Difference in cochlear efferent activity between musicians and non-musicians.

abstract：:Age-related depletion of androgens in men results in functional impairments in androgen-responsive tissues, such as the brain, resulting in increased risk for Alzheimer's disease. To investigate the relationship between normal age-related hormone loss and Alzheimer's disease risk, we evaluated the brain and serum leve...

journal_title：Neuroreport

authors： Rosario ER,Chang L,Beckett TL,Carroll JC,Paul Murphy M,Stanczyk FZ,Pike CJ

更新日期：2009-11-25 00:00:00

abstract：:Previous studies have shown that spatial memory retention is affected by the metabotropic glutamate receptor (mGluR) influencing agents (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) and trans-azetidine-2,4-dicarboxylic acid (tADA). In the present investigation we examined whether the mGluR antagonist MCPG (20 mM an...

journal_title：Neuroreport

authors： Wetzel W,Wagner T,Reymann KG,Riedel G

更新日期：1995-11-27 00:00:00

abstract：:This study tested the hypothesis that inhibition of nitric oxide synthase (NOS) in the medial pontine reticular formation (mPRF) would cause decreased acetylcholine (ACh) release. Microdialysis of cat mPRF permitted measurement of ACh during states of wakefulness, non-rapid eye movement (NREM) sleep and rapid eye move...

journal_title：Neuroreport

authors： Leonard TO,Lydic R

更新日期：1995-07-31 00:00:00

abstract：:Diffuse axonal injury (DAI) accounts for more than 50% of all traumatic brain injury. In response to the mechanical damage associated with DAI, the abnormal proteins produced in the neurons and axons, namely, β-APP and p-tau, induce endoplasmic reticulum (ER) stress. Curcumin, a major component extracted from the rhiz...

journal_title：Neuroreport

authors： Huang T,Zhao J,Guo D,Pang H,Zhao Y,Song J

更新日期：2018-05-23 00:00:00

abstract：:Clinical and experimental studies clearly demonstrate that prolonged seizures and status epilepticus induce neuronal cell death in the brain. Recent evidence suggests that induction of apoptosis contributes greatly to seizure-induced brain damage. We recently demonstrated that intrahippocampal delivery of botulinum ne...

journal_title：Neuroreport

authors： Manno I,Antonucci F,Caleo M,Bozzi Y

更新日期：2007-04-16 00:00:00

abstract：:Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's disease. However, the role of SIRT2 in oxidative stress-induced cell death has remained unclear. In this study, we investigated the roles of SIRT2 in...

journal_title：Neuroreport

authors： Nie H,Hong Y,Lu X,Zhang J,Chen H,Li Y,Ma Y,Ying W

更新日期：2014-08-06 00:00:00

abstract：:Using cRNA in situ hybridization, the regional distribution of mRNA encoding the human Y1 receptor was investigated in the normal human brain and compared with the autoradiographic distribution of putative Y1/[125I][Leu31,Pro34]PYY binding sites. Surprisingly, relatively high levels of Y1 receptor mRNA, distributed in...

journal_title：Neuroreport

authors： Jacques D,Tong Y,Dumont Y,Shen SH,Quirion R

更新日期：1996-04-10 00:00:00

abstract：:The current study investigated whether an ipsilesional bias in line bisection, a conventional measure for diagnosing hemispatial neglect, persists even in the absence of this syndrome in patients with chronic lesions restricted to posterior association cortex or dorsolateral prefrontal cortex. Both left and right hemi...

journal_title：Neuroreport

authors： Machado L,Rafal RD

更新日期：1999-10-19 00:00:00

abstract：:SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identifie...

journal_title：Neuroreport

authors： Fang ZX,Hong SQ,Li TS,Wang J,Xie LL,Han W,Jiang L

更新日期：2019-06-12 00:00:00

abstract：:Poly(ADP-ribose) polymerase-1 consumes NAD to catalyze poly(ADP-ribosyl)ation of target proteins, which modulates various biological functions. However, excessive poly(ADP-ribose) polymerase-1 activation mediates oxidative cell death. Our recent studies have indicated that NAD can enter into astrocytes to prevent poly...

