Medial temporal MR spectroscopy is related to memory performance in normal adolescent subjects.

Abstract:

:In addition to the study of pathological conditions, magnetic resonance spectroscopy can provide useful information about brain-behavior relationships in normal subjects. Recently, there have been reports of correlations between N-acetylaspartate (NAA) values and cognitive functions in normal adults. We tested the possible specific relationship between the NAA/choline (Cho) ratio in the medial temporal lobe and memory performance in normal adolescents. The medial temporal NAA/Cho ratio was unrelated to age, gender and general intelligence but presented a clear correlation with several memory measures. In the regression analysis two memory variables (RAVLT learning and a face-name recognition task) explained 55.6% of NAA/Cho variance. We conclude that NAA values in the medial temporal lobe are related to memory abilities but not to global intelligence in normal adolescent subjects.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Giménez M,Junqué C,Narberhaus A,Caldú X,Segarra D,Vendrell P,Bargalló N,Mercader JM

doi

10.1097/00001756-200403220-00026

subject

Has Abstract

pub_date

2004-03-22 00:00:00

pages

703-7

issue

4

eissn

0959-4965

issn

1473-558X

pii

00001756-200403220-00026

journal_volume

15

pub_type

杂志文章
  • The effect of electromagnetic fields emitted by mobile phones on human sleep.

    abstract::Previous research has suggested that exposure to radiofrequency electromagnetic fields increases electroencephalogram spectral power in non-rapid eye movement sleep. Other sleep parameters have also been affected following exposure. We examined whether aspects of sleep architecture show sensitivity to electromagnetic ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000186593.79705.3c

    authors: Loughran SP,Wood AW,Barton JM,Croft RJ,Thompson B,Stough C

    更新日期:2005-11-28 00:00:00

  • The responses of visual cortical neurons encode differences across saccades.

    abstract::Primate vision consists mostly of periods of stable fixation separated by rapid saccadic eye movements. Each saccade brings a new scene onto the retina, and each new scene results in a burst of activity in the neurons of visual cortex. It might be expected that the activity of these neurons should only represent what ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200301200-00020

    authors: Gawne TJ,Woods JM

    更新日期:2003-01-20 00:00:00

  • Chronic alcohol exposure decreases brain intracellular free magnesium concentration in rats.

    abstract::Phosphorus magnetic resonance spectroscopy was used to determine effects of acute and chronic alcohol exposure on brain intracellular free magnesium concentration (Mgf) and bioenergetic state in rats. Acute alcohol (3 mg kg-1, i.p.) resulted in a transient ( < 2h) decline in brain Mgf and cytosolic phosphorylation rat...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199508000-00011

    authors: Mullins PG,Vink R

    更新日期:1995-08-21 00:00:00

  • Plasma homocysteine and the methylenetetrahydrofolate reductase C677T gene variant: lack of association with schizophrenia.

    abstract::Disturbances in methyl-carbon metabolism, which result in hyperhomocysteinemia, have been associated with schizophrenia. Homozygosity for the T677 allele of the methylenetetrahydrofolate reductase (MTHFR) gene, which encodes for a thermolabile enzyme associated with hyperhomocysteinemia, has been found to be increased...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199907130-00008

    authors: Virgos C,Martorell L,Simó JM,Valero J,Figuera L,Joven J,Labad A,Vilella E

    更新日期:1999-07-13 00:00:00

  • A PET study of axis orientation discrimination.

    abstract::We examined the cortical areas showing increased activation related to axis orientation discrimination in hand movement and perception by positron emission tomography (PET) in right-handed normal human subjects while they performed a hand orientation (HO) task and an orientation discrimination (OD) task. In the OD tas...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-199801260-00020

    authors: Taira M,Kawashima R,Inoue K,Fukuda H

    更新日期:1998-01-26 00:00:00

  • Numerical distance effect in the N240 component in a number-matching task.

