Effects of phenytoin on the persistent Na+ current of mammalian CNS neurones.

abstract：:Experimental and clinical studies have revealed that angiotensin II type 1 receptor blocker has protective effects against ischemic brain injury, but the mechanism is still obscure. Angiotensin II type 1 receptor blocker may also have effects on neurogenesis through the activation of unblocked angiotensin II type 2 re...

journal_title：Neuroreport

authors： Wakai T,Yoshioka H,Yagi T,Kato T,Kinouchi H

更新日期：2011-06-11 00:00:00

abstract：:We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and B6 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels...

journal_title：Neuroreport

authors： Kurth C,Wegerer V,Reulbach U,Lewczuk P,Kornhuber J,Steinhoff BJ,Bleich S

更新日期：2004-02-09 00:00:00

abstract：:Event-related potential studies have reported error-related negativity following both error commission and feedback indicating errors or monetary loss. The present study examined whether error-related negativities could be elicited by a predictive cue presented prior to both the decision and subsequent feedback in a g...

journal_title：Neuroreport

authors： Dunning JP,Hajcak G

更新日期：2007-11-19 00:00:00

abstract：:NONINVASIVE photolytic injury to targeted neuronal subpopulations in vivo causes unique, slowly progressive neuronal degeneration. To examine the mechanisms of degeneration toward development and transplantation studies, cytosolic calcium levels were measured in vitro from neocortical neurons after incorporation of ph...

journal_title：Neuroreport

authors： Sheen VL,Dreyer EB,Macklis JD

更新日期：1992-08-01 00:00:00

abstract：:The effect of Co-dergocrine (Hydergine) on acetylcholine (ACh) release in the striatum and hippocampus has been studied by means of brain microdialysis and compared to the effect of SKF 38393 and of LY 171555 selective D1 and D2 dopamine (DA) receptor agonists, respectively. Co-dergocrine (1 and 5 mg kg-1 i.p.) as wel...

journal_title：Neuroreport

authors： Imperato A,Obinu MC,Dazzi L,Carta G,Mascia MS,Casu MA,Gessa GL

更新日期：1994-02-24 00:00:00

abstract：:Neural imaging studies have shown that the brains of skilled musicians respond differently to musical stimuli than do the brains of non-musicians, particularly for musicians who commenced practice at an early age. Whether brain attributes related to musical skill are attributable to musical practice or are hereditary ...

journal_title：Neuroreport

authors： Pantev C,Roberts LE,Schulz M,Engelien A,Ross B

更新日期：2001-01-22 00:00:00

abstract：:We can report, that by the use of indirect immunofluorescence techniques, that rat spinal motoneurons contain galanin-like immunoreactivity (LI). Furthermore, that galanin and calcitonin gene-related peptide (CGRP)-LI coexist in a number of spinal motoneurons. Co-localization could be demonstrated as thoracic, lumbar ...

journal_title：Neuroreport

authors： Johnson H,Hökfelt T,Ulfhake B

更新日期：1992-04-01 00:00:00

abstract：:It is difficult to induce long-term potentiation (LTP) in CA1 of hippocampal slices from 120-day-old rats when a single 100 Hz, 1 s tetanus is administered in extracellular solution containing 2.0 mM calcium and 2.0 mM magnesium. However, in the presence of 2.5 mM calcium and 1.3 mM magnesium LTP is reliably induced b...

journal_title：Neuroreport

authors： Izumi Y,Zorumski CF

更新日期：1998-11-16 00:00:00

abstract：:The aim of this study is to investigate the neural mechanism of extending a brand in a specific product category to other product categories. Facing two sequential stimuli in pairs consisting of beverage brand names (stimulus 1) and product names (stimulus 2) in other categories, 16 participants were asked to indicate...

journal_title：Neuroreport

authors： Ma Q,Wang X,Dai S,Shu L

更新日期：2007-07-02 00:00:00

abstract：:Recently, there has been growing interest in the neurobiological role of some amygdalar neuromediators, such as GABA and orexins (ORX), that are responsible for stressful behaviors. Infusion of the major fear-related and panic-related basolateral amygdalar station, the lateral nucleus, with ORX-A and ORX-B, alone or i...

journal_title：Neuroreport

authors： Avolio E,Biasone A,Mele M,Alò R

更新日期：2014-08-20 00:00:00

abstract：:The spatial-temporal expression and function of Drosophila melanogaster homothorax (hth) and its vertebrate homologue Meis2 in the eye anlage show a high degree of evolutionary conservation. Both are expressed by progenitor cells ahead of the neurogenic wave front, promote rapid proliferation of these cells, and are d...

