Daily methylphenidate administration attenuates c-fos expression in the striatum of prepubertal rats.

abstract：:Axonal atrophy may reflect earlier and more reversible events in neurodegeneration and ageing than somatic atrophy. Innervation density by sympathetic fibres from the rat superior cervical ganglion (SCG) to the middle cerebral artery (MCA) decreases dramatically in old age, while that to the iris is largely unchanged....

journal_title：Neuroreport

authors： Kuchel GA,Poon T,Irshad K,Richard C,Julien JP,Cowen T

更新日期：1997-02-10 00:00:00

abstract：:Nogo receptor 1 (NgR1) is the most important Nogo-A receptor. By its interaction with myelin-associated inhibitory proteins, NgR1 inhibits the regeneration of axons and is extensively expressed in the central nervous system. However, the expression of NgR1 in regenerable neurons, such as olfactory neurons, and its exp...

journal_title：Neuroreport

authors： Chen HX,Zeng XP,Sun YQ,Fu QL

更新日期：2016-07-06 00:00:00

abstract：:We compared beta-amyloid peptide (Abeta) levels in the serum, CSF and brain (hippocampus) and correlated these with spatial learning in APP+PS1 transgenic mice. Compared with non-transgenic littermates, male 14-month-old APP + PS1 mice were impaired in spatial learning in the water maze. Among the APP + PS1 mice, only...

journal_title：Neuroreport

authors： Liu L,Tapiola T,Herukka SK,Heikkilä M,Tanila H

更新日期：2003-01-20 00:00:00

abstract：:We investigated the mRNA levels of neuronal, inducible, endothelial nitric oxide synthases (nNOS, iNOS, eNOS) and tumor necrosis factor-alpha (TNF-alpha) in a rat dorsal root ganglion (DRG) after tourniquet application to a hind limb to identify molecules that trigger secondary events after peripheral nerve injury. Si...

journal_title：Neuroreport

authors： Abe S,Mizusawa I,Kanno K,Yabashi A,Suto M,Kuraya M,Honda T,Hiraiwa K

更新日期：2003-12-02 00:00:00

abstract：:Adenovirus vectors containing a marker gene (lacZ from Escherichia coli) are potent for transferring the gene to neurones after intraparenchymal injections. Expression of the marker gene may lead to the synthesis of an enormous amount of beta-galactosidase which diffuses throughout the entire neurone, providing a 'Gol...

journal_title：Neuroreport

authors： Lisovoski F,Cadusseau J,Akli S,Caillaud C,Vigne E,Poenaru L,Stratford-Perricaudet L,Pericaudet M,Kahn A,Peschanski M

更新日期：1994-05-09 00:00:00

abstract：:The neurotrophin-inducible gene VGF plays an important role in the maintenance of organismal energy balance and in the mediation of hippocampal synaptic activity. The regulatory mechanism of VGF transcription is not fully understood. The neuron-restrictive silencer factor (NRSF) binds with the neuron-restrictive silen...

journal_title：Neuroreport

authors： Moon SM,Kim JS,Park BR,Kim DK,Kim SG,Kim HJ,Chun HS,Lee BK,Kim CS

更新日期：2015-02-11 00:00:00

abstract：:The conditioned place preference (CPP) induced by cocaine 2.5 mg/kg was measured in rats pre-exposed to ethanol (14 days with only 10% v/v ethanol followed by a free choice between ethanol solution and water for 14 days). Rats were divided according to their alcohol intake during the free choice period into low-drinki...

journal_title：Neuroreport

authors： Le Pen G,Duterte-Boucher D,Daoust M,Costentin J

更新日期：1998-08-24 00:00:00

abstract：:HEL 92.1.7 cells were immobilized among nerve growth factor (NGF)-differentiated PC12 cells. Nicotine caused an immediate Ca2+ mobilisation in the PC12 cells followed by a delayed secondary Ca2+ response in the HEL 92.1.7 cells. The Ca2+ elevation in response to nicotine in PC12 cells was abolished by Na+ removal. The...

journal_title：Neuroreport

authors： Krjukova J,Akerman KE

更新日期：2002-07-02 00:00:00

abstract：:We investigated the mode of action of argiotoxin636 on isolated N-methyl-D-aspartate (NMDA) receptor channels in cultured cerebellar granule cells. We found that the toxin blocks NMDA channels by decreasing their opening probability and by inducing a flickering activity, in a voltage-dependent manner. Our results indi...

