Opioid receptors in the human cerebellum: evidence from [11C]diprenorphine PET, mRNA expression and autoradiography.

abstract：:We investigated the age-related change in the distribution of a molecular marker for neural stem and precursor cells, Musashi-1, in the olfactory epithelium of mice from 1 day up to 16 months of age using immunohistochemistry. We also compared the distribution pattern of Musashi-1 with that of growth-associated protei...

journal_title：Neuroreport

authors： Watanabe K,Kondo K,Takeuchi N,Okano H,Yamasoba T

更新日期：2007-05-07 00:00:00

abstract：:We investigated the brain mechanisms enabling one automatically discriminate phoneme category irrespective of the large inter-speaker variability in the acoustic features of the voices. For this purpose, subjects were presented with 450 different speech stimuli, each uttered by a different speaker, belonging to three ...

journal_title：Neuroreport

authors： Shestakova A,Brattico E,Huotilainen M,Galunov V,Soloviev A,Sams M,Ilmoniemi RJ,Näätänen R

更新日期：2002-10-07 00:00:00

abstract：:beta-N-methylamino-L-alanine (L-BMAA) is an excitotoxin whose neurodegenerative effects are associated with its agonist properties at the N-methyl-D-aspartate (NMDA) receptor. We measured the effects of L-BMAA on inositol phosphate (InsP) formation in primary cultured striatal neurons. This culture is almost devoid of...

journal_title：Neuroreport

authors： Manzoni OJ,Prezeau L,Bockaert J

更新日期：1991-10-01 00:00:00

abstract：:The functional integrity of the 'on' and 'off' neurovisual pathways has been examined in the central visual fields of normal (n = 13), glaucomatous (n = 21) and ocular hypertensive (n = 21) individuals. The detection thresholds to light increments (onsets = bright spots) and light decrements (offsets = dark spots) on ...

journal_title：Neuroreport

authors： Mutlukan E

更新日期：1993-09-03 00:00:00

abstract：:Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) are assumed to provide trophic support via a target-derived, retrograde mechanism of action. However, recent studies suggest that neurotrophic factors can act in an autocrine fashion and perhaps even in an anterograde direction similar to neurotrans...

journal_title：Neuroreport

authors： Smith MA,Zhang LX,Lyons WE,Mamounas LA

更新日期：1997-05-27 00:00:00

abstract：:To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...

journal_title：Neuroreport

authors： Távora-Vieira D,Boisvert I,McMahon CM,Maric V,Rajan GP

更新日期：2013-09-11 00:00:00

abstract：:The aim of the present study was to determine if both inactivating and non-inactivating potassium currents occur in skeletal muscle cells at early times in culture. Whole cell current was recorded from embryonic muscle cells within 4-10 h of plating. We found that in the cells which had an outward current, half had a ...

journal_title：Neuroreport

authors： Moody-Corbett F,Gilbert R

更新日期：1992-04-01 00:00:00

abstract：:Histamine-related drugs are commonly used in the treatment of vertigo and related vestibular disorders. Their site and mechanism of action, however, are still poorly understood. To increase our knowledge of the histaminergic system in the vestibular organs, we have investigated the expression of H1 and H3 histamine re...

journal_title：Neuroreport

authors： Botta L,Tritto S,Perin P,Laforenza U,Gastaldi G,Zampini V,Zucca G,Valli S,Masetto S,Valli P

更新日期：2008-03-05 00:00:00

abstract：:The role of dopamine D1A receptors in mediating amphetamine-induced sensitization was investigated using the D1A-deficient mouse. During the drug pre-exposure phase, D1A-deficient and control mice were injected for five consecutive days with saline or amphetamine (2 mg/kg, i.p.). Locomotor activity was measured on the...

journal_title：Neuroreport

authors： Crawford CA,Drago J,Watson JB,Levine MS

更新日期：1997-07-28 00:00:00

abstract：:Reward-processing neurocircuitry has been delineated using verbal or visual processing and/or decision-making tasks. We examined more basic processes of listening to enjoyable music in healthy and depressed patients. The paradigm was passive, individualized, and brief. Sixteen depressed and 15 control individuals prov...

