Visual cortical activations on fMRI upon stimulation of the vision-implicated acupoints.

abstract：:The hypothesis of a general (i.e. cross-modal) temporal processing deficit in dyslexia was tested by examining rapid processing in both the auditory and the visual system in the same children with dyslexia. Participants were 10- to 12-year-old dyslexic readers and age-matched normal reading controls. Psychophysical th...

journal_title：Neuroreport

authors： Van Ingelghem M,van Wieringen A,Wouters J,Vandenbussche E,Onghena P,Ghesquière P

更新日期：2001-11-16 00:00:00

abstract：:Extrasynaptic transmission is mediated by the diffusion of transmitters, through the extracellular space (ECS) to receptors on neurons and glia. The three-dimensional diffusion of tetramethylammonium (mol. wt 74.1 kDa) was investigated in the isolated rat spinal cord at postnatal days 4-20. The diffusion parameters of...

journal_title：Neuroreport

authors： Prokopová S,Vargová L,Syková E

更新日期：1997-11-10 00:00:00

abstract：:We recorded auditory evoked magnetic fields (AEFs) by presenting pure tone bursts once every 4000 ms in 11 patients with a brain lesion in or in the vicinity of the auditory cortex. AEFs on the damaged side revealed several enhanced deflections in late-latency AEFs (slow AEFs), peaking at approximately 320 (DI), 1030 ...

journal_title：Neuroreport

authors： Kamada K,Takeuchi F,Harada T,Qiao B,Houkin K,Kuriki S,Iwasaki Y,Mitsumori K

更新日期：2001-05-08 00:00:00

abstract：:Hydrogen peroxide (H₂O₂) is a ubiquitous reactive oxygen species that can induce several inner ear disorders. In this study, we recorded the potassium (K) currents in acutely isolated inner hair cells of guinea pig cochlea, and investigated the effects of H₂O₂. We also observed the morphological changes in inner hair ...

journal_title：Neuroreport

authors： Kimitsuki T,Komune N,Noda T,Takaiwa K,Ohashi M,Komune S

更新日期：2010-11-17 00:00:00

abstract：:In marked contrast to several other species, including rats and humans, leptin gene expression is undetectable in mouse brain. This unexpected finding may reflect unique energy regulation pathways in the mouse. We investigated possible mechanisms by which leptin (ob) gene expression is suppressed in mouse brain: (a) t...

journal_title：Neuroreport

authors： Brown RE,Wilkinson DA,Wilkinson PM,Imran SA,Wilkinson M

更新日期：2012-10-24 00:00:00

abstract：:In Xenopus oocytes coinjected with poly(A)+ RNA derived from the rat cerebellum and cRNAs for the cloned G protein-gated inwardly rectifying K+ channel (GIRK), GIRK1 and GIRK2, the GABA-B agonist baclofen elicited inwardly rectifying K+ currents. The inward K+ currents elicited by baclofen were inhibited by the select...

journal_title：Neuroreport

authors： Uezono Y,Akihara M,Kaibara M,Kawano C,Shibuya I,Ueda Y,Yanagihara N,Toyohira Y,Yamashita H,Taniyama K,Izumi F

更新日期：1998-03-09 00:00:00

abstract：:As manifestations of prion diseases include disturbances of hypothalamic and pituitary functions, we tested the hypothesis that the cellular prion protein (PrPC) has a role as modulator of the hypothalamic-pituitary-adrenal axis. The level of corticosterone and adrenocorticotropic hormone were compared in PrPC null (P...

journal_title：Neuroreport

authors： Sanchez-Alavez M,Criado JR,Klein I,Moroncini G,Conti B

更新日期：2008-10-08 00:00:00

abstract：:Insulin-like growth factor (IGF)-I is essential for cerebellar granule neuron survival and a decline in IGF-I is implicated in various age-dependent processes. Here we show that IGF-I mRNA levels are decreased in the cerebellum of old rats compared with young rats and this was associated with increased cell death and ...

journal_title：Neuroreport

authors： Pañeda C,Arroba AI,Frago LM,Holm AM,Rømer J,Argente J,Chowen JA

更新日期：2003-08-26 00:00:00

abstract：:The 6-hydroxydopamine rat model of Parkinson's disease was combined with intracerebral drug infusions to examine the influence of glutamate receptors on striatal output activity. When infused into the dopamine-denervated striatum, the AMPA-kainate receptor antagonist DNQX dose-dependently elicited contralateral rotati...