journal_title：Neuroreport

authors： Fagni L,Bockaert J

更新日期：1995-05-09 00:00:00

abstract：:To achieve neuronal differentiation of mouse bone mesenchymal stem cells (bMSCs) into neuron-like cells and explore the role of miR-122-5p that may regulate T-box brain 1 (Tbr1) expression during the induction. BMSCs were cultured and induced with butylated hydroxyanisole, retinoic acid (RA), basic fibroblast growth f...

journal_title：Neuroreport

authors： Yang Y,Shen Z,Sun W,Gao S,Li Y,Guo Y

更新日期：2017-05-03 00:00:00

abstract：:The effect of temporal interference of physiological signals on time-lag effective connectivity, derived from a functional network connectivity tool box (FNC), was examined by a blood-oxygen-level-dependent functional MRI study of action. The known effect of physiological signals on time-lag FNC was verified by (a) co...

journal_title：Neuroreport

authors： Huang JM,Cheng CM,Chou CC,Chen YC,Hsu PY,Yeh TC

更新日期：2013-01-09 00:00:00

abstract：:We conducted semiautomated, atlas-based analyses of regional brain volume changes on MRIs of children and adolescents with Down syndrome (DS) (N=15), DS with comorbid autism spectrum disorder (ASD) (N=15), and age-matched or sex-matched typically developing controls (N=22). Selective volumetric changes were correlated...

journal_title：Neuroreport

authors： Carter JC,Capone GT,Kaufmann WE

更新日期：2008-04-16 00:00:00

abstract：:In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....

journal_title：Neuroreport

authors： Le Van Quyen M,Martinerie J,Baulac M,Varela F

更新日期：1999-07-13 00:00:00

abstract：:Densities of serotonin transporters (5-HTT) in the postmortem neocortex of behaviorally assessed Alzheimer's disease (AD) patients and aged controls were measured by radioligand binding with [3H]citalopram. It was found that 5-HTT sites in the temporal cortex of AD patients with prominent antemortem anxiety were unalt...

journal_title：Neuroreport

authors： Tsang SW,Lai MK,Francis PT,Wong PT,Spence I,Esiri MM,Keene J,Hope T,Chen CP

更新日期：2003-07-18 00:00:00

abstract：:Changes in nitric oxide (NO) concentration and cerebral blood flow (CBF) in the parietal cortex during hypercapnoea were investigated in anaesthetized rats, using a NO-selective electrode and laser Doppler flowmetry. When hypercapnoea was induced by inhalation of 5% CO2 for 10 min, both the NO concentration and CBF in...

journal_title：Neuroreport

authors： Harada M,Fuse A,Tanaka Y

更新日期：1997-03-03 00:00:00

abstract：:Neurofibromin, the product of the neurofibromatosis 1 (NF1) gene, is an important tumor suppressor protein expressed most abundantly in the nervous system. Within the central nervous system, neurofibromin has been localized to neurons and oligodendrocytes but not astrocytes. As individuals with NF1 are at an increased...

journal_title：Neuroreport

authors： Hewett SJ,Choi DW,Gutmann DH

更新日期：1995-07-31 00:00:00

abstract：:Using quantitative autoradiography, the present study examined ionotropic glutamatergic receptor binding sites using [3H]dizocilpine, [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate, and [3H]kainate in the posterior cingulate cortex of schizophrenia patients and matched controls. We found a significant increa...

journal_title：Neuroreport

authors： Newell KA,Zavitsanou K,Huang XF

更新日期：2005-08-22 00:00:00

abstract：:The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of all...

journal_title：Neuroreport

authors： Collier DA,Arranz MJ,Sham P,Battersby S,Vallada H,Gill P,Aitchison KJ,Sodhi M,Li T,Roberts GW,Smith B,Morton J,Murray RM,Smith D,Kirov G

更新日期：1996-07-08 00:00:00

abstract：:Inherited retinal degenerations such as retinitis pigmentosa (RP) are characterized by progressive loss of photoreceptors, apparently by apoptosis, and our recent report of increased secreted Frizzled-related protein-2 (SFRP2) in RP retinas suggests altered Wnt signalling may be a component of the degenerative process...