journal_title：Neuroreport

authors： Heine P,Dohle E,Schulte D

更新日期：2009-02-18 00:00:00

abstract：:The present paper reports how aluminium [Al(III)] at a concentration of 3.7 microM can activate the bovine erythrocytic enzyme acetylcholinesterase (AChE) by about 38% in vitro. This same activating effect was observed on AChE form human as well as from rat erythrocyte ghosts and murine neuroblastoma cells. The intera...

journal_title：Neuroreport

authors： Zatta P,Zambenedetti P,Bruna V,Filippi B

更新日期：1994-09-08 00:00:00

abstract：:We studied the involvement of norepinephrine in the medial prefrontal cortex in the rewarding/reinforcing effects of ethanol. We evaluated the effects of norepinephrine selective depletion in the medial prefrontal cortex of C57/BL6J inbred mice that are commonly used in molecular studies and are highly susceptible to ...

journal_title：Neuroreport

authors： Ventura R,De Carolis D,Alcaro A,Puglisi-Allegra S

更新日期：2006-11-27 00:00:00

abstract：:Cyclin-dependent kinases (CDK) mediate the cell division cycle during G1 phase and CDK inhibitors negatively regulate the cell cycle. We investigated expression of the CDK inhibitor p27Kip1 and the effects of PI-3K/Akt on proliferation of progenitors in the subventricular zone of adult rat. Western blots and immunosta...

journal_title：Neuroreport

authors： Zhang R,Zhang Z,Tsang W,Wang L,Chopp M

更新日期：2004-08-06 00:00:00

abstract：:Extracellular pH transients were evoked in rat hippocampal brain slices by activation of a monosynaptic inhibitory pathway following pharmacological blockade of glutaminergic transmission. Repetitive stimulation in stratum radiatum near the recording site in stratum pyramidale evoked an immediate alkaline shift which ...

journal_title：Neuroreport

authors： Kaila K,Paalasmaa P,Taira T,Voipio J

更新日期：1992-01-01 00:00:00

abstract：:The ATP-gated cation channel P2X3 is expressed selectively by rat sensory neurones, and may play a role in nociception by binding ATP released from damaged or inflamed tissues. However, the distribution of this channel in human sensory neurons is not known. Using a specific antibody, we have demonstrated intense P2X3 ...

journal_title：Neuroreport

authors： Yiangou Y,Facer P,Birch R,Sangameswaran L,Eglen R,Anand P

更新日期：2000-04-07 00:00:00

abstract：:To determine whether physical match between studied and tested items influences blood flow increases in the hippocampal formation associated with recognition memory, positron emission tomography (PET) was used to measure changes in regional cerebral blood flow while healthy volunteers made old/new judgements about lin...

journal_title：Neuroreport

authors： Schacter DL,Uecker A,Reiman E,Yun LS,Bandy D,Chen K,Cooper LA,Curran T

更新日期：1997-12-22 00:00:00

abstract：:Exposure of primary murine cortical neuron cultures to N-methyl-D-aspartate (NMDA) resulted in neuronal death as evidenced by release of lactate dehydrogenase (LDH) into the media. The addition of N-nitro-L-arginine (N-Arg) protected the neurons from death in a concentration-dependent manner when added after the NMDA,...

journal_title：Neuroreport

authors： Reif DW

更新日期：1993-05-01 00:00:00

abstract：:When we look at our spatial environment we have the feeling that the whole visual field is coloured, yet the density of cone photoreceptors decreases considerably as eccentricity increases. We investigated colour perception (coloured/noncoloured), colour naming and whether colour helps object recognition at eccentrici...

journal_title：Neuroreport

authors： Naïli F,Despretz P,Boucart M

更新日期：2006-10-23 00:00:00

abstract：:We examined the induction of progesterone receptor-immunoreactive (PR-ir) cells by estrogen in the rat preoptic area and ventromedial hypothalamic nucleus. Ovariectomized young (3-month-old) and old (24-month-old) female rats were treated with estrogen or cholesterol for 4 days. Estrogen significantly increased PR-ir ...

journal_title：Neuroreport

authors： Furuta M,Fukushima A,Chiba S,Sano A,Akema T,Kimura F,Funabashi T

更新日期：2010-08-04 00:00:00

abstract：:This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice ...

