Chronic ethanol on mRNA levels of IP3R1, IP3 3-kinase and mGluR1 in mouse Purkinje neurons.

abstract：:We screened proteins for interaction with presenilin (PS) 1, and cloned the full-length cDNA of human delta-catenin, which encoded 1225 amino acids. Yeast two-hybrid assay, GST binding assay and immunoprecipitation demonstrated that delta-catenin interacted with a hydrophilic loop region in the endoproteolytic C-termi...

journal_title：Neuroreport

authors： Tanahashi H,Tabira T

更新日期：1999-02-25 00:00:00

abstract：:Antisera were produced against synthetic peptides predicted from the recent cloning of a delta opioid receptor, DOR-1. Confocal microscopic examination of immunostained spinal cord sections revealed that DOR-1 immunoreactive (-ir) nerve fibers and terminals form a moderately dense plexus within the superficial dorsal ...

journal_title：Neuroreport

authors： Dado RJ,Law PY,Loh HH,Elde R

更新日期：1993-12-13 00:00:00

abstract：:Little is known regarding opioid receptors in the human cerebellum. The present [11C]diprenorphine PET study investigated opioid receptor binding in the human cerebellum in vivo, and showed a differential binding level in cerebellar cortex, vermis and dentate nuclei. The additional study in vitro of opioid receptors i...

journal_title：Neuroreport

authors： Schadrack J,Willoch F,Platzer S,Bartenstein P,Mahal B,Dworzak D,Wester HJ,Zieglgänsberger W,Tölle TR

更新日期：1999-02-25 00:00:00

abstract：:We investigated the influence of gravity on the maturation of electrical properties of lumbar motoneurons and the development of their inputs from ventral descending pathways, which are important for the control of posture and locomotion. Using electrophysiological approaches in the in vitro brain stem-spinal cord pre...

journal_title：Neuroreport

authors： Brocard F,Clarac F,Vinay L

更新日期：2003-09-15 00:00:00

abstract：:Acute injury to central nervous system (CNS) triggers neurodegenerative processes that can result in serious damage or complete loss of function. After injury, production of transforming growth factor β1 (TGFβ1) increases and initiates creation of a fibrotic scar that prevents normal growth, plasticity, and recovery o...

journal_title：Neuroreport

authors： Jaskova K,Pavlovicova M,Cagalinec M,Lacinova L,Jurkovicova D

更新日期：2014-03-26 00:00:00

abstract：:In an attempt to determine whether small focal malformations of the neocortex can be visualized in vivo, focal microgyria were induced in the neocortex of otherwise normal rats by freezing injury to the developing cortical plate, and in adulthood the malformation was visualized using MRI. Induced microgyria of varying...

journal_title：Neuroreport

authors： Rosen GD,Burstein D

更新日期：1997-12-22 00:00:00

abstract：:Successful practice of clinical deep brain stimulation (DBS) calls for basic research on the mechanisms and explorations of new indications in animals. In the article, a new implantable, single-channel, low-power miniature device is proposed, which may transmit pulses chronically into the brain nucleus of freely movin...

journal_title：Neuroreport

authors： Liu H,Wang C,Zhang F,Jia H

更新日期：2017-02-08 00:00:00

abstract：:In this study, an algorithm is introduced for the automatic detection and simultaneous topographic classification of interictal regional spike activity in pediatric surface EEG records. The algorithm is based on the classification of the topographic distribution of instantaneous power by means of a 'group' trained cla...

journal_title：Neuroreport

authors： Feucht M,Hoffmann K,Steinberger K,Witte H,Benninger F,Arnold M,Doering A

更新日期：1997-07-07 00:00:00

abstract：:It is unclear whether the neural algorithm that underlies stereoscopic vision in birds incorporates both low level (camouflage breaking) and high level (depth ordering) comparisons of information available to each of the eyes. Both visual functions were successfully tested by examining transitive inference performance...

journal_title：Neuroreport

authors： van der Willigen RF,Frost BJ,Wagner H

更新日期：1998-04-20 00:00:00

abstract：OBJECTIVES:There are subclinical neurologic deficits in cirrhotic patients without overt hepatic encephalopathy. We aimed to use F-fluorodeoxyglucose PET/computed tomography to explore the impaired brain glucose metabolism of subclinical hepatic encephalopathy in cirrhosis. METHODS:Thirty-seven patients with hepatitis...

