Synaptic plasticity dynamics in the hippocampal-prefrontal pathway in vivo.

abstract：:For the majority of neurones in cat striate cortex, the response to an optimal stimulus presented to one eye is suppressed when a stimulus of substantially different orientation is presented to the other eye. In order to determine the true orientational tuning of the underlying inhibitory interactions in the absence o...

journal_title：Neuroreport

authors： Sengpiel F,Freeman TC,Blakemore C

更新日期：1995-11-13 00:00:00

abstract：:Brain membrane phospholipid fatty acid composition is investigated in Alzheimer's disease using fresh pathologically proven autopsy material. The most striking abnormalities in Alzheimer brains compared to age-matched controls are found in the n - 6 line of polyunsaturated fatty acids (PUFA) showing an elevation of 18...

journal_title：Neuroreport

authors： Nakada T,Kwee IL,Ellis WG

更新日期：1990-10-01 00:00:00

abstract：:This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...

journal_title：Neuroreport

authors： Yan H,Zhang HY,Tang XC

更新日期：2007-05-07 00:00:00

abstract：:We examined the protective effects of N-acetylcysteine (NAC) on the death of glia-free neurons in culture. Under normoxic conditions, the protection by NAC was observed only in cystine-free but not complete medium. When the cells were cultured under hypoxic conditions, NAC much elongated their survival even in the pre...

journal_title：Neuroreport

authors： Sagara J,Bannai S,Shikano N,Makino N

更新日期：2010-04-21 00:00:00

abstract：:We investigated the protective effects of edaravone, a free radical scavenger, against ischemic damage of inner hair cells (IHCs) in gerbils. Cochlear ischemia was induced in the animals by occluding the vertebral arteries bilaterally for 15 min. Edaravone (1 mg/kg, i.v.) or saline was administered 1 h after ischemia....

journal_title：Neuroreport

authors： Maetani T,Hakuba N,Taniguchi M,Hyodo J,Shimizu Y,Gyo K

更新日期：2003-10-06 00:00:00

abstract：:The hypothesis that sleep participates in the consolidation of recent memory traces has been investigated using four main paradigms: (1) effects of post-training sleep deprivation on memory consolidation, (2) effects of learning on post-training sleep, (3) effects of within sleep stimulation on the sleep pattern and o...

journal_title：Neuroreport

authors： Peigneux P,Laureys S,Delbeuck X,Maquet P

更新日期：2001-12-21 00:00:00

abstract：:Neurotrophins are promising candidates to slow the progression of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease in which spinal and cortical motoneurons selectively degenerate. In a long-term in vitro model, malonate-induced toxicity and cell death of motoneurons have been demonstrated. Here we stud...

journal_title：Neuroreport

authors： Van Westerlaak MG,Bär PR,Cools AR,Joosten EA

更新日期：2001-05-25 00:00:00

abstract：:Synaptic or 'hard wired' neurotransmission in the brain, subject to modulation by a class of substances called modulators, has been the dominant model of brain function. However, increasing evidence for alternate non-synaptic neurotransmission mechanisms is forcing consideration of a more inclusive model. Evidence is ...

journal_title：Neuroreport

authors： Bach-y-Rita P

更新日期：1993-04-01 00:00:00

abstract：:In the present study, we tested the hypothesis that interleukin (IL)-10 down-regulates human microglial cell IL-8 release by inhibiting activation of nuclear factor kappa B (NF-kappaB). Immunohistochemical staining demonstrated that IL-10 markedly suppressed lipopolysaccharide (LPS)- and IL-1beta-stimulated IL-8 expre...

journal_title：Neuroreport

authors： Ehrlich LC,Hu S,Peterson PK,Chao CC

更新日期：1998-06-01 00:00:00

abstract：:Retinal gamma-aminobutyric acid type C (GABA[C]) receptors are believed to consist of rho subunits. The pharmacological properties of GABA(C) receptors appear to vary among different species. Since the mouse is an important model for gene targeting and behavioral studies, this study was aimed at cloning rho subunits i...

journal_title：Neuroreport

authors： Greka A,Koolen JA,Lipton SA,Zhang D

更新日期：1998-01-26 00:00:00

abstract：:Physical exercise has many health benefits, including improved cardiovascular fitness, lean muscle development, increased metabolism, and weight loss, as well as positive effects on brain functioning and cognition. Recent evidence suggests that regular physical exercise may also affect the responsiveness of reward reg...

