Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease.

abstract：:This study investigated whether neural mechanisms of self-face recognition are modulated by attention by recording event-related brain potentials associated with self-face recognition. Participants identified head orientations of self-faces and familiar or unfamiliar other faces presented briefly at the center of the ...

journal_title：Neuroreport

authors： Sui J,Zhu Y,Han S

更新日期：2006-03-20 00:00:00

abstract：:Somatostatin sst2(a) receptor was observed, by immunofluorescence, in ependymal cells and in tanycytes of the wall of the ventricle and the hypothalamic recess of the male rat median eminence. Strong immunoreactivity for the receptor protein was observed in lateral tanycytes (alpha-type) while a moderate signal was se...

journal_title：Neuroreport

authors： Hashemi SH,Li JY,Schindler M,Dahlström A

更新日期：2001-07-03 00:00:00

abstract：:Functional neuroimaging studies of handedness have traditionally focused on exploring regionally activated discrepancies, yet little is known regarding the effect of handedness on functional connections of brain regions. Here, we reported the relationship between cerebellar functional connectivity patterns and handedn...

journal_title：Neuroreport

authors： He Y,Zang Y,Jiang T,Gong G,Xie S,Xiao J

更新日期：2006-01-23 00:00:00

abstract：:Changes of serum immunoglobulin (Ig) concentrations may occur in both brain tumours and lumbar disc diseases (LDD). The purpose of this study was to investigate the changes of pre- and post-operative serum Ig levels in brain tumours and LDDs. Serum IgG, IgA and IgM levels were measured in 127 patients with brain tumou...

journal_title：Neuroreport

authors： Yüceer N,Arasil E,Temiz C

更新日期：2000-02-07 00:00:00

abstract：:Central sensitization is a fundamental mechanism contributing to acute and chronic pain conditions. Our previous studies have documented a glutamatergic, purinergic and glial-dependent central sensitization that can be induced in rat medullary dorsal horn nociceptive neurons by mustard oil application to the tooth pul...

journal_title：Neuroreport

authors： Chiang CY,Li Z,Dostrovsky JO,Sessle BJ

更新日期：2010-02-17 00:00:00

abstract：:The acute effects of ethanol and acetaldehyde on neuropeptide mRNA expression in the arcuate nucleus (ARC) was assessed. Acetaldehyde was increased in blood following ethanol with cyanamide (a potent inhibitor of aldehyde dehydrogenase) administration. Acetaldehyde is a toxin which can cause a variety of adverse effec...

journal_title：Neuroreport

authors： Kinoshita H,Jessop DS,Finn DP,Coventry TL,Roberts DJ,Ameno K,Ijiri I,Harbuz MS

更新日期：2000-11-09 00:00:00

abstract：:Neuronal activity may lead to long lasting changes in cell phenotype through induction of genes such as c-fos which encode transcriptional regulatory factors. Odor-activated olfactory bulb cells exhibit increases in c-fos mRNA expression. The present study examined whether odor stimulation of awake rats also leads to ...

journal_title：Neuroreport

authors： Guthrie KM,Gall CM

更新日期：1995-11-13 00:00:00

abstract：:We report two functional magnetic resonance imaging experiments which reveal similarities and differences between perceptual and imaginal networks within the single visual submodality of colour. The first experiment contrasted viewing of a coloured and grey-scale Mondrian display, while the second contrasted a relativ...

journal_title：Neuroreport

authors： Howard RJ,ffytche DH,Barnes J,McKeefry D,Ha Y,Woodruff PW,Bullmore ET,Simmons A,Williams SC,David AS,Brammer M

更新日期：1998-04-20 00:00:00

abstract：:Little is known regarding opioid receptors in the human cerebellum. The present [11C]diprenorphine PET study investigated opioid receptor binding in the human cerebellum in vivo, and showed a differential binding level in cerebellar cortex, vermis and dentate nuclei. The additional study in vitro of opioid receptors i...

journal_title：Neuroreport

authors： Schadrack J,Willoch F,Platzer S,Bartenstein P,Mahal B,Dworzak D,Wester HJ,Zieglgänsberger W,Tölle TR

更新日期：1999-02-25 00:00:00

abstract：:Diabetic peripheral neuropathy is the most common complication of diabetes mellitus and leads to sensory symptoms, including diabetic neuropathic pain (DNP). DNP is a major public health problem because it has a considerable impact on life quality of diabetes mellitus patients. Therefore, development of novel effectiv...