journal_title：Neuroreport

authors： Zhang W,Ning N,Li X,Li M,Duan X,Guo Y,Dang Y,Li Y,Gao J,Ye J,Yang J

更新日期：2019-08-07 00:00:00

abstract：:To determine whether EEG synchronization in sleep has a metabolic equivalent, we investigated state-dependent changes in extracellular concentrations of amino acids. In vivo microdialysis studies were performed in the ventroposterolateral (VPL) nuclei of the thalamus of cats during natural slow wave sleep (SWS), wakin...

journal_title：Neuroreport

authors： Kékesi KA,Dobolyi A,Salfay O,Nyitrai G,Juhász G

更新日期：1997-03-24 00:00:00

abstract：:Plasminogen activator inhibitor-1 is a serpin that regulates the activities of plasminogen activators. However, its physiological roles in the CNS are incompletely understood. We have found that plasminogen activator inhibitor-1 has a novel biological function in the CNS: the contribution to survival of neurites on ne...

journal_title：Neuroreport

authors： Soeda S,Imatoh T,Ochiai T,Koyanagi S,Shimeno H

更新日期：2004-04-09 00:00:00

abstract：:Behavioral and neuropsychological studies suggest that upright and inverted face stimuli are processed by computationally and anatomically distinct systems. Specifically, inverted faces seem to be addressed by general object perception systems, avoiding face-specific processes. We tested this model by examining the fM...

journal_title：Neuroreport

authors： Aguirre GK,Singh R,D'Esposito M

更新日期：1999-01-18 00:00:00

abstract：:HEL 92.1.7 cells were immobilized among nerve growth factor (NGF)-differentiated PC12 cells. Nicotine caused an immediate Ca2+ mobilisation in the PC12 cells followed by a delayed secondary Ca2+ response in the HEL 92.1.7 cells. The Ca2+ elevation in response to nicotine in PC12 cells was abolished by Na+ removal. The...

journal_title：Neuroreport

authors： Krjukova J,Akerman KE

更新日期：2002-07-02 00:00:00

abstract：:It is known that interleukin-1beta facilitates pain, but the mechanisms of this are not understood. This study investigated the role of interleukin-1beta in the expression of Fos, a marker of neuronal activation, and hyperalgesia caused by injecting complete Freund's adjuvant into one hind paw of the rat. Interleukin-...

journal_title：Neuroreport

authors： Li A,Lao L,Wang Y,Zhang H,Ren K,Berman BM,Zhang R

更新日期：2007-03-26 00:00:00

abstract：:GLYX-13 (threonine-proline-proline-threonine-amide) is an amidated di-pyrrolidine that acts as a functional partial agonist at the glycine site on N-methyl-D-aspartate glutamate receptors (NMDARs). GLYX-13 can both increase NMDAR conductance at NR2B-containing receptors, and reduce conductance of non-NR2B-containing r...

journal_title：Neuroreport

authors： Stanton PK,Potter PE,Aguilar J,Decandia M,Moskal JR

更新日期：2009-08-26 00:00:00

abstract：:Multiple signal classification is an alternative to the traditional dipole fitting source analysis methods. Our aim was to assess the clinical usefulness of this algorithm and to compare the localization of the epileptiform electroencephalography discharges with the regions of altered cerebral blood flow in 10 patient...

journal_title：Neuroreport

authors： Beniczky S,Oturai PS,Alving J,Sabers A,Herning M,Fabricius M

更新日期：2006-08-21 00:00:00

abstract：:The immediate-early genes, especially c-fos, have been suggested to have an important role in neuronal plasticity and memory. However, it has been difficult to determine if in fact c-fos can participate in control of behaviour. Here we can report that direct unilateral infusion into the rat neostriatum of an antisense...

journal_title：Neuroreport

authors： Sommer W,Bjelke B,Ganten D,Fuxe K

更新日期：1993-12-13 00:00:00

abstract：:Stimulation of the Schaffer collateral projection to the CA1 region in rat hippocampal slices at 1 Hz for 15 min produced a N-methyl-D-aspartate (NMDA) receptor-dependent long-term depression (LTD) of synaptic responses and, when given after tetanic stimulation, reversed long-term potentiation (LTP). Both LTD and the ...