journal_title：Neuroreport

authors： Jones SE,Jomary C,Grist J,Stewart HJ,Neal MJ

更新日期：2000-12-18 00:00:00

abstract：:The role of the medial septum in suppressing paradoxical sleep and promoting slow wave sleep was suggested on the basis of neurotoxic lesion studies. However, these conclusions need to be substantiated with further experiments, including chemical stimulation studies. In this report, the medial septum was stimulated in...

journal_title：Neuroreport

authors： Mukherjee D,Kaushik MK,Jaryal AK,Kumar VM,Mallick HN

更新日期：2012-05-09 00:00:00

abstract：:We examined covert and overt orienting in response to non-predictive gaze direction cues and investigated whether the subcortical superior colliculus (SC) plays a role in this type of orienting. Participants viewed a centrally presented gazing schematic face and responded to targets appearing at gazed-at or non-gazed-...

journal_title：Neuroreport

authors： Friesen CK,Kingstone A

更新日期：2003-03-03 00:00:00

abstract：:In the adult rat hippocampal formation, neurogenesis occurs in the dentate gyrus subgranular zone (SGZ). We used laser capture microdissection and an antidepressant-related genes microarray to analyze gene expression profiles of cells from the SGZ and from the outermost granule cell layer. Of the differentially expres...

journal_title：Neuroreport

authors： Yamada M,Takahashi K,Ukai W,Hashimoto E,Saito T,Yamada M

更新日期：2010-01-27 00:00:00

abstract：:A number of epidemiological studies suggest that estrogen therapy is linked to a reduced risk of developing Alzheimer's disease (AD). The present study was conducted to evaluate the effect of 17beta-estradiol on beta-amyloid (Abeta)-induced toxicity and was performed in rat pheochromocytoma PC 12 cells by measuring th...

journal_title：Neuroreport

authors： Svensson AL,Nordberg A

更新日期：1999-11-26 00:00:00

abstract：:Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural...

journal_title：Neuroreport

authors： Kéri S,Gulyás B

更新日期：2003-06-11 00:00:00

abstract：:Although the role of Bcl-2-related proteins as regulators of the apoptotic process has been well documented, recent studies suggest that they might also be implicated in neuronal differentiation. We have studied by immunocytochemistry, Western blotting and RT-PCR the expression pattern of Bcl-xL, Bcl-2 and BAX in the ...

journal_title：Neuroreport

authors： Guillemain I,Gaboyard S,Fontès G,Saunier M,Privat A,Patey G

更新日期：2000-05-15 00:00:00

abstract：:The tonic discharge of rat medial vestibular nucleus (MVN) neurons, and their responsiveness to GABA receptor agonists were investigated in slices prepared from aged rats (24 months old). Aged MVN neurons showed regular spontaneous activity similar to that seen in slices from young adults. However the inhibitory effec...

journal_title：Neuroreport

authors： Him A,Johnston AR,Yau JL,Seckl J,Dutia MB

更新日期：2001-12-21 00:00:00

abstract：:Voltage-gated sodium channels (VGSCs) are concentrated in the postsynaptic membrane at the adult rat neuromuscular junction (NMJ). We have used immunolabelling to determine the pattern of initial VGSC accumulation during development. At birth, but not 3 days before, VGSC labelling is detectable at the NMJ and in the p...

journal_title：Neuroreport

authors： Wood SJ,Shewry K,Young C,Slater CR

更新日期：1998-06-22 00:00:00

abstract：:This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...

journal_title：Neuroreport

authors： Yan H,Zhang HY,Tang XC

更新日期：2007-05-07 00:00:00

abstract：:The alpha 2-macroglobulin receptor/low-density lipoprotein receptor-related protein (alpha 2-M-R/LRP) is a multifunctional receptor which has been implicated in lipoprotein metabolism, clearance of proteinase-proteinase inhibitor complexes and regulation of growth factor/cytokine metabolism. This receptor is abundantl...

journal_title：Neuroreport

authors： Birkenmeier G,Grosche J,Reichenbach A

更新日期：1996-12-20 00:00:00

abstract：:Hindlimb unloading (HU) can cause motion and cognition dysfunction, although its cellular and molecular mechanisms are not well understood. The aim of the present study was to determine the stereological parameters of the brain areas involved in motion (motor cortex) and spatial learning - memory (hippocampus) under a...

journal_title：Neuroreport

authors： Salehi MS,Mirzaii-Dizgah I,Vasaghi-Gharamaleki B,Zamiri MJ

更新日期：2016-11-09 00:00:00