Correlations, feature-binding and population coding in primary visual cortex.

Abstract:

:To test the hypothesis that correlated neuronal activity serves as the neuronal code for visual feature binding, we applied information theory techniques to multiunit activity recorded from pairs of V1 recording sites in anaesthetised cats while presenting either single or separate bar stimuli. We quantified the roles of firing rates of individual channels and of cross-correlations between recording sites in encoding of visual information. Between 89 and 96% of the information was carried by firing rates; correlations contributed 4-11% extra information. The distribution across the population of either correlation strength or correlation information did not co-vary systematically with changes in perception predicted by Gestalt psychology. These results suggest that firing rates, rather than correlations, are the main element of the population code for feature binding in primary visual cortex.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Golledge HD,Panzeri S,Zheng F,Pola G,Scannell JW,Giannikopoulos DV,Mason RJ,Tovée MJ,Young MP

doi

10.1097/01.wnr.0000073681.00308.9c

subject

Has Abstract

pub_date

2003-05-23 00:00:00

pages

1045-50

issue

7

eissn

0959-4965

issn

1473-558X

journal_volume

14

pub_type

杂志文章
  • GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury.

    abstract::Glial cell line-derived neurotrophic factor (GDNF) exhibits neurotrophic properties on different types of neurones, including fetal motoneurones and embryonic neurones of sensory ganglia. We demonstrate that chronic injury to the adult rat sciatic nerve induces a rapid up-regulation of GDNF mRNA expression in Schwann ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199603220-00004

    authors: Hammarberg H,Piehl F,Cullheim S,Fjell J,Hökfelt T,Fried K

    更新日期:1996-03-22 00:00:00

  • To bet or not to bet? The coding of bets modulates brain potentials in outcome evaluations.

    abstract::Decisions made on the basis of risk often require rapid evaluation of feedback before follow-up actions and feedback-related negativity in brain potential is sensitive to the poor outcome. The current study investigated the effects of feedback from one's own decision (Experiment 1) and feedback from observing others' ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000452

    authors: Liu Y,Dou K,Wang Y,Li J

    更新日期:2015-11-11 00:00:00

  • An fMRI study of anticipation and learning of smooth pursuit eye movements in humans.

    abstract::We studied the neural substrate of anticipation and learning of smooth pursuit eye movements in humans using fMRI. Both predictable and non-predictable eye movements, compared to baseline, activated a common network previously associated with oculomotor function. The temporal dynamics of activity in a subset of these ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200105250-00023

    authors: Schmid A,Rees G,Frith C,Barnes G

    更新日期:2001-05-25 00:00:00

  • D600, a Ca2+ antagonist, prevents stimulation of nerve regeneration by magnetic fields.

    abstract::We have found that regeneration of the rat sciatic nerve is stimulated if the rats are exposed to a 50 Hz sinusoidal magnetic field. In this study we investigated the effect of a Ca2+ antagonist, methoxyverapamil (D600) on this response. D600 was administered to the regenerating segment of the nerve via implanted osmo...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199209000-00023

    authors: Rusovan A,Kanje M

    更新日期:1992-09-01 00:00:00

  • Participation of low-threshold Ca2+ spike in the Purkinje cells complex spike.

    abstract::In Purkinje cells from cerebellar slice cultures, low-threshold Ca spike (LTS) gives rise to complex bursts in the soma that resemble the complex spike induced by climbing fibers stimulation. We show that LTS is reduced by T-type and R-type Ca channel blockers (SNX-482, nickel, or mibefradil). We propose that LTS is g...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3282f4cb96

    authors: Cavelier P,Lohof AM,Lonchamp E,Beekenkamp H,Mariani J,Bossu JL

    更新日期:2008-02-12 00:00:00

  • Hemodynamic signals of mixed messages during a social exchange.

    abstract::This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283455c23

    authors: Zucker NL,Green S,Morris JP,Kragel P,Pelphrey KA,Bulik CM,LaBar KS

    更新日期:2011-06-22 00:00:00

  • Water influx into cerebrospinal fluid is primarily controlled by aquaporin-4, not by aquaporin-1: 17O JJVCPE MRI study in knockout mice.

    abstract::Recent studies on cerebrospinal fluid (CSF) homeostasis emphasize the importance of water flux through the pericapillary (Virchow-Robin) space for both CSF production and reabsorption (Oreskovic and Klarica hypothesis), and challenge the classic CSF circulation theory, which proposes that CSF is primarily produced by ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000042

    authors: Igarashi H,Tsujita M,Kwee IL,Nakada T

    更新日期:2014-01-08 00:00:00

  • Brainstem microstimulation differentially inhibits pudendal motoneuron reflex inputs.

    abstract::Sensory information from the genitourinary tract is transmitted to perineal muscle reflex circuits in the spinal cord and to the medullary reticular formation (MRF). This is the first report of a functional descending connection between neurons in the MRF and sensory inputs of the pudendal motoneuron reflex circuitry....

