PACAP immunoreactivity in the rat superior cervical ganglion in comparison to VIP.

Abstract:

:The presence and regulation of pituitary adenylate cyclase activating peptide (PACAP) was investigated in the adult rat superior cervical ganglion. Double-labelling immunofluorescence using specific antibodies against PACAP and vasoactive intestinal peptide (VIP) revealed a dense innervation of postganglionic sympathetic neurones by PACAP-immunoreactive but VIP-negative nerve endings that mainly were of preganglionic origin since they disappeared after transection of the cervical sympathetic trunk. Since PACAP regulates transmitter synthesis and release in sympathetic neurones in vitro, this finding provides a morphological correlate for modulatory effects of PACAP in vivo. Few neurones contained PACAP under normal conditions. However, the number of PACAP-positive neurones increased in response to axotomy of the postganglionic nerves. Many of the newly PACAP-positive neurones also contained VIP, suggesting that both peptides are regulated by similar mechanisms.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Klimaschewski L,Hauser C,Heym C

doi

10.1097/00001756-199611040-00078

subject

Has Abstract

pub_date

1996-11-04 00:00:00

pages

2797-801

issue

15-17

eissn

0959-4965

issn

1473-558X

journal_volume

7

pub_type

杂志文章
  • Expression of activin receptors type I and II only partially overlaps in the nervous system.

    abstract::In situ hybridization was used to localize mRNA encoding two cooperative serine/threonine kinase receptors. Activin receptor IIA mRNA in the adult rat brain is highly expressed in the dentate gyrus, in the pyramidal neurones of CA3 and CA1, in the entorhinal cortex, in the cortical amygdaloid nucleus and in the amygda...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:

    authors: Bengtsson H,Söderström S,Ebendal T

    更新日期:1995-12-29 00:00:00

  • Inhibition of microRNA-429 attenuates oxygen-glucose deprivation/reoxygenation-induced neuronal injury by promoting expression of GATA-binding protein 4.

    abstract::MicroRNAs (miRNAs) have been documented as critical regulators in ischemia/reperfusion-induced neuronal death. A better understanding of miRNA-mediated molecular mechanisms in ischemia/reperfusion-induced neuronal death may provide therapeutic targets for cerebral ischemia/reperfusion injury. A growing body of evidenc...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001023

    authors: Xiao J,Kong R,Hu J

    更新日期:2018-06-13 00:00:00

  • Membrane fatty acid composition shows delta-6-desaturase abnormalities in Alzheimer's disease.

    abstract::Brain membrane phospholipid fatty acid composition is investigated in Alzheimer's disease using fresh pathologically proven autopsy material. The most striking abnormalities in Alzheimer brains compared to age-matched controls are found in the n - 6 line of polyunsaturated fatty acids (PUFA) showing an elevation of 18...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199010000-00018

    authors: Nakada T,Kwee IL,Ellis WG

    更新日期:1990-10-01 00:00:00

  • Retinal ganglion cell axons regenerate in the presence of intact sensory fibres.

    abstract::A novel allograft paradigm was used to test whether adult mammalian central axons regenerate within a peripheral nerve environment containing intact sensory axons. Retinal ganglion cell axon regeneration was compared following anastomosis of dorsal root ganglia grafts or conventional peripheral nerve grafts to the adu...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000195668.07467.a8

    authors: King C,Bartlett C,Sauvé Y,Lund R,Dunlop S,Beazley L

    更新日期:2006-02-06 00:00:00

  • Odors increase Fos in olfactory bulb neurons including dopaminergic cells.

    abstract::Neuronal activity may lead to long lasting changes in cell phenotype through induction of genes such as c-fos which encode transcriptional regulatory factors. Odor-activated olfactory bulb cells exhibit increases in c-fos mRNA expression. The present study examined whether odor stimulation of awake rats also leads to ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199511000-00012

    authors: Guthrie KM,Gall CM

    更新日期:1995-11-13 00:00:00

  • Carrageenan oedema and spinal Fos-LI neurones are reduced by piroxicam in the rat.

