Abstract:
:To test the hypothesis that correlated neuronal activity serves as the neuronal code for visual feature binding, we applied information theory techniques to multiunit activity recorded from pairs of V1 recording sites in anaesthetised cats while presenting either single or separate bar stimuli. We quantified the roles of firing rates of individual channels and of cross-correlations between recording sites in encoding of visual information. Between 89 and 96% of the information was carried by firing rates; correlations contributed 4-11% extra information. The distribution across the population of either correlation strength or correlation information did not co-vary systematically with changes in perception predicted by Gestalt psychology. These results suggest that firing rates, rather than correlations, are the main element of the population code for feature binding in primary visual cortex.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Golledge HD,Panzeri S,Zheng F,Pola G,Scannell JW,Giannikopoulos DV,Mason RJ,Tovée MJ,Young MPdoi
10.1097/01.wnr.0000073681.00308.9csubject
Has Abstractpub_date
2003-05-23 00:00:00pages
1045-50issue
7eissn
0959-4965issn
1473-558Xjournal_volume
14pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Glial cell line-derived neurotrophic factor (GDNF) exhibits neurotrophic properties on different types of neurones, including fetal motoneurones and embryonic neurones of sensory ganglia. We demonstrate that chronic injury to the adult rat sciatic nerve induces a rapid up-regulation of GDNF mRNA expression in Schwann ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199603220-00004
更新日期:1996-03-22 00:00:00
abstract::Decisions made on the basis of risk often require rapid evaluation of feedback before follow-up actions and feedback-related negativity in brain potential is sensitive to the poor outcome. The current study investigated the effects of feedback from one's own decision (Experiment 1) and feedback from observing others' ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000452
更新日期:2015-11-11 00:00:00
abstract::We studied the neural substrate of anticipation and learning of smooth pursuit eye movements in humans using fMRI. Both predictable and non-predictable eye movements, compared to baseline, activated a common network previously associated with oculomotor function. The temporal dynamics of activity in a subset of these ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200105250-00023
更新日期:2001-05-25 00:00:00
abstract::We have found that regeneration of the rat sciatic nerve is stimulated if the rats are exposed to a 50 Hz sinusoidal magnetic field. In this study we investigated the effect of a Ca2+ antagonist, methoxyverapamil (D600) on this response. D600 was administered to the regenerating segment of the nerve via implanted osmo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199209000-00023
更新日期:1992-09-01 00:00:00
abstract::In Purkinje cells from cerebellar slice cultures, low-threshold Ca spike (LTS) gives rise to complex bursts in the soma that resemble the complex spike induced by climbing fibers stimulation. We show that LTS is reduced by T-type and R-type Ca channel blockers (SNX-482, nickel, or mibefradil). We propose that LTS is g...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f4cb96
更新日期:2008-02-12 00:00:00
abstract::This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283455c23
更新日期:2011-06-22 00:00:00
abstract::Recent studies on cerebrospinal fluid (CSF) homeostasis emphasize the importance of water flux through the pericapillary (Virchow-Robin) space for both CSF production and reabsorption (Oreskovic and Klarica hypothesis), and challenge the classic CSF circulation theory, which proposes that CSF is primarily produced by ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000042
更新日期:2014-01-08 00:00:00
abstract::Sensory information from the genitourinary tract is transmitted to perineal muscle reflex circuits in the spinal cord and to the medullary reticular formation (MRF). This is the first report of a functional descending connection between neurons in the MRF and sensory inputs of the pudendal motoneuron reflex circuitry....
