Acute marijuana effects on rCBF and cognition: a PET study.

abstract：:The present study examined the neuroprotective effects of choroid plexus isolated from adult rats and encapsulated within alginate microcapsules. In vitro, conditioned media from cultured choroid plexus produced a marked, dose-dependent protection of embryonic cortical neurons against serum deprivation-induced cell de...

journal_title：Neuroreport

authors： Borlongan CV,Skinner SJ,Geaney M,Vasconcellos AV,Elliott RB,Emerich DF

更新日期：2004-07-19 00:00:00

abstract：:Episodic memory for simple commands is better following enacted than verbal encoding. This has been proposed to be due to the possibility to base retrieval on motor information. Here we used PET to test the hypothesis that motor brain areas show increased retrieval-related activity following enacted compared to verbal...

journal_title：Neuroreport

authors： Nilsson LG,Nyberg L,Klingberg T,Aberg C,Persson J,Roland PE

更新日期：2000-07-14 00:00:00

abstract：:Motor fluctuations that ultimately complicate the response of most parkinsonian patients to levodopa therapy might represent a form of behavioral or neuronal plasticity. Since various forms of neuronal plasticity appear to be mediated by glutamate transmission through the N-methyl-D-aspartate (NMDA) receptor, the effe...

journal_title：Neuroreport

authors： Engber TM,Papa SM,Boldry RC,Chase TN

更新日期：1994-12-20 00:00:00

abstract：:The effects of a pharmacological blockade of the periaqueductal grey of the midbrain (PAG) on the elicitability of vocal fold movements from the facial motor cortex on the one hand and the anterior cingulate cortex and dorsomedial hypothalamus on the other were studied in the squirrel monkey. PAG blockade abolished vo...

journal_title：Neuroreport

authors： Jürgens U,Zwirner P

更新日期：1996-11-25 00:00:00

abstract：:High-resolution (< 50 microm) magnetic resonance imaging microscopy (MRM) has been used to identify brain regions and localization of excitotoxin-induced lesions in fixed rat brains, subsequently confirmed using standard histology. The anatomical extent of lesions identified by MRM was identical to that seen in histol...

journal_title：Neuroreport

authors： Lester DS,Lyon RC,McGregor GN,Engelhardt RT,Schmued LC,Johnson GA,Johannessen JN

更新日期：1999-03-17 00:00:00

abstract：:NONINVASIVE photolytic injury to targeted neuronal subpopulations in vivo causes unique, slowly progressive neuronal degeneration. To examine the mechanisms of degeneration toward development and transplantation studies, cytosolic calcium levels were measured in vitro from neocortical neurons after incorporation of ph...

journal_title：Neuroreport

authors： Sheen VL,Dreyer EB,Macklis JD

更新日期：1992-08-01 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity reproduces many of the features of Parkinson's disease (PD). alpha-Synuclein has been identified as a prominent component of the Lewy body (LB), the pathological hallmark of PD. MPTP-treated primates have been reported to develop intraneuronal inclusion...

journal_title：Neuroreport

authors： Kowall NW,Hantraye P,Brouillet E,Beal MF,McKee AC,Ferrante RJ

更新日期：2000-01-17 00:00:00

abstract：:Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson' disease motor imagery is impaired and that execution of overt movements is...

journal_title：Neuroreport

authors： Frak V,Cohen H,Pourcher E

更新日期：2004-06-28 00:00:00

abstract：:The reduced steroids 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and 3 alpha,21-di-hydroxy-5 alpha-pregnan-20-one (allotetrahydroDOC) are potent ligands of GABAA receptors. This study examined the possible modulatory effect of these metabolites on GABA inhibition of somatostatin release in cultured hypot...

journal_title：Neuroreport

authors： Tapia-Arancibia L,André M,Belmar J,Arancibia S

更新日期：1995-10-02 00:00:00

abstract：:The mechanism by which IL-1 beta exerts its actions in the brain during systemic inflammation is not fully understood, as neither IL-1 receptor gene expression nor IL-1 binding have been identified in significant levels in key areas that respond to IL-1 beta. Having hypothesized that perivascular nitric oxide (NO) mig...