journal_title：Neuroreport

authors： Izumi Y,Zorumski CF

更新日期：1993-09-01 00:00:00

abstract：:We examined the effect of stimulus interruption on dual component field EPSPs in the hippocampal CA1 region. Resuming test stimulation at 0.1 Hz after 10-60 min silent periods led to an increase of the response followed by a decline, involving AMPA and NMDA components to a similar extent. Similar changes were seen whe...

journal_title：Neuroreport

authors： Niu YP,Xiao MY,Karpefors M,Wigström H

更新日期：1999-04-06 00:00:00

abstract：:The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

journal_title：Neuroreport

authors： O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

更新日期：2000-11-27 00:00:00

abstract：:There is no unifying hypothesis to account for the anatomical distribution of neuropathology, the involvement of beta-amyloid precursor protein (beta APP) and the role of increasing age in triggering the Alzheimer disease process. We report here that layer II pre-alpha neurones in transentorhinal and entorhinal cortex...

journal_title：Neuroreport

authors： Roberts GW,Nash M,Ince PG,Royston MC,Gentleman SM

更新日期：1993-01-01 00:00:00

abstract：:In primary cultures from rat cerebral cortex, pituitary adenylate cyclase-activating polypeptide (PACAP-38) exerted a protective effect on cell death induced by the excitotoxin NMDA in neuron-enriched cultures and also on apoptotic cell death induced by serum deprivation in mixed neuronal-glial cultures. The neuroprot...

journal_title：Neuroreport

authors： Frechilla D,García-Osta A,Palacios S,Cenarruzabeitia E,Del Rio J

更新日期：2001-04-17 00:00:00

abstract：:Currents from the slowly adapting stretch receptor neuron of the crayfish (Pacifastacus leniusculus) were studied in a cell attached configuration using patch pipettes with an opening diameter of 2-10 microm. The neuronal membrane was enzymatically freed from the glial layer. The voltage gated Na+ and K+ channels seem...

journal_title：Neuroreport

authors： Lin JH,Sand P,Rydqvist B

更新日期：1999-08-20 00:00:00

abstract：:Transient receptor potential vanilloid 1 (TRPV1) channel has been found to be expressed in a variety of tissues over the last few years, including the central nervous system (CNS). However, the distribution of TRPV1 in the CNS remains a controversial question. Here, we reveal that the expression of TRPV1 can be detect...

journal_title：Neuroreport

authors： Huang WX,Min JW,Liu YQ,He XH,Peng BW

更新日期：2014-04-16 00:00:00

abstract：:Altered glutamate signaling is associated with Parkinson's disease. To study the involvement of the cystine/glutamate antiporter in the pathogenesis of Parkinson's disease, we developed new polyclonal antibodies recognizing xCT, the specific subunit of this antiporter. The striatal xCT protein expression level was inv...

journal_title：Neuroreport

authors： Massie A,Schallier A,Mertens B,Vermoesen K,Bannai S,Sato H,Smolders I,Michotte Y

更新日期：2008-10-29 00:00:00

abstract：:Cultured and transplanted adrenal medullary cells respond to ciliary neurotrophic factor (CNTF) with neurite formation and improved cell survival although the presence of the CNTF receptor-alpha (CNTFRalpha) has been unclear. This study show that CNTFRalpha mRNA was expressed in the postnatal day 1 as well as in the a...

journal_title：Neuroreport

authors： Förander P,Brené S,Strömberg I

更新日期：2000-02-28 00:00:00

abstract：:We examined the effect of long-term potentiation (LTP) on paired-pulse responses across varied stimulus intensities and interstimulus intervals (ISIs), at ascending synapses from the intermediate and ventral hippocampus to the medial prefrontal cortex in urethane-anesthetized rats. LTP significantly shifted the median...

journal_title：Neuroreport

authors： Takita M,Izaki Y,Kuramochi M,Yokoi H,Ohtomi M

更新日期：2010-01-06 00:00:00

abstract：:Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg mo...

journal_title：Neuroreport

authors： Sharpe LG,Jaffe JH

更新日期：1990-09-01 00:00:00

abstract：:Voltage-gated sodium channels (VGSCs) are concentrated in the postsynaptic membrane at the adult rat neuromuscular junction (NMJ). We have used immunolabelling to determine the pattern of initial VGSC accumulation during development. At birth, but not 3 days before, VGSC labelling is detectable at the NMJ and in the p...

journal_title：Neuroreport

authors： Wood SJ,Shewry K,Young C,Slater CR

更新日期：1998-06-22 00:00:00