Abstract:
:Neuromagnetic signals evoked by synthesized syllables (/bae/ and /gae/) were recorded over the left auditory cortex of healthy humans. The fundamental frequencies of the syllables varied as if the same speaker had pronounced them at 16 different pitches. Specific mismatch responses to infrequent syllables among frequent syllables of the other type indicated that phonetically invariant information had been extracted at the level of the auditory cortex from the extensive irrelevant pitch variation. Such a detection mechanism is necessary for perceiving speech sounds in natural situations with a great deal of acoustic variation present.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Aulanko R,Hari R,Lounasmaa OV,Näätänen R,Sams Mdoi
10.1097/00001756-199309150-00018subject
Has Abstractpub_date
1993-09-30 00:00:00pages
1356-8issue
12eissn
0959-4965issn
1473-558Xjournal_volume
4pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Apolipoprotein E (apoE) and the beta-amyloid peptide are both found in the senile plaques associated with Alzheimer's disease. Several studies have recently determined that apoE can prevent beta-amyloid fibril (Abetaf) formation in vitro. In vivo, apoE is normally associated with a lipid source. We show that both reco...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199810050-00031
更新日期:1998-10-05 00:00:00
abstract::Primate vision consists mostly of periods of stable fixation separated by rapid saccadic eye movements. Each saccade brings a new scene onto the retina, and each new scene results in a burst of activity in the neurons of visual cortex. It might be expected that the activity of these neurons should only represent what ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200301200-00020
更新日期:2003-01-20 00:00:00
abstract::Upon perfusion with Mg2+-free artificial cerebrospinal fluid (ACSF) organotypic hippocampal slice cultures develop seizure-like events and tonic recurrent discharges in which areas CA3 and CA1 and, in contrast to acute slices, also the dentate gyrus (DG) participate. Using the fluorescent dye propidium iodide (PI) we ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199902050-00002
更新日期:1999-02-05 00:00:00
abstract::An exaggerated startle response caused by mutations of the alpha 1 subunit gene of the inhibitory glycine receptor (GLRA1) is the key symptom of human hyperekplexia or startle disease. The recessive mouse mutant spasmodic (spd) carries a missense mutation in the corresponding murine Glra1 gene which reduces the affini...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199602290-00030
更新日期:1996-02-29 00:00:00
abstract::The brain-derived neurotrophic factor (BDNF) affects the developing cerebellar granule cells. Exposure of 9-11-day-old primary cultures of rat cerebellar granule neurones for 3 h to a more depolarizing medium (additional 15-30 mM KCl) stimulated the release of glutamate and increased the BDNF mRNAs levels. This BDNF a...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1993-09-03 00:00:00
abstract::Evoked magnetic fields over the entire head were measured during a semantic judgment task, in which conditions of the pre-test learning session were manipulated. Subjects learnt related and unrelated category-noun pairs, and were then asked to judge the relationship between category and noun. Unrelated pairs evoked ac...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200102120-00005
更新日期:2001-02-12 00:00:00
abstract::Other-race faces are less accurately recognized than same race faces but classified faster by race. Using event-related potentials (ERPs), we captured the brain temporal dynamics of face classification by race processing performed by 12 Caucasian participants. As expected, participants were faster to classify by race ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200404090-00034
更新日期:2004-04-09 00:00:00
abstract::Previously we found that musicians have significantly larger anterior corpus callosum (CC). In the current study, we intended to replicate and extend our previous results using a new and larger sample of gender-matched subjects (56 right-handed professional musicians and 56 age- and handedness-matched controls). We fo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200302100-00009
更新日期:2003-02-10 00:00:00
abstract::The dynamics of intracellular calcium concentration ([Ca2+]i) following activation of low voltage-activated (LVA) and high voltage-activated (HVA) Ca2+ currents were studied in identified relay neurons and interneurons of the rat dorsal lateral geniculate nucleus (LGNd) in situ using Ca2+ imaging and patch-clamp techn...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199707280-00001
更新日期:1997-07-28 00:00:00
abstract::Experience affects how brains respond to sound. Here, we examined how the sensitivity and selectivity of auditory cortical neuronal responses were affected in adult rats by the repeated presentation of a complex sound that was paired with basal forebrain stimulation. The auditory cortical region that was responsive to...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200107200-00047
更新日期:2001-07-20 00:00:00
abstract::In an earlier screening, we identified several genes for kinases that might control the extension of neurites. One of these genes encoded a leukocyte tyrosine kinase (LTK), which is a receptor tyrosine kinase whose ligands remain to be identified. To examine the possible role of this LTK in neurite outgrowth, we const...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283186bf8
更新日期:2008-11-19 00:00:00
abstract::Cells overexpressing the beta-amyloid precursor protein possessing a mutation found in familial Alzheimer's disease overproduce beta-amyloid peptide (A beta). Because these findings were based on immunological identification, we have chemically characterized the peptides produced. Purified A beta fragments from the co...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199308000-00011
更新日期:1993-08-01 00:00:00
abstract::Age-related depletion of androgens in men results in functional impairments in androgen-responsive tissues, such as the brain, resulting in increased risk for Alzheimer's disease. To investigate the relationship between normal age-related hormone loss and Alzheimer's disease risk, we evaluated the brain and serum leve...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328331f968
更新日期:2009-11-25 00:00:00
