Leukaemia inhibitory factor rescues motoneurones from axotomy-induced cell death.

abstract：:Somatostatin sst2(a) receptor was observed, by immunofluorescence, in ependymal cells and in tanycytes of the wall of the ventricle and the hypothalamic recess of the male rat median eminence. Strong immunoreactivity for the receptor protein was observed in lateral tanycytes (alpha-type) while a moderate signal was se...

journal_title：Neuroreport

authors： Hashemi SH,Li JY,Schindler M,Dahlström A

更新日期：2001-07-03 00:00:00

abstract：:Integrating information across the senses can enhance our ability to detect and classify stimuli in the environment. For example, auditory speech perception is substantially improved when the speaker's face is visible. In an fMRI study designed to investigate the neural mechanisms underlying these crossmodal behaviour...

journal_title：Neuroreport

authors： Calvert GA,Brammer MJ,Bullmore ET,Campbell R,Iversen SD,David AS

更新日期：1999-08-20 00:00:00

abstract：:Emerging evidence has suggested that alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) protects neurons from glutamate-induced neurotoxicity. In this study, we examined the effect of AMPA on the cell surface expression of the N-methyl-D-aspartate (NMDA) receptor, a central player in glutamate-induced neurot...

journal_title：Neuroreport

authors： Nishimoto T,Kihara T,Akaike A,Niidome T,Sugimoto H

更新日期：2009-01-28 00:00:00

abstract：:Dopamine (DA) deficiency in Parkinson's disease is commonly treated with L-dihydroxyphenylalanine (L-dopa), the amino acid precursor to DA. L-dopa is neurotoxic in vitro and impairs survival of metabolically stressed neurons in vivo. We examined with microdialysis of substantia nigra in awake rats the local production...

journal_title：Neuroreport

authors： Smith TS,Parker WD Jr,Bennett JP Jr

更新日期：1994-04-14 00:00:00

abstract：:N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...

journal_title：Neuroreport

authors： Montag-Sallaz M,Montag D,Schachner M

更新日期：2003-07-18 00:00:00

abstract：:This study investigated whether mild birth complications (C-section birth, C-section + 15 min global anoxia) interact with stress at adulthood to modulate levels of [3H]WIN 35428 binding to dopamine transporters (DAT) in rat brain. Without stress, adult C-sectioned rats showed increased DAT binding in the dorsal stria...

journal_title：Neuroreport

authors： El-Khodor BF,Boksa P

更新日期：2002-02-11 00:00:00

abstract：:Cortical processes underlying perception of musical consonance were investigated by long-latency auditory evoked potentials (EPs). Subjects listened to a random sequence of dyadic pure tones paired at various pitch intervals (1, 4, 6, 7, or 9 semitones). Amplitudes of P2 and N2 components of auditory EPs were signific...

journal_title：Neuroreport

authors： Itoh K,Suwazono S,Nakada T

更新日期：2003-12-19 00:00:00

abstract：:Recent studies have shown the nutrient-sensing systems transmitting nutritive information from the gut to the brain. However neural activity evoked by ingested dietary nutrients has not been investigated adequately. Using functional magnetic resonance imaging, we demonstrated that rat forebrain responded to intragastr...

journal_title：Neuroreport

authors： Tsurugizawa T,Kondoh T,Torii K

更新日期：2008-07-16 00:00:00

abstract：:The effects of interleukin-1beta in the paraventricular nucleus or caudal arcuate nucleus on hypertensive and tachycardiac responses induced by excitation of the central amygdaloid nucleus were studied. We observed that microinjection of sodium glutamate into central amygdaloid nucleus resulted in hypertension and tac...

journal_title：Neuroreport

authors： Lu Y,Chen W,Zou CJ

更新日期：2002-03-25 00:00:00

abstract：:Brain trauma induces a multitude of reactions at molecular, cellular, and tissue levels, some of which are beneficial to recovery, whereas others are detrimental. Osteopontin (OPN), a glycosylated phosphoprotein, can be found in both the soluble form and as an extracellular matrix constituent in several tissues in the...

