Olfactory experience modulates Bcl-2 expression in the developing olfactory bulb.

abstract：:The glomerular layer of the olfactory bulb contains a substantial population of dopaminergic neurons. We determined the quantity and location of D1 and D2 dopamine receptors which are the presumed targets of these neurons. Binding of the D1 selective ligand [3H]SCH23390 was slightly above background and was distribute...

journal_title：Neuroreport

authors： Nickell WT,Norman AB,Wyatt LM,Shipley MT

更新日期：1991-01-01 00:00:00

abstract：:The present study was based on earlier findings that the observation of a coherently moving long bar induced gamma-band activity in humans. The power in the EEG-gamma-band was reduced during the presentation of two incoherently moving short bars. The present study demonstrates the replicability of this cortical activi...

journal_title：Neuroreport

authors： Müller MM,Junghöfer M,Elbert T,Rochstroh B

更新日期：1997-07-28 00:00:00

abstract：:We tested the hypothesis that in a cluttered visual scene, the magnocellular (M) pathway is crucial for focusing attention serially on the objects in the field. Since developmental dyslexia is commonly associated with an M pathway deficit, we compared reading impaired children and age-matched normal readers in a searc...

journal_title：Neuroreport

authors： Vidyasagar TR,Pammer K

更新日期：1999-04-26 00:00:00

abstract：:In this study it was shown that in adults, the frequency characteristics of EEG preceding stimuli that were followed by incorrect responses were different from the characteristics of EEG preceding stimuli that were followed by correct responses. In the recording during three different tasks that explore different neur...

journal_title：Neuroreport

authors： Fernández T,Harmony T,Silva-Pereyra J,Fernández-Bouzas A,Gersenowies J,Galán L,Carbonell F,Marosi E,Otero G,Valdés SI

更新日期：2000-08-21 00:00:00

abstract：:NMR signal intensities in five regions of the midsagittal corpus callosum were measured in autism patients and normal controls. An age-related increase in signal was observed in the anterior regions in both groups. No significant differences in intensity were detected between the groups. The finding of normal myelinat...

journal_title：Neuroreport

authors： Belmonte M,Egaas B,Townsend J,Courchesne E

更新日期：1995-06-19 00:00:00

abstract：:Amyotrophic lateral sclerosis is an incurable disease in which cerebral and spinal motoneurons degenerate, causing paralysis and death within 2-5 years. One of the pathogenic factors of motoneuron death is a chronic excess of glutamate, which exceeds its removal by astrocytes, i.e. excitotoxicity. Extra glutamate upta...

journal_title：Neuroreport

authors： Wisman LA,van Muiswinkel FL,de Graan PN,Hol EM,Bär PR

更新日期：2003-10-27 00:00:00

abstract：:The effects of interleukin-1beta in the paraventricular nucleus or caudal arcuate nucleus on hypertensive and tachycardiac responses induced by excitation of the central amygdaloid nucleus were studied. We observed that microinjection of sodium glutamate into central amygdaloid nucleus resulted in hypertension and tac...

journal_title：Neuroreport

authors： Lu Y,Chen W,Zou CJ

更新日期：2002-03-25 00:00:00

abstract：:Numerous reports have shown that cyclin-dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, critically contributes to the induction and maintenance of chronic pain induced by peripheral inflammation and nerve injury. Recent evidence has also suggested the critical role of an epigenetic mechanism in ...

journal_title：Neuroreport

authors： Li K,Zhao GQ,Li LY,Wu GZ,Cui SS

更新日期：2014-10-01 00:00:00

abstract：:We have previously reported that the developmental exposure of rats to altered gravity (1.65 g) from gestational day 8 to postnatal day 21 impacts motor functions and cerebellar structure. The present study examined whether the decrease in cerebellar mass accompanied by impaired performance on a rotorod in hypergravit...

journal_title：Neuroreport

authors： Sajdel-Sulkowska EM,Nguon K,Sulkowski ZL,Rosen GD,Baxter MG

更新日期：2005-12-19 00:00:00

abstract：:Event-related potentials(ERPs) were measured while subjects were constructing mental images of a letter of the alphabet. Following presentation of an uppercase letter, subjects were asked to form a mental image of the same letter in lower case, and determine whether or not it had an ascending or descending stroke (asc...