journal_title：Neuroreport

authors： Schuller JJ,Marshall JF

更新日期：1995-12-15 00:00:00

abstract：:Sex differences in event-related potentials were examined in 23 women and 24 men during a mental rotation task. We found an early (130-400 ms) and a late (400-700 ms) ERP mental rotation effect. The late rotation effect, which is thought to indicate the onset of the cognitive process of mental rotation, emerged about ...

journal_title：Neuroreport

authors： Gootjes L,Bruggeling EC,Magnée T,Van Strien JW

更新日期：2008-02-12 00:00:00

abstract：:The distribution of GABA(B) receptor subunits GABA(B(1a)), GABA(B(1b)) and GABA(B2), has been examined in the cerebral cortex and thalamus of adult rats using an immunocytochemical technique. GABA(B(1a)) and GABA(B(1b)) subunits co-localized with GABA(B2) in the cortex, where afferent thalamic GABAergic axons project ...

journal_title：Neuroreport

authors： Princivalle AP,Pangalos MN,Bowery NG,Spreafico R

更新日期：2001-03-05 00:00:00

abstract：:A two-electrode voltage clamp was used to examine the effects of the local anaesthetics (LAs) lidocaine, tetracaine and bupivacaine, and the meta-isomer of lidocaine (LL33), on the gamma-aminobutyric acid (GABA)-gated Cl- channel in the crayfish stretch receptor neurone. The voltage-induced current changes were record...

journal_title：Neuroreport

authors： Nordmark J,Rydqvist B

更新日期：1997-01-20 00:00:00

abstract：:Clinical and experimental studies clearly demonstrate that prolonged seizures and status epilepticus induce neuronal cell death in the brain. Recent evidence suggests that induction of apoptosis contributes greatly to seizure-induced brain damage. We recently demonstrated that intrahippocampal delivery of botulinum ne...

journal_title：Neuroreport

authors： Manno I,Antonucci F,Caleo M,Bozzi Y

更新日期：2007-04-16 00:00:00

abstract：:In the adult brain, neural proliferation is almost absent and neurons are generally not renewed. By contrast, in the olfactory organ, olfactory neurons are produced continuously throughout life. To investigate whether specific cell cycle inhibitors are involved in the control of neural quiescence in adulthood, we comp...

journal_title：Neuroreport

authors： Legrier ME,Ducray A,Propper A,Kastner A

更新日期：2001-10-08 00:00:00

abstract：:In this study, an algorithm is introduced for the automatic detection and simultaneous topographic classification of interictal regional spike activity in pediatric surface EEG records. The algorithm is based on the classification of the topographic distribution of instantaneous power by means of a 'group' trained cla...

journal_title：Neuroreport

authors： Feucht M,Hoffmann K,Steinberger K,Witte H,Benninger F,Arnold M,Doering A

更新日期：1997-07-07 00:00:00

abstract：:When we perform a visually guided reaching action, the brain coordinates our hand and eye movements. Eye-hand coordination has been examined widely, but it remains unclear whether the hand and eye motor systems are coordinated during on-line visuomotor adjustments induced by a target jump during a reaching movement. A...

journal_title：Neuroreport

authors： Abekawa N,Inui T,Gomi H

更新日期：2014-05-07 00:00:00

abstract：:We examined the effect of an AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole) antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F) quinoxaline (NBQX), on rat cerebellar Purkinje cell loss and hippocampal pyramidal CA1 cell loss, after 10 minutes of global cerebral ischemia. NBQX was given intraperitoneally in a do...

journal_title：Neuroreport

authors： Balchen T,Diemer NH

更新日期：1992-09-01 00:00:00

abstract：:The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile...

journal_title：Neuroreport

authors： Bourisly AK

更新日期：2016-09-28 00:00:00

abstract：:Somatosensory evoked fields were recorded to determine the effects of movement and attention on high-frequency oscillations during active finger movements of the ipsilateral and contralateral sides in response to electrical stimulation of the median nerve. A whole-scalp neuromagnetometer was used to record somatosenso...

journal_title：Neuroreport

authors： Inoue K,Harada T,Kaseda Y,Mimori Y,Hashizume A,Hashimoto I,Matsumoto M

更新日期：2002-10-28 00:00:00

abstract：:The amyloid cascade hypothesis suggests that amyloid precursor protein (APP) proteolytic processing is a key event in the pathogenesis of Alzheimer's disease (AD). The enzymes beta-site APP cleaving enzyme (BACE) and A disintegrin and metalloproteinase 10 (ADAM10) play an important role in APP proteolysis. We measured...