    abstract::The event-related potential technique was used to investigate the time course and scalp-potential topography for the numerical distance effect in a number-matching task. Twenty undergraduates judged whether a number matched or did not match another number presented 1.5 s earlier. Compared with number pairs with a 'sma...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000221840.12632.9f

    authors: Zhou X,Chen C,Dong Q,Zhang H,Chen C,Qiao S,Zhao H,Jiang T,Guo Y

    更新日期:2006-07-17 00:00:00

  • Intestinal STC-1 cells respond to five basic taste stimuli.

    abstract::STC-1 cells have been established as an enteroendocrine cell line from the small intestine. By monitoring the level of intracellular Ca using a calcium-imaging technique, cellular responses of intestinal STC-1 cells to compounds of five basic tastants were investigated. Although this cell line was known to respond to ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3282f242d3

    authors: Saitoh O,Hirano A,Nishimura Y

    更新日期:2007-12-03 00:00:00

  • Temporal attention is involved in the enhancement of attentional capture with task difficulty: an event-related brain potential study.

    abstract::In a three-stimulus oddball task, the amplitude of P3a elicited by deviant stimuli increases with an increase in the difficulty of discriminating between standard and target stimuli (i.e. task-difficulty effect on P3a), indicating that attentional capture by deviant stimuli is enhanced with an increase in task difficu...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000837

    authors: Sugimoto F,Kimura M,Takeda Y,Katayama J

    更新日期:2017-08-16 00:00:00

  • Secondary inhibition of 2-ketoglutarate dehydrogenase complex by MPTP.

    abstract::The parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridine (MPP+) acts through inhibition of complex I of the electron transport chain. Recent evidence suggests that it may also act through inhibition of 2-ketoglutarate dehydrogenase complex (KDHC). We confirmed this observation in isolated rat liver mitochondria ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199808240-00018

    authors: Joffe GT,Parks JK,Parker WD Jr

    更新日期:1998-08-24 00:00:00

  • Physiology of morphologically identified cells of the bullfrog fungiform papilla.

    abstract::Voltage-gated ionic current and the response to quinine were studied on the four types of morphologically identified taste cells of the bullfrog fungiform papilla by whole-cell patch clamp recording with a Lucifer yellow-filled pipette. Dye-coupled type Ia cells (mucous cells) did not show voltage-activated currents. ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200109170-00040

    authors: Takeuchi H,Tsunenari T,Kurahashi T,Kaneko A

    更新日期:2001-09-17 00:00:00

  • Decreased white matter integrity in mesial temporal lobe epilepsy: a machine learning approach.

    abstract::Statistical analysis on diffusion tensor imaging has been used extensively in mesial temporal lobe epilepsy (mTLE) and most studies report decrease in fractional anisotropy (FA) in multiple white matter regions. However, these findings vary across studies and between regions. Therefore, in this study, we used tract-ba...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000178

    authors: An J,Fang P,Wang W,Liu Z,Hu D,Qiu S

    更新日期:2014-07-09 00:00:00

  • Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons.

    abstract::DNA methylation is important for controlling gene expression and is catalyzed by DNA methyltransferase (Dnmt1) an enzyme abundant in brain. We recently demonstrated that mice expressing reduced levels of Dnmt1 are protected from cerebral ischemia. Here, we used the cre/loxP system to produce conditional mutants that l...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200112040-00032

    authors: Endres M,Fan G,Meisel A,Dirnagl U,Jaenisch R

    更新日期:2001-12-04 00:00:00

  • Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease.

    abstract::In this study we have used the transgenic mouse model Tg2576 to analyze the involvement of anomalous loss of regulation of cdk5 and the stress kinases JNK and p38 in brain neuronal death as related to neurodegenerative disorders such as Alzheimer's disease. Previous studies on hippocampal cells led us to the discovery...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200312190-00023

    authors: Otth C,Mendoza-Naranjo A,Mujica L,Zambrano A,Concha II,Maccioni RB

    更新日期:2003-12-19 00:00:00

  • Leptin in the nucleus accumbens blocks the increase of GluA1 phosphorylation induced by acute cocaine administration.