abstract::Using reverse transcription-polymerase chain reaction and in situ hybridization, we investigated the expression and cellular localization of ciliary neurotrophic factor receptor alpha (CNTFRalpha) in the rat retina following optic nerve transection (ONT). Following ONT, a signal for CNTFRalpha mRNA appeared in a layer...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200011270-00057
更新日期:2000-11-27 00:00:00
abstract::Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD) yet inconsistencies in activation have been reported. One source of variance are individual differences in 5-HTTLPR genotype where the short (S), relative to long (L) allele, corresponds with greater amygdala activation. Howe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000210
更新日期:2014-08-20 00:00:00
abstract::Subpopulations of olfactory receptor neurons, which are dispersed throughout the olfactory neuroepithelium, express specific cell surface carbohydrates and project to discrete regions of the olfactory bulb. Cell surface carbohydrates such as N-acetyl-lactosamine have been postulated to mediate sorting and selective fa...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199710200-00001
更新日期:1997-10-20 00:00:00
abstract::The role of dopaminergic pathways in the retina in controlling the functional state of the pineal was investigated. Dopaminergic agents were injected into the eyes of dark-adapted chickens which were maintained in the dark. Changes in the activity of N-acetyltransferase (NAT) in the retina and pineal were then monitor...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199502000-00010
更新日期:1995-02-15 00:00:00
abstract::Five patients with left visual neglect after right hemisphere lesions were examined with a line bisection and a reading task under five different conditions: head and trunk straight ahead, head or trunk oriented 20 degrees to the left and head or trunk oriented 20 degrees to the right. Fixation was always straight ahe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199708180-00009
更新日期:1997-08-18 00:00:00
abstract::TECTA and DFNA5 are the mouse orthologues of the human deafness-associated genes TECTA and DFNA5. To determine how expression of these genes is regulated during development, relative mRNA abundance was examined in mice by non-radioactive RT-PCR. TECTA mRNA was detected on embryonic day 15 (E15), increased to its highe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200110290-00016
更新日期:2001-10-29 00:00:00
abstract::We present the first assessment of motion vision in childhood autism. Postural reactivity to visually perceived motion was measured in five autistic children and 12 normal controls of the same chronological age. Anteroposterior as well as total body sway occurring on a force platform in response to movements in the vi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199505300-00034
更新日期:1995-05-30 00:00:00
abstract::Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disease mediated by IgG1 or IgG3 antibodies to the GluN1 subunit of the NMDAR, resulting in downregulation of NMDARs. Early diagnosis, prompt reduction of anti-NMDAR antibodies, and removal of associated ovarian tumors when identified are importa...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000851
更新日期:2017-09-27 00:00:00
abstract::A synchronizing volley of excitation was delivered to cells from the primary visual cortex of the anaesthetized cat by an electrical pulse stimulation of the optic radiations. In intracellular records, this resulted in an initial, fast depolarization of the membrane potential followed by a longer lasting (266 ms) hype...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200004270-00020
更新日期:2000-04-27 00:00:00
abstract::α-Gustducin (Gα-gust) is the α subunit of the heterotrimeric G-protein complex specific for taste receptor cells of the tongue. However, it has been shown to be present in ectopic regions, such as airways and digestive tract. Recently, Gα-gust was found within neurons in various regions of the mouse brain. In this stu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328343701f
更新日期:2011-02-16 00:00:00
abstract::To observe sequential stages in tactile pattern discrimination and their modification with and without attention, we used whole-head anatomically constrained magnetoencephalography to spatiotemporally map brain responses. Eight, normal, right-handed participants discriminated between two patterns presented on the palm...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32832c5f65
更新日期:2009-07-01 00:00:00
abstract::Mesencephalic astrocyte-derived neurotrophic factor (MANF) - one of a new class of astrocyte-derived human proteins--selectively promotes the survival of dopamine neurons of the ventral midbrain. Using the whole-cell clamp technique, we looked for acute effects of MANF on gamma-aminobutyric acid type A (GABAA) recepto...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000201504.23255.bc
更新日期:2006-02-27 00:00:00
abstract::To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283642a93
更新日期:2013-09-11 00:00:00
abstract::Regional cerebral blood flow (rCBF) was measured using PET and H2(15)O in Parkinson's disease (PD) patients with predominantly right-sided akinetic-rigid symptoms and in control subjects during the execution of an externally cued motor task either with the left or the right hand. During the execution of the task with ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200003200-00026
更新日期:2000-03-20 00:00:00
abstract::Voltage-gated sodium channels consist of a pore-containing alpha-subunit and one or more auxiliary beta-subunits, which may modulate channel function. We previously demonstrated that sodium channel SNS/PN3 alpha-subunits were decreased in human sensory cell bodies after spinal root avulsion injury, and accumulated at ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200103050-00012
更新日期:2001-03-05 00:00:00
abstract::Event-related potential (ERP) studies have shown that responses to illusory (IC), as compared to no contours (NC), may differ within 200 ms following stimulus presentation. However, whether these responses reflect the modulation of similar, or the activation of distinct brain regions has never been assessed. Using ERP...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200205240-00013
更新日期:2002-05-24 00:00:00
abstract::Multiple signal classification is an alternative to the traditional dipole fitting source analysis methods. Our aim was to assess the clinical usefulness of this algorithm and to compare the localization of the epileptiform electroencephalography discharges with the regions of altered cerebral blood flow in 10 patient...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000230517.93714.f6
更新日期:2006-08-21 00:00:00