Brain-based limitations in attention and secondary task engagement during high-fidelity driving simulation among young adults.

abstract：:Monoamine oxidase A (MAOA) enzymatically degrades biogenic amines such as norepinephrine, dopamine, and serotonin, and plays a key role in the regulation of their neurotransmission. Allelic variations at the MAOA locus have been implicated in the neurobiology of aggression and impulsivity. We investigated the possible...

journal_title：Neuroreport

authors： Lee BT,Ham BJ

更新日期：2008-03-26 00:00:00

abstract：:Sensory information from the genitourinary tract is transmitted to perineal muscle reflex circuits in the spinal cord and to the medullary reticular formation (MRF). This is the first report of a functional descending connection between neurons in the MRF and sensory inputs of the pudendal motoneuron reflex circuitry....

journal_title：Neuroreport

authors： Johnson RD,Hubscher CH

更新日期：1998-01-26 00:00:00

abstract：:The aim of this study was to define the effects of a potent inhibitor of tyrosine phosphatases, sodium orthovanadate (0.1-100 microM for up to 48 h), on dentate gyrus cells (DGC) in culture. Treatment with 100 microM orthovanadate evoked a delayed form of cell death. To examine the possible involvement of apoptosis in...

journal_title：Neuroreport

authors： Figiel I,Kaczmarek L

更新日期：1997-07-28 00:00:00

abstract：:It has recently been proposed that brain responses in the gamma-range (> 20 Hz) include information about specific cognitive processes in the human brain. Empirical data substantiating this assumption come from EEG and MEG recordings during visual and language processing. For example, 30 Hz activity has been found to ...

journal_title：Neuroreport

authors： Pulvermüller F,Lutzenberger W,Preissl H,Birbaumer N

更新日期：1995-10-23 00:00:00

abstract：:The hypothesis of a magnocellular channel deficit in dyslexia was tested. Subjects were 10-year-old dyslexics and normal readers. Psychophysical thresholds for luminance and chromatic contrasts were estimated using black and white and red and green sinusoidal gratings of various spatial frequencies, presented in stati...

journal_title：Neuroreport

authors： Bednarek DB,Grabowska A

更新日期：2002-12-20 00:00:00

abstract：:The functions of the fields of the mammalian auditory cortex in sound perception and recognition are unknown. We used Fos (a protein of the inducible immediate-early gene c-fos) as a cellular marker of activated brain areas to show in the mouse (Mus domesticus) that sound is processed differentially in auditory cortic...

journal_title：Neuroreport

authors： Fichtel I,Ehret G

更新日期：1999-08-02 00:00:00

abstract：:Amyotrophic lateral sclerosis is a devastating motor neuron disorder. Traditionally regarded as a 'neuron only' disease, recent evidence suggested that other cells contribute critically to the pathogenesis. This review provides a short synopsis of the role neuroinflammation and microglial cells play in the disease and...

journal_title：Neuroreport

authors： Weydt P,Möller T

更新日期：2005-04-25 00:00:00

abstract：:Recently, it has been shown that visual perception can be radically altered by signals of other modalities. For example, when a single flash is accompanied by multiple auditory beeps, it is often perceived as multiple flashes. This effect is known as the sound-induced flash illusion. In order to investigate the princi...

journal_title：Neuroreport

authors： Shams L,Ma WJ,Beierholm U

更新日期：2005-11-28 00:00:00

abstract：:Whole-cell recordings in voltage-clamp mode were performed on acutely isolated neurones from rat neocortex and neostriatum to examine the effects of the anticonvulsant phenytoin on a non-inactivating (persistent) Na+ current (INaP). INaP was chosen because it enhances neuronal excitability near firing threshold, which...

journal_title：Neuroreport

authors： Chao TI,Alzheimer C

更新日期：1995-09-11 00:00:00

abstract：:Functional homology between human and macaque visual cortices has provided an important cue to functional subdivisions of the human visual cortex, but it is unclear beyond V1. We estimated the sizes and the visual field eccentricity functions of the extrastriate visual areas of human brains using MRI and fMRI measurem...

