Amyloid precursor protein binding protein-1 knockdown reduces neuronal differentiation in fetal neural stem cells.

abstract：:We investigated the expression for fibroblast growth factor-2 (FGF-2), in cultured rat cerebellar granule cells and its modulation by Ca2+ regulating agents. There were no significant differences in the levels of FGF-2 mRNA in cells cultured in high vs low K+. The expression of the trophic factor is induced by Ca2+ en...

journal_title：Neuroreport

authors： Roceri M,Molteni R,Racagni G,Riva MA

更新日期：2000-11-09 00:00:00

abstract：:ONO-1714, a selective inhibitor of inducible nitric oxide synthetase (iNOS) attenuated the increase of apoptosis and improved the functional outcome of urinary bladder after traumatic spinal cord injury. These findings suggest that iNOS plays a role in the process of SCI. Early treatment with 30 mg/kg methylprednisolo...

journal_title：Neuroreport

authors： Yu Y,Matsuyama Y,Nakashima S,Yanase M,Kiuchi K,Ishiguro N

更新日期：2004-09-15 00:00:00

abstract：:In addition to the study of pathological conditions, magnetic resonance spectroscopy can provide useful information about brain-behavior relationships in normal subjects. Recently, there have been reports of correlations between N-acetylaspartate (NAA) values and cognitive functions in normal adults. We tested the pos...

journal_title：Neuroreport

authors： Giménez M,Junqué C,Narberhaus A,Caldú X,Segarra D,Vendrell P,Bargalló N,Mercader JM

更新日期：2004-03-22 00:00:00

abstract：:The glomerular layer of the olfactory bulb contains a substantial population of dopaminergic neurons. We determined the quantity and location of D1 and D2 dopamine receptors which are the presumed targets of these neurons. Binding of the D1 selective ligand [3H]SCH23390 was slightly above background and was distribute...

journal_title：Neuroreport

authors： Nickell WT,Norman AB,Wyatt LM,Shipley MT

更新日期：1991-01-01 00:00:00

abstract：:We determined whether acute compensatory feeding pattern changes after bulbectomy persist on a chronic basis, or whether physiological adaptation occurs to normalize acute changes. Rats were randomized to olfactory bulbectomy or sham operation; all had jugular vein catheterization. Food intake, meal number and size we...

journal_title：Neuroreport

authors： Meguid MM,Koseki M,Yang ZJ,Gleason JR,Laviano A

更新日期：1997-04-14 00:00:00

abstract：:The relationship between cerebral ischemia and Alzheimer's disease has been evaluated extensively. However, the association between cerebral ischemia and the deposition of beta-amyloid (Abeta) remains to be clarified. Here, we used mice bilateral common carotid artery ligation model to investigate the alterations in m...

journal_title：Neuroreport

authors： Ye JT,Pi RB,Mao XX,Chen XH,Qin J,Xu SW,Liu PQ

更新日期：2009-10-28 00:00:00

abstract：:We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and B6 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels...

journal_title：Neuroreport

authors： Kurth C,Wegerer V,Reulbach U,Lewczuk P,Kornhuber J,Steinhoff BJ,Bleich S

更新日期：2004-02-09 00:00:00

abstract：:Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD) yet inconsistencies in activation have been reported. One source of variance are individual differences in 5-HTTLPR genotype where the short (S), relative to long (L) allele, corresponds with greater amygdala activation. Howe...

journal_title：Neuroreport

authors： Klumpp H,Fitzgerald DA,Cook E,Shankman SA,Angstadt M,Phan KL

更新日期：2014-08-20 00:00:00

abstract：:Delayed neuronal death induced by transient forebrain ischemia in the rat hippocampus is preceded by a prominent microglial reaction which begins within minutes after the ischemic injury. In the present study we have examined the effect of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 on m...

journal_title：Neuroreport

authors： Streit WJ,Morioka T,Kalehua AN

更新日期：1992-02-01 00:00:00

abstract：:Cortical processes underlying perception of musical consonance were investigated by long-latency auditory evoked potentials (EPs). Subjects listened to a random sequence of dyadic pure tones paired at various pitch intervals (1, 4, 6, 7, or 9 semitones). Amplitudes of P2 and N2 components of auditory EPs were signific...