journal_title：Neuroreport

authors： Matsumoto M,Nakagawa T,Higashi T,Kim TS,Kojima K,Kita T,Sakamoto T,Ito J

更新日期：2005-05-31 00:00:00

abstract：:The benzodiazepine, lorazepam enhances the efficiency of local, inhibitory GABA(A) synapses in the cortex, which stabilize postsynaptic, excitatory activity by synchronizing their own discharges at around 40 Hz. Treatment with lorazepam has also been shown to adversely influence detection performance in perceptual tas...

journal_title：Neuroreport

authors： Elliott MA,Becker C,Boucart M,Müller HJ

更新日期：2000-10-20 00:00:00

abstract：:Brain activation of 11 healthy right-handed subjects was studied with magnetoencephalography to estimate individual hemispheric dominance for speech sounds. The auditory stimuli comprised binaurally presented Finnish vowels, tones, and piano notes in groups of two or four stimuli. The subjects were required to detect ...

journal_title：Neuroreport

authors： Gootjes L,Raij T,Salmelin R,Hari R

更新日期：1999-09-29 00:00:00

abstract：:The distribution of histamine H1, H3, dopamine D1 and D2 receptors in the brain was studied by receptor autoradiography using a high-sensitivity and high-resolution imaging plate system. [3H]Pyrilamine, [3H](R)alpha-methyl-histamine, [11C]SCH23390, and [11C]N-methylspiperone (or [11C]YM-09151-2) were used as ligands t...

journal_title：Neuroreport

authors： Yanai K,Ryu JH,Watanabe T,Iwata R,Ido T

更新日期：1992-11-01 00:00:00

abstract：:To investigate the neural substrates for the perception of motion and of position in depth, we examined the changes in regional cerebral blood flow during positional and motion stereopsis in humans by positron emission tomography. During positional stereopsis, the right striate and peristriate cortices (areas V1/V2 an...

journal_title：Neuroreport

authors： Nagahama Y,Takayama Y,Fukuyama H,Yamauchi H,Matsuzaki S,Magata Y,Shibasaki H,Kimura J

更新日期：1996-07-29 00:00:00

abstract：:Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural...

journal_title：Neuroreport

authors： Kéri S,Gulyás B

更新日期：2003-06-11 00:00:00

abstract：:We report two functional magnetic resonance imaging experiments which reveal similarities and differences between perceptual and imaginal networks within the single visual submodality of colour. The first experiment contrasted viewing of a coloured and grey-scale Mondrian display, while the second contrasted a relativ...

journal_title：Neuroreport

authors： Howard RJ,ffytche DH,Barnes J,McKeefry D,Ha Y,Woodruff PW,Bullmore ET,Simmons A,Williams SC,David AS,Brammer M

更新日期：1998-04-20 00:00:00

abstract：:To compare the effectiveness of cyclosporin-A (CsA) with methylprednisolone (MP) or a combination of both upon inhibition of lipid peroxidation (LP) after spinal cord (SC) injury, rats were treated with either CsA, MP, CSA+MP or vehicle starting 1 h after SC contusion at T9 level. LP was assessed 24h after injury by t...

journal_title：Neuroreport

authors： Diaz-Ruiz A,Rios C,Duarte I,Correa D,Guizar-Sahagun G,Grijalva I,Madrazo I,Ibarra A

更新日期：2000-06-05 00:00:00

abstract：:Animal studies have shown brain ischaemia to cause oxidative damage to DNA and activation of caspase-3, leading to apoptosis. These changes may be exacerbated by reperfusion. To assess caspase-3 activation after transient and permanent brain ischaemia in man, we examined brain tissue from patients who had experienced ...

journal_title：Neuroreport

authors： Love S,Barber R,Srinivasan A,Wilcock GK

更新日期：2000-08-03 00:00:00

abstract：:We investigated the effect of an NO synthase inhibitor, NG-monomethyl-L-arginine (L-NMMA), on the levels of endogenous GABA in the rat striatum using in vivo microdialysis. Rats were perfused with the artificial CSF containing L-NMMA (0.1, 0.3 and 1.0 mM) or its inactive isomer D-NMMA (1.0 mM) for 1 h. Infusion of L-N...

journal_title：Neuroreport

authors： Semba J,Sakai M,Miyoshi R,Kito S

更新日期：1995-07-10 00:00:00