Expression of the kallikrein gene family in normal and Alzheimer's disease brain.

abstract：:It is a matter of dispute whether or not recurrent epileptic seizures cause neuronal damage in the human brain. We approached this question by measuring the volumes of the amygdala, hippocampus and parahippocampal gyrus with magnetic resonance imaging in 15 controls, 13 unmedicated patients with newly diagnosed epilep...

journal_title：Neuroreport

authors： Saukkonen A,Kälviäinen R,Partanen K,Vainio P,Riekkinen P,Pitkänen A

更新日期：1994-12-30 00:00:00

abstract：:Consumers often rely on observable cues that hint at the hidden quality of a product. The aim of this study was to investigate brain activities associated with the country-of-origin (COO) effect and consumer evaluation of a product design. Electroencephalogram recordings were used to observe event-related brain potent...

journal_title：Neuroreport

authors： Min BK,Cho K,Sung J,Cho E

更新日期：2014-03-05 00:00:00

abstract：:We examined the role of main and external cuneate nuclei neurons in processing sensory information during forelimb passive movement. We recorded activity of neurons using circular and figure-eight trajectories, at different speeds, in anaesthetized rats. A multivariate regression analysis was performed to correlate ne...

journal_title：Neuroreport

authors： Garifoli A,Caserta C,Bosco G,Lombardo SA,Casabona A,Perciavalle V

更新日期：2002-03-04 00:00:00

abstract：:Inflammatory and immune responses are known to be involved in the pathogenesis of Alzheimer's disease (AD). NF-kappaB is a major transcription factor that plays a central role in the inflammatory and immune responses and is regulated by I-kappaB through an autoregulatory feedback system. Southwestern immunohistochemis...

journal_title：Neuroreport

authors： Yoshiyama Y,Arai K,Hattori T

更新日期：2001-08-28 00:00:00

abstract：:Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...

journal_title：Neuroreport

authors： Hall GB,Witelson SF,Szechtman H,Nahmias C

更新日期：2004-02-09 00:00:00

abstract：:We investigated the brain mechanisms enabling one automatically discriminate phoneme category irrespective of the large inter-speaker variability in the acoustic features of the voices. For this purpose, subjects were presented with 450 different speech stimuli, each uttered by a different speaker, belonging to three ...

journal_title：Neuroreport

authors： Shestakova A,Brattico E,Huotilainen M,Galunov V,Soloviev A,Sams M,Ilmoniemi RJ,Näätänen R

更新日期：2002-10-07 00:00:00

abstract：:TECTA and DFNA5 are the mouse orthologues of the human deafness-associated genes TECTA and DFNA5. To determine how expression of these genes is regulated during development, relative mRNA abundance was examined in mice by non-radioactive RT-PCR. TECTA mRNA was detected on embryonic day 15 (E15), increased to its highe...

journal_title：Neuroreport

authors： Maeda Y,Fukushima K,Kasai N,Maeta M,Nishizaki K

更新日期：2001-10-29 00:00:00

abstract：:Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

journal_title：Neuroreport

authors： Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

更新日期：1999-01-18 00:00:00

abstract：:Psychotic-like episodes in divers exposed to high pressure have been attributed to either the high-pressure neurological syndrome, confinement in pressure chamber, the subject's personality, or the addition of nitrogen or hydrogen to the basic helium-oxygen breathing mixture used for deep diving. Alternatively, it is ...

journal_title：Neuroreport

authors： Abraini JH

更新日期：1995-03-07 00:00:00

abstract：:The time course of responses to repeated presentations of affective stimuli is well characterized in healthy individuals but remains to be characterized in patients with bipolar disorder. Using functional magnetic resonance imaging, we compared early-stage and late-stage brain activation during a two-block fearful fac...

journal_title：Neuroreport

authors： Killgore WD,Gruber SA,Yurgelun-Todd DA

更新日期：2008-10-08 00:00:00

abstract：:It is well known that dendritic cells play a key role in producing antigen-specific responses. Inversely, tolerogenic dendritic cells (TolDCs), a specialized subset, induce immune tolerance and negatively regulate autoimmune responses. Statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the m...