journal_title：Neuroreport

authors： Itoh K,Suwazono S,Nakada T

更新日期：2003-12-19 00:00:00

abstract：:Voltage-gated K+ channels (K(V)) regulate cell electrical properties, proliferation, migration, and death. Rotenone is a mitochondrial inhibitor, influencing activity of many channels that potentially participate in cell death processes, but its effect on K(V) channel in neurons remains unclear. This study used whole-...

journal_title：Neuroreport

authors： Gao XF,Wang W,He C

更新日期：2008-09-17 00:00:00

abstract：:The present study explored duration mismatch negativity (MMN) reduction in schizophrenia. Duration MMN studies usually employ tones of very short duration (< 200 ms). For stimuli < 200 ms in duration, an increment in duration is accompanied by an increase in perceived loudness. It was previously proposed that the effe...

journal_title：Neuroreport

authors： Todd J,Michie PT,Jablensky AV

更新日期：2001-12-21 00:00:00

abstract：:We used multiple-labelling immunofluorescence, intracellular dye injection, electrophysiological recording and confocal microscopy to examine the expression of immunoreactivity to protein kinase C (PKC) and protein kinase A (PKA) in sympathetic ganglia of guinea-pigs. PKCalpha and PKCgamma were widespread in vasoconst...

journal_title：Neuroreport

authors： Gibbins IL,Matthew SE,Jobling P

更新日期：1999-04-06 00:00:00

abstract：:Direct currents (DC) applied directly to central nervous system structures produce substantial and long-lasting effects in animal experiments. We tested the functional effects of very weak scalp DC (< 0.5 mA, 7 s) on the human motor cortex by assessing the changes in motor potentials evoked by transcranial magnetic br...

journal_title：Neuroreport

authors： Priori A,Berardelli A,Rona S,Accornero N,Manfredi M

更新日期：1998-07-13 00:00:00

abstract：:Calpain activation has been implicated in the pathogenesis of Alzheimer's disease. Okadaic acid, a protein phosphatase-2A inhibitor, has been used in Alzheimer's disease research models to increase tau phosphorylation and induce neuronal death. We previously reported that okadaic acid induced predominant activation of...

journal_title：Neuroreport

authors： Yoon S,Choi J,Huh JW,Hwang O,Kim D

更新日期：2006-05-15 00:00:00

abstract：:This study describes gamma-imaging of the secondary tumors from the transplanted human fetal striatum neural stem cells-derived primary tumor cells in nude mice. The subcutaneous primary tumors were detected to express integrin alphavbeta3, and the corresponding cells were isolated and enriched in vitro, then transpla...

journal_title：Neuroreport

authors： He Q,Liu Z,Jia B,Li X,Shi J,Zhang J,Lan F,Yang Z,Liu Y,Shen L,Wang F

更新日期：2008-07-02 00:00:00

abstract：:Neuregulins (NRG), the only trophic factors known to support Schwann cell survival, have a potential for use in treatment of patients with chronic neuropathies. Expression of one NRG isoform, NRG-beta1, was increased in axons in the early phase of axonal degeneration in nerve biopsy specimens from patients with neurop...

journal_title：Neuroreport

authors： Oka N,Kawasaki T,Matsui M,Tachibana H,Sugita M,Akiguchi I

更新日期：2000-11-27 00:00:00

abstract：:Models of corticostriatal motor circuitry have focused on the role of the circuit in the hemisphere of the motor cortex providing primary control (contralateral to the movement). We used functional magnetic resonance imaging and functional connectivity analyses to study circuit function in both the controlling and non...

journal_title：Neuroreport

authors： Marchand WR,Lee JN,Thatcher JW,Hsu EW,Rashkin E,Suchy Y,Chelune G,Starr J,Barbera SS

更新日期：2008-06-11 00:00:00

abstract：:Sex differences in event-related potentials were examined in 23 women and 24 men during a mental rotation task. We found an early (130-400 ms) and a late (400-700 ms) ERP mental rotation effect. The late rotation effect, which is thought to indicate the onset of the cognitive process of mental rotation, emerged about ...

journal_title：Neuroreport

authors： Gootjes L,Bruggeling EC,Magnée T,Van Strien JW

更新日期：2008-02-12 00:00:00

abstract：:Hypoxia-inducible factor-1 (HIF-1) regulates the expression of neuroprotective genes such as erythropoietin (EPO). We investigated the mechanism by which zinc, an excitotoxin-like metal, regulates HIF-1 under hypoxic conditions in astrocytes. In hypoxic LN215 cells, HIF-1alpha stabilized and accumulated in the nucleus...