journal_title：Neuroreport

authors： Killgore WD,Kipman M,Schwab ZJ,Tkachenko O,Preer L,Gogel H,Bark JS,Mundy EA,Olson EA,Weber M

更新日期：2013-12-04 00:00:00

abstract：:The neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT) and transported into synaptic vesicles by the vesicular acetylcholine transporter (VAChT). Recently it has been reported that the entire coding region of VAChT mRNA is located in the first intron of the ChAT gene. In this study, ChAT...

journal_title：Neuroreport

authors： Misawa H,Takahashi R,Deguchi T

更新日期：1995-05-09 00:00:00

abstract：:Three adult Japanese monkeys (M. fuscata: body weights 4.5-8.5 kg) were trained to walk quadrupedally on a surface of a moving treadmill (walking length and width: 150 cm and 60 cm, treadmill speed: 0.4-1.7 m s-1. At any different constant treadmill velocity, the monkeys exhibited a diagonal pattern of locomotor movem...

journal_title：Neuroreport

authors： Mori S,Miyashita E,Nakajima K,Asanome M

更新日期：1996-10-02 00:00:00

abstract：:Deficits in processing of auditory stimuli are known to play an important role in the aetiology of dyslexia. To specify the auditory deficit in children at risk for dyslexia, 19 children with a phonological deficit and 15 controls were tested using the mismatch negativity event-related potential, which reflects preatt...

journal_title：Neuroreport

authors： Bitz U,Gust K,Spitzer M,Kiefer M

更新日期：2007-06-11 00:00:00

abstract：:The regional distribution of c-Fos expression in the brain after the administration of two tremorgenic agents was studied. In both the harmaline- and oxotremorin-treated rats, c-Fos-positive neurons were extensively distributed in the basal ganglia nuclei and the cerebellum. Additionally, in the harmaline-treated rats...

journal_title：Neuroreport

authors： Miwa H,Nishi K,Fuwa T,Mizuno Y

更新日期：2000-08-03 00:00:00

abstract：:The alpha 2-macroglobulin receptor/low-density lipoprotein receptor-related protein (alpha 2-M-R/LRP) is a multifunctional receptor which has been implicated in lipoprotein metabolism, clearance of proteinase-proteinase inhibitor complexes and regulation of growth factor/cytokine metabolism. This receptor is abundantl...

journal_title：Neuroreport

authors： Birkenmeier G,Grosche J,Reichenbach A

更新日期：1996-12-20 00:00:00

abstract：:Widespread invasiveness, represented by the invasion and migration, is the most important characteristic of glioblastoma multiforme (GBM) and is the main reason for therapeutic failure and recurrence of the tumor. Hypoxia is one of the main microenvironment in determining tumor invasiveness. Therefore, intense efforts...

journal_title：Neuroreport

authors： Huang W,Ding X,Ye H,Wang J,Shao J,Huang T

更新日期：2018-12-12 00:00:00

abstract：:Functional neuroimaging studies of handedness have traditionally focused on exploring regionally activated discrepancies, yet little is known regarding the effect of handedness on functional connections of brain regions. Here, we reported the relationship between cerebellar functional connectivity patterns and handedn...

journal_title：Neuroreport

authors： He Y,Zang Y,Jiang T,Gong G,Xie S,Xiao J

更新日期：2006-01-23 00:00:00

abstract：:Demyelinated CNS axons can be remyelinated by Schwann cells. A recent study concluded that with time Schwann cell remyelination is replaced by oligodendrocyte remyelination [9]. To examine this, the extent of Schwann cell and oligodendrocyte remyelination at 4, 6.5 and 24 weeks was determined for ethidium bromide lesi...

journal_title：Neuroreport

authors： Gilson JM,Blakemore WF

更新日期：2002-07-02 00:00:00

abstract：:Two patterns of neuronal firing, bursting and regular spiking, are observed in the somatosensory cortex of anesthetized rats. The effects of excitatory amino acid receptor agonists and antagonists on these discharge types have been examined in vivo, in order to assess their involvement in the generation of such firing...