journal_title：Neuroreport

authors： Wong ML,Bongiorno PB,al-Shekhlee A,Esposito A,Khatri P,Licinio J

更新日期：1996-11-04 00:00:00

abstract：:In the retina, the activation of metabotropic glutamate receptors (mGluRs) reduces the toxic effect of N-methyl-D-aspartate (NMDA). We have induced NMDA-mediated excitotoxicity in the adult rat retina by a single intraocular injection of NMDA. The damage that resulted was estimated by assessing the NMDA-induced loss o...

journal_title：Neuroreport

authors： Siliprandi R,Lipartiti M,Fadda E,Arban R,Kozikowski AP,Manev H

更新日期：1994-06-02 00:00:00

abstract：:We have previously reported that the developmental exposure of rats to altered gravity (1.65 g) from gestational day 8 to postnatal day 21 impacts motor functions and cerebellar structure. The present study examined whether the decrease in cerebellar mass accompanied by impaired performance on a rotorod in hypergravit...

journal_title：Neuroreport

authors： Sajdel-Sulkowska EM,Nguon K,Sulkowski ZL,Rosen GD,Baxter MG

更新日期：2005-12-19 00:00:00

abstract：:We previously reported that the methanol extract of Ashwagandha (roots of Dunal) induced dendrite extension in a human neuroblastoma cell line. In this study, we found that six of the 18 compounds isolated from the methanol extract enhanced neurite outgrowth in human neuroblastoma SH-SY5Y cells. Double immunostaining ...

journal_title：Neuroreport

authors： Kuboyama T,Tohda C,Zhao J,Nakamura N,Hattori M,Komatsu K

更新日期：2002-10-07 00:00:00

abstract：:The present study was based on earlier findings that the observation of a coherently moving long bar induced gamma-band activity in humans. The power in the EEG-gamma-band was reduced during the presentation of two incoherently moving short bars. The present study demonstrates the replicability of this cortical activi...

journal_title：Neuroreport

authors： Müller MM,Junghöfer M,Elbert T,Rochstroh B

更新日期：1997-07-28 00:00:00

abstract：:High concentrations of local anesthetics are neurotoxic, but the mechanism for this neurotoxicity is obscure. Here, we report increased concentrations of glutamate in the cerebrospinal fluid after intrathecal injections of high concentrations of tetracaine (a local anesthetic). The peak concentrations of glutamate aft...

journal_title：Neuroreport

authors： Ohtake K,Matsumoto M,Wakamatsu H,Kawai K,Nakakimura K,Sakabe T

更新日期：2000-04-07 00:00:00

abstract：:A number of epidemiological studies suggest that estrogen therapy is linked to a reduced risk of developing Alzheimer's disease (AD). The present study was conducted to evaluate the effect of 17beta-estradiol on beta-amyloid (Abeta)-induced toxicity and was performed in rat pheochromocytoma PC 12 cells by measuring th...

journal_title：Neuroreport

authors： Svensson AL,Nordberg A

更新日期：1999-11-26 00:00:00

abstract：:The distribution of activated NF-kappaB (p65) was studied in granule cells of the rat fascia dentata using confocal laser scanning microscopy and preembedding immunogold electron microscopy. Activated NF-kappaB, detected with a monoclonal antibody specific for the nuclear localization signal-epitope, was found in prox...

journal_title：Neuroreport

authors： Kaltschmidt B,Deller T,Frotscher M,Kaltschmidt C

更新日期：2000-03-20 00:00:00

abstract：:Neural salient serine/arginine-rich protein 1 (NSSR1) expression has been found in mouse cerebral neurons, cerebellar Purkinje cells, pyramidal neurons and granule cells of dentate gyrus and regulates the pre-mRNA splicing of genes important for neural functions. In this study, we demonstrated that NSSR1 is expressed ...

journal_title：Neuroreport

authors： Peng ZY,Lee SC,Chen XH

更新日期：2007-10-29 00:00:00

abstract：:Low doses of estrogen (E) were given to ovariectomized (OVX) rats and the ventromedial hypothalamic nucleus (VMN) was examined at the ultrastructural level. Administration of 10 micrograms of E for two consecutive days resulted in an increase in the number of axodendritic synapses in the VMN in comparison to OVX rats ...

journal_title：Neuroreport

authors： Frankfurt M,McEwen BS

更新日期：1991-07-01 00:00:00

abstract：:GPR39, an orphan G protein-coupled receptor, has been recently identified as the receptor for the bioactive peptide obestatin. Obestatin is secreted from the stomach and acts as an anti-appetite hormone. This activity is induced whether obestatin is administered intraperitoneally or intracerebroventricularly. GPR39 is...