journal_title：Neuroreport

authors： Yamamoto S,Mukai H

更新日期：1998-10-26 00:00:00

abstract：:Deficiencies of Ca2+ homeostasis are proposed to play an important role in neuronal ageing and/or neurodegeneration. The aim of this study was to investigate, in a defined neuronal population, primary cerebellar granule neuron culture, the time-dependent changes in Ca2+ homeostasis and compare them with data obtained ...

journal_title：Neuroreport

authors： Toescu EC,Verkhratsky A

更新日期：2000-11-27 00:00:00

abstract：:This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice ...

journal_title：Neuroreport

authors： Matsumoto M,Nakagawa T,Higashi T,Kim TS,Kojima K,Kita T,Sakamoto T,Ito J

更新日期：2005-05-31 00:00:00

abstract：:We investigated the influence of gravity on the maturation of electrical properties of lumbar motoneurons and the development of their inputs from ventral descending pathways, which are important for the control of posture and locomotion. Using electrophysiological approaches in the in vitro brain stem-spinal cord pre...

journal_title：Neuroreport

authors： Brocard F,Clarac F,Vinay L

更新日期：2003-09-15 00:00:00

abstract：:Three adult Japanese monkeys (M. fuscata: body weights 4.5-8.5 kg) were trained to walk quadrupedally on a surface of a moving treadmill (walking length and width: 150 cm and 60 cm, treadmill speed: 0.4-1.7 m s-1. At any different constant treadmill velocity, the monkeys exhibited a diagonal pattern of locomotor movem...

journal_title：Neuroreport

authors： Mori S,Miyashita E,Nakajima K,Asanome M

更新日期：1996-10-02 00:00:00

abstract：:Pulmonary slowly adapting receptors (SARs) and rapidly adapting receptors (RARs) are important components of various respiratory reflexes. In anesthetized, paralyzed and artificially ventilated rats, we found an inhibitory linkage from the former to the latter system at the level of their second-order relay neurons (P...

journal_title：Neuroreport

authors： Ezure K,Tanaka I

更新日期：2000-06-05 00:00:00

abstract：:Vectors based on lentiviruses are opening up new approaches for the treatment of neurodegenerative diseases. Currently, the equine infectious anaemia virus (EIAV) vector is one of the most attractive gene delivery systems with respect to neuronal tropism. The aim was to validate EIAV-lentiviral vectors as a gene deliv...

journal_title：Neuroreport

authors： Azzouz M,Ralph S,Wong LF,Day D,Askham Z,Barber RD,Mitrophanous KA,Kingsman SM,Mazarakis ND

更新日期：2004-04-29 00:00:00

abstract：:Dopaminergic neurotransmission is thought to be involved in reward-related incentive learning and addictive behaviour. Amphetamine will alter glycogen synthase kinase-3β (GSK-3β) activity by increasing dopamine transporter efflux rates. We investigated the hypothesis that Wnt signalling will be altered in rat nucleus ...

journal_title：Neuroreport

authors： MacLeod RJ,Moores ME,Beninger RJ

更新日期：2012-10-03 00:00:00

abstract：:A tritiated specific and highly potent 5-HT4 antagonist: [3H]-GR113808 was used to label specific binding sites in human brain and for comparison in guinea-pig brain. [3H]-GR113808 association and dissociation were rapid, the binding was saturable and displaced by various serotoninergic agents with an affinity corresp...

journal_title：Neuroreport

authors： Waeber C,Sebben M,Grossman C,Javoy-Agid F,Bockaert J,Dumuis A

更新日期：1993-09-10 00:00:00

abstract：:MicroRNAs (miRNAs) play important roles in drug tolerance and regulating pain. The purpose of the present study is to explore the regulatory mechanism of miR-124-3p on dezocine tolerance against pain in a rat model. The expression of miR-124-3p and TRAF6 in spinal cord of rats was detected by quantitative reverse-tran...

journal_title：Neuroreport

authors： Huo Y,Zhang K,Zhang T,Han Y,Hu Z

更新日期：2021-01-06 00:00:00

abstract：:Prior research with rodent models, performed predominantly in males, has demonstrated a significant association between focal neocortical malformations (e.g. ectopias and microgyria) and rate-specific auditory processing deficits. In the current study and consistent with prior findings, we report that ectopic male BXS...