journal_title：Neuroreport

authors： Ejima Y,Takahashi S,Yamamoto H,Fukunaga M,Tanaka C,Ebisu T,Umeda M

更新日期：2003-08-26 00:00:00

abstract：:The gene expression of cholecystokinin (CCK), a neuropeptide with anti-opioid properties, has been reported to be upregulated in some primary sensory neurons after a peripheral nerve lesion. We have recently demonstrated that the upregulation of CCK mRNA is not accompanied by an increased potassium-evoked release CCK-...

journal_title：Neuroreport

authors： Afrah AW,Gustafsson H,Olgart L,Brodin E,Stiller CO

更新日期：2001-01-22 00:00:00

abstract：:After amputation of an arm the sensory map of the body changes radically, causing the sensory input from face to 'invade' the original hand area in the brain. As a result, touching the face of the amputee evokes tactile sensations on the phantom. These sensory referrals from the face to phantom hand occur in a stable,...

journal_title：Neuroreport

authors： Ramachandran VS,Brang D,McGeoch PD

更新日期：2010-07-14 00:00:00

abstract：:Acute arthritis is associated with pain-related behavior, joint swelling and increased joint temperature. Arthritic animals exhibit a significant decrease in paw withdrawal latency 4, 5, 6, 7 and 8 h after induction of inflammation, when compared with baseline values, indicative of secondary hyperalgesia. Intra-articu...

journal_title：Neuroreport

authors： Lawand NB,Willis WD,Westlund KN

更新日期：1997-03-03 00:00:00

abstract：:Administration of either a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801 (dizocilpine), or a muscarinic antagonist, scopolamine, produces dose-related impairments in performance of a visual recognition memory task, delayed non-matching to sample (DNMS) with lists of 20 symbols, in rhesus monk...

journal_title：Neuroreport

authors： Matsuoka N,Aigner TG

更新日期：1996-01-31 00:00:00

abstract：:Low, nonsedative doses of γ-hydroxybutyric acid (GHB) produce short-term anterograde amnesia in humans and memory impairments in experimental animals. We have previously shown that acute systemic treatment of GHB in adolescent female rats impairs the acquisition, but not the expression, of contextual fear memory while...

journal_title：Neuroreport

authors： Ishiwari K,Sircar R

更新日期：2016-06-15 00:00:00

abstract：:Several neurophysiological studies have highlighted the role of the midbrain periaqueductal gray matter (PAG) in the initiation of vocalization in various animal species, from frogs to primates. With regard to humans, only two cases of complete mutism following a lesion to the PAG have been reported so far. This artic...

journal_title：Neuroreport

authors： Esposito A,Demeurisse G,Alberti B,Fabbro F

更新日期：1999-03-17 00:00:00

abstract：:We recorded event-related potentials (ERPs) in 2-month-old infants in two different states of alertness: awake and asleep. Syllables varying in vowel duration (long vs short) were presented in an oddball paradigm, known to elicit a mismatch brain response. ERPs of both groups showed a mismatch response reflected in a ...

journal_title：Neuroreport

authors： Friederici AD,Friedrich M,Weber C

更新日期：2002-07-19 00:00:00

abstract：:delta-9-Tetrahydrocannabinol (THC) is a major psychoactive component of cannabis. We have recently localized a receptor for THC in the forebrain and found in the caudate-putamen that its gene expression is modulated by glucocorticoids, dopamine and glutamate. Here, we report for the first time, using quantitative in s...

journal_title：Neuroreport

authors： Mailleux P,Verslype M,Preud'homme X,Vanderhaeghen JJ

更新日期：1994-06-02 00:00:00

abstract：:GLYX-13 (threonine-proline-proline-threonine-amide) is an amidated di-pyrrolidine that acts as a functional partial agonist at the glycine site on N-methyl-D-aspartate glutamate receptors (NMDARs). GLYX-13 can both increase NMDAR conductance at NR2B-containing receptors, and reduce conductance of non-NR2B-containing r...

journal_title：Neuroreport

authors： Stanton PK,Potter PE,Aguilar J,Decandia M,Moskal JR

更新日期：2009-08-26 00:00:00

abstract：:Caffeine is a widely self-administered psychostimulant with purported neuroprotective and procognitive effects in rodent models of aging. The cholinergic basal forebrain is important for arousal and attention and is implicated in age-related cognitive decline. Accordingly, we determined the effects of caffeine on chol...

