Pre-exposure to alcohol does not sensitize to the rewarding effects of cocaine.

abstract：:The present study explored duration mismatch negativity (MMN) reduction in schizophrenia. Duration MMN studies usually employ tones of very short duration (< 200 ms). For stimuli < 200 ms in duration, an increment in duration is accompanied by an increase in perceived loudness. It was previously proposed that the effe...

journal_title：Neuroreport

authors： Todd J,Michie PT,Jablensky AV

更新日期：2001-12-21 00:00:00

abstract：:Insulin-like growth factor (IGF)-I is essential for cerebellar granule neuron survival and a decline in IGF-I is implicated in various age-dependent processes. Here we show that IGF-I mRNA levels are decreased in the cerebellum of old rats compared with young rats and this was associated with increased cell death and ...

journal_title：Neuroreport

authors： Pañeda C,Arroba AI,Frago LM,Holm AM,Rømer J,Argente J,Chowen JA

更新日期：2003-08-26 00:00:00

abstract：:Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...

journal_title：Neuroreport

authors： Kempster S,Collins ME,Edington N

更新日期：2004-10-05 00:00:00

abstract：:Using functional magnetic resonance imaging during word generation and spatial judgement (Landmark task), we investigated how hemispheric specializations for language and spatial processing interact in healthy individuals. We found individuals with atypical, right-hemispheric dominance for language to have more bilate...

journal_title：Neuroreport

authors： Jansen A,Flöel A,Menke R,Kanowski M,Knecht S

更新日期：2005-06-21 00:00:00

abstract：:Previous studies have shown that spatial memory retention is affected by the metabotropic glutamate receptor (mGluR) influencing agents (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) and trans-azetidine-2,4-dicarboxylic acid (tADA). In the present investigation we examined whether the mGluR antagonist MCPG (20 mM an...

journal_title：Neuroreport

authors： Wetzel W,Wagner T,Reymann KG,Riedel G

更新日期：1995-11-27 00:00:00

abstract：:Although accumulating evidence suggests that there are significant anatomical and histological differences between the sulci and gyri of the cerebral cortex, whether there is a difference in the distribution of interneurons between the two cortical regions remains largely unknown. In this study, we systematically comp...

journal_title：Neuroreport

authors： Gao JT,Liu Y,Gong D,Feng XM,Wan P,Luo XF,Zhu WH,Hou JC,Lv SJ

更新日期：2019-10-16 00:00:00

abstract：:Alzheimer disease (AD) patients show increased plasma levels of homocysteine, whose conversion to methionine is catalyzed by methionine synthase (MS). Although altered MS activity may result from the MS A2756G polymorphism, the latter's possible associ-ation with AD remains unexplored. To assess whether the MS A2756G ...

journal_title：Neuroreport

authors： Beyer K,Lao JI,Latorre P,Riutort N,Matute B,Fernández-Figueras MT,Mate JL,Ariza A

更新日期：2003-07-18 00:00:00

abstract：:To detect stress responses of the brain to subarachnoid hemorrhage (SAH), we investigated the expression of immediate early genes (IEGs) and hsp70 mRNA by in situ hybridization. Experimental SAH was produced in 49 rats by endovascular penetration. We also monitored the intracranial pressure (ICP) changes. The genes c-...

journal_title：Neuroreport

authors： Harada S,Kamiya K,Masago A,Iwata A,Yamada K

更新日期：1997-10-20 00:00:00

abstract：:To investigate the effect of the N-terminal Slit2 protein on neuronal survival and development, recombinant human N-terminal Slit2 (N-Slit2) was assayed against isolated embryonic chick dorsal root ganglion sensory, ciliary ganglion and paravertebral sympathetic neurons. N-Slit2 promoted significant levels of neuronal...

journal_title：Neuroreport

authors： Piper M,Nurcombe V,Reid K,Bartlett P,Little M

更新日期：2002-12-03 00:00:00

abstract：:Prism adaptation reduces some symptoms of neglect; however the mechanisms underlying such changes are poorly understood. We suggest that prisms influence neglect by acting on dorsal stream circuits subserving visuomotor control, with little influence on perceptual aspects of neglect. We examined prism adaptation in th...