journal_title：Neuroreport

authors： Chen Z,Yang D,Peng X,Lin J,Su Z,Li J,Zhang X,Weng Y

更新日期：2018-03-07 00:00:00

abstract：:Birds are capable of dexterous sensory-motor activities such as tool use. Reaching is a crucial component of tool use and is a vision-guided behavior in primates, in which arm movement is monitored online in a stable visual frame. However, vision-guided reaching in primates is enabled by anatomical separation of the h...

journal_title：Neuroreport

authors： Kanai M,Matsui H,Watanabe S,Izawa E

更新日期：2014-09-10 00:00:00

abstract：:Absence seizures are known to originate from disruptions within the corticothalamocortical network; however, the precise underlying cellular and molecular mechanisms that induce hypersynchronicity and hyperexcitability are debated and likely to be complex and multifactorial. Recent studies implicate impaired thalamic ...

journal_title：Neuroreport

authors： Seo S,Leitch B

更新日期：2017-12-13 00:00:00

abstract：:Amyloid plaques and neurofibrillary tangles are the major pathological hallmarks of Alzheimer's disease. Neurofibrillary tangles are composed of filaments and paired helical filaments containing polymerized hyperphosphorylated tau protein. Derlin proteins are a family of proteins that are conserved in all eukaryotes, ...

journal_title：Neuroreport

authors： Honjo Y,Ito H,Horibe T,Shimada H,Nakanishi A,Mori H,Takahashi R,Kawakami K

更新日期：2012-07-11 00:00:00

abstract：:Expression of monocarboxylate transporter MCT1 was studied in archival tissues from human CNS using antibodies to the carboxyl-terminal end of MCT1. Sections of neocortex, hippocampus and cerebellum of brains from 10 adult autopsy patients who died from other than CNS disease, and from archival surgical biopsy specime...

journal_title：Neuroreport

authors： Froberg MK,Gerhart DZ,Enerson BE,Manivel C,Guzman-Paz M,Seacotte N,Drewes LR

更新日期：2001-03-26 00:00:00

abstract：:NMR signal intensities in five regions of the midsagittal corpus callosum were measured in autism patients and normal controls. An age-related increase in signal was observed in the anterior regions in both groups. No significant differences in intensity were detected between the groups. The finding of normal myelinat...

journal_title：Neuroreport

authors： Belmonte M,Egaas B,Townsend J,Courchesne E

更新日期：1995-06-19 00:00:00

abstract：:Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...

journal_title：Neuroreport

authors： Tani M,Onimaru H,Ikeda K,Kawakami K,Homma I

更新日期：2010-12-08 00:00:00

abstract：:Since the characterization of orphanin FQ (OFQ), the endogenous ligand of ORL1 receptor, much work has focused on its physiological functions. OFQ was reported to antagonize the effect of opioid-induced antinociception, although its mechanism remains obscure. In the present study, whole-cell patch clamp recording tech...

journal_title：Neuroreport

authors： Zhang M,Sun QL,Wan Y,Yao L,Yu YX,Han JS

更新日期：1998-06-22 00:00:00

abstract：:Newly hatched domestic chicks serve as an important model for experimental studies of neural and behavioral plasticity. Brain-derived neurotrophic factor (BDNF) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. Here we show ...

journal_title：Neuroreport

authors： Yamaguchi S,Aoki N,Kobayashi D,Kitajima T,Iikubo E,Katagiri S,Matsushima T,Homma KJ

更新日期：2011-12-07 00:00:00

abstract：:In addition to the study of pathological conditions, magnetic resonance spectroscopy can provide useful information about brain-behavior relationships in normal subjects. Recently, there have been reports of correlations between N-acetylaspartate (NAA) values and cognitive functions in normal adults. We tested the pos...

journal_title：Neuroreport

authors： Giménez M,Junqué C,Narberhaus A,Caldú X,Segarra D,Vendrell P,Bargalló N,Mercader JM