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199801260-00030
更新日期:1998-01-26 00:00:00
abstract::AMPA (EC50 = 1.0 x 10(-6) M) and NMDA (EC50 = 1.3 x 10(-4) M) trigger 45Ca2+ influx in 13-day chick embryonic retinal explants. This agonist-driven cationic flux is specifically inhibited by typical competitive antagonists, such as 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 2-amino-7-phosphonoheptanoate (AP7), respec...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200007140-00047
更新日期:2000-07-14 00:00:00
abstract::Nogo-A, a member of the reticulon family, is one of the most important myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the central nervous system. RhoA has been targeted pharmacologically to promote neurite outgrowth and functional recovery in the brain and spinal cord. However, the und...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32834a58e8
更新日期:2011-10-26 00:00:00
abstract::Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199710200-00011
更新日期:1997-10-20 00:00:00
abstract::We examined the neural correlates associated with a short gap between two identical pure tones (within-channel) and between two different tones (between-channel) in an odd-ball paradigm. Gap durations were selected such that a gap between identical tones was as discriminable as a gap between two different tones. Spati...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200409150-00011
更新日期:2004-09-15 00:00:00
abstract::The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-200011270-00047
更新日期:2000-11-27 00:00:00
abstract::Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200402090-00001
更新日期:2004-02-09 00:00:00
abstract::Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199901180-00018
更新日期:1999-01-18 00:00:00
abstract::Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000201503.15632.06
更新日期:2006-02-27 00:00:00
abstract::The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000644
更新日期:2016-09-28 00:00:00
abstract::Autophosphorylation of the alpha-isoform of Ca2+/calmodulin-dependent kinase II switches the kinase into an autonomous activity mode. This molecular switch is important for hippocampal long-term memory formation, which requires de novo gene transcription and protein synthesis. Here, we have studied whether auto-phosph...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175244.51084.bb
更新日期:2005-08-22 00:00:00
abstract::Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283646e65
更新日期:2013-10-02 00:00:00
abstract::Calpain activation has been implicated in the pathogenesis of Alzheimer's disease. Okadaic acid, a protein phosphatase-2A inhibitor, has been used in Alzheimer's disease research models to increase tau phosphorylation and induce neuronal death. We previously reported that okadaic acid induced predominant activation of...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000214398.04093.7f
更新日期:2006-05-15 00:00:00
abstract::Reading demands precise and efficient letter and word processing. This event-related potentials (ERP) study utilized massive repetition of visually presented single letters to trigger neuronal adaptation. Our aim was to explore whether the adaptation pattern of the N170 ERP component, serving as an indicator of neuron...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32835d20b1
更新日期:2013-01-23 00:00:00
abstract::The H-Tx rat is a polygenic inherited model of hydrocephalus. In order to identify disease-specific biomarkers associated with congenital hydrocephalus, comparative proteomic analysis was used to screen cerebellum proteins in H-Tx rats at 1 day after birth. Seven proteins showed significant changes in hydrocephalic H-...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200504250-00011
更新日期:2005-04-25 00:00:00
abstract::Electroconvulsive therapy (ECT) is an appropriate clinical model to investigate blood flow during seizures. In this study cerebral blood flow velocity (CBFV) was measured during 40 ECTs in 10 patients by means of transcranial Doppler sonography. EEG was recorded continuously. Under general anesthesia, the pre-convulsi...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199802160-00009
更新日期:1998-02-16 00:00:00
abstract::High concentrations of local anesthetics are neurotoxic, but the mechanism for this neurotoxicity is obscure. Here, we report increased concentrations of glutamate in the cerebrospinal fluid after intrathecal injections of high concentrations of tetracaine (a local anesthetic). The peak concentrations of glutamate aft...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200004070-00039
更新日期:2000-04-07 00:00:00
abstract::Secondary brain injury imposes great effects on the prognosis of patients following traumatic brain injury (TBI). Accumulating evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) could play a neuroprotective role in experimental TBI models by regulating the expression of numerous antioxidant, ant...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001205
更新日期:2019-03-20 00:00:00
abstract::Multiple signal classification is an alternative to the traditional dipole fitting source analysis methods. Our aim was to assess the clinical usefulness of this algorithm and to compare the localization of the epileptiform electroencephalography discharges with the regions of altered cerebral blood flow in 10 patient...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000230517.93714.f6
更新日期:2006-08-21 00:00:00
abstract::The phonemic structure of the maternal language determines the way of perceiving speech signals. A typical example is that native Japanese listeners map two English phonemes, /r/ and /l/, onto the same /R/. This perceptual assimilation of speech sounds has been associated with the left and/or right posterior perisylvi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f03f39
更新日期:2007-10-08 00:00:00
abstract::The immediate-early genes, especially c-fos, have been suggested to have an important role in neuronal plasticity and memory. However, it has been difficult to determine if in fact c-fos can participate in control of behaviour. Here we can report that direct unilateral infusion into the rat neostriatum of an antisense...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199312000-00024
更新日期:1993-12-13 00:00:00
abstract::In this study we have used the transgenic mouse model Tg2576 to analyze the involvement of anomalous loss of regulation of cdk5 and the stress kinases JNK and p38 in brain neuronal death as related to neurodegenerative disorders such as Alzheimer's disease. Previous studies on hippocampal cells led us to the discovery...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200312190-00023
更新日期:2003-12-19 00:00:00
abstract::The present paper reports how aluminium [Al(III)] at a concentration of 3.7 microM can activate the bovine erythrocytic enzyme acetylcholinesterase (AChE) by about 38% in vitro. This same activating effect was observed on AChE form human as well as from rat erythrocyte ghosts and murine neuroblastoma cells. The intera...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199409080-00023
更新日期:1994-09-08 00:00:00