journal_title：Neuroreport

authors： Osuch EA,Bluhm RL,Williamson PC,Théberge J,Densmore M,Neufeld RW

更新日期：2009-08-26 00:00:00

abstract：:We investigated whether cerebellar transcranial magnetic stimulation (C-TMS) facilitates the excitability of the ipsilateral soleus motoneuron pool in resting humans, and whether the facilitation is modulated by a task that promotes cerebellar activity. A test tibial nerve stimulus evoking the H-reflex from the right ...

journal_title：Neuroreport

authors： Matsugi A,Mori N,Uehara S,Kamata N,Oku K,Mukai K,Nagano K

更新日期：2014-12-03 00:00:00

abstract：:Hypoxia or global ischemia causes rapid loss of consciousness and a sudden increase in spontaneous transmitter release suggesting that coordinated synaptic activity is impaired. Gamma oscillations (30-100 Hz) are thought to provide for binding of parallel processed information in the brain, contributing to cognition a...

journal_title：Neuroreport

authors： Fano S,Behrens CJ,Heinemann U

更新日期：2007-11-19 00:00:00

abstract：:Effects of adrenalectomy on the 5-HT1A receptor agonist 8-hydroxy-2-di-n-(propylamino)tetralin (8-OH-DPAT)- and 2-deoxy-D-glucose (2-DG)-induced hyperphagia were investigated in rats. Prior adrenalectomy completely inhibited 2-DG-induced hyperphagia, although it did not affect increases in food intake elicited by 8-OH...

journal_title：Neuroreport

authors： Yamada J,Sugimoto Y,Yoshikawa T

更新日期：1998-06-01 00:00:00

abstract：:Microglial activation is thought to contribute to the progression of selective motor neuron death during amyotrophic lateral sclerosis (ALS). As minocycline has been shown to inhibit microglial activation, the therapeutic efficacy of this tetracycline derivative in the G93A mice model for familial ALS was tested. This...

journal_title：Neuroreport

authors： Van Den Bosch L,Tilkin P,Lemmens G,Robberecht W

更新日期：2002-06-12 00:00:00

abstract：:Diabetes is often associated with impairments in brain functioning. However, the injury of specific functioning areas of the brain is not clear. To address this problem, the present study was designed to investigate possible brain functioning change in specific brain areas, particularly in areas associated with vision...

journal_title：Neuroreport

authors： Wang Z,Lu Z,Li J,Pan C,Jia Z,Chen H,Ge X

更新日期：2017-01-18 00:00:00

abstract：:Using a guessing paradigm we measured visual sensitivity in the blind and normal half-fields of four cerebrally hemidecorticated patients. In the blind field, sensitivity was reduced by approximately 3 long units. Stimuli which produced significant detection also evoked conscious sensations of light and colour. Contro...

journal_title：Neuroreport

authors： Stoerig P,Faubert J,Ptito M,Diaconu V,Ptito A

更新日期：1996-08-12 00:00:00

abstract：:In order to ascertain whether disturbances of neurogenesis occur in chronic neurodegenerative disorders, we assessed hippocampal cell proliferation in the R6/1 transgenic mouse model of Huntington's disease (HD). Using BrdU labelling for dividing cells at two different time points (5 and 20 weeks) in transgenic and wi...

journal_title：Neuroreport

authors： Lazic SE,Grote H,Armstrong RJ,Blakemore C,Hannan AJ,van Dellen A,Barker RA

更新日期：2004-04-09 00:00:00

abstract：:The existence of a CRF-dependent inhibition of GnRH transcription was investigated using a neuronal GnRH-expressing cell line (Gn11) stably transfected with mouse (-611 bp) or chicken (-3000 bp) GnRH promoter/luciferase reporter constructs. The presence of the CRF-R1 receptor was established using a specific CRF-R1 an...

journal_title：Neuroreport

authors： Tellam DJ,Perone MJ,Dunn IC,Radovick S,Brennand J,Rivier JE,Castro MG,Lovejoy DA

更新日期：1998-10-05 00:00:00

abstract：:This study demonstrates the neural system potentially involved in the representation of, and choice between, stimulus classifications in an ambiguous, novel, decision-making task. This difficult choice behaviour is taken as an example of a basic executive processing task. Subjects heard sounds that were consonant-vowe...

journal_title：Neuroreport

authors： Scott SK,Holmes A,Friston KJ,Wise RJ

更新日期：2000-05-15 00:00:00

abstract：:Recent studies have shown the nutrient-sensing systems transmitting nutritive information from the gut to the brain. However neural activity evoked by ingested dietary nutrients has not been investigated adequately. Using functional magnetic resonance imaging, we demonstrated that rat forebrain responded to intragastr...

