Neuronal response specificity as a marker of reading proficiency: two-fold nature of the N170 revealed after massive repetition.

abstract：:We recorded event-related potentials (ERPs) in 2-month-old infants in two different states of alertness: awake and asleep. Syllables varying in vowel duration (long vs short) were presented in an oddball paradigm, known to elicit a mismatch brain response. ERPs of both groups showed a mismatch response reflected in a ...

journal_title：Neuroreport

authors： Friederici AD,Friedrich M,Weber C

更新日期：2002-07-19 00:00:00

abstract：:There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to the level of sentence syntax. Although birdsong can indeed have a complex structure, it lacks the combinatori...

journal_title：Neuroreport

authors： Beckers GJ,Bolhuis JJ,Okanoya K,Berwick RC

更新日期：2012-02-15 00:00:00

abstract：:The aim of this study was to investigate whether frontal lobe damage affects thalamic volume in humans. Ipsilateral and contralateral thalamic areas were measured in 0.5T T1-weighted sagittal magnetic resonance images in 12 patients, first at the time of their surgery for relief of a unilateral frontal lobe brain tumo...

journal_title：Neuroreport

authors： Hulshoff Pol HE,van der Flier WM,Schnack HG,Tulleken CA,Ramos LM,van Ree JM,Kahn RS

更新日期：2000-09-11 00:00:00

abstract：:Evidences in the central nervous system are in favor that adenosine under basal conditions is released by a direct excitation-secretion modality. However, till now, there is no direct evidence that adenosine is contained in synaptic vesicles. Eight synaptic vesicle fractions were recovered on a discontinuous sucrose g...

journal_title：Neuroreport

authors： Corti F,Cellai L,Melani A,Donati C,Bruni P,Pedata F

更新日期：2013-12-04 00:00:00

abstract：:A synchronizing volley of excitation was delivered to cells from the primary visual cortex of the anaesthetized cat by an electrical pulse stimulation of the optic radiations. In intracellular records, this resulted in an initial, fast depolarization of the membrane potential followed by a longer lasting (266 ms) hype...

journal_title：Neuroreport

authors： Ahmed B

更新日期：2000-04-27 00:00:00

abstract：:Metabolic hypofunction is a common finding in a number of neurodegenerative diseases, including Alzheimer's disease (AD). The strong linkage between the amyloid precursor protein (APP) and AD led us to examine whether over-expression of this protein in CNS-type cells had an effect on mitochondria. We found abnormal mo...

journal_title：Neuroreport

authors： Grant SM,Shankar SL,Chalmers-Redman RM,Tatton WG,Szyf M,Cuello AC

更新日期：1999-01-18 00:00:00

abstract：:α-Gustducin (Gα-gust) is the α subunit of the heterotrimeric G-protein complex specific for taste receptor cells of the tongue. However, it has been shown to be present in ectopic regions, such as airways and digestive tract. Recently, Gα-gust was found within neurons in various regions of the mouse brain. In this stu...

journal_title：Neuroreport

authors： Son MJ,Hu YJ,Kim SA,Chun MH,Kim IB,Kim MS

更新日期：2011-02-16 00:00:00

abstract：:Prepulse inhibition (PPI) of the acoustic startle reflex is a measure of sensorimotor gating which occurs in both rodents and humans. PPI is deficient in severe neuropsychiatric disorders such as schizophrenia. We investigated PPI in 10 adult monkeys (Cebus apella). Stimuli were 115 dB white noise startle pulses, eith...

journal_title：Neuroreport

authors： Linn GS,Javitt DC

更新日期：2001-01-22 00:00:00

abstract：:Antisera were produced against synthetic peptides predicted from the recent cloning of a delta opioid receptor, DOR-1. Confocal microscopic examination of immunostained spinal cord sections revealed that DOR-1 immunoreactive (-ir) nerve fibers and terminals form a moderately dense plexus within the superficial dorsal ...

journal_title：Neuroreport

authors： Dado RJ,Law PY,Loh HH,Elde R

更新日期：1993-12-13 00:00:00

abstract：OBJECTIVE:The traditional Chinese medicine, Dendrobium nobile Lindl. polysaccharides (DNLP), reportedly has neuroprotective effects. However, its effects following ischemic stroke remain unclear. This study aimed to explore the role and mechanism of DNLP in experimental models of inflammation and apoptosis. METHODS:In...

journal_title：Neuroreport

authors： Liu J,Han Y,Zhu T,Yang Q,Wang H,Zhang H

更新日期：2020-12-14 00:00:00

abstract：:We investigated the effect of the muscarinic acetylcholine receptor (mAChR) antagonist scopolamine on eyeblink conditioning in glutamate receptor subunit 62 null mice, which have severe impairments in cerebellar long-term depression (LTD). Mice were injected intraperitoneally with scopolamine (0.5 mg/kg) or saline, an...

journal_title：Neuroreport

authors： Takatsuki K,Kawahara S,Mori H,Mishina M,Kirino Y

更新日期：2002-01-21 00:00:00

abstract：:Regulation of CNTF mRNA was investigated in primary cortical astrocytes cultured from newborn rats and in C6 glioma cells. Northern blot analysis indicated that semi-confluent astrocyte cell cultures. CNTF added to confluent astrocyte cultures down-regulated CNTF message in a dose-dependent fashion. In contrast, when ...

journal_title：Neuroreport

authors： Meyer V,Unsicker K

更新日期：1994-10-03 00:00:00

abstract：:24S-hydroxycholesterol, the primary oxidation product of cholesterol in the brain, plays a key role in cholesterol elimination and homeostasis. While the concentration of this neurotoxic oxysterol decreases with age, 24S-hydroxycholesterol is elevated in Alzheimer's disease. In this study, we examined the effects of 2...