journal_title：Neuroreport

authors： Jackson VR,Nothacker HP,Civelli O

更新日期：2006-05-29 00:00:00

abstract：:Other-race faces are less accurately recognized than same race faces but classified faster by race. Using event-related potentials (ERPs), we captured the brain temporal dynamics of face classification by race processing performed by 12 Caucasian participants. As expected, participants were faster to classify by race ...

journal_title：Neuroreport

authors： Caldara R,Rossion B,Bovet P,Hauert CA

更新日期：2004-04-09 00:00:00

abstract：:Regulation of CNS distribution of the human immunodeficiency virus (HIV) protease inhibitor saquinavir may involve ATP-dependent membrane-bound efflux transport proteins that are expressed in several brain cellular compartments. We recently characterized molecular and functional expression of one such transporter, mul...

journal_title：Neuroreport

authors： Dallas S,Ronaldson PT,Bendayan M,Bendayan R

更新日期：2004-05-19 00:00:00

abstract：:Experimental animals and patients are immobilized to allow continuous monitoring of physiological parameters. Restraint stress affects brain neurotransmitter levels and induces expression of immediate early genes. Whether immobilization stress affects outcomes in newborn animals which have suffered a hypoxic-ischaemic...

journal_title：Neuroreport

authors： Thoresen M,Bågenholm R,Løberg EM,Apriccna F

更新日期：1996-01-31 00:00:00

abstract：:Human scalp EEG has demonstrated that global coherence among distant areas increases during cognitive tasks, suggesting that oscillating neural activities work to generate global neuronal assemblies for cognitive functions. The theta oscillation in a frequency range of 4-8 Hz with large amplitudes which emerges during...

journal_title：Neuroreport

authors： Mizuhara H,Wang LQ,Kobayashi K,Yamaguchi Y

更新日期：2004-06-07 00:00:00

abstract：:Mental rotation performance has been found to produce one of the largest sex differences in cognition. Many theories suggest that this effect should be accompanied by a sex difference in functional cerebral asymmetry, but empirical data are more than equivocal probably because of (a) the use of inappropriate stimuli a...

journal_title：Neuroreport

authors： Pellkofer J,Jansen P,Heil M

更新日期：2014-08-06 00:00:00

abstract：:For the majority of neurones in cat striate cortex, the response to an optimal stimulus presented to one eye is suppressed when a stimulus of substantially different orientation is presented to the other eye. In order to determine the true orientational tuning of the underlying inhibitory interactions in the absence o...

journal_title：Neuroreport

authors： Sengpiel F,Freeman TC,Blakemore C

更新日期：1995-11-13 00:00:00

abstract：:The present study used the N400, an electrophysiological correlate of semantic processing, to investigate 19- and 24-month-old children's ability to integrate the meaning of words in a sentential context. Children listened passively to semantically appropriate sentences and to sentences in which the object noun violat...

journal_title：Neuroreport

authors： Friedrich M,Friederici AD

更新日期：2005-11-07 00:00:00

abstract：:Using structural MRI and whole-head EEG recordings, we analyzed the correlations between the anatomical parameters of the corpus callosum and the hemispheric distribution of the cortical movement-related potentials during right finger and shoulder movements in nine right-handed men. Statistically significant correlati...

journal_title：Neuroreport

authors： Stancák A Jr,Lücking CH,Kristeva-Feige R

更新日期：2000-02-07 00:00:00

abstract：:Consumers often rely on observable cues that hint at the hidden quality of a product. The aim of this study was to investigate brain activities associated with the country-of-origin (COO) effect and consumer evaluation of a product design. Electroencephalogram recordings were used to observe event-related brain potent...

journal_title：Neuroreport

authors： Min BK,Cho K,Sung J,Cho E

更新日期：2014-03-05 00:00:00

abstract：:Neuronal interferon-gamma (N-IFN-gamma), recently isolated from the nervous system, has a molecular weight distinct from that of lymphocyte-derived IFN-gamma, but crossreacts immunologically and shares certain bioactivities with this cytokine. In the rat brain N-IFN-gamma-immunoreactive perikarya were concentrated in ...

journal_title：Neuroreport

authors： Bentivoglio M,Florenzano F,Peng ZC,Kristensson K

更新日期：1994-12-20 00:00:00