journal_title：Neuroreport

authors： Striemer CL,Danckert J

更新日期：2010-04-21 00:00:00

abstract：:Levels of mRNAs encoding for the two isoforms of glutamate decarboxylase, GAD67 and GAD65, were quantified in the rat striatum and cerebral cortex following single injections of the non-competitive NMDA receptor antagonist MK-801. Acute MK-801 induced a dose-dependent decrease in GAD65 mRNA levels in ventral sectors o...

journal_title：Neuroreport

authors： Laprade N,Soghomonian JJ

更新日期：1995-10-02 00:00:00

abstract：:Surface texture can be perceived not only from tactile, but also from auditory and visual sensory cues. In our previous psychophysical study, we demonstrated that humans can recognize surface stickiness using only one kind of sensory modality without any difficulty. However, the brain regions that would be activated b...

journal_title：Neuroreport

authors： So Y,Kim SP,Kim J

更新日期：2020-03-25 00:00:00

abstract：:Papaverine is a non-specific vasodilatory drug, which was found to unexpectedly cause opening of the blood-brain barrier (BBB). We studied the expression of two endothelial cell related markers, endothelial barrier antigen (EBA) as a marker of BBB intactness, and matrix metalloproteinase-9 (MMP-9), an extracellular ma...

journal_title：Neuroreport

authors： Bhattacharjee AK,Kondoh T,Ikeda M,Kohmura E

更新日期：2002-12-03 00:00:00

abstract：:We investigated whether in vivo excitotoxicity was mediated by a mechanism of programmed cell death called apoptosis. Neurotoxic doses of kainic acid (1.2 nmol) and quinolinic acid (120 nmol) were unilaterally injected in the dorsal hippocampus of anesthetized rats. Eight or 16 h later the animals were killed and DNA ...

journal_title：Neuroreport

authors： Ignatowicz E,Vezzani AM,Rizzi M,D'Incalci M

更新日期：1991-11-01 00:00:00

abstract：:The efficacy and safety of thrombolysis with different dose regimens of recombinant tissue plasminogen activator (rt-PA) and its combination with aspirin was tested in an embolic stroke model. In rats the carotid territory was embolized with a single clot formed in a polyethylene tube and washed with saline. Fifteen m...

journal_title：Neuroreport

authors： Overgaard K,Sereghy T,Pedersen H,Boysen G

更新日期：1992-10-01 00:00:00

abstract：:Chronic ethanol exposure is known to alter the polyphosphoinositide (poly-PI) signaling pathway, although the exact sight of regulation is not well understood. In this study, C57B1/6J mice were given a control or an ethanol (6 g kg-1 body wt) liquid diet by gastric intubation daily for 4 weeks. Examination of levels o...

journal_title：Neuroreport

authors： Simonyi A,Zhang JP,Sun AY,Sun GY

更新日期：1996-09-02 00:00:00

abstract：:Hydroxyindole-O-methyltransferase (HIOMT), is the last enzyme of the melatonin biosynthesis pathway. We have applied immunocytochemistry and in situ hybridization to localize HIOMT producing cells, in the chicken epithalamus including the pineal gland. The selectivity of the hybridization signal over melatoninergic ce...

journal_title：Neuroreport

authors： Grève P,Bernard M,Voisin P,Cogné M,Collin JP,Guerlotte J

更新日期：1993-06-01 00:00:00

abstract：:The aim of this study was to investigate whether frontal lobe damage affects thalamic volume in humans. Ipsilateral and contralateral thalamic areas were measured in 0.5T T1-weighted sagittal magnetic resonance images in 12 patients, first at the time of their surgery for relief of a unilateral frontal lobe brain tumo...

journal_title：Neuroreport

authors： Hulshoff Pol HE,van der Flier WM,Schnack HG,Tulleken CA,Ramos LM,van Ree JM,Kahn RS

更新日期：2000-09-11 00:00:00

abstract：:A combined microdialysis/microinfusion technique was used to investigate whether arginine vasopressin (AVP) is involved in the regulation of its own release into the extracellular fluid of the supraoptic nucleus in vivo. While intranuclear neuropeptide release was monitored, 0.33 microliter of either vehicle, lysine v...

journal_title：Neuroreport

authors： Wotjak CT,Ludwig M,Landgraf R

更新日期：1994-06-02 00:00:00

abstract：:A previous investigation has suggested that the hyperpolarization-activated cation current Ih does not contribute to the spontaneous firing of midbrain dopaminergic neurons. This conclusion was reached using Cs(-1). We have re-examined this question with extracellular recordings in slices using the more specific block...