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199801260-00030

    authors: Johnson RD,Hubscher CH

    更新日期:1998-01-26 00:00:00

  • Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants.

    abstract::AMPA (EC50 = 1.0 x 10(-6) M) and NMDA (EC50 = 1.3 x 10(-4) M) trigger 45Ca2+ influx in 13-day chick embryonic retinal explants. This agonist-driven cationic flux is specifically inhibited by typical competitive antagonists, such as 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 2-amino-7-phosphonoheptanoate (AP7), respec...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200007140-00047

    authors: Burgos JS,Barat A,Ramírez G

    更新日期:2000-07-14 00:00:00

  • Protein kinase B is involved in Nogo-66 inhibiting neurite outgrowth in PC12 cells.

    abstract::Nogo-A, a member of the reticulon family, is one of the most important myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the central nervous system. RhoA has been targeted pharmacologically to promote neurite outgrowth and functional recovery in the brain and spinal cord. However, the und...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32834a58e8

    authors: Wang H,Shen J,Xiong N,Zhao H,Chen Y

    更新日期:2011-10-26 00:00:00

  • Human short latency cortical responses to somatosensory stimulation. A high resolution EEG study.

    abstract::Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-199710200-00011

    authors: Urbano A,Babiloni F,Babiloni C,Ambrosini A,Onorati P,Rossini PM

    更新日期:1997-10-20 00:00:00

  • Within- and between-channel gap detection in the human auditory cortex.

    abstract::We examined the neural correlates associated with a short gap between two identical pure tones (within-channel) and between two different tones (between-channel) in an odd-ball paradigm. Gap durations were selected such that a gap between identical tones was as discriminable as a gap between two different tones. Spati...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200409150-00011

    authors: Heinrich A,Alain C,Schneider BA

    更新日期:2004-09-15 00:00:00

  • Acute marijuana effects on rCBF and cognition: a PET study.

    abstract::The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-200011270-00047

    authors: O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

    更新日期:2000-11-27 00:00:00

  • Sex differences in functional activation patterns revealed by increased emotion processing demands.

    abstract::Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200402090-00001

    authors: Hall GB,Witelson SF,Szechtman H,Nahmias C

    更新日期:2004-02-09 00:00:00

  • Grape polyphenols protect neurodegenerative changes induced by chronic ethanol administration.

    abstract::Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199901180-00018

    authors: Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

    更新日期:1999-01-18 00:00:00

  • Expression of chaperonin 60 in the hippocampus of the streptozotocin diabetic rat.

    abstract::Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000201503.15632.06

    authors: Yuan J,Young BJ,Martinus RD

    更新日期:2006-02-27 00:00:00

  • Effects of aging on P300 between late young-age and early middle-age adulthood: an electroencephalogram event-related potential study.

    abstract::The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000644

    authors: Bourisly AK

    更新日期:2016-09-28 00:00:00

  • Alpha-isoform of Ca2+/calmodulin-dependent kinase II autophosphorylation is required for memory consolidation-specific transcription.

    abstract::Autophosphorylation of the alpha-isoform of Ca2+/calmodulin-dependent kinase II switches the kinase into an autonomous activity mode. This molecular switch is important for hippocampal long-term memory formation, which requires de novo gene transcription and protein synthesis. Here, we have studied whether auto-phosph...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000175244.51084.bb

    authors: von Hertzen LS,Giese KP

    更新日期:2005-08-22 00:00:00

  • Effect of transcranial direct current stimulation on vestibular-ocular and vestibulo-perceptual thresholds.

    abstract::Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283646e65

    authors: Kyriakareli A,Cousins S,Pettorossi VE,Bronstein AM

    更新日期:2013-10-02 00:00:00

  • Calpain activation in okadaic-acid-induced neurodegeneration.

    abstract::Calpain activation has been implicated in the pathogenesis of Alzheimer's disease. Okadaic acid, a protein phosphatase-2A inhibitor, has been used in Alzheimer's disease research models to increase tau phosphorylation and induce neuronal death. We previously reported that okadaic acid induced predominant activation of...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000214398.04093.7f

    authors: Yoon S,Choi J,Huh JW,Hwang O,Kim D

    更新日期:2006-05-15 00:00:00

  • Neuronal response specificity as a marker of reading proficiency: two-fold nature of the N170 revealed after massive repetition.

    abstract::Reading demands precise and efficient letter and word processing. This event-related potentials (ERP) study utilized massive repetition of visually presented single letters to trigger neuronal adaptation. Our aim was to explore whether the adaptation pattern of the N170 ERP component, serving as an indicator of neuron...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32835d20b1

    authors: Korinth SP,Sommer W,Breznitz Z

    更新日期:2013-01-23 00:00:00

  • Analysis of cerebellum proteomics in the hydrocephalic H-Tx rat.