    abstract::Intraplantar carrageenan induced a peripheral oedema and c-Fos like immunoreactivity (Fos-LI) in L4-L5 segments in the dorsal horn (DH) of the rat spinal cord. The total number of carrageenan evoked Fos-LI neurones was 153 +/- 10 per section, with a predominant localization in the superficial and deep laminae of the D...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199507100-00006

    authors: Buritova J,Honoré P,Chapman V,Besson JM

    更新日期:1995-07-10 00:00:00

  • Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory.

    abstract::The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed befo...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/WNR.0b013e3282f2adfd

    authors: Ohn SH,Park CI,Yoo WK,Ko MH,Choi KP,Kim GM,Lee YT,Kim YH

    更新日期:2008-01-08 00:00:00

  • Receptor autoradiography with 11C and [3H]-labelled ligands visualized by imaging plates.

    abstract::The distribution of histamine H1, H3, dopamine D1 and D2 receptors in the brain was studied by receptor autoradiography using a high-sensitivity and high-resolution imaging plate system. [3H]Pyrilamine, [3H](R)alpha-methyl-histamine, [11C]SCH23390, and [11C]N-methylspiperone (or [11C]YM-09151-2) were used as ligands t...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199211000-00003

    authors: Yanai K,Ryu JH,Watanabe T,Iwata R,Ido T

    更新日期:1992-11-01 00:00:00

  • Stereoscopic depth perception in the owl.

    abstract::It is unclear whether the neural algorithm that underlies stereoscopic vision in birds incorporates both low level (camouflage breaking) and high level (depth ordering) comparisons of information available to each of the eyes. Both visual functions were successfully tested by examining transitive inference performance...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199804200-00050

    authors: van der Willigen RF,Frost BJ,Wagner H

    更新日期:1998-04-20 00:00:00

  • Inducible microglial nitric oxide synthase: a large membrane pool.

    abstract::Microglia are the only immunocompetent cells resident in the central nervous system which are capable of protecting the brain from infection and tumors. These resident macrophages possess a vast array of mechanisms for the destruction of bacteria and tumor cells. One of these mechanisms involves the generation of nitr...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199404000-00031

    authors: Wood PL,Choksi S,Bocchini V

    更新日期:1994-04-14 00:00:00

  • Successful outcomes of cochlear implantation in long-term unilateral deafness: brain plasticity?

    abstract::To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283642a93

    authors: Távora-Vieira D,Boisvert I,McMahon CM,Maric V,Rajan GP

    更新日期:2013-09-11 00:00:00

  • Corticospinal projections from mesial frontal and cingulate areas in the monkey.

    abstract::We injected neural tracers into the lateral funiculus of the spinal cord in order to relate the sites of origin of the spinal projections from the mesial cortical surface with the cytoarchitectonic organization of this region. We found a close correlation between the origin sites and density of corticospinal projectio...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199412000-00035

    authors: Luppino G,Matelli M,Camarda R,Rizzolatti G

    更新日期:1994-12-20 00:00:00

  • Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders.

    abstract::Chimeric mice stably reconstituted with bone marrow cells represent a good model for analysis of the mechanism of bone marrow cell infiltration in the brain. However, in preparing chimeric mice, irradiation of the recipient mice is necessary to kill their own bone marrow before transplantation, which induces gliosis a...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200303240-00021

    authors: Furuya T,Tanaka R,Urabe T,Hayakawa J,Migita M,Shimada T,Mizuno Y,Mochizuki H

    更新日期:2003-03-24 00:00:00

  • Neuroanatomic correlates of autism and stereotypy in children with Down syndrome.

    abstract::We conducted semiautomated, atlas-based analyses of regional brain volume changes on MRIs of children and adolescents with Down syndrome (DS) (N=15), DS with comorbid autism spectrum disorder (ASD) (N=15), and age-matched or sex-matched typically developing controls (N=22). Selective volumetric changes were correlated...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3282faa8d8

    authors: Carter JC,Capone GT,Kaufmann WE

    更新日期:2008-04-16 00:00:00

  • Sensory-specific satiety-related olfactory activation of the human orbitofrontal cortex.

    abstract::When a food is eaten to satiety, its reward value decreases. This decrease is usually greater for the food eaten to satiety than for other foods, an effect termed sensory-specific satiety. In an fMRI investigation it was shown that for a region of the orbitofrontal cortex the activation produced by the odour of the fo...