journal_title：Neuroreport

authors： Plantman S

更新日期：2012-08-01 00:00:00

abstract：:The interaction of vestibular inputs with different dynamic and spatial behavior, i.e., canal-otolith interaction, leads to spatio-temporal convergence. Vestibular neurons in the fastigial nucleus often exhibit spatio-temporal convergence. The present report demonstrates that the discharge rates of most vestibular neu...

journal_title：Neuroreport

authors： Wilden A,Glasauer S,Kleine JF,Büttner U

更新日期：2002-05-07 00:00:00

abstract：:Adrenomedullin (ADM) is a 52 amino acid peptide with multiple physiological functions and wide tissue distributions including brain. Recently, elevated plasma levels of ADM were found in patients with schizophrenia, bipolar affective disorder and autism, suggesting the involvement of ADM in the pathophysiology of ment...

journal_title：Neuroreport

authors： Huang CH,Chen ML,Tsai YL,Tsai MT,Chen CH

更新日期：2004-06-28 00:00:00

abstract：:The effect of an ischaemic focal cortical lesion on the excitability of surrounding and remote brain areas was investigated. Infarcts were produced photothrombotically in rat frontal cortex and brain excitability was assessed by a extracellular paired-pulse stimulation in coronal slices 7 days later. The cortical lesi...

journal_title：Neuroreport

authors： Buchkremer-Ratzmann I,Witte OW

更新日期：1997-01-20 00:00:00

abstract：:Neural cells have distinct responses to CNS injury; however, neural progenitor response to CNS injury is not yet documented. Stab injury combined with injection of bromodeoxyuridine (BrdU), a thymidine analog, into adult rat cortex above the lateral ventricle for 10 min resulted in activated microglia/macrophage infil...

journal_title：Neuroreport

authors： Tzeng SF,Wu JP

更新日期：1999-08-02 00:00:00

abstract：:Distracted driving remains a leading factor in fatal motor vehicle crashes, particularly in young drivers. Due to ongoing neuromaturation, attention capabilities are changing and improving throughout young adulthood. Here, we sought to bridge neuroscience with driving simulation by evaluating the effects of driving on...

journal_title：Neuroreport

authors： Banz BC,Wu J,Camenga DR,Mayes LC,Crowley MJ,Vaca FE

更新日期：2020-05-22 00:00:00

abstract：:Acid-sensing ion channels (ASICs) constitute a branch of the super-gene family of amiloride-sensitive sodium channels. So far five different ASICs have been cloned from mammalian tissues. They are activated by a drop of extracellular pH but differ with respect to effective agonist concentration, desensitization and mR...

journal_title：Neuroreport

authors： Gründer S,Geissler HS,Bässler EL,Ruppersberg JP

更新日期：2000-06-05 00:00:00

abstract：:In this study, an algorithm is introduced for the automatic detection and simultaneous topographic classification of interictal regional spike activity in pediatric surface EEG records. The algorithm is based on the classification of the topographic distribution of instantaneous power by means of a 'group' trained cla...

journal_title：Neuroreport

authors： Feucht M,Hoffmann K,Steinberger K,Witte H,Benninger F,Arnold M,Doering A

更新日期：1997-07-07 00:00:00

abstract：:It is not clear whether attention is necessary or not for consciousness. We studied the relationship between attention and consciousness by tracking their electrophysiological correlates. The participants attended to visual targets, ignored nontargets in the prespecified visual field and ignored all stimuli in the opp...

journal_title：Neuroreport

authors： Koivisto M,Revonsuo A

更新日期：2007-05-28 00:00:00

abstract：:The brain-derived neurotrophic factor (BDNF) affects the developing cerebellar granule cells. Exposure of 9-11-day-old primary cultures of rat cerebellar granule neurones for 3 h to a more depolarizing medium (additional 15-30 mM KCl) stimulated the release of glutamate and increased the BDNF mRNAs levels. This BDNF a...