journal_title：Neuroreport

authors： Kobayashi T,Nagao T,Fukuda H,Hicks TP,Oka JI

更新日期：1993-06-01 00:00:00

abstract：:Bicuculline- and baclofen-insensitive GABA receptors (GABAC receptors) on bipolar cells acutely dissociated from carp retina were investigated with using the whole-cell patch-clamp recording technique. The currents of these cells mediated by GABAC receptors showed striking desensitization, even at low concentrations o...

journal_title：Neuroreport

authors： Han MH,Li Y,Yang XL

更新日期：1997-04-14 00:00:00

abstract：:Leptin in the rat's nucleus accumbens (NAcc) core has previously shown to disrupt the effects of acute administration of cocaine on both locomotor activity and the phosphorylation levels of glycogen synthase kinase 3β. In the present study, we further measured the phosphorylation levels of GluA1 after bilateral microi...

journal_title：Neuroreport

authors： Lee JW,Kim WY,Kim JH

更新日期：2018-04-11 00:00:00

abstract：:Chronic nicotine exposure enhances axon reflexes in adult rats. Since smoking mothers expose their infants to nicotine, this study investigated whether late gestational and or lactational maternal nicotine exposure affects neonatal axon reflexes. Osmotic pumps, implanted subcutaneously in adult female rats, delivered ...

journal_title：Neuroreport

authors： Grunfeld JA,Tiedemann GJ,Westerman RA

更新日期：1993-06-01 00:00:00

abstract：:Two voltage-activated Na+ channel blockers, lamotrigine and flunarizine were applied ionophoretically to extracellularly recorded dorsal horn neurones to assess effects on activation by noxious (mustard oil) and innocuous (brush) stimuli. Lamotrigine and flunarizine caused significantly greater reductions in mustard o...

journal_title：Neuroreport

authors： Blackburn-Munro G,Fleetwood-Walker SM

更新日期：1997-05-06 00:00:00

abstract：:Resident microglial cells contribute to activation and expansion of T cells under inflammatory conditions within the CNS. However, there is no evidence how interactions between microglia and T cells affect CNS inflammation. We evaluated the effect of glial cell-derived dendritic cells (GC-DC) in expanding and eliminat...

journal_title：Neuroreport

authors： Xu LY,Yang JS,Xiao BG

更新日期：2002-01-21 00:00:00

abstract：:The taste reactivity test was used to evaluate the ability of motion sickness to produce conditioned rejection reactions, a putative measure of nausea in rats. Following three conditioning trials, rats displayed conditioned rejection reactions during an intraoral infusion of a rotation-paired saccharin solution. This ...

journal_title：Neuroreport

authors： Cordick N,Parker LA,Ossenkopp KP

更新日期：1999-05-14 00:00:00

abstract：:We investigated the roles of the auditory cortex in discrimination learning of vowel-like sounds consisting of multiple formants. Rats were trained to discriminate between synthetic sounds with four formants. Bilateral electrolytic lesions including the primary auditory cortex and the dorsal auditory association corte...

journal_title：Neuroreport

authors： Kudoh M,Nakayama Y,Hishida R,Shibuki K

更新日期：2006-11-27 00:00:00

abstract：:We localized the gene expression of angiotensin II receptor subtypes (AT1A, AT1B, and AT2) in 2-week-old rat brain by in situ hybridization using subtype specific riboprobes. AT1A receptor mRNA but not AT1B or AT2 receptor mRNA was expressed in the subfornical organ and paraventricular nucleus of the hypothalamus. AT1...

journal_title：Neuroreport

authors： Johren O,Inagami T,Saavedra JM

更新日期：1995-12-15 00:00:00

abstract：:Evidence exists that motilin immunoreactivity is highly expressed in Purkinje cells. In this study, immunohistochemistry and whole-cell patch-clamp recording were performed to investigate the spatial distribution and electrophysiological effects of motilin receptors in the cerebellum. We show here that motilin recepto...

journal_title：Neuroreport

authors： Chen H,Chen L,Wang JJ,Wei HJ,Yung WH

更新日期：2007-08-27 00:00:00

abstract：:A lexical decision experiment was conducted while event related potentials (ERPs) were recorded. The word frequency and the first syllable frequency of each word were manipulated. Results showed that, while high frequency words produced less negative amplitudes in the N400 time window than low frequency words, the inv...

journal_title：Neuroreport

authors： Barber H,Vergara M,Carreiras M

更新日期：2004-03-01 00:00:00