journal_title：Neuroreport

authors： Zhu K,Swanson RA,Ying W

更新日期：2005-08-01 00:00:00

abstract：:The survival and differentiation of neuronal cells is dependent on factors such as neurotrophins, cytokines and components of extracellular matrix. Bone marrow stromal cells have been shown to support the growth and differentiation of neuroblastoma cells. In an attempt to study the effects of bone marrow stromal cells...

journal_title：Neuroreport

authors： Ho SH,So LH,Lai KO,Ip NY,Leung MF

更新日期：1998-05-11 00:00:00

abstract：:Transplanted olfactory ensheathing cells (OECs) have previously been demonstrated to support axonal growth and myelination in the adult rat CNS. Here, the capacity of donor OECs to control the direction of axonal regeneration has been investigated following transplantation, as elongated columns, into the thalamus of a...

journal_title：Neuroreport

authors： Pérez-Bouza A,Wigley CB,Nacimiento W,Noth J,Brook GA

更新日期：1998-09-14 00:00:00

abstract：:The effect of olfactory deprivation on cellular expression of the Bcl-2 gene in the olfactory bulb of young rats was investigated. Restriction of olfactory stimuli caused an overall increase in Bcl-2 mRNA expression, with increases seen in the lateral aspects of glomerular, external plexiform, mitral and granule cell ...

journal_title：Neuroreport

authors： Najbauer J,Ibrahim E,Leon M

更新日期：1995-12-29 00:00:00

abstract：:Deficits in auditory sensory memory at the electrophysiological level as indexed by mismatch negativity and those in auditory verbal memory at the neuropsychological level have been independently demonstrated in previous studies of schizophrenia. We predicted a specific association between these indices in schizophren...

journal_title：Neuroreport

authors： Kawakubo Y,Kasai K,Kudo N,Rogers MA,Nakagome K,Itoh K,Kato N

更新日期：2006-07-17 00:00:00

abstract：:The aim of this investigation was to study whether melatonin affects the release of oxytocin and vasopressin by the pituitary neurointermediate lobe of the Syrian hamster in vitro. The effect of melatonin was studied on the unstimulated (pre- and post-K+ -stimulated) release of oxytocin and vasopressin and on the resp...

journal_title：Neuroreport

authors： Juszczak M,Debeljuk L,Bartke A,Stempniak B

更新日期：1995-12-15 00:00:00

abstract：:The octave illusion is experienced when two simultaneous tones, separated by one octave and presented to the opposite ears, are continuously reversed between the two ears. Subjects consistently report a sequence of alternating single tones: the high tone in the right ear and the low in the left. We wished to determine...

journal_title：Neuroreport

authors： Ross J,Tervaniemi M,Näätänen R

更新日期：1996-12-20 00:00:00

abstract：:Flurothyl kindling initiates a time-dependent process that results in a facilitated propagation from the forebrain to the brainstem seizure system and in an increase in the complexity of behavioral seizure expression. We investigated the involvement of the ventromedial nucleus of the hypothalamus (VMH) in mediating th...

journal_title：Neuroreport

authors： Ferland RJ,Applegate CD

更新日期：1998-11-16 00:00:00

abstract：:beta-N-methylamino-L-alanine (L-BMAA) is an excitotoxin whose neurodegenerative effects are associated with its agonist properties at the N-methyl-D-aspartate (NMDA) receptor. We measured the effects of L-BMAA on inositol phosphate (InsP) formation in primary cultured striatal neurons. This culture is almost devoid of...

journal_title：Neuroreport

authors： Manzoni OJ,Prezeau L,Bockaert J

更新日期：1991-10-01 00:00:00

abstract：:Maintenance of long-term potentiation in perforant path-granule cell synapses is accompanied by increased glutamate release. Here we investigate the role of synaptophysin in release and in expression of long-term potentiation in dentate gyrus. We report that long-term potentiation was accompanied by increased endogeno...

journal_title：Neuroreport

authors： Mullany PM,Lynch MA

更新日期：1998-08-03 00:00:00

abstract：:This study examined the relationship between social anxiety and the neural processing of threat in faces. Twenty-one adults with different levels of society anxiety were tested for their event-related potential responses to unattended threatening and nonthreatening faces, presented upright and upside-down, at three po...