更新日期：2004-03-22 00:00:00

abstract：:Two well-known appetite-regulatory peptides, leptin and cocaine- and amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet known how they interact in the nucleus accumbens, an important region mediating the rewarding effects of drugs of abuse. Using th...

journal_title：Neuroreport

authors： Cho BR,Yoon HS,Kim WY,Vezina P,Kim JH

更新日期：2017-08-02 00:00:00

abstract：:Plasminogen activator inhibitor-1 is a serpin that regulates the activities of plasminogen activators. However, its physiological roles in the CNS are incompletely understood. We have found that plasminogen activator inhibitor-1 has a novel biological function in the CNS: the contribution to survival of neurites on ne...

journal_title：Neuroreport

authors： Soeda S,Imatoh T,Ochiai T,Koyanagi S,Shimeno H

更新日期：2004-04-09 00:00:00

abstract：:Paraoxonase polymorphisms have been associated with amyotrophic lateral sclerosis (ALS). Paraoxonases are detoxifying enzymes involved in the metabolism of organophosphates. We tested the hypothesis that genetic variation within paraoxonase genes would interact with the environmental exposure to paraoxonase substrates...

journal_title：Neuroreport

authors： Diekstra FP,Beleza-Meireles A,Leigh NP,Shaw CE,Al-Chalabi A

更新日期：2009-01-28 00:00:00

abstract：:Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...

journal_title：Neuroreport

authors： Kempster S,Collins ME,Edington N

更新日期：2004-10-05 00:00:00

abstract：:It is unclear whether the neural algorithm that underlies stereoscopic vision in birds incorporates both low level (camouflage breaking) and high level (depth ordering) comparisons of information available to each of the eyes. Both visual functions were successfully tested by examining transitive inference performance...

journal_title：Neuroreport

authors： van der Willigen RF,Frost BJ,Wagner H

更新日期：1998-04-20 00:00:00

abstract：:The aim of this study was to define the effects of a potent inhibitor of tyrosine phosphatases, sodium orthovanadate (0.1-100 microM for up to 48 h), on dentate gyrus cells (DGC) in culture. Treatment with 100 microM orthovanadate evoked a delayed form of cell death. To examine the possible involvement of apoptosis in...

journal_title：Neuroreport

authors： Figiel I,Kaczmarek L

更新日期：1997-07-28 00:00:00

abstract：:The octave illusion is experienced when two simultaneous tones, separated by one octave and presented to the opposite ears, are continuously reversed between the two ears. Subjects consistently report a sequence of alternating single tones: the high tone in the right ear and the low in the left. We wished to determine...

journal_title：Neuroreport

authors： Ross J,Tervaniemi M,Näätänen R

更新日期：1996-12-20 00:00:00

abstract：:The aim was to study whether there is indication of a dissociation in processing of visuospatial and colour information in working memory in humans. Experimental subjects performed visuospatial and colour n-back tasks with and without visuospatial and colour distractive stimuli presented in the middle of the delay per...

journal_title：Neuroreport

authors： Vuontela V,Rämä P,Raninen A,Aronen HJ,Carlson S

更新日期：1999-08-02 00:00:00

abstract：:We constructed two replication-deficient recombinant adenovirus vectors coding human basic fibroblast growth factor (bFGF), one with and one without the interleukin-2 (IL-2) secretory signal sequence and examined their neurotrophic effects on primary neuronal cells in vitro. The primary neuronal cells were successfull...

journal_title：Neuroreport

authors： Matsuoka N,Miyatake S,Yukawa H,Takahashi JC,Saiki M,Mori H,Ishii K,Akimoto M,Hamada H,Hashimoto N

更新日期：2000-06-26 00:00:00

abstract：:Orienting attention to a spatial location facilitates responding to a subsequent target at that location, but inhibits the response if attention is oriented away from that location before the target appears there. This inhibitory effect of attention re-orienting, called inhibition of return (IOR), occurs in vision, he...

journal_title：Neuroreport

authors： Prime DJ,Tata MS,Ward LM

更新日期：2003-03-03 00:00:00