    abstract::The H-Tx rat is a polygenic inherited model of hydrocephalus. In order to identify disease-specific biomarkers associated with congenital hydrocephalus, comparative proteomic analysis was used to screen cerebellum proteins in H-Tx rats at 1 day after birth. Seven proteins showed significant changes in hydrocephalic H-...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200504250-00011

    authors: Li X,Miyajima M,Mineki R,Taka H,Murayama K,Arai H

    更新日期:2005-04-25 00:00:00

  • Cerebral hemodynamics during electrically induced seizures.

    abstract::Electroconvulsive therapy (ECT) is an appropriate clinical model to investigate blood flow during seizures. In this study cerebral blood flow velocity (CBFV) was measured during 40 ECTs in 10 patients by means of transcranial Doppler sonography. EEG was recorded continuously. Under general anesthesia, the pre-convulsi...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-199802160-00009

    authors: Vollmer-Haase J,Folkerts HW,Haase CG,Deppe M,Ringelstein EB

    更新日期:1998-02-16 00:00:00

  • Glutamate release and neuronal injury after intrathecal injection of local anesthetics.

    abstract::High concentrations of local anesthetics are neurotoxic, but the mechanism for this neurotoxicity is obscure. Here, we report increased concentrations of glutamate in the cerebrospinal fluid after intrathecal injections of high concentrations of tetracaine (a local anesthetic). The peak concentrations of glutamate aft...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200004070-00039

    authors: Ohtake K,Matsumoto M,Wakamatsu H,Kawai K,Nakakimura K,Sakabe T

    更新日期:2000-04-07 00:00:00

  • Expression of nuclear factor erythroid 2-related factor 2 following traumatic brain injury in the human brain.

    abstract::Secondary brain injury imposes great effects on the prognosis of patients following traumatic brain injury (TBI). Accumulating evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) could play a neuroprotective role in experimental TBI models by regulating the expression of numerous antioxidant, ant...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001205

    authors: He Y,Yan H,Ni H,Liang W,Jin W

    更新日期:2019-03-20 00:00:00

  • Source analysis of epileptic discharges using multiple signal classification analysis.

    abstract::Multiple signal classification is an alternative to the traditional dipole fitting source analysis methods. Our aim was to assess the clinical usefulness of this algorithm and to compare the localization of the epileptiform electroencephalography discharges with the regions of altered cerebral blood flow in 10 patient...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000230517.93714.f6

    authors: Beniczky S,Oturai PS,Alving J,Sabers A,Herning M,Fabricius M

    更新日期:2006-08-21 00:00:00

  • Functional neuroanatomy of speech processing within the temporal cortex.

    abstract::The phonemic structure of the maternal language determines the way of perceiving speech signals. A typical example is that native Japanese listeners map two English phonemes, /r/ and /l/, onto the same /R/. This perceptual assimilation of speech sounds has been associated with the left and/or right posterior perisylvi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3282f03f39

    authors: Hara NF,Nakamura K,Kuroki C,Takayama Y,Ogawa S

    更新日期:2007-10-08 00:00:00

  • Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine.

    abstract::The immediate-early genes, especially c-fos, have been suggested to have an important role in neuronal plasticity and memory. However, it has been difficult to determine if in fact c-fos can participate in control of behaviour. Here we can report that direct unilateral infusion into the rat neostriatum of an antisense...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199312000-00024

    authors: Sommer W,Bjelke B,Ganten D,Fuxe K

    更新日期:1993-12-13 00:00:00

  • Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease.

    abstract::In this study we have used the transgenic mouse model Tg2576 to analyze the involvement of anomalous loss of regulation of cdk5 and the stress kinases JNK and p38 in brain neuronal death as related to neurodegenerative disorders such as Alzheimer's disease. Previous studies on hippocampal cells led us to the discovery...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200312190-00023

    authors: Otth C,Mendoza-Naranjo A,Mujica L,Zambrano A,Concha II,Maccioni RB

    更新日期:2003-12-19 00:00:00

  • Activation of acetylcholinesterase by aluminium(III): the relevance of the metal species.

    abstract::The present paper reports how aluminium [Al(III)] at a concentration of 3.7 microM can activate the bovine erythrocytic enzyme acetylcholinesterase (AChE) by about 38% in vitro. This same activating effect was observed on AChE form human as well as from rat erythrocyte ghosts and murine neuroblastoma cells. The intera...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199409080-00023

    authors: Zatta P,Zambenedetti P,Bruna V,Filippi B

    更新日期:1994-09-08 00:00:00