journal_title：Neuroreport

authors： Sewell C,Palermo R,Atkinson C,McArthur G

更新日期：2008-08-27 00:00:00

abstract：:delta-9-Tetrahydrocannabinol (THC) is a major psychoactive component of cannabis. We have recently localized a receptor for THC in the forebrain and found in the caudate-putamen that its gene expression is modulated by glucocorticoids, dopamine and glutamate. Here, we report for the first time, using quantitative in s...

journal_title：Neuroreport

authors： Mailleux P,Verslype M,Preud'homme X,Vanderhaeghen JJ

更新日期：1994-06-02 00:00:00

abstract：:The taste reactivity test was used to evaluate the ability of motion sickness to produce conditioned rejection reactions, a putative measure of nausea in rats. Following three conditioning trials, rats displayed conditioned rejection reactions during an intraoral infusion of a rotation-paired saccharin solution. This ...

journal_title：Neuroreport

authors： Cordick N,Parker LA,Ossenkopp KP

更新日期：1999-05-14 00:00:00

abstract：:The primate pulvinar connects with the entire array of known visual areas and is postulated to play a role in selective visual attention. Recently, five separate neurochemical subdivisions of a region termed the inferior pulvinar (PI) complex were identified in monkeys. In the present study, similar histochemical proc...

journal_title：Neuroreport

authors： Cola MG,Gray DN,Seltzer B,Cusick CG

更新日期：1999-12-16 00:00:00

abstract：:Voltage-gated K+ channels (K(V)) regulate cell electrical properties, proliferation, migration, and death. Rotenone is a mitochondrial inhibitor, influencing activity of many channels that potentially participate in cell death processes, but its effect on K(V) channel in neurons remains unclear. This study used whole-...

journal_title：Neuroreport

authors： Gao XF,Wang W,He C

更新日期：2008-09-17 00:00:00

abstract：:Recently, we have generated transgenic mice (designated as SJLB) carrying human N279K mutant tau, one of the tau mutations causing parkinsonism linked to chromosome 17 (FTDP-17). SJLB mice mimic some features of behavioral alterations and neuronal pathology of patients with Alzheimer's disease. To investigate how tau ...

journal_title：Neuroreport

authors： Takano M,Otani M,Sakai A,Kadoyama K,Matsuyama S,Matsumoto A,Takenokuchi M,Sumida M,Taniguchi T

更新日期：2009-12-09 00:00:00

abstract：:S100B is a calcium binding protein from astrocytes that regulates protein phosphorylation by binding to substrates and protein kinases. S100B might also regulate protein phosphatases and this was investigated for protein phosphatase 2B (calcineurin). The results indicate that S100B (5-10 microM) increased the activity...

journal_title：Neuroreport

authors： Leal RB,Frizzo JK,Tramontina F,Fieuw-Makaroff S,Bobrovskaya L,Dunkley PR,Gonçalves CA

更新日期：2004-02-09 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：:In this study, we have identified novel splice variants of the Na+ channel alpha subunit mRNA from cultured rat astrocytes and neuroblastoma cells. These splice variants are characterized by premature truncation or deletion of a segment in the third domain of the Na+ channel alpha subunit. The expression of three spli...

journal_title：Neuroreport

authors： Oh Y,Waxman SG

更新日期：1998-05-11 00:00:00

abstract：:Neuroimaging evidence suggests that human Brodmann area 5 (BA5) within the superior parietal lobule contributes to movement planning. However, a causal role for the contribution of BA5 to preparatory processes has yet to be reported. We used paired-pulse transcranial magnetic stimulation to investigate the influence o...

journal_title：Neuroreport

authors： Mackenzie TN,Bailey AZ,Mi PY,Tsang P,Jones CB,Nelson AJ

更新日期：2016-09-28 00:00:00

abstract：:Dysfunctional glutamate neurotransmission has been implicated in the pathophysiology of schizophrenia. Abnormal expressions in schizophrenia of ionotropic glutamate receptors (iGluRs) and the proteins that regulate their trafficking have been found to be region and subunit specific in brain, suggesting that abnormal t...

journal_title：Neuroreport

authors： Tucholski J,Simmons MS,Pinner AL,McMillan LD,Haroutunian V,Meador-Woodruff JH

更新日期：2013-08-21 00:00:00