    journal_title:Neuroreport

    pub_type: 更正并重新发布的文章,杂志文章

    doi:10.1097/00001756-200003200-00046

    authors: O'Doherty J,Rolls ET,Francis S,Bowtell R,McGlone F,Kobal G,Renner B,Ahne G

    更新日期:2000-03-20 00:00:00

  • Event-related potentials in an emotional go/no-go task and remission of geriatric depression.

    abstract::Anterior cingulate integrity may be required for antidepressant response. To assess anterior cingulate processes related to treatment response, we studied error-related negativity and error positivity produced during an emotional go/no-go challenge, a task activating the rostral anterior cingulate. Twelve elderly pati...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e328013ceda

    authors: Alexopoulos GS,Murphy CF,Gunning-Dixon FM,Kalayam B,Katz R,Kanellopoulos D,Etwaroo GR,Klimstra S,Foxe JJ

    更新日期:2007-02-12 00:00:00

  • Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs.

    abstract::Transgenic mouse strains were generated that overexpress human APP or clinical mutants of APP. All transgenic mouse strains that over-express APP displayed essentially the same phenotype of disturbed behaviour, differential glutamatergic responses, deficits in maintenance of long-term potentiation and premature death,...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199811160-00004

    authors: Moechars D,Gilis M,Kuipéri C,Laenen I,Van Leuven F

    更新日期:1998-11-16 00:00:00

  • An ignoring task improves validity of cortical evoked response audiometry.

    abstract::This study examined the basis for introducing an ignoring task during cortical evoked response audiometry (CERA) using the N1-P2 response. Healthy hearing participants were assigned to two groups with and without an ignoring task (ignoring and listening groups) during CERA whose outcomes were compared with the pure-to...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32833b502a

    authors: Ikeda K,Hayashi A,Matsuda O,Sekiguchi T

    更新日期:2010-07-14 00:00:00

  • Autoantigen Ku in the brain. Developmentally regulated expression and subcellular localization.

    abstract::A double-stranded DNA end-binding factor with high levels of expression in brain and testis of adult mice was identified as the Ku protein, earlier described as an autoantigen in connective tissue diseases and found to be essential for recombination of the immunoglobulin genes and DNA repair. High Ku levels were found...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199806220-00044

    authors: Bakalkin G,Yakovleva T,Hurd YL,Nussenzweig A,Li GC,Terenius L

    更新日期:1998-06-22 00:00:00

  • PSD95 protein level rises in murine somatosensory cortex after sensory training.

    abstract::Proteins of the postsynaptic density are implicated in mechanisms of synaptic plasticity. We examined involvement of PSD95 and alphaCaMkII in learning-dependent plastic changes of representational maps in somatosensory cortex of mice. The barrel cortex of mice was examined following a 3 day long classical conditioning...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200109170-00030

    authors: Skibinska A,Lech M,Kossut M

    更新日期:2001-09-17 00:00:00

  • Estrogen effects on arcuate neurons in rat. An in situ electrophysiological study.

    abstract::In acute experiments, the effects of i.p. 17beta-estradiol on the activity of arcuate neurons were studied in ovariectomized rats. 17Beta-estradiol (100 microg/100g, i.p.) increased the spontaneous activity of the observed arcuate neurons with a latency of 20-25 min. In some neurons spontaneous activity could be influ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199911260-00034

    authors: Kis Z,Horváth S,Hoyk Z,Toldi J,Párducz A

    更新日期:1999-11-26 00:00:00

  • Abnormal spontaneous brain activity in patients with generalized anxiety disorder revealed by resting-state functional MRI.

    abstract::This study aimed to examine the spontaneous hemodynamic fluctuations and the dysfunctional brain regions in patients with generalized anxiety disorder (GAD) using resting-state functional MRI. Previous studies have demonstrated some neural networks that are different in this patient group compared with healthy control...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000982

    authors: Li C,Su S,Wu H,Zhu Y

    更新日期:2018-03-21 00:00:00

  • fMRI of human somatosensory and cingulate cortex during painful electrical nerve stimulation.

