu CH,Zhao BL,Li WT,Zhou XH,Jin Z,An LB

更新日期：2020-12-16 00:00:00

abstract：:We previously reported that withdrawal from chronic cocaine produces supersensitivity of serotonin 2A receptors. We report here the minimum cocaine exposure necessary to produce withdrawal-associated increases in serotonin 2A receptor signaling in the frontal cortex. Rats withdrawn from cocaine treatments of 1, 3 or 7...

journal_title：Neuroreport

authors： Carrasco GA,Battaglia G

更新日期：2007-01-08 00:00:00

abstract：:Since the characterization of orphanin FQ (OFQ), the endogenous ligand of ORL1 receptor, much work has focused on its physiological functions. OFQ was reported to antagonize the effect of opioid-induced antinociception, although its mechanism remains obscure. In the present study, whole-cell patch clamp recording tech...

journal_title：Neuroreport

authors： Zhang M,Sun QL,Wan Y,Yao L,Yu YX,Han JS

更新日期：1998-06-22 00:00:00

abstract：:We inserted microelectrodes in eye movement-evoking cortices (EMECs) of cats and examined whether neurones in the EMECs received sensory input from guide signals and fired prior to saccades. The five EMECs were the medial wall of the hemisphere under the cruciate sulcus, the medical and lateral bank of the presylvian ...

journal_title：Neuroreport

authors： Tamai Y,Kimura A

更新日期：1996-10-02 00:00:00

abstract：:We have used double quantum filtered (DQF) 23Na+ nuclear magnetic resonance (NMR) spectroscopy without shift reagents in order to monitor intracellular Na+ (Na+i) in a cortical brain slice preparation. The external Na+ (Na+o) signal was reduced by 95% by the DQF sequence compared with the directly observed 23Na+. The ...

journal_title：Neuroreport

authors： Brooks KJ,Pirttilä TR,Kauppinen RA

更新日期：1993-02-01 00:00:00

abstract：:To confirm neural plasticity of the mouse hippocampo-prefrontal cortex (PFC) pathway, paired-pulse facilitation (PPF) and long-term potentiation (LTP) induction were determined in the pathway. In addition, we tested whether the plasticity differs in projections of the pathway from the dorsal (upper) and ventral (lower...

journal_title：Neuroreport

authors： Izaki Y,Takita M,Nomura M

更新日期：2001-05-08 00:00:00

abstract：:To test the hypothesis that correlated neuronal activity serves as the neuronal code for visual feature binding, we applied information theory techniques to multiunit activity recorded from pairs of V1 recording sites in anaesthetised cats while presenting either single or separate bar stimuli. We quantified the roles...

journal_title：Neuroreport

authors： Golledge HD,Panzeri S,Zheng F,Pola G,Scannell JW,Giannikopoulos DV,Mason RJ,Tovée MJ,Young MP

更新日期：2003-05-23 00:00:00

abstract：:We used an electrophysiological marker of linguistic discordance, the N400 wave, to investigate how linguistic and pseudo-linguistic stimuli are categorised during sleep as compared to waking. During wakefulness, signs of discordance detection were, as expected, greater for pseudo-words than for real but semantically ...

journal_title：Neuroreport

authors： Perrin F,Bastuji H,Garcia-Larrea L

更新日期：2002-07-19 00:00:00

abstract：:The changes of nitric oxide synthase (NOS) activity and nitrite level in rat brain regions after spatial learning were investigated. NOS activity was assayed by conversion of [3H]L-arginine to [3H]L-citrulline, and a sensitive fluorometric assay for quantification of nitrite was used. Compared with sham-trained rats, ...

journal_title：Neuroreport

authors： Chen J,Zhang S,Zuo P,Tang L

更新日期：1997-05-06 00:00:00

abstract：:BC200 is a long noncoding RNA expressed at high levels in the Alzheimer's disease (AD), and blocking of BC200 by siRNA is assumed to be an effective method for various disease therapy. We have established an AD cell model overexpressing amyloid β-peptide (Aβ)1-42 to observe the effects of BC200 on the cell viability a...

journal_title：Neuroreport

authors： Li H,Zheng L,Jiang A,Mo Y,Gong Q

更新日期：2018-09-05 00:00:00

abstract：:The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...

journal_title：Neuroreport

authors： Lovestone S,Anderton BH,Hartley C,Jensen TG,Jorgensen AL

更新日期：1996-04-10 00:00:00

abstract：:Retinal ganglion cells of the fish have the spontaneous capacity to regenerate after nerve crush, a phenomenon known to be facilitated by nerve growth factor (NGF). We have studied the high-affinity NGF receptor TrkA, during the regeneration of the tench (Tinca tinca L.) optic nerve, using immunocytochemical technique...

journal_title：Neuroreport

authors： Vecino E,Caminos E,Becker E,Rudkin BB,Evan GI,Martín-Zanca D

更新日期：1998-10-26 00:00:00

abstract：:The effects of huperzine A on memory impairments induced by scopolamine were evaluated using a radial maze task and inhibition of cholinesterase in vitro compared with the effects of E2020 and tacrine. Scopolamine (0.2 mg kg-1) significantly impaired spatial memory in rats. Huperzine A (0.1-0.4 mg kg-1, p.o.), E2020 (...

journal_title：Neuroreport

authors： Cheng DH,Ren H,Tang XC

更新日期：1996-12-20 00:00:00

abstract：:Recent study has demonstrated that high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) have the same effect to alleviate β-amyloid pathology in the hippocampus of APPswe/PS1dE9 (APP/PS1) mice. Activation of nucleotide binding and oligomerization domain-like receptor family pyrin d...

journal_title：Neuroreport

authors： Liang F,Huang T,Li B,Zhao Y,Zhang X,Xu B

更新日期：2020-03-25 00:00:00

abstract：:ErbBs are a family of receptors involved in the trophic maintenance of Schwann cells. Little is known about their expression changes during peripheral nerve regeneration. The aim of this study was thus to investigate variations in ErbBs after end-to-end and end-to-side nerve regeneration in the rat median nerve model....

journal_title：Neuroreport

authors： Audisio C,Nicolino S,Scevola A,Tos P,Geuna S,Battiston B,Perroteau I

更新日期：2008-10-29 00:00:00

abstract：:Immunohistochemistry for calcitonin gene-related peptide (CGRP) was performed on the dorsal root ganglion (DRG) and spinal cord in wildtype and knockout mice for Brn-3a. CGRP-immunoreactive (-IR) neurons were abundant in the DRG of wildtype, heterozygous and knockout mice. Cell size analysis revealed that CGRP-IR neur...

journal_title：Neuroreport

authors： Ichikawa H,Yamaai T,Mo Z,Xiang M,Sugimoto T

更新日期：2002-03-25 00:00:00