journal_title：Neuroreport

authors： Tsurugizawa T,Kondoh T,Torii K

更新日期：2008-07-16 00:00:00

abstract：:To compare the maximum Hoffmann reflex (H-reflex) and the maximum M-wave (H : M) ratio of the H-reflex in men and women when all participants showed similar saliva levels of estradiol and progesterone. This is a cohort design study involving healthy men and women with a mean age of 22.4±3.4 years. The H : M ratio of t...

journal_title：Neuroreport

authors： Hoffman M,Norcross M,Johnson S

更新日期：2018-03-07 00:00:00

abstract：:In the adult brain, neural proliferation is almost absent and neurons are generally not renewed. By contrast, in the olfactory organ, olfactory neurons are produced continuously throughout life. To investigate whether specific cell cycle inhibitors are involved in the control of neural quiescence in adulthood, we comp...

journal_title：Neuroreport

authors： Legrier ME,Ducray A,Propper A,Kastner A

更新日期：2001-10-08 00:00:00

abstract：:The effects of Alzheimer's disease-related beta-amyloid (Abeta) peptides on the N-methyl-D-aspartate (NMDA)-evoked cell firing rate were studied in hippocampal CA1 neurons of the rat. Extracellular single-unit recordings were combined with iontophoretic applications that allowed quantitative analyses of the interactio...

journal_title：Neuroreport

authors： Molnár Z,Soós K,Lengyel I,Penke B,Szegedi V,Budai D

更新日期：2004-07-19 00:00:00

abstract：:Dichotic pitches and mistuned harmonics can each lead to the perception of one or two auditory objects. Comparison of event-related potentials for the perception of one versus two objects reveals an early negative and a late positive component. The relationship of these components with auditory segregation was further...

journal_title：Neuroreport

authors： Hautus MJ,Johnson BW,Colling LJ

更新日期：2009-07-01 00:00:00

abstract：:There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to the level of sentence syntax. Although birdsong can indeed have a complex structure, it lacks the combinatori...

journal_title：Neuroreport

authors： Beckers GJ,Bolhuis JJ,Okanoya K,Berwick RC

更新日期：2012-02-15 00:00:00

abstract：:Perception of apparent motion operates somewhat differently for objects and human figures. Depending on the interstimulus interval, the latter d may give rise to either perception of a direct path (i.e. biologically impossible) or indirect path (i.e. biologically possible). Here, PET was used to investigate whether a ...

journal_title：Neuroreport

authors： Stevens JA,Fonlupt P,Shiffrar M,Decety J

更新日期：2000-01-17 00:00:00

abstract：:Galanin, oxytocin and cholecystokinin (CCK) are peptides that influence feeding behaviour. Galanin has been found to stimulate food intake and oxytocin and CCK have been suggested to be satiety agents. The present study was performed in order to investigate if galanin influences the secretion of oxytocin and CCK as a ...

journal_title：Neuroreport

authors： Björkstrand E,Hulting AL,Meister B,Uvnäs-Moberg K

更新日期：1993-01-01 00:00:00

abstract：:Psychotic-like episodes in divers exposed to high pressure have been attributed to either the high-pressure neurological syndrome, confinement in pressure chamber, the subject's personality, or the addition of nitrogen or hydrogen to the basic helium-oxygen breathing mixture used for deep diving. Alternatively, it is ...

journal_title：Neuroreport

authors： Abraini JH

更新日期：1995-03-07 00:00:00

abstract：:Using fMRI, we observed cortical activity associated with nociceptive hot and cold sensations applied to hand and foot that are not spatially restricted to the corresponding regions of the primary somatosensory cortex (SI). Hot (55-57 degrees C) and cold (0-2 degrees C) tactile stimuli were applied separately to the r...

journal_title：Neuroreport

authors： Berman HH,Kim KH,Talati A,Hirsch J

更新日期：1998-12-21 00:00:00

abstract：:The spatial-temporal expression and function of Drosophila melanogaster homothorax (hth) and its vertebrate homologue Meis2 in the eye anlage show a high degree of evolutionary conservation. Both are expressed by progenitor cells ahead of the neurogenic wave front, promote rapid proliferation of these cells, and are d...

journal_title：Neuroreport

authors： Heine P,Dohle E,Schulte D

更新日期：2009-02-18 00:00:00