Central sensitization in medullary dorsal horn involves gap junctions and hemichannels.

abstract：:Sound localization can be affected by vision; in the ventriloquism effect, sounds that are hard to localize within hearing become mislocalized toward the location of concurrent visual events. Here we tested whether spatial attention is drawn to the illusory location of a ventriloquized sound. The study exploited our p...

journal_title：Neuroreport

authors： Spence C,Driver J

更新日期：2000-06-26 00:00:00

abstract：:Eleven early-onset dementia families, all with affected individuals who have either presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have been confirmed to have EOFAD by autopsy, and two early onset cases with biopsy-confirmed AD pathology, were screened for missense mutations in the ...

journal_title：Neuroreport

authors： Kwok JB,Taddei K,Hallupp M,Fisher C,Brooks WS,Broe GA,Hardy J,Fulham MJ,Nicholson GA,Stell R,St George Hyslop PH,Fraser PE,Kakulas B,Clarnette R,Relkin N,Gandy SE,Schofield PR,Martins RN

更新日期：1997-04-14 00:00:00

abstract：:Nogo-A, a member of the reticulon family, is one of the most important myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the central nervous system. RhoA has been targeted pharmacologically to promote neurite outgrowth and functional recovery in the brain and spinal cord. However, the und...

journal_title：Neuroreport

authors： Wang H,Shen J,Xiong N,Zhao H,Chen Y

更新日期：2011-10-26 00:00:00

abstract：:The distribution of activated NF-kappaB (p65) was studied in granule cells of the rat fascia dentata using confocal laser scanning microscopy and preembedding immunogold electron microscopy. Activated NF-kappaB, detected with a monoclonal antibody specific for the nuclear localization signal-epitope, was found in prox...

journal_title：Neuroreport

authors： Kaltschmidt B,Deller T,Frotscher M,Kaltschmidt C

更新日期：2000-03-20 00:00:00

abstract：:Both acute and chronic exercise is consistently associated with a number of benefits to physical and mental health, including cardiovascular function, body weight, mood, and cognition. Near-infrared spectroscopy is an ideal method to measure changes in oxygenated and deoxygenated hemoglobin (O2Hb and dHb) levels in th...

journal_title：Neuroreport

authors： Giles GE,Brunyé TT,Eddy MD,Mahoney CR,Gagnon SA,Taylor HA,Kanarek RB

更新日期：2014-11-12 00:00:00

abstract：:The aim of the study was to investigate differences in the distribution of intranasal trigeminal receptors in humans using an electrophysiological measure of trigeminally induced activation, the negative mucosa potential. A total of 29 young, healthy volunteers participated, results were on the basis of data from 18 p...

journal_title：Neuroreport

authors： Scheibe M,Zahnert T,Hummel T

更新日期：2006-09-18 00:00:00

abstract：:The objective of this study was to investigate the effects of long-term mental abacus calculation training (MACT) on children's spatial attention orientation. Fifteen children with intensive MACT (MACT group) and 15 children without MACT (non-MACT group) were selected. The two groups of children were matched in age, s...

journal_title：Neuroreport

authors： Liu X,Sun Y

更新日期：2017-01-01 00:00:00

abstract：:We have isolated a cDNA encoding an inwardly rectifying K+ channel (HH-IRK1) from human heart. The cDNA codes for a 427-amino acid protein, with two putative transmembrane domains and an H5 region. The primary structure of HH-IRK1 is homologous to that of the IRK1 channel cloned from a mouse macrophage-like cell line....

journal_title：Neuroreport

authors： Raab-Graham KF,Radeke CM,Vandenberg CA

更新日期：1994-12-20 00:00:00

abstract：:Chronic ethanol (EtOH) exposure can cause intracellular Ca overload by stimulating calcium channel receptors and trigger apoptosis of neurons. NCX3 may play a cytoprotective role in intracellular Ca excretion. In this study, the effect of EtOH on NCX3 was analyzed by observing NCX3 expression in the hippocampus of chr...

journal_title：Neuroreport

authors： Wang C,Wang X,Li Y,Xia Z,Liu Y,Yu H,Xu G,Wu X,Zhao R,Zhang G

更新日期：2019-04-10 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity reproduces many of the features of Parkinson's disease (PD). alpha-Synuclein has been identified as a prominent component of the Lewy body (LB), the pathological hallmark of PD. MPTP-treated primates have been reported to develop intraneuronal inclusion...

