Polarization of the human motor cortex through the scalp.

abstract：:The first step in olfactory transduction is the recognition of odor molecules by membrane bound receptors belonging to the superfamily of G-protein coupled receptors; other members of this family are involved in neurotransmission. Based on the considerable homology between individual members of this family, we have in...

journal_title：Neuroreport

authors： Firestein S,Shepherd GM

更新日期：1992-08-01 00:00:00

abstract：:Thyroid hormone receptor beta2 (TRbeta2) controls the patterning of cone opsin photopigments that mediate colour vision. We raised an antiserum against TRbeta2 to study cone photoreceptor development by western blot and immunostaining analyses. TRbeta2-positive cells first appeared between embryonic day 10 (E10) and E...

journal_title：Neuroreport

authors： Ng L,Ma M,Curran T,Forrest D

更新日期：2009-04-22 00:00:00

abstract：:Event-related potential (ERP) studies have shown that responses to illusory (IC), as compared to no contours (NC), may differ within 200 ms following stimulus presentation. However, whether these responses reflect the modulation of similar, or the activation of distinct brain regions has never been assessed. Using ERP...

journal_title：Neuroreport

authors： Pegna AJ,Khateb A,Murray MM,Landis T,Michel CM

更新日期：2002-05-24 00:00:00

abstract：:Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-deliv...

journal_title：Neuroreport

authors： Ichihara-Takeda S,Takeda K,Funahashi S

更新日期：2010-03-31 00:00:00

abstract：:In the present study, the activity changes of chicken retinal ganglion cells in response to light stimuli with defined contrast were investigated, in the presence of various levels of sustained background illumination. Following a step increase of light illumination, the firing rate of most retinal ganglion cells incr...

journal_title：Neuroreport

authors： Chen AH,Zhou Y,Gong HQ,Liang PJ

更新日期：2005-03-15 00:00:00

abstract：:We determined whether acute compensatory feeding pattern changes after bulbectomy persist on a chronic basis, or whether physiological adaptation occurs to normalize acute changes. Rats were randomized to olfactory bulbectomy or sham operation; all had jugular vein catheterization. Food intake, meal number and size we...

journal_title：Neuroreport

authors： Meguid MM,Koseki M,Yang ZJ,Gleason JR,Laviano A

更新日期：1997-04-14 00:00:00

abstract：:Increasing evidence suggests that dynein has an important role in the clearance of misfolded proteins by autophagy. Here we show that treatment of cells with 1-methyl-4-phenylpyridinium (MPP) cause alpha-synuclein overexpression and aggregation, leading to the accumulation of autophagic vacuoles and the recruitment of...

journal_title：Neuroreport

authors： Cai ZL,Shi JJ,Yang YP,Cao BY,Wang F,Huang JZ,Yang F,Zhang P,Liu CF

更新日期：2009-04-22 00:00:00

abstract：:Amyloid precursor protein binding protein-1 (APP-BP1) was first identified as an interacting protein of APP. In this study, we explored whether APP-BP1 plays a role in neuronal differentiation of fetal neural stem cells. APP-BP1 knockdown by small interfering RNA treatment was found to downregulate neuronal differenti...

journal_title：Neuroreport

authors： Hong BH,Ha S,Joo Y,Kim JA,Chang KA,Woo RS,Suh YH,Kim JH,Kim HS

更新日期：2012-01-25 00:00:00

abstract：:The temperature of the tail skin is an important factor determining tail-flick latency to noxious radiant heat in rats and mice. The temperature of the skin may also be important in determining the behavioural response in the formalin test. Morphine in low and moderate doses strongly affected the core and tail skin te...

journal_title：Neuroreport

authors： Tjølsen A,Hole K

更新日期：1992-06-01 00:00:00

abstract：:Reorganization of motor execution and imagination networks was studied in six patients with unilateral dystonia secondary to a subcortical stroke and compared with seven control subjects using fMRI. Patients performed imagined and real auditory-cued hand movements. Movements of the dystonic hand resulted in overactivi...

journal_title：Neuroreport

authors： Lehéricy S,Gerardin E,Poline JB,Meunier S,Van de Moortele PF,Le Bihan D,Vidailhet M