journal_title：Neuroreport

authors： Alexandrov P,Cui JG,Zhao Y,Lukiw WJ

更新日期：2005-06-21 00:00:00

abstract：:Prepulse inhibition (PPI) and reactivity of the acoustic startle response are widely used biobehavioral markers in psychopathology research. Previous studies have demonstrated that PPI and startle reactivity exhibit substantial within-site stability; however, between-site stability has not been established. In two sep...

journal_title：Neuroreport

authors： Cadenhead KS,Addington J,Cannon TD,Cornblatt BA,de la Fuente-Sandoval C,Mathalon DH,Perkins DO,Seidman LJ,Tsuang M,Walker EF,Woods SW,Bachman P,Belger A,Carrión RE,Donkers FC,Duncan E,Johannesen J,León-Ortiz P,Light G

更新日期：2013-08-07 00:00:00

abstract：:In this experiment, event-related potentials were used to examine whether the neural correlates of encoding processes predicting subsequent successful recall differed from those predicting successful source memory retrieval. During encoding, participants studied lists of words and were instructed to memorize each word...

journal_title：Neuroreport

authors： Angel L,Isingrini M,Bouazzaoui B,Fay S

更新日期：2013-03-06 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for serotonin type 6 receptors (5HT6). We tested the hypothesis that clinical response to clozapine in patients refractory to typical antipsychotic treatment is related to the genetic variant (C267T) of the 5HT6 receptors. Ninety-nine schizophreni...

journal_title：Neuroreport

authors： Yu YW,Tsai SJ,Lin CH,Hsu CP,Yang KH,Hong CJ

更新日期：1999-04-26 00:00:00

abstract：:The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestati...

journal_title：Neuroreport

authors： Belai A,Burnstock G

更新日期：2000-01-17 00:00:00

abstract：:Subcortical visual inputs to motion-selective cortex in primates survive after damage to the primary visual cortex (area 17/V1). Activation of human motion cortex was examined using scalp electrodes in a V1-damaged hemianope. Blind field motion-onset visual evoked potentials (VEPs) shared many of the characteristics a...

journal_title：Neuroreport

authors： Benson PJ,Guo K,Hardiman MJ

更新日期：1999-11-26 00:00:00

abstract：:4-Aminobenzovesamicol was used to test whether activation of protein kinase C protects the vesicular acetylcholine transporter from interaction with vesamicol-like drugs. The essentially irreversible vesamicol analog inhibits the release of newly synthesized [3H]acetylcholine from stimulated hippocampal slices. Prior ...

journal_title：Neuroreport

authors： Clarizia AD,Gomez MV,Romano-Silva MA,Parsons SM,Prado VF,Prado MA

更新日期：1999-09-09 00:00:00

abstract：:The serum-free mouse embryo (SFME) cell line, derived from 16-day-old mouse embryos in medium in which serum was replaced by growth factors and other supplements, has been cultured for more than 200 generations. SFME cells are nontumorigenic, lack gross chromosomal abnormalities, and display characteristics of CNS pro...

journal_title：Neuroreport

authors： Loo DT,Althoen MC,Cotman CW

更新日期：1994-08-15 00:00:00

abstract：:In situ hybridization has demonstrated mRNA for olfactory receptors (OR) in the axon terminals of olfactory receptor neurons. Neurons that express the same OR appear to send their axons to two stereotyped glomeruli in the olfactory bulb (OB). Based on these observations, we tested the feasibility of using RT-PCR to is...

journal_title：Neuroreport

authors： Singer MS,Hughes TE,Shepherd GM,Greer CA

更新日期：1998-11-16 00:00:00

abstract：:Extracellular recordings were used to determine the effects of cannabinoids on the activity of dopamine neurons within the ventral tegmental area (VTA) and substantia nigra pars compacta (SNC). Systemic administration of the natural psychoactive cannabinoid delta 9-tetrahydrocannabinol (delta 9-THC) and the synthetic ...

journal_title：Neuroreport

authors： French ED,Dillon K,Wu X

更新日期：1997-02-10 00:00:00

abstract：:Sensory funneling of liminal multiple-point air-puff stimulation on the skin was evaluated by measuring somatosensory evoked potentials (SEPs), reaction time (RT) and subjective detection threshold. Single-point air-puffs at the threshold intensity, and 2-point and 3-point air-puffs (10 mm apart) of the same intensity...

journal_title：Neuroreport

authors： Hashimoto I,Yoshikawa K,Kimura T

更新日期：1999-10-19 00:00:00

abstract：:Intrinsic circuitry in the barrel cortex has been shown to be readily modifiable in response to changes in the patterns of sensory input, even in adult animals. It is believed that sensory experience modifies synaptic circuits by imposing specific patterns of repetitive presynaptic and postsynaptic coactivity, i.e. by...

journal_title：Neuroreport

authors： Aroniadou-Anderjaska V,Keller A

更新日期：1995-11-27 00:00:00

abstract：:Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of cerebrovascular diseases. Using organ culture as a model for possible pathological changes we studied changes in ET(A) and ETB receptor function using a sensitive in vitro method. We observed an up-regulation of the ET(B) receptor and an ama...

journal_title：Neuroreport

authors： Hansen-Schwartz J,Edvinsson L

更新日期：2000-02-28 00:00:00

abstract：:Spinally administered adenosine reduces hypersensitivity in animals and humans with nerve injury, but also causes transient pain in humans and reduces tonic inhibition in spinal neurons. Nerve injury results in increased tonic spinal cord adenosine A1 receptor activation, consistent with a role for adenosine to genera...

journal_title：Neuroreport

authors： Martin TJ,Eisenach JC,Misler J,Childers SR

更