journal_title：Neuroreport

authors： Seutin V,Massotte L,Renette MF,Dresse A

更新日期：2001-02-12 00:00:00

abstract：:Regulation of CNTF mRNA was investigated in primary cortical astrocytes cultured from newborn rats and in C6 glioma cells. Northern blot analysis indicated that semi-confluent astrocyte cell cultures. CNTF added to confluent astrocyte cultures down-regulated CNTF message in a dose-dependent fashion. In contrast, when ...

journal_title：Neuroreport

authors： Meyer V,Unsicker K

更新日期：1994-10-03 00:00:00

abstract：:This study investigated whether neural mechanisms of self-face recognition are modulated by attention by recording event-related brain potentials associated with self-face recognition. Participants identified head orientations of self-faces and familiar or unfamiliar other faces presented briefly at the center of the ...

journal_title：Neuroreport

authors： Sui J,Zhu Y,Han S

更新日期：2006-03-20 00:00:00

abstract：:The amounts of three adenylyl cyclase (AC) subtypes in membranes from brain obtained post-mortem from patients with dementia of Alzheimer type (DAT) and controls were studied by Western blotting using polyclonal antibodies. AC subtypes were characterized by preabsorption by complementary peptides, species difference, ...

journal_title：Neuroreport

authors： Yamamoto M,Ozawa H,Saito T,Frölich L,Riederer P,Takahata N

更新日期：1996-11-25 00:00:00

abstract：:In this study, we examine through electrophysiological measures three alternative mechanisms underlying musical chord priming: psychoacoustic distance, common parent-key, and distance along the circle of fifths. In contrast with previous behavioral studies, we present complex tones which do not blur the melodic compon...

journal_title：Neuroreport

authors： Granot RY,Hai A

更新日期：2009-06-17 00:00:00

abstract：:Glutamatergic excitotoxicity has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). However, activation of metabotropic glutamate receptors (mGluRs) is neuroprotective in several paradigms. We therefore tested the effect of selective mGluR agonists on cultured chick embryonic motor neurons. Ac...

journal_title：Neuroreport

authors： Anneser JM,Horstmann S,Weydt P,Borasio GD

更新日期：1998-06-22 00:00:00

abstract：:Oscillatory activity is a ubiquitous property of brain signals, and yet relatively few studies have investigated how the phase of such ongoing oscillations affects our cognition. One of the main findings in this field is that the phase of electroencephalography (EEG) in the alpha band can affect perception of millisec...

journal_title：Neuroreport

authors： Jalali A,Tata MS,Gruber AJ,Luczak A

更新日期：2019-04-10 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a technique for noninvasively stimulating specific cortical regions of the brain with small (<2 mA) and constant direct current on the scalp. tDCS has been widely applied, not only for medical treatment, but also for cognitive and somatosensory function enhancement, mo...

journal_title：Neuroreport

authors： Song M,Shin Y,Yun K

更新日期：2014-12-17 00:00:00

abstract：:Diabetes is often associated with impairments in brain functioning. However, the injury of specific functioning areas of the brain is not clear. To address this problem, the present study was designed to investigate possible brain functioning change in specific brain areas, particularly in areas associated with vision...

journal_title：Neuroreport

authors： Wang Z,Lu Z,Li J,Pan C,Jia Z,Chen H,Ge X

更新日期：2017-01-18 00:00:00

abstract：:To clarify possible interaction between the ventral hippocampal cannabinoid CB2 receptors and the cholinergic system in control of the memory process, the effects of cannabinoid and acetylcholine receptor agents on memory consolidation have been investigated in mice. Animals implanted with bilateral cannulas at the CA...

journal_title：Neuroreport

authors： Nasehi M,Forouzanmehr E,Khakpai F,Zarrindast MR

更新日期：2020-01-27 00:00:00

abstract：:Human morning/evening preferences has recently been reported to be associated with polymorphism of the 3' flanking region of the Clock gene, which was the first identified mammalian circadian clock gene. We recorded body temperature, spontaneous activity, electroencephalogram and electromyogram for 48 h in mice with J...

journal_title：Neuroreport

authors： Sei H,Oishi K,Morita Y,Ishida N

更新日期：2001-05-25 00:00:00