    abstract::Leptin in the rat's nucleus accumbens (NAcc) core has previously shown to disrupt the effects of acute administration of cocaine on both locomotor activity and the phosphorylation levels of glycogen synthase kinase 3β. In the present study, we further measured the phosphorylation levels of GluA1 after bilateral microi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001001

    authors: Lee JW,Kim WY,Kim JH

    更新日期:2018-04-11 00:00:00

  • Phospholipase A2-induced changes in AMPA receptor: an autoradiographic study.

    abstract::The expression of long-term potentiation and learning of a classical conditioning task increase [3H]-AMPA binding in hippocampus. Phospholipase A2 (PLA2) has been proposed to underly these changes, as PLA2 treatment of membrane preparations increases the affinity of AMPA receptors for agonists. We demonstrate here tha...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:

    authors: Tocco G,Massicotte G,Standley S,Thompson RF,Baudry M

    更新日期:1992-06-01 00:00:00

  • Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury.

    abstract::Activity of calpains and caspase-3 inferred from proteolysis of the cytoskeletal protein alpha-spectrin into signature spectrin breakdown products (SBDPs) was used to provide the first systematic and simultaneous comparison of changes in activity of these two families of cysteine proteases after traumatic brain injury...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199808030-00002

    authors: Pike BR,Zhao X,Newcomb JK,Posmantur RM,Wang KK,Hayes RL

    更新日期:1998-08-03 00:00:00

  • Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers.

    abstract::Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) are assumed to provide trophic support via a target-derived, retrograde mechanism of action. However, recent studies suggest that neurotrophic factors can act in an autocrine fashion and perhaps even in an anterograde direction similar to neurotrans...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199705260-00008

    authors: Smith MA,Zhang LX,Lyons WE,Mamounas LA

    更新日期:1997-05-27 00:00:00

  • Extracellular guanosine increases astrocyte cAMP: inhibition by adenosine A2 antagonists.

    abstract::Both extracellular guanosine and adenosine stimulated astrocyte proliferation in vitro and increased intracellular cAMP 6-fold within 2 min. The effects of both guanosine and adenosine on proliferation and cAMP levels were inhibited by antagonists of adenosine A2 receptors but augmented by A1 receptor antagonists. The...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199111000-00007

    authors: Rathbone MP,Middlemiss PJ,DeLuca B,Jovetich M

    更新日期:1991-11-01 00:00:00

  • Stimulus novelty and emotion perception: the near absence of habituation in the visual cortex.

    abstract::In rapid serial visual presentation of pictures, an early event-related brain potential component shows enlarged negativity over occipital regions for emotional pictures compared with neutral pictures. The present study examined whether the processing of emotional target pictures varies as a function of stimulus repet...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000203355.88061.c6

    authors: Schupp HT,Stockburger J,Codispoti M,Junghöfer M,Weike AI,Hamm AO

    更新日期:2006-03-20 00:00:00

  • Differential expression of c-fos following administration of two tremorgenic agents: harmaline and oxotremorine.

    abstract::The regional distribution of c-Fos expression in the brain after the administration of two tremorgenic agents was studied. In both the harmaline- and oxotremorin-treated rats, c-Fos-positive neurons were extensively distributed in the basal ganglia nuclei and the cerebellum. Additionally, in the harmaline-treated rats...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200008030-00010

    authors: Miwa H,Nishi K,Fuwa T,Mizuno Y

    更新日期:2000-08-03 00:00:00

  • Hemodynamic signals of mixed messages during a social exchange.

    abstract::This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283455c23

    authors: Zucker NL,Green S,Morris JP,Kragel P,Pelphrey KA,Bulik CM,LaBar KS

    更新日期:2011-06-22 00:00:00

  • Monoamine neurons in the human brain stem: anatomy, magnetic resonance imaging findings, and clinical implications.

    abstract::By using high-resolution, conventional, and neuromelanin-sensitive magnetic resonance imaging techniques, we reviewed the normal anatomy of the nuclei consisting of monoamine neurons such as dopaminergic, noradrenergic, and serotoninergic neurons and noted the changes in these nuclei that occur in some degenerative an...

