Abstract:
:Somatostatin sst2(a) receptor was observed, by immunofluorescence, in ependymal cells and in tanycytes of the wall of the ventricle and the hypothalamic recess of the male rat median eminence. Strong immunoreactivity for the receptor protein was observed in lateral tanycytes (alpha-type) while a moderate signal was seen in medial tanycytes (beta-type). In high magnification the immunoreactive material, of moderate intensity, had a coarse granular appearance. Only few of the alpha-tanycytes also displayed immunoreactive GFAP. The apical portion of the ependymal cells as well as of tanycytes contained immunoreactive S-100 (alphabeta). Since rather high levels of somatostatin are demonstrated to occur in the cerebrospinal fluid of the third ventricle, it is suggested that somatostatin via the sst2(a) receptor may regulate the physiology of tanycytes.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Hashemi SH,Li JY,Schindler M,Dahlström Adoi
10.1097/00001756-200107030-00007subject
Has Abstractpub_date
2001-07-03 00:00:00pages
1793-7issue
9eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Intraplantar carrageenan induced a peripheral oedema and c-Fos like immunoreactivity (Fos-LI) in L4-L5 segments in the dorsal horn (DH) of the rat spinal cord. The total number of carrageenan evoked Fos-LI neurones was 153 +/- 10 per section, with a predominant localization in the superficial and deep laminae of the D...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199507100-00006
更新日期:1995-07-10 00:00:00
abstract::Altered glutamate signaling is associated with Parkinson's disease. To study the involvement of the cystine/glutamate antiporter in the pathogenesis of Parkinson's disease, we developed new polyclonal antibodies recognizing xCT, the specific subunit of this antiporter. The striatal xCT protein expression level was inv...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328312181c
更新日期:2008-10-29 00:00:00
abstract::Dichotic pitches and mistuned harmonics can each lead to the perception of one or two auditory objects. Comparison of event-related potentials for the perception of one versus two objects reveals an early negative and a late positive component. The relationship of these components with auditory segregation was further...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32832c92bf
更新日期:2009-07-01 00:00:00
abstract::This study was carried out based on the assumption that brain-derived neurotrophic factor (BDNF) may counterbalance the action of morphine in the brain. Morphine analgesic tolerance after daily administrations for six days was blocked by intracerebroventricular injection of anti-BDNF IgG on day 5, but not by administr...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328314decb
更新日期:2009-01-07 00:00:00
abstract::Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283405bad
更新日期:2010-12-08 00:00:00
abstract::In this study, the brainstem-spinal cord preparation isolated from newborn rats, an established model for the study of the hypoxic respiratory depression (HRD), has been used. The comparison of Fos expression in ponto-medullary areas in these preparations placed either in normoxic or hypoxic conditions suggests that o...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200112210-00012
更新日期:2001-12-21 00:00:00
abstract::Prepulse inhibition (PPI) of the acoustic startle reflex is a measure of sensorimotor gating which occurs in both rodents and humans. PPI is deficient in severe neuropsychiatric disorders such as schizophrenia. We investigated PPI in 10 adult monkeys (Cebus apella). Stimuli were 115 dB white noise startle pulses, eith...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200101220-00031
更新日期:2001-01-22 00:00:00
abstract::It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this s...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283294a2f
更新日期:2009-04-22 00:00:00
abstract::Spinal cord injury (SCI) causes motor dysfunction and depression, which hinders the recovery of motor function. Body weight-supported treadmill training (BWSTT) should be considered an effective method for functional rehabilitation after SCI, as it is an efficacious intervention in healthcare with no side effects. Bec...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001543
更新日期:2020-12-16 00:00:00
abstract::It remains an open question whether the amplitude of N400 reflects combinatory postlexical semantic integration processing. To examine the issue, we repeatedly presented strictly simplified, N400-eliciting three-word structures for seven times, mixed with their plausible counterparts, followed immediately by a much mo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001108
更新日期:2018-11-07 00:00:00
abstract::In the adult brain, neural proliferation is almost absent and neurons are generally not renewed. By contrast, in the olfactory organ, olfactory neurons are produced continuously throughout life. To investigate whether specific cell cycle inhibitors are involved in the control of neural quiescence in adulthood, we comp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200110080-00029
更新日期:2001-10-08 00:00:00
abstract::Aging and Alzheimer's disease (AD) are both characterized by memory impairments and sleep changes. We investigated the potential link between these disturbances, focusing on sleep spindles, involved in memory consolidation. Two episodic memory tasks were given to young and old healthy participants, as well as to AD pa...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32830867c4
更新日期:2008-07-16 00:00:00
abstract::Amyloid precursor protein binding protein-1 (APP-BP1) was first identified as an interacting protein of APP. In this study, we explored whether APP-BP1 plays a role in neuronal differentiation of fetal neural stem cells. APP-BP1 knockdown by small interfering RNA treatment was found to downregulate neuronal differenti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32834e7d4f
更新日期:2012-01-25 00:00:00
abstract::We show that the pro-apoptotic proteins Bax and Bak trigger apoptosis when over-expressed in sympathetic neurons cultured in the presence of NGF. This effect can be blocked with z-VAD-fmk, a peptide inhibitor of caspases, but not with anti-apoptotic chemical compounds such as antioxidants or proteasome inhibitors. The...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199801050-00004
更新日期:1998-01-05 00:00:00