journal_title：Neuroreport

authors： Kowall NW,Hantraye P,Brouillet E,Beal MF,McKee AC,Ferrante RJ

更新日期：2000-01-17 00:00:00

abstract：:Dysfunctional glutamate neurotransmission has been implicated in the pathophysiology of schizophrenia. Abnormal expressions in schizophrenia of ionotropic glutamate receptors (iGluRs) and the proteins that regulate their trafficking have been found to be region and subunit specific in brain, suggesting that abnormal t...

journal_title：Neuroreport

authors： Tucholski J,Simmons MS,Pinner AL,McMillan LD,Haroutunian V,Meador-Woodruff JH

更新日期：2013-08-21 00:00:00

abstract：:Somatostatin sst2(a) receptor was observed, by immunofluorescence, in ependymal cells and in tanycytes of the wall of the ventricle and the hypothalamic recess of the male rat median eminence. Strong immunoreactivity for the receptor protein was observed in lateral tanycytes (alpha-type) while a moderate signal was se...

journal_title：Neuroreport

authors： Hashemi SH,Li JY,Schindler M,Dahlström A

更新日期：2001-07-03 00:00:00

abstract：:Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, how...

journal_title：Neuroreport

authors： Francl JM,Kaur G,Glass JD

更新日期：2010-11-17 00:00:00

abstract：:This study used event-related functional magnetic resonance imaging to investigate the neural basis underlying the sequential involvement of syntactic processing in the course of sentence comprehension. In experiments, a noun, case particle, and verb were presented one by one, constituting simple sentences in Japanese...

journal_title：Neuroreport

authors： Ogawa K,Ohba M,Inui T

更新日期：2007-09-17 00:00:00

abstract：:We studied whether 5-month-old to 8-month-old infants process faces in a size-invariant manner by applying the fNIRS-adaptation paradigm used in our previous study. We used near-infrared spectroscopy to measure hemodynamic responses in the temporal regions of infants' brains during the repeated presentation of an iden...

journal_title：Neuroreport

authors： Kobayashi M,Otsuka Y,Kanazawa S,Yamaguchi MK,Kakigi R

更新日期：2012-12-05 00:00:00

abstract：:DNA fragmentation, the hallmark of apoptosis, has been recently investigated with contradictory results in several skeletal muscle disorders. Using in situ labeling of nuclear DNA fragmentation, we have tested the possibility that apoptosis might occur in muscles from patients with mitochondrial respiratory chain defe...

journal_title：Neuroreport

authors： Monici MC,Toscano A,Girlanda P,Aguennouz M,Musumeci O,Vita G

更新日期：1998-07-13 00:00:00

abstract：:Expression of the lipophilic ligand transporter, apolipoprotein D (apoD) by primary astrocyte cultures derived from neonatal mouse brain was investigated. Western blot analysis of cell lysates and media showed that apoD is constitutively secreted by astrocytes with little intracellular storage. The secreted apoD float...

journal_title：Neuroreport

authors： Patel SC,Asotra K,Patel YC,McConathy WJ,Patel RC,Suresh S

更新日期：1995-03-07 00:00:00

abstract：:Using subtractive cloning, we identified a 1.4 kb mRNA that was ubiquitously expressed in various tissues; this mRNA was highly up-regulated in amygdala nuclei in mice when morphine was repeatedly administered but not when an opiate-receptor antagonist was co-administered. The mRNA encodes a 23 kDa protein, designated...

journal_title：Neuroreport

authors： Ikemoto MJ,Inoue K,Akiduki S,Osugi T,Imamura T,Ishida N,Ohtomi M

更新日期：2002-11-15 00:00:00

abstract：:Adult male hamsters and rats were reared for 2 months in either an isolated condition (IC) or a social condition (SC). The lengths of synaptic active zones (SAZ) of synapses in the granule cell layer of the accessory olfactory bulb were measured as an indicator of synaptic size in perforated and non-perforated synapse...

journal_title：Neuroreport

authors： Matsuoka M,Mori Y,Ichikawa M

更新日期：1996-10-02 00:00:00

abstract：:Secondary brain injury imposes great effects on the prognosis of patients following traumatic brain injury (TBI). Accumulating evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) could play a neuroprotective role in experimental TBI models by regulating the expression of numerous antioxidant, ant...