journal_title：Neuroreport

authors： Reznikov LR,Pasumarthi RK,Fadel JR

更新日期：2009-12-09 00:00:00

abstract：:When we look at our spatial environment we have the feeling that the whole visual field is coloured, yet the density of cone photoreceptors decreases considerably as eccentricity increases. We investigated colour perception (coloured/noncoloured), colour naming and whether colour helps object recognition at eccentrici...

journal_title：Neuroreport

authors： Naïli F,Despretz P,Boucart M

更新日期：2006-10-23 00:00:00

abstract：:Peripheral nervous system injury may be corrected by surgical repair, but in many cases this is not possible and will result in loss of motor and sensory function. Schwann cells provide many neurotrophic signals essential for axon regeneration and immediately after injury inflammatory cytokines are released necessary ...

journal_title：Neuroreport

authors： Teare KA,Pearson RG,Shakesheff KM,Haycock JW

更新日期：2004-03-01 00:00:00

abstract：:Lesions involving the dorsolateral prefrontal lobes may produce deficits on conceptual reasoning (CR) tasks in humans. Such deficits can also occur with subcortical lesions involving the basal ganglia, thalamus, or cerebellum, suggesting a common, yet widespread, neural network supporting this executive function. Here...

journal_title：Neuroreport

authors： Rao SM,Bobholz JA,Hammeke TA,Rosen AC,Woodley SJ,Cunningham JM,Cox RW,Stein EA,Binder JR

更新日期：1997-05-27 00:00:00

abstract：:Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium. Repeated song presentations caused lower expression of th...

journal_title：Neuroreport

authors： Kato Y,Kato M,Hasegawa T,Okanoya K

更新日期：2010-04-21 00:00:00

abstract：:Emerging evidence has suggested that alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) protects neurons from glutamate-induced neurotoxicity. In this study, we examined the effect of AMPA on the cell surface expression of the N-methyl-D-aspartate (NMDA) receptor, a central player in glutamate-induced neurot...

journal_title：Neuroreport

authors： Nishimoto T,Kihara T,Akaike A,Niidome T,Sugimoto H

更新日期：2009-01-28 00:00:00

abstract：:Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

journal_title：Neuroreport

authors： Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

更新日期：1999-01-18 00:00:00

abstract：:Regional cerebral blood flow was measured with positron emission tomography in seven normal volunteers while they performed various script event verification tasks. The left frontal lobe, left anterior cingulate and the anterior part of the left superior temporal gyrus were more activated in the script event membershi...

journal_title：Neuroreport

authors： Partiot A,Grafman J,Sadato N,Flitman S,Wild K

更新日期：1996-02-29 00:00:00

abstract：:Calsenilin, a multifunctional Ca2+-binding protein, has been identified as an Alzheimer's disease-associated presenilin interactor. Here, we investigated the histochemical localization of calsenilin and its expression levels in the brains of sporadic Alzheimer's disease. Both messenger RNA and protein expression of ca...

journal_title：Neuroreport

authors： Jin JK,Choi JK,Wasco W,Buxbaum JD,Kozlowski PB,Carp RI,Kim YS,Choi EK

更新日期：2005-04-04 00:00:00

abstract：:Regulation of CNTF mRNA was investigated in primary cortical astrocytes cultured from newborn rats and in C6 glioma cells. Northern blot analysis indicated that semi-confluent astrocyte cell cultures. CNTF added to confluent astrocyte cultures down-regulated CNTF message in a dose-dependent fashion. In contrast, when ...

journal_title：Neuroreport

authors： Meyer V,Unsicker K

更新日期：1994-10-03 00:00:00

abstract：:In this study, we examined the expression of insulin-like growth factor I (IGF-I) and its receptor (IGF-IR) in dorsal root ganglia (DRG) neurons in two rodent models of nerve injury: sciatic nerve axotomy and streptozotocin-induced (STZ) painful diabetic neuropathy. We demonstrate that IGF-I and its receptor are prefe...

journal_title：Neuroreport

authors： Craner MJ,Klein JP,Black JA,Waxman SG

更新日期：2002-09-16 00:00:00