更新日期：2004-08-26 00:00:00

abstract：:The effects of intracerebroventricular (i.c.v.) administration of galanin on plasma growth hormone (GH) concentrations and its possible mechanism of action have been examined in sheep. Galanin administration icv resulted in a dose-dependent increase in plasma GH concentrations (p < 0.01). Concurrent administration of ...

journal_title：Neuroreport

authors： Spencer GS,Berry CJ,Bass JJ

更新日期：1994-01-12 00:00:00

abstract：:Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg mo...

journal_title：Neuroreport

authors： Sharpe LG,Jaffe JH

更新日期：1990-09-01 00:00:00

abstract：:We examined whether 53 adult non-aphasic patients with either left (22) or right temporal lobe lesions (31) demonstrate dissociable patterns of hemispheric asymmetries in category-specific word fluency tasks. The patients were asked to articulate as many appropriate words as possible within 60 or 90 s in response to s...

journal_title：Neuroreport

authors： Jokeit H,Heger R,Ebner A,Markowitsch HJ

更新日期：1998-07-13 00:00:00

abstract：:S100B is a calcium binding protein from astrocytes that regulates protein phosphorylation by binding to substrates and protein kinases. S100B might also regulate protein phosphatases and this was investigated for protein phosphatase 2B (calcineurin). The results indicate that S100B (5-10 microM) increased the activity...

journal_title：Neuroreport

authors： Leal RB,Frizzo JK,Tramontina F,Fieuw-Makaroff S,Bobrovskaya L,Dunkley PR,Gonçalves CA

更新日期：2004-02-09 00:00:00

abstract：:Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

journal_title：Neuroreport

authors： Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

更新日期：1999-01-18 00:00:00

abstract：:Bulbospinal C1 neurons are sympathoexcitatory and excited by substance P. However the substance P receptor (NK1 receptor), has been reported to be absent from the somata of C1 neurons. In this study, using double and triple labelling immunofluorescence and retrograde tracing, we provide evidence that the NK1 receptor ...

journal_title：Neuroreport

authors： Makeham JM,Goodchild AK,Pilowsky PM

更新日期：2001-12-04 00:00:00

abstract：:Adenovirus vectors containing a marker gene (lacZ from Escherichia coli) are potent for transferring the gene to neurones after intraparenchymal injections. Expression of the marker gene may lead to the synthesis of an enormous amount of beta-galactosidase which diffuses throughout the entire neurone, providing a 'Gol...

journal_title：Neuroreport

authors： Lisovoski F,Cadusseau J,Akli S,Caillaud C,Vigne E,Poenaru L,Stratford-Perricaudet L,Pericaudet M,Kahn A,Peschanski M

更新日期：1994-05-09 00:00:00

abstract：:Müller cells, as the predominant glial element in the sensory retina, play a crucial role in healthy and diseased retina. Overactivation of Müller cells in response to damage is detrimental to the retina tissue. Current research shows that inhibiting glial fibrillary acidic protein (GFAP), a sensitive indicator of Mül...

journal_title：Neuroreport

authors： Wang X,Shu Q,Ni Y,Xu G

更新日期：2018-12-05 00:00:00

abstract：OBJECTIVE:Birdsong sounds are often used to inform visually-challenged people about the presence of basic infrastructures, and therefore need to be salient in noisy urban environments. How salient sounds are processed in the brain could inform us about the optimal birdsong in such environments. However, brain activity ...

journal_title：Neuroreport

authors： Yano H,Soeta Y

更新日期：2021-01-13 00:00:00

abstract：:Inflammatory and immune responses are known to be involved in the pathogenesis of Alzheimer's disease (AD). NF-kappaB is a major transcription factor that plays a central role in the inflammatory and immune responses and is regulated by I-kappaB through an autoregulatory feedback system. Southwestern immunohistochemis...

journal_title：Neuroreport

authors： Yoshiyama Y,Arai K,Hattori T

更新日期：2001-08-28 00:00:00

abstract：:The whole-cell patch clamp technique was used to investigate the actions of the opioid agonist U50488H on Ca2+ and K+ currents in differentiated NG108-15 cells. U50488H (5-50 microM) caused a concentration-dependent, reversible inhibition of high voltage-activated Ca2+ currents which persisted in the presence of nifed...