journal_title：Neuroreport

authors： He Y,Yan H,Ni H,Liang W,Jin W

更新日期：2019-03-20 00:00:00

abstract：:The present study examined in urethane-chloralose anaesthetized rats whether N-methyl-D-aspartate (NMDA) is involved in the depressant effect of flupirtine on the monosynaptic Hoffmann (H)-reflex recorded from plantar foot muscles and on polysynaptic flexor reflexes recorded from tibialis muscle. Intrathecal administr...

journal_title：Neuroreport

authors： Schwarz M,Block F,Pergande G

更新日期：1994-10-03 00:00:00

abstract：:The effects of a pharmacological blockade of the periaqueductal grey of the midbrain (PAG) on the elicitability of vocal fold movements from the facial motor cortex on the one hand and the anterior cingulate cortex and dorsomedial hypothalamus on the other were studied in the squirrel monkey. PAG blockade abolished vo...

journal_title：Neuroreport

authors： Jürgens U,Zwirner P

更新日期：1996-11-25 00:00:00

abstract：:Neurons respond to extracellular stimulation by modulating the expression of certain immediate-early genes. Inducible transcription factors (ITFs), such as c-Fos and Zif268, are coded by this class of gene and are among the first proteins to appear. The rapid accumulation of these products combined with histological m...

journal_title：Neuroreport

authors： Chaudhuri A

更新日期：1997-09-08 00:00:00

abstract：:We used fMRI to reveal the visual cortical activations during conventional or electro-acupuncture over four vision-implicated acupoints in 18 healthy volunteers and compared the results with those obtained during direct visual stimulation. Positive activations were seen over the visual cortex during visual stimulation...

journal_title：Neuroreport

authors： Li G,Cheung RT,Ma QY,Yang ES

更新日期：2003-04-15 00:00:00

abstract：:Lithium treatment lengthens the period of circadian rhythms in most organisms. In the present study, we tested whether lithium acts directly on the mammalian suprachiasmatic nucleus (SCN) to lengthen rhythms of individual neurons. Lithium increased the circadian period of firing rate rhythms of cultured SCN neurons in...

journal_title：Neuroreport

authors： Abe M,Herzog ED,Block GD

更新日期：2000-09-28 00:00:00

abstract：:The present study examined the distribution in the human spinal cord of a unique carboxy terminus sequence contained within MOR-1C, one of the recently described splice variants of the cloned mu opioid receptor gene MOR-1. Although MOR-1-like immunoreactivity (LI) and delta opioid receptor-like immunoreactivity were o...

journal_title：Neuroreport

authors： Abbadie C,Gultekin SH,Pasternak GW

更新日期：2000-06-26 00:00:00

abstract：:In the visual modality adaptation to high temporal frequency can result in spatially localized apparent duration compression. The principal point of adaptation is thought to be early in the visual system, at which point temporal information is encoded within sustained (parvocellular) and transient (magnocellular) chan...

journal_title：Neuroreport

authors： Watanabe J,Amemiya T,Nishida S,Johnston A

更新日期：2010-09-15 00:00:00

abstract：:It is widely accepted that prostaglandin (PG) E2 is the principal pro-inflammatory prostanoid and plays an important role in inflammatory pain. However whether PGE2 is involved in neuropathic pain remains unknown. PGE2 is produced from arachidonic acid via PGH2 by at least three PGE synthases (PGES), cytosolic PGES (c...

journal_title：Neuroreport

authors： Mabuchi T,Kojima H,Abe T,Takagi K,Sakurai M,Ohmiya Y,Uematsu S,Akira S,Watanabe K,Ito S

更新日期：2004-06-28 00:00:00

abstract：:Absence seizures are known to originate from disruptions within the corticothalamocortical network; however, the precise underlying cellular and molecular mechanisms that induce hypersynchronicity and hyperexcitability are debated and likely to be complex and multifactorial. Recent studies implicate impaired thalamic ...

journal_title：Neuroreport

authors： Seo S,Leitch B

更新日期：2017-12-13 00:00:00

abstract：:Regulation of CNS distribution of the human immunodeficiency virus (HIV) protease inhibitor saquinavir may involve ATP-dependent membrane-bound efflux transport proteins that are expressed in several brain cellular compartments. We recently characterized molecular and functional expression of one such transporter, mul...

journal_title：Neuroreport

authors： Dallas S,Ronaldson PT,Bendayan M,Bendayan R

更新日期：2004-05-19 00:00:00