journal_title：Neuroreport

authors： Gatta LB,Albertini A,Ravid R,Finazzi D

更新日期：2002-11-15 00:00:00

abstract：:Autism is a neurodevelopmental disorder characterized by preserved visual abilities as well as a special profile for visual cognition. We examined the visual cortex of high-ability individuals with autism in order to assess whether the presence of abnormalities at the primary sensory level in autism could be the basis...

journal_title：Neuroreport

authors： Hadjikhani N,Chabris CF,Joseph RM,Clark J,McGrath L,Aharon I,Feczko E,Tager-Flusberg H,Harris GJ

更新日期：2004-02-09 00:00:00

abstract：:To study the penetration of magnesium ions from blood into brain tissue, magnesium content in serum and hippocampus of normal and of excitotoxically affected rats was estimated after a single subcutaneous injection of magnesium sulphate (600 mg kg-1). In normal rats Mg2+ levels in serum rose from 1 to 6 mM, while that...

journal_title：Neuroreport

authors： Rothe F,Wolf G,Fischer S,Hass P,Keilhoff G,Abicht K

更新日期：1993-02-01 00:00:00

abstract：:DJ-1, originally identified as an oncogene product, is involved in multiple processes, including cellular transformation, the oxidative stress response, and transcriptional regulation. We had previously found that DJ-1 was closely associated with the proliferation and differentiation of cultured neuronal stem cells. I...

journal_title：Neuroreport

authors： Sun Y,Wang Y,Zhao X,Pu X

更新日期：2018-03-07 00:00:00

abstract：:The mixed-action κ-opioid receptor (KOR) agonist, pentazocine, binds to both KOR and the µ-opioid receptor (MOR). Racemic (±)-pentazocine and (-)-pentazocine, each administered systemically, have been shown to produce antinociception in various animal models. In contrast, racemic (±)-pentazocine failed to produce anti...

journal_title：Neuroreport

authors： Robinson DL Jr,Nag S,Mokha SS

更新日期：2018-07-04 00:00:00

abstract：:Spinally administered adenosine reduces hypersensitivity in animals and humans with nerve injury, but also causes transient pain in humans and reduces tonic inhibition in spinal neurons. Nerve injury results in increased tonic spinal cord adenosine A1 receptor activation, consistent with a role for adenosine to genera...

journal_title：Neuroreport

authors： Martin TJ,Eisenach JC,Misler J,Childers SR

更新日期：2006-10-23 00:00:00

abstract：:MicroRNAs (miRNAs) have been documented as critical regulators in ischemia/reperfusion-induced neuronal death. A better understanding of miRNA-mediated molecular mechanisms in ischemia/reperfusion-induced neuronal death may provide therapeutic targets for cerebral ischemia/reperfusion injury. A growing body of evidenc...

journal_title：Neuroreport

authors： Xiao J,Kong R,Hu J

更新日期：2018-06-13 00:00:00

abstract：:Two well-known appetite-regulatory peptides, leptin and cocaine- and amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet known how they interact in the nucleus accumbens, an important region mediating the rewarding effects of drugs of abuse. Using th...

journal_title：Neuroreport

authors： Cho BR,Yoon HS,Kim WY,Vezina P,Kim JH

更新日期：2017-08-02 00:00:00

abstract：:The study aimed to investigate the time-course of electromagnetic field (EMF)-induced effects on human cognitive and behavioral performance and on tympanic temperature. Subjects were randomly assigned to two groups, exposed to a 902.40 MHz EMF before the testing session, or to the same signal during the data collectin...

journal_title：Neuroreport

authors： Curcio G,Ferrara M,De Gennaro L,Cristiani R,D'Inzeo G,Bertini M

更新日期：2004-01-19 00:00:00

abstract：:We investigated the role of melatonin in the induction of gastric lesions induced by water immersion restraint stress or centrally administered thyrotropin-releasing hormone (TRH). Melatonin (0.1-1 ng) injected intracisternally (i.c) 30 min prior to stress dose-dependently inhibited the induction of gastric lesions by...

journal_title：Neuroreport

authors： Kato K,Murai I,Asai S,Komuro S,Matsuno Y,Matsukawa Y,Kurosaka H,Iwasaki A,Ishikawa K,Arakawa Y

更新日期：1997-07-07 00:00:00

abstract：:The mechanism by which IL-1 beta exerts its actions in the brain during systemic inflammation is not fully understood, as neither IL-1 receptor gene expression nor IL-1 binding have been identified in significant levels in key areas that respond to IL-1 beta. Having hypothesized that perivascular nitric oxide (NO) mig...

journal_title：Neuroreport

authors： Wong ML,Bongiorno PB,al-Shekhlee A,Esposito A,Khatri P,Licinio J

更新日期：1996-11-04 00:00:00