Conflicting effects of N-acetylcysteine on purified neurons derived from rat cortical culture.

abstract：:We have reported that corticotropin-releasing factor (CRF) receptor subtypes, CRF1 and CRF2, are involved in stress-induced anorexia. To clarify in which brain regions the CRF receptor is involved in mediating stress-induced anorexia, we examined the effect of microinjecting CRF1-selective or CRF2-selective antagonist...

journal_title：Neuroreport

authors： Ohata H,Shibasaki T

更新日期：2011-07-13 00:00:00

abstract：:The effects of copper on voltage-gated A-type potassium currents were investigated in acutely dissociated rat hippocampal CA1 neurons using the whole-cell patch-clamp technique. Extracellular application of various concentrations of copper (1-1000 microM) reversibly reduced the amplitude of voltage-gated A-type potass...

journal_title：Neuroreport

authors： Niu ZD,Yu K,Gu Y,Wang M,She JQ,Chen WH,Ruan DY

更新日期：2005-09-28 00:00:00

abstract：:Metabolic hypofunction is a common finding in a number of neurodegenerative diseases, including Alzheimer's disease (AD). The strong linkage between the amyloid precursor protein (APP) and AD led us to examine whether over-expression of this protein in CNS-type cells had an effect on mitochondria. We found abnormal mo...

journal_title：Neuroreport

authors： Grant SM,Shankar SL,Chalmers-Redman RM,Tatton WG,Szyf M,Cuello AC

更新日期：1999-01-18 00:00:00

abstract：:The effects of high frequency repetitive transcranial magnetic stimulation on sensory perception and the pain tolerance thresholds were investigated applying both motor cortex stimulation and medial frontal cortex stimulation in normal study participants. Both the sensory perception and pain tolerance thresholds were ...

journal_title：Neuroreport

authors： Yoo WK,Kim YH,Doh WS,Lee JH,Jung KI,Park DS,Park ES

更新日期：2006-02-06 00:00:00

abstract：:NMDA receptors (NR) are important in many neurological processes. Using a large series of human brain tissue, we show that the distribution of NR2A/B immunoreactivity varies according to position along a gyrus. For pyramidal neurons in laminae II and III, immunoreactivity is most marked at gyral crown and gyral lips, ...

journal_title：Neuroreport

authors： Sisodiya SM,Heffernan J,Harrison PJ,Squier MV,Thom M

更新日期：2000-08-03 00:00:00

abstract：:We examined the induction of progesterone receptor-immunoreactive (PR-ir) cells by estrogen in the rat preoptic area and ventromedial hypothalamic nucleus. Ovariectomized young (3-month-old) and old (24-month-old) female rats were treated with estrogen or cholesterol for 4 days. Estrogen significantly increased PR-ir ...

journal_title：Neuroreport

authors： Furuta M,Fukushima A,Chiba S,Sano A,Akema T,Kimura F,Funabashi T

更新日期：2010-08-04 00:00:00

abstract：:Reading demands precise and efficient letter and word processing. This event-related potentials (ERP) study utilized massive repetition of visually presented single letters to trigger neuronal adaptation. Our aim was to explore whether the adaptation pattern of the N170 ERP component, serving as an indicator of neuron...

journal_title：Neuroreport

authors： Korinth SP,Sommer W,Breznitz Z

更新日期：2013-01-23 00:00:00

abstract：:Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system, and humoral immunity is suggested to play an important role in the pathogenesis. The identification of an anti-aquaporin-4 antibody (AQP4-Ab, neuromyelitis optica immunoglobulin G) in the sera of patients with NMO has le...

journal_title：Neuroreport

authors： Kinoshita M,Nakatsuji Y,Moriya M,Okuno T,Kumanogoh A,Nakano M,Takahashi T,Fujihara K,Tanaka K,Sakoda S

更新日期：2009-03-25 00:00:00

abstract：:Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...

journal_title：Neuroreport

authors： Urbano A,Babiloni F,Babiloni C,Ambrosini A,Onorati P,Rossini PM

更新日期：1997-10-20 00:00:00

abstract：:Autophosphorylation of the alpha-isoform of Ca2+/calmodulin-dependent kinase II switches the kinase into an autonomous activity mode. This molecular switch is important for hippocampal long-term memory formation, which requires de novo gene transcription and protein synthesis. Here, we have studied whether auto-phosph...