journal_title：Neuroreport

authors： Kim I,Kim CH,Seo GH,Kim HS,Lee J,Kim DG,Ahn YS

更新日期：2008-07-02 00:00:00

abstract：:The majority of retinal ganglion cells innervating the suprachiasmatic nucleus are intrinsically light sensitive, while the rest are conventional ganglion cells that collect inputs through conventional photoreceptors. Here we report a rarely encountered ganglion cell that had a dendritic field covering approximately 1...

journal_title：Neuroreport

authors： Pu M,Chen B,Li RS,Tay D,So KF

更新日期：2006-10-02 00:00:00

abstract：:We report the results of serial transcranial magnetic stimulation mapping of cortical motor outputs to the face and upper extremity in a subject studied before and repeatedly after traumatic amputation of the right arm immediately below the elbow. The results of the mapping studies illustrate the time course of plasti...

journal_title：Neuroreport

authors： Pascual-Leone A,Peris M,Tormos JM,Pascual AP,Catalá MD

更新日期：1996-09-02 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:When a food is eaten to satiety, its reward value decreases. This decrease is usually greater for the food eaten to satiety than for other foods, an effect termed sensory-specific satiety. In an fMRI investigation it was shown that for a region of the orbitofrontal cortex the activation produced by the odour of the fo...

journal_title：Neuroreport

authors： O'Doherty J,Rolls ET,Francis S,Bowtell R,McGlone F,Kobal G,Renner B,Ahne G

更新日期：2000-03-20 00:00:00

abstract：:In this experiment, event-related potentials were used to examine whether the neural correlates of encoding processes predicting subsequent successful recall differed from those predicting successful source memory retrieval. During encoding, participants studied lists of words and were instructed to memorize each word...

journal_title：Neuroreport

authors： Angel L,Isingrini M,Bouazzaoui B,Fay S

更新日期：2013-03-06 00:00:00

abstract：:Single unit recordings were made from the ventral posterior lateral thalamus of anaesthetized rats to characterize responses to the activation of new receptive fields induced by either local anaesthesia or amputation. Receptive fields confined to single digits were identified and evoked unit responses to the stimulati...

journal_title：Neuroreport

authors： Shin HC,Park S,Son J,Sohn JH

更新日期：1995-12-29 00:00:00

abstract：:To test the effect of nitric oxide synthase (NOS) blockade on the ventilatory responses to carotid body chemoreceptor stimulation in freely behaving animals, chronically instrumented adult Sprague-Dawley rats received increasing intravenous doses of sodium cyanide (NaCN; 0-300 micrograms kg-1) before and after i.v. ad...

journal_title：Neuroreport

authors： Gozal D,Gozal E,Gozal YM,Torres JE

更新日期：1996-04-26 00:00:00

abstract：:In the retina, the activation of metabotropic glutamate receptors (mGluRs) reduces the toxic effect of N-methyl-D-aspartate (NMDA). We have induced NMDA-mediated excitotoxicity in the adult rat retina by a single intraocular injection of NMDA. The damage that resulted was estimated by assessing the NMDA-induced loss o...

journal_title：Neuroreport

authors： Siliprandi R,Lipartiti M,Fadda E,Arban R,Kozikowski AP,Manev H

更新日期：1994-06-02 00:00:00

abstract：:Children with mathematical difficulties usually have an impaired ability to process symbolic representations. Functional MRI methods have suggested that early frontoparietal connectivity can predict mathematic achievements; however, the study of brain connectivity during numerical processing remains unexplored. With t...

journal_title：Neuroreport

authors： Gómez-Velázquez FR,Vélez-Pérez H,Espinoza-Valdez A,Romo-Vazquez R,Salido-Ruiz RA,Ruiz-Stovel V,Gallardo-Moreno GB,González-Garrido AA,Berumen G

更新日期：2017-02-08 00:00:00

abstract：:We compared various measures of visual-vestibular interaction in subjects with insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM), as well as non-diabetic controls. Subjects with IDDM exhibited significantly greater postural sway than controls on those conditions in the Clini...

journal_title：Neuroreport

authors： Darlington CL,Erasmus J,Nicholson M,King J,Smith PF

更新日期：2000-02-28 00:00:00