    abstract::Functional MRI (fMRI) can detect changes from resting levels of blood flow and oxygenation during task performance (i.e. activation). We used a simple electrical nerve stimulation technique together with fMRI to study pain process in the human cortex. Images of the primary somatosensory (SI) and cingulate cortex (Cg) ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:

    authors: Davis KD,Wood ML,Crawley AP,Mikulis DJ

    更新日期:1995-12-29 00:00:00

  • Spontaneous axonal regeneration after optic nerve injury in adult rat.

    abstract::Optic nerves of adult rats were crushed 2 mm behind the eye to examine the ability of retinal ganglion cells (RGCs) to regenerate their axons. Some animals were treated with the immunophilin ligands FK 506 or GPI 1046 for up to 4 weeks. After 10 days to 16 months, regenerating RGC axons were visualized using anterogra...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199912160-00042

    authors: Campbell G,Holt JK,Shotton HR,Anderson PN,Bavetta S,Lieberman AR

    更新日期:1999-12-16 00:00:00

  • Hippocampal, parahippocampal and occipital-temporal contributions to associative and item recognition memory: an fMRI study.

    abstract::The temporal lobe regions involved in memory retrieval were examined using fMRI. During an associative recognition test, participants made memory judgments about the study color of previously presented drawings of objects, and during item recognition tests they made old/new judgments about previously studied objects o...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200102120-00035

    authors: Yonelinas AP,Hopfinger JB,Buonocore MH,Kroll NE,Baynes K

    更新日期:2001-02-12 00:00:00

  • Increases in K+ conductance and Ca2+ influx under high glucose with suppressed Na+/K+-pump activity in rat myelinated nerve fibers.

    abstract::To test the combined effect of high glucose and decreased Na+/K+-pump activity, a condition which closely mimics the diabetic state, on nerve ionic currents, changes in action potential and membrane current induced by high glucose in the presence of ouabain were investigated using voltage clamp analysis in rat single ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200008030-00040

    authors: Takigawa T,Yasuda H,Terada M,Maeda K,Haneda M,Kashiwagi A,Kitasato H,Kikkawa R

    更新日期:2000-08-03 00:00:00

  • Maternal behavior: activation of the central oxytocin receptor system in parturient rats?

    abstract::Parturition plays a critical role in the full expression of maternal behavior in postpartum females, yet the precise mechanism remains unclear. Here we examined the role of parturition in the activation of Fos and FosB in the central oxytocin receptor (OTR) system in rats. Although expression of FosB, not Fos, was see...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200308060-00007

    authors: Lin SH,Kiyohara T,Sun B

    更新日期:2003-08-06 00:00:00

  • Detection of dopaminergic cell loss and neural transplantation using pharmacological MRI, PET and behavioral assessment.

    abstract::We demonstrate the use of magnetic resonance imaging (MRI) for detection of neurotransmitter stimulation using the dopamine transporter ligands amphetamine and CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane) as pharmacological challenges. We demonstrate that the unilateral loss of a hemodynamic response to eith...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199909290-00001

    authors: Chen YI,Brownell AL,Galpern W,Isacson O,Bogdanov M,Beal MF,Livni E,Rosen BR,Jenkins BG

    更新日期:1999-09-29 00:00:00

  • Neuronal response specificity as a marker of reading proficiency: two-fold nature of the N170 revealed after massive repetition.

    abstract::Reading demands precise and efficient letter and word processing. This event-related potentials (ERP) study utilized massive repetition of visually presented single letters to trigger neuronal adaptation. Our aim was to explore whether the adaptation pattern of the N170 ERP component, serving as an indicator of neuron...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32835d20b1

    authors: Korinth SP,Sommer W,Breznitz Z

    更新日期:2013-01-23 00:00:00

  • High-frequency SEP components generated in the somatosensory cortex of the monkey.

    abstract::To investigate the origin of high-frequency somatosensory evoked potential (SEP) components, we recorded median nerve SEPs from the scalp and the depth in six monkeys. Laminar field potentials were analyzed in area 3b (N10; corresponding to human N20) and area 1 (P12; corresponding to human P25). After digital filteri...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200008210-00042

    authors: Shimazu H,Kaji R,Tsujimoto T,Kohara N,Ikeda A,Kimura J,Shibasaki H

    更新日期:2000-08-21 00:00:00