abstract::The protein p42(IP4) (also called centaurin alpha), identified as a brain-specific InsP4/PtdInsP3 (PIP3)-binding protein, has been shown to be localized in human brain, specifically expressed in neurons. Several casein kinases have been found to be involved in Alzheimer's disease (AD) pathology. Since casein kinase I ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200212200-00008
更新日期:2002-12-20 00:00:00
abstract::The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of all...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199607080-00030
更新日期:1996-07-08 00:00:00
abstract::Two groups of hemiparkinsonian rats received grafts of embryonic ventral mesencephalon with or without the addition of the NMDA receptor antagonist (+)dizocilpine hydrogen maleate (MK-801). When added to the cell suspension, a 10 microM concentration of MK-801 did not enhance the survival of tyrosine hydroxylase posit...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199805110-00011
更新日期:1998-05-11 00:00:00
abstract::We investigated the effects of radio frequency electromagnetic fields on brain physiology. Twenty-four healthy young men were exposed for 30 min to pulse-modulated or continuous-wave radio frequency electromagnetic fields (900 MHz; peak specific absorption rate 1 W/kg), or sham exposed. During exposure, participants p...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/WNR.0b013e3280d9435e
更新日期:2007-05-28 00:00:00
abstract::Alpha oscillations during cognitive performance have mostly been studied in memory and/or basic attention tasks. This study investigates task-related alpha power desynchronization during an attentional switching task requiring higher executive attentional control. Low 8-10 Hz and high 10-12 Hz alpha power responses ar...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200204160-00029
更新日期:2002-04-16 00:00:00
abstract::The purpose of the present study was to determine the cortical areas contributing to the influence of the previous movement on the current movement. Right-handed healthy human participants abducted and then adducted the left index finger in response to a start cue. Twenty consecutive trials with 10 s intertrial interv...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001578
更新日期:2020-12-30 00:00:00
abstract::Methamphetamine (METH)-induced dopaminergic neurotoxicity is associated with hyperthermia. We investigated the effect of several neuronal nitric oxide synthase (nNOS) inhibitors on METH-induced hyperthermia and striatal dopaminergic neurotoxicity. Administration of METH (5 mg/kg; q. 3 h x 3) to Swiss Webster mice prod...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200009110-00022
更新日期:2000-09-11 00:00:00
abstract::Hypoxic-ischemic brain damage (HIBD) occurs due to intrauterine hypoxia ischemia influencing the energy supply for fetal brain cells, which affects the metabolism of the brain to make the brain suffer a severe damage. Erythropoietin (EPO), which regulates hemacytopoiesis, is a kind of cytokine. EPO is sensitive to hyp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001194
更新日期:2019-03-06 00:00:00
abstract::The present study examines whether or not prolactin-releasing peptide (PrRP) infused intracerebroventricularly (i.c.v.) affects sleep and the release of prolactin (PRL) and growth hormone (GH) in rats. At a dose of 0.1 nmol, PrRP promoted rapid-eye-movement (REM) sleep, whereas 1.0 nmol increased both non-REM and REM ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200110290-00006
更新日期:2001-10-29 00:00:00
abstract::The functions of the fields of the mammalian auditory cortex in sound perception and recognition are unknown. We used Fos (a protein of the inducible immediate-early gene c-fos) as a cellular marker of activated brain areas to show in the mouse (Mus domesticus) that sound is processed differentially in auditory cortic...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199908020-00022
更新日期:1999-08-02 00:00:00
abstract::The distribution of PKCepsilon and its co-localization with various GABA(A) receptor subunits within limbic structures of the mouse brain was examined by fluorescence immunohistochemistry. Levels of PKCepsilon immunoreactivity were highest in the cingulate cortex and dentate gyrus, moderate in the nucleus accumbens, a...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200003200-00006
更新日期:2000-03-20 00:00:00
abstract::Previous studies have established a role for N-methyl-D-aspartate receptor (NMDAR) containing the GluN2B subunit in efficient learning behavior on a variety of tasks. Recent findings have suggested that NMDAR on GABAergic interneurons may underlie the modulation of striatal function necessary to balance efficient acti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000373
更新日期:2015-06-17 00:00:00
abstract::NCAM-180 knockout mice, which have documented deficits in neural migration, were used to determine whether developmental abnormalities could lead to morphological changes and alterations in sensory motor gating mechanisms. Measurement of the lateral ventricle showed that NCAM-180-/- mice had marked increases in both t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199802160-00019
更新日期:1998-02-16 00:00:00
abstract::We investigated whether short-term saccadic adaptation modifies hand pointing. Subjects were presented with double-step targets, the second target jump occurring during the saccade to the first one and bringing the target back to 66% of the first target eccentricity, in order to reduce the gain of their gaze saccades....
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199509000-00007
更新日期:1995-09-11 00:00:00
abstract::ONO-1714, a selective inhibitor of inducible nitric oxide synthetase (iNOS) attenuated the increase of apoptosis and improved the functional outcome of urinary bladder after traumatic spinal cord injury. These findings suggest that iNOS plays a role in the process of SCI. Early treatment with 30 mg/kg methylprednisolo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200409150-00021
更新日期:2004-09-15 00:00:00
abstract::Bioelectric activity of CO2-sensitive, ventrolateral medullary neurons (VLN(CS)) in organotypic cultures from the obex level of newborn rats was tested during changes of the intracellular pH (pHi) measured in BCECF-AM loaded cultures. Hypercapnia (pCO2 80-100 mmHg) reduced pHi by 0.15 +/- 0.06 units and stimulated neu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199801050-00034
更新日期:1998-01-05 00:00:00