journal_title：Neuroreport

authors： Carpenter E,Gent JP,Peers C

更新日期：1996-07-29 00:00:00

abstract：:Event-related brain potential studies show that negative feedback in guessing tasks elicits a medial frontal negativity. Most theory and experimentation concerning this feedback-related negativity (FRN) has assumed that the FRN has little relationship to the perceptual characteristics of the feedback. This study chall...

journal_title：Neuroreport

authors： Liu Y,Gehring WJ

更新日期：2009-04-22 00:00:00

abstract：:NCAM-180 knockout mice, which have documented deficits in neural migration, were used to determine whether developmental abnormalities could lead to morphological changes and alterations in sensory motor gating mechanisms. Measurement of the lateral ventricle showed that NCAM-180-/- mice had marked increases in both t...

journal_title：Neuroreport

authors： Wood GK,Tomasiewicz H,Rutishauser U,Magnuson T,Quirion R,Rochford J,Srivastava LK

更新日期：1998-02-16 00:00:00

abstract：:We used two developmental transcription factors, x-Eomes (T-box family) and x-Lhx5 (LIM-homeodomain family), to follow the origin and development of the olfactory bulbs in Xenopus. During embryonic and larval development, x-Eomes and x-Lhx5 were expressed in highly similar patterns, in the lateral and latero-ventral w...

journal_title：Neuroreport

authors： Moreno N,Bachy I,Rétaux S,González A

更新日期：2003-12-19 00:00:00

abstract：:Methylphenidate (Ritalin) is a psychostimulant drug used to treat children with attention deficit hyperactivity disorder. Despite its widespread and increasing clinical use, little is known about the long-term consequences of drug treatment. We compared the effects of a single injection of methylphenidate with that of...

journal_title：Neuroreport

authors： Chase TD,Brown RE,Carrey N,Wilkinson M

更新日期：2003-04-15 00:00:00

abstract：:We have isolated a cDNA encoding an inwardly rectifying K+ channel (HH-IRK1) from human heart. The cDNA codes for a 427-amino acid protein, with two putative transmembrane domains and an H5 region. The primary structure of HH-IRK1 is homologous to that of the IRK1 channel cloned from a mouse macrophage-like cell line....

journal_title：Neuroreport

authors： Raab-Graham KF,Radeke CM,Vandenberg CA

更新日期：1994-12-20 00:00:00

abstract：:Altered glutamate signaling is associated with Parkinson's disease. To study the involvement of the cystine/glutamate antiporter in the pathogenesis of Parkinson's disease, we developed new polyclonal antibodies recognizing xCT, the specific subunit of this antiporter. The striatal xCT protein expression level was inv...

journal_title：Neuroreport

authors： Massie A,Schallier A,Mertens B,Vermoesen K,Bannai S,Sato H,Smolders I,Michotte Y

更新日期：2008-10-29 00:00:00

abstract：:Although prenatal stress has been repeatedly shown to inhibit adult neurogenesis in the dentate gyrus of offspring, its effects on embryonic and early postnatal brain development are not well described. Here, using the cell proliferation marker 5-bromo-2'-deoxyuridine, we examine for the first time the effect of prena...

journal_title：Neuroreport

authors： Kawamura T,Chen J,Takahashi T,Ichitani Y,Nakahara D

更新日期：2006-10-02 00:00:00

abstract：:The hypothalamus is a limbic structure involved in the emergence and persistence of major depressive disorder symptoms. Previous studies have indicated that major depressive disorder patients exhibited dysregulation between the hypothalamus and cerebral regions. However, it is still unclear about the exact hypothalami...

journal_title：Neuroreport

authors： Wang D,Xue SW,Tan Z,Wang Y,Lian Z,Sun Y

更新日期：2019-11-06 00:00:00

abstract：:Neuromagnetic signals evoked by synthesized syllables (/bae/ and /gae/) were recorded over the left auditory cortex of healthy humans. The fundamental frequencies of the syllables varied as if the same speaker had pronounced them at 16 different pitches. Specific mismatch responses to infrequent syllables among freque...

journal_title：Neuroreport

authors： Aulanko R,Hari R,Lounasmaa OV,Näätänen R,Sams M

更新日期：1993-09-30 00:00:00