journal_title：Neuroreport

authors： Peiffer AM,Rosen GD,Fitch RH

更新日期：2002-12-03 00:00:00

abstract：:Recent studies of electroencephalogram event-related potentials reported aberrant feedback-related negativity (FRN) in neurological and psychiatric diseases, such as alcoholism and attention-deficit hyperactivity disorder. These diseases are characterized by high impulsivity. We investigated the relationship between F...

journal_title：Neuroreport

authors： Onoda K,Abe S,Yamaguchi S

更新日期：2010-07-14 00:00:00

abstract：:The effect of temporal interference of physiological signals on time-lag effective connectivity, derived from a functional network connectivity tool box (FNC), was examined by a blood-oxygen-level-dependent functional MRI study of action. The known effect of physiological signals on time-lag FNC was verified by (a) co...

journal_title：Neuroreport

authors： Huang JM,Cheng CM,Chou CC,Chen YC,Hsu PY,Yeh TC

更新日期：2013-01-09 00:00:00

abstract：:Kisspeptin is distributed not only in brain areas for regulating reproduction but also in nuclei involved in feeding control. Whether kisspeptin alters food intake is unknown in mice. We examined how kisspeptin-10 influences feeding after intracerebroventricular injection in mice using automated monitoring. Kisspeptin...

journal_title：Neuroreport

authors： Stengel A,Wang L,Goebel-Stengel M,Taché Y

更新日期：2011-03-30 00:00:00

abstract：:N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...

journal_title：Neuroreport

authors： Montag-Sallaz M,Montag D,Schachner M

更新日期：2003-07-18 00:00:00

abstract：:Neuroimaging evidence suggests that human Brodmann area 5 (BA5) within the superior parietal lobule contributes to movement planning. However, a causal role for the contribution of BA5 to preparatory processes has yet to be reported. We used paired-pulse transcranial magnetic stimulation to investigate the influence o...

journal_title：Neuroreport

authors： Mackenzie TN,Bailey AZ,Mi PY,Tsang P,Jones CB,Nelson AJ

更新日期：2016-09-28 00:00:00

abstract：:Cultured and transplanted adrenal medullary cells respond to ciliary neurotrophic factor (CNTF) with neurite formation and improved cell survival although the presence of the CNTF receptor-alpha (CNTFRalpha) has been unclear. This study show that CNTFRalpha mRNA was expressed in the postnatal day 1 as well as in the a...

journal_title：Neuroreport

authors： Förander P,Brené S,Strömberg I

更新日期：2000-02-28 00:00:00

abstract：:Alopecia areata (AA) is a dermatosis involving the sudden occurrence of bald patches on the scalp. Although the aetiology is unknown, experimental data indicate that cutaneous microcirculation plays an important role. The skin is richly innervated by neuropeptidergic sensory nerves that help regulate microvascular cir...

journal_title：Neuroreport

authors： Rossi R,Del Bianco E,Isolani D,Baccari MC,Cappugi P

更新日期：1997-03-24 00:00:00

abstract：:In marked contrast to several other species, including rats and humans, leptin gene expression is undetectable in mouse brain. This unexpected finding may reflect unique energy regulation pathways in the mouse. We investigated possible mechanisms by which leptin (ob) gene expression is suppressed in mouse brain: (a) t...

journal_title：Neuroreport

authors： Brown RE,Wilkinson DA,Wilkinson PM,Imran SA,Wilkinson M

更新日期：2012-10-24 00:00:00

abstract：:The effects of histamine on N-methyl-d-aspartate (NMDA) receptor-mediated ion current in cultured rat cortical neurones have been investigated by superfusion of voltage-clamped (-80 mV) cells with 100 mM NMDA and with various concentrations of histamine. In a subpopulation of the neurones tested (30/53), histamine (10...

journal_title：Neuroreport

authors： Zwart R,Blank T,Spiess J

更新日期：1996-09-02 00:00:00

abstract：:The presence and regulation of pituitary adenylate cyclase activating peptide (PACAP) was investigated in the adult rat superior cervical ganglion. Double-labelling immunofluorescence using specific antibodies against PACAP and vasoactive intestinal peptide (VIP) revealed a dense innervation of postganglionic sympathe...

journal_title：Neuroreport

authors： Klimaschewski L,Hauser C,Heym C

更新日期：1996-11-04 00:00:00