journal_title：Neuroreport

authors： Li P,Xiong DL,Sun WP,Xu SY

更新日期：2018-12-05 00:00:00

abstract：:We examined the induction of progesterone receptor-immunoreactive (PR-ir) cells by estrogen in the rat preoptic area and ventromedial hypothalamic nucleus. Ovariectomized young (3-month-old) and old (24-month-old) female rats were treated with estrogen or cholesterol for 4 days. Estrogen significantly increased PR-ir ...

journal_title：Neuroreport

authors： Furuta M,Fukushima A,Chiba S,Sano A,Akema T,Kimura F,Funabashi T

更新日期：2010-08-04 00:00:00

abstract：:Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg mo...

journal_title：Neuroreport

authors： Sharpe LG,Jaffe JH

更新日期：1990-09-01 00:00:00

abstract：:The majority of retinal ganglion cells innervating the suprachiasmatic nucleus are intrinsically light sensitive, while the rest are conventional ganglion cells that collect inputs through conventional photoreceptors. Here we report a rarely encountered ganglion cell that had a dendritic field covering approximately 1...

journal_title：Neuroreport

authors： Pu M,Chen B,Li RS,Tay D,So KF

更新日期：2006-10-02 00:00:00

abstract：:Thyroid hormone receptor beta2 (TRbeta2) controls the patterning of cone opsin photopigments that mediate colour vision. We raised an antiserum against TRbeta2 to study cone photoreceptor development by western blot and immunostaining analyses. TRbeta2-positive cells first appeared between embryonic day 10 (E10) and E...

journal_title：Neuroreport

authors： Ng L,Ma M,Curran T,Forrest D

更新日期：2009-04-22 00:00:00

abstract：:An exaggerated startle response caused by mutations of the alpha 1 subunit gene of the inhibitory glycine receptor (GLRA1) is the key symptom of human hyperekplexia or startle disease. The recessive mouse mutant spasmodic (spd) carries a missense mutation in the corresponding murine Glra1 gene which reduces the affini...

journal_title：Neuroreport

authors： Koch M,Kling C,Becker CM

更新日期：1996-02-29 00:00:00

abstract：:Melatonin, a hormone from the pineal gland, was tested for its anticonvulsant effects in male gerbils. Daily administration of melatonin (25 micrograms injection-1, s.c.) for ten weeks reduced the number and severity of seizures (total convulsion score: 7.67 +/- 1.83 in controls vs 2.47 +/- 0.90 in melatonin-injected ...

journal_title：Neuroreport

authors： Champney TH,Champney JA

更新日期：1992-12-01 00:00:00

abstract：:Neuronal interferon-gamma (N-IFN-gamma), recently isolated from the nervous system, has a molecular weight distinct from that of lymphocyte-derived IFN-gamma, but crossreacts immunologically and shares certain bioactivities with this cytokine. In the rat brain N-IFN-gamma-immunoreactive perikarya were concentrated in ...

journal_title：Neuroreport

authors： Bentivoglio M,Florenzano F,Peng ZC,Kristensson K

更新日期：1994-12-20 00:00:00

abstract：:We evaluated the effects of chemical lesions on hindpaw inflammation-induced Fos protein expression in spinoparabrachial neurons that were retrogradely labeled by Fluoro-Gold. The descending serotoninergic and noradrenergic pathways were destroyed by the selective neurotoxins, 5,7-DHT and DSP-4, respectively. After 5,...

journal_title：Neuroreport

authors： Wei F,Dubner R,Ren K

更新日期：1999-06-03 00:00:00

abstract：:Prior work has shown that kappa opioids may attenuate the effects of analgesic mu receptor agonists in some neural circuits related to pain modulation. This study examined whether hypoalgesia following exposure to a signal for shock is attenuated by infusions of the kappa agonist U69593 into the rostral ventromedial m...

journal_title：Neuroreport

authors： Foo H,Helmstetter FJ

更新日期：2000-10-20 00:00:00

abstract：:Prolonged activation of brain N-methyl-D-aspartic acid (NMDA) receptors increases intraneuronal (Ca2+) and nitric oxide (NO) synthesis, and may be responsible for neuronal death in acute brain insults and chronic neurodegenerative diseases. NO can be converted in vitro to toxic hydroxyl (OH) radical. Using microdialys...