    journal_title:Neuroreport

    pub_type: 杂志文章,评审

    doi:10.1097/WNR.0b013e328315a637

    authors: Sasaki M,Shibata E,Tohyama K,Kudo K,Endoh J,Otsuka K,Sakai A

    更新日期:2008-11-19 00:00:00

  • Evidence that L-arginine possesses proconvulsant effects mediated through nitric oxide.

    abstract::Increasing evidence suggests a neurotransmitter role for NO in the mammalian CNS. We have now studied the behavioural and electrocortical (ECoG) profile of rats injected into the lateral cerebral ventricle (ICV) with L-arginine (L-arg), the endogenous donor of the guanidino group from which NO physiologically originat...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199105000-00014

    authors: Mollace V,Bagetta G,Nisticò G

    更新日期:1991-05-01 00:00:00

  • Analysis of hippocampal atrophy in alcoholic patients by a Kohonen feature map.

    abstract::We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and B6 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200402090-00031

    authors: Kurth C,Wegerer V,Reulbach U,Lewczuk P,Kornhuber J,Steinhoff BJ,Bleich S

    更新日期:2004-02-09 00:00:00

  • Down-regulation of the rat serotonin transporter upon exposure to a selective serotonin reuptake inhibitor.

    abstract::The serotonin transporter (SERT) terminates serotonergic neurotransmission by rapid reuptake of 5-hydroxytryptamine (5-HT) into the nerve terminal or axonal varicosities. SERT represents the target of various antidepressants which inhibit 5-HT transport and are widely used for the pharmacotherapy of depression. Here, ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200107200-00027

    authors: Horschitz S,Hummerich R,Schloss P

    更新日期:2001-07-20 00:00:00

  • Absence of increased hypothalamic nitric oxide synthase gene expression during the preovulatory LH surge in middle-aged rats.

    abstract::This study was performed to test the hypothesis that diminution in the preovulatory luteinizing hormone (LH) surge in middle-aged (MA) rats may be related to altered activity in nitric oxide (NO)ergic neurons. To begin to test the hypothesis, gene expression of hypothalamic NO synthase (NOS), the enzyme that catalyzes...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199812210-00006

    authors: Sahu A

    更新日期:1998-12-21 00:00:00

  • Malonate-induced cortico-motoneuron death is attenuated by NT-4, but not by BDNF or NT-3.

    abstract::Neurotrophins are promising candidates to slow the progression of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease in which spinal and cortical motoneurons selectively degenerate. In a long-term in vitro model, malonate-induced toxicity and cell death of motoneurons have been demonstrated. Here we stud...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200105250-00013

    authors: Van Westerlaak MG,Bär PR,Cools AR,Joosten EA

    更新日期:2001-05-25 00:00:00

  • Positioning of retinotopic areas and patterning of cerebral cortex layout.

    abstract::We examined the positioning of human retinotopic areas, which were considered to be homologous with the macaque visual cortices, by applying computational geometry to MRI and fMRI data sets. We found a similarity between the positional relationship of the retinotopic areas in the human and macaque visual cortex, despi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200501190-00003

    authors: Ejima Y,Takahashi S

    更新日期:2005-01-19 00:00:00

  • Cortical thickness of supratemporal plane predicts auditory N1 amplitude.

    abstract::The auditory-evoked potential's N1 component of the scalp electroencephalogram is a well-established measure of electrical brain activity. The N1 reflects basic auditory processing and is modulated by auditory experience, for instance, by musical training. Here, we explore a possible correlation between the auditory N...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32835abc5c

    authors: Liem F,Zaehle T,Burkhard A,Jäncke L,Meyer M

    更新日期:2012-12-05 00:00:00

  • Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study.

    abstract::Anti-leucine-rich glioma inactivated 1 (anti-LGI1) encephalitis is one of the most frequently encountered forms of autoimmune encephalitis. Many patients with anti-LGI1 encephalitis develop permanent hippocampal neuron loss and chronic neuropsychiatric symptoms, suggesting that LGI antibodies (Ab) might have a neuroto...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001055

    authors: Ayşit-Altuncu N,Ulusoy C,Öztürk G,Tüzün E

    更新日期:2018-08-01 00:00:00