journal_title：Neuroreport

authors： von Hertzen LS,Giese KP

更新日期：2005-08-22 00:00:00

abstract：:Cyclin-dependent kinases (CDK) mediate the cell division cycle during G1 phase and CDK inhibitors negatively regulate the cell cycle. We investigated expression of the CDK inhibitor p27Kip1 and the effects of PI-3K/Akt on proliferation of progenitors in the subventricular zone of adult rat. Western blots and immunosta...

journal_title：Neuroreport

authors： Zhang R,Zhang Z,Tsang W,Wang L,Chopp M

更新日期：2004-08-06 00:00:00

abstract：:We examined the biology of AMPA/kainate-induced motor neuron degeneration using dissociated spinal cord cultures and motor neuron-specific antibodies which enable characterization of individual motor neurons in culture. Cobalt, which is thought to pass through Ca2+-permeable AMPA/kainate receptors following kainate ex...

journal_title：Neuroreport

authors： Bar-Peled O,O'Brien RJ,Morrison JH,Rothstein JD

更新日期：1999-03-17 00:00:00

abstract：:To determine whether EEG synchronization in sleep has a metabolic equivalent, we investigated state-dependent changes in extracellular concentrations of amino acids. In vivo microdialysis studies were performed in the ventroposterolateral (VPL) nuclei of the thalamus of cats during natural slow wave sleep (SWS), wakin...

journal_title：Neuroreport

authors： Kékesi KA,Dobolyi A,Salfay O,Nyitrai G,Juhász G

更新日期：1997-03-24 00:00:00

abstract：:The diversion of attention from a primary goal by irrelevant events is known as attention capture, and is often followed by a directed action. The hypothesis that corticospinal excitability is modulated by attention capture was tested using transcranial magnetic stimulation. Participants watched a video while sounds w...

journal_title：Neuroreport

authors： Mock JR,Foundas AL,Golob EJ

更新日期：2011-11-16 00:00:00

abstract：:Cerebral blood flow (CBF) was measured at varying haematocrit values in 8 streptozotocin-diabetic and in 7 control rats using the intracarotid 133Xe technique. A hyperbolic relationship between CBF and haematocrit was established for the individual rats in both groups. Diabetic animals showed a preserved CBF response ...

journal_title：Neuroreport

authors： Knudsen GM,Tedeschi E,Jakobsen J

更新日期：1992-11-01 00:00:00

abstract：:Sulphated cholecystokinin-8 (CCK-8) given into the neostriatum of the rat by in vivo microdialysis produced a concentration-dependent (1-100 microM) increase in extracellular aspartate (Asp) and dynorphin B (Dyn B), but not in glutamate, GABA or dopamine levels. The increase in Asp levels produced by 10 microM CCK-8 w...

journal_title：Neuroreport

authors： You ZB,Pettersson E,Herrera-Marschitz M,Hökfelt T,Terenius L,Nylander I,Goiny M,Hughes J,O'Connor WT,Ungerstedt U

更新日期：1994-11-21 00:00:00

abstract：:Human morning/evening preferences has recently been reported to be associated with polymorphism of the 3' flanking region of the Clock gene, which was the first identified mammalian circadian clock gene. We recorded body temperature, spontaneous activity, electroencephalogram and electromyogram for 48 h in mice with J...

journal_title：Neuroreport

authors： Sei H,Oishi K,Morita Y,Ishida N

更新日期：2001-05-25 00:00:00

abstract：:Bilabial, alveolar and velar sounds are produced at different locations around the oral cavity. fMRI was used to localize cortical representation of articulation in seven healthy subjects during repetitive lip and vertical tongue movements as well as repetitive articulation of /pa/ (bilabial), /ta/ (alveolar), /ka/ (v...

journal_title：Neuroreport

authors： Lotze M,Seggewies G,Erb M,Grodd W,Birbaumer N

更新日期：2000-09-11 00:00:00

abstract：:This study was designed to investigate the expression of transient receptor potential melastatin 3 (TRPM3) and transient receptor potential vanilloid type 4 (TRPV4) in the trigeminal spinal subnucleus caudalis of a rat model of trigeminal neuralgia (TN). The influence of botulinum toxin type A (BTX-A) on the expressio...

journal_title：Neuroreport

authors： Zhang Y,Su Q,Lian Y,Chen Y

更新日期：2019-07-03 00:00:00

abstract：:The cochlea can be protected from acoustic trauma by moderate-level sound exposure. It is suggested that olivocochlear system may play a significant role in this protection. This study was performed to investigate distortion product otoacoustic emission (DPOAE) amplitudes changes and the efficiency of contralateral no...

journal_title：Neuroreport

authors： Peng JH,Tao ZZ,Huang ZW

更新日期：2007-07-16 00:00:00

abstract：:The role of dopaminergic pathways in the retina in controlling the functional state of the pineal was investigated. Dopaminergic agents were injected into the eyes of dark-adapted chickens which were maintained in the dark. Changes in the activity of N-acetyltransferase (NAT) in the retina and pineal were then monitor...

journal_title：Neuroreport

authors： Morgan IG,Boelen MK,Miethke P

更新日期：1995-02-15 00:00:00

abstract：:Areas of the brain's left hemisphere involved in retrieving words with emotional connotations were studied with fMRI. Participants silently generated words from different semantic categories which evoked either words with emotional connotations or emotionally neutral words. Participants repeated emotionally neutral wo...

journal_title：Neuroreport

authors： Crosson B,Radonovich K,Sadek JR,Gökçay D,Bauer RM,Fischler IS,Cato MA,Maron L,Auerbach EJ,Browd SR,Briggs RW

更新日期：1999-08-20 00:00:00

abstract：:Birds are capable of dexterous sensory-motor activities such as tool use. Reaching is a crucial component of tool use and is a vision-guided behavior in primates, in which arm movement is monitored online in a stable visual frame. However, vision-guided reaching in primates is enabled by anatomical separation of the h...

journal_title：Neuroreport

authors： Kanai M,Matsui H,Watanabe S,Izawa E

更新日期：2014-09-10 00:00:00

abstract：:The gene expression of cholecystokinin (CCK), a neuropeptide with anti-opioid properties, has been reported to be upregulated in some primary sensory neurons after a peripheral nerve lesion. We have recently demonstrated that the upregulation of CCK mRNA is not accompanied by an increased potassium-evoked release CCK-...

journal_title：Neuroreport

authors： Afrah AW,Gustafsson H,Olgart L,Brodin E,Stiller CO

更新日期：2001-01-22 00:00:00

abstract：:Recently, there has been growing interest in the neurobiological role of some amygdalar neuromediators, such as GABA and orexins (ORX), that are responsible for stressful behaviors. Infusion of the major fear-related and panic-related basolateral amygdalar station, the lateral nucleus, with ORX-A and ORX-B, alone or i...

journal_title：Neuroreport

authors： Avolio E,Biasone A,Mele M,Alò R

更新日期：2014-08-20 00:00:00

abstract：:In dorsal unpaired median (DUM) neurones isolated from the terminal ganglion of the cockroach Periplaneta americana two types of Ca2+ currents were found: a transient one activated by lower depolarizations (LVA) and a sustained one activated by higher voltage jumps (HVA). Both currents were strongly reduced by 100 mic...

journal_title：Neuroreport

authors： Wicher D,Penzlin H

更新日期：1994-05-09 00:00:00

abstract：:Retinal on-bipolar cells possess specialized glutamate receptors which are coupled via a G-protein to the control of a cyclic GMP (cGMP) cascade. Whole-cell voltage clamp recordings were obtained from light-responsive on-bipolar cells in retinal slices of the dogfish. Inclusion of nitroprusside in the patch-pipette so...

journal_title：Neuroreport

authors： Shiells R,Falk G

更新日期：1992-10-01 00:00:00

abstract：:The death of spinal motoneurones after axotomy provides a useful model for studying novel factors which prevent motoneurone loss in vivo. Peripheral nerves of newborn rats were unilaterally transected and treated with either a vehicle solution or leukaemia inhibitory factor (LIF). Compared with the vehicle controls, t...

journal_title：Neuroreport

authors： Cheema SS,Richards LJ,Murphy M,Bartlett PF

更新日期：1994-04-14 00:00:00

abstract：:Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson' disease motor imagery is impaired and that execution of overt movements is...

journal_title：Neuroreport

authors： Frak V,Cohen H,Pourcher E

更新日期：2004-06-28 00:00:00

abstract：:Electroencephalography (EEG) and gaze data have traditionally been separated in neurocognitive studies because of the artefacts that even small controlled eye movements produce. Study of gaze control in a visual tracking task provides information about an individual's prospective control. By including gaze events in t...

journal_title：Neuroreport

authors： Holth M,van der Meer AL,van der Weel FR

更新日期：2013-12-04 00:00:00