journal_title：Neuroreport

authors： Hammer B,Parker WD Jr,Bennett JP Jr

更新日期：1993-10-25 00:00:00

abstract：:Deficiencies of Ca2+ homeostasis are proposed to play an important role in neuronal ageing and/or neurodegeneration. The aim of this study was to investigate, in a defined neuronal population, primary cerebellar granule neuron culture, the time-dependent changes in Ca2+ homeostasis and compare them with data obtained ...

journal_title：Neuroreport

authors： Toescu EC,Verkhratsky A

更新日期：2000-11-27 00:00:00

abstract：:Alopecia areata (AA) is a dermatosis involving the sudden occurrence of bald patches on the scalp. Although the aetiology is unknown, experimental data indicate that cutaneous microcirculation plays an important role. The skin is richly innervated by neuropeptidergic sensory nerves that help regulate microvascular cir...

journal_title：Neuroreport

authors： Rossi R,Del Bianco E,Isolani D,Baccari MC,Cappugi P

更新日期：1997-03-24 00:00:00

abstract：:Removal of the labyrinthine organs on one side results in static and dynamic disturbances. Some functional recovery occurs over time and is paralleled in frogs by an increase in the efficacy of central vestibular pathways. Here, we report concomitant increases in dorsal root evoked ventral root responses in the brachi...

journal_title：Neuroreport

authors： Straka H,Kunkel A,Dieringer N

更新日期：1993-09-01 00:00:00

abstract：:Anti-leucine-rich glioma inactivated 1 (anti-LGI1) encephalitis is one of the most frequently encountered forms of autoimmune encephalitis. Many patients with anti-LGI1 encephalitis develop permanent hippocampal neuron loss and chronic neuropsychiatric symptoms, suggesting that LGI antibodies (Ab) might have a neuroto...

journal_title：Neuroreport

authors： Ayşit-Altuncu N,Ulusoy C,Öztürk G,Tüzün E

更新日期：2018-08-01 00:00:00

abstract：:Microglia are the only immunocompetent cells resident in the central nervous system which are capable of protecting the brain from infection and tumors. These resident macrophages possess a vast array of mechanisms for the destruction of bacteria and tumor cells. One of these mechanisms involves the generation of nitr...

journal_title：Neuroreport

authors： Wood PL,Choksi S,Bocchini V

更新日期：1994-04-14 00:00:00

abstract：:The distribution of neurones expressing neuropeptide Y (NPY) mRNA in the brain of the goldfish was investigated using a non-radioactive in situ hybridization technique. Neurones expressing NPY mRNA were located in cell groups previously shown to exhibit NPY immunoreactivity in the ventral telencephalon, thalamus, opti...

journal_title：Neuroreport

authors： Vecino E,Perez MT,Ekström P

更新日期：1994-12-30 00:00:00

abstract：:The effects of huperzine A on memory impairments induced by scopolamine were evaluated using a radial maze task and inhibition of cholinesterase in vitro compared with the effects of E2020 and tacrine. Scopolamine (0.2 mg kg-1) significantly impaired spatial memory in rats. Huperzine A (0.1-0.4 mg kg-1, p.o.), E2020 (...

journal_title：Neuroreport

authors： Cheng DH,Ren H,Tang XC

更新日期：1996-12-20 00:00:00

abstract：:Neurone-specific enolase immunoreactivity (NSE-IR) was examined in the hippocampal dentate gyrus 5 h, 24 h and 6 days following local injection of N-methyl-D-aspartate (NMDA), and was compared with Nissl substance and acid fuchsin staining. Five and 24 hours post-injection extracellular NSE-IR was increased, and the n...

journal_title：Neuroreport

authors： Comer AM,Lees GJ,Lipski J

更新日期：1994-12-20 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy was used to determine effects of acute and chronic alcohol exposure on brain intracellular free magnesium concentration (Mgf) and bioenergetic state in rats. Acute alcohol (3 mg kg-1, i.p.) resulted in a transient ( < 2h) decline in brain Mgf and cytosolic phosphorylation rat...

journal_title：Neuroreport

authors： Mullins PG,Vink R

更新日期：1995-08-21 00:00:00

abstract：:During vertebrate neural development, inductive signals derived from the roof plate specify dorsal neural cell types of spinal cord as well as adjacent dermomytotome. Noggin has been demonstrated to play a pivotal role in this signaling network but how its expression is regulated remains unclear. To investigate this i...

journal_title：Neuroreport

authors： Geng X,Xiao L,Tao Q,Hu R,Rupp RA,Ding X

更新日期：2003-12-02 00:00:00