journal_title：Neuroreport

authors： Favaron M,Manev RM,Rimland JM,Candeo P,Beccaro M,Manev H

更新日期：1993-09-03 00:00:00

abstract：:Prolonged activation of brain N-methyl-D-aspartic acid (NMDA) receptors increases intraneuronal (Ca2+) and nitric oxide (NO) synthesis, and may be responsible for neuronal death in acute brain insults and chronic neurodegenerative diseases. NO can be converted in vitro to toxic hydroxyl (OH) radical. Using microdialys...

journal_title：Neuroreport

authors： Hammer B,Parker WD Jr,Bennett JP Jr

更新日期：1993-10-25 00:00:00

abstract：:The effects of a pharmacological blockade of the periaqueductal grey of the midbrain (PAG) on the elicitability of vocal fold movements from the facial motor cortex on the one hand and the anterior cingulate cortex and dorsomedial hypothalamus on the other were studied in the squirrel monkey. PAG blockade abolished vo...

journal_title：Neuroreport

authors： Jürgens U,Zwirner P

更新日期：1996-11-25 00:00:00

abstract：:Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulati...

journal_title：Neuroreport

authors： Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio G

更新日期：2001-06-13 00:00:00

abstract：:Inhibitory deficits are one of the predominant causes of cognitive aging. This study examined age-related changes in response inhibition. In this study, young and older participants performed a bimanual/bipedal response inhibition task while we measured their brain activity via functional near-infrared spectroscopy. P...

journal_title：Neuroreport

authors： Kawai N,Nakata R,Kubo-Kawai N

更新日期：2020-10-07 00:00:00

abstract：:Alpha oscillations during cognitive performance have mostly been studied in memory and/or basic attention tasks. This study investigates task-related alpha power desynchronization during an attentional switching task requiring higher executive attentional control. Low 8-10 Hz and high 10-12 Hz alpha power responses ar...

journal_title：Neuroreport

authors： Verstraeten E,Cluydts R

更新日期：2002-04-16 00:00:00

abstract：:Peripheral nervous system injury may be corrected by surgical repair, but in many cases this is not possible and will result in loss of motor and sensory function. Schwann cells provide many neurotrophic signals essential for axon regeneration and immediately after injury inflammatory cytokines are released necessary ...

journal_title：Neuroreport

authors： Teare KA,Pearson RG,Shakesheff KM,Haycock JW

更新日期：2004-03-01 00:00:00

abstract：:To confirm neural plasticity of the mouse hippocampo-prefrontal cortex (PFC) pathway, paired-pulse facilitation (PPF) and long-term potentiation (LTP) induction were determined in the pathway. In addition, we tested whether the plasticity differs in projections of the pathway from the dorsal (upper) and ventral (lower...

journal_title：Neuroreport

authors： Izaki Y,Takita M,Nomura M

更新日期：2001-05-08 00:00:00

abstract：:During the development of central nervous system, radial glial cells support target-specific neuronal migration. We recently reported that after implantation of chitosan channels with complete spinal cord transection, the tissue bridging the spinal cord stumps contained axons and radial glial cells. The purpose of thi...

journal_title：Neuroreport

authors： Nomura H,Kim H,Mothe A,Zahir T,Kulbatski I,Morshead CM,Shoichet MS,Tator CH

更新日期：2010-09-15 00:00:00

abstract：:This study examined the hypothesis that cholinergic receptor mechanisms within the gigantocellular tegmental field (FTG) of the medial pontine reticular formation can cause state-dependent changes in the firing rates of parabrachial nuclear complex (PBNC) neurons. Using intact, unanesthetized cats, long-term recording...

journal_title：Neuroreport

authors： Gilbert KA,Lydic R

更新日期：1993-03-01 00:00:00

abstract：:Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...

journal_title：Neuroreport

authors： Yuan J,Young BJ,Martinus RD

更新日期：2006-02-27 00:00:00

abstract：:The present study aimed to confirm and extend the finding, suggested by the results of a previous study, of different auditory neural efferent functioning in musicians compared with non-musicians. The activity of the medial olivocochlear bundle (MOCB), an auditory efferent subsystem, was measured through the contralat...

journal_title：Neuroreport

authors： Micheyl C,Khalfa S,Perrot X,Collet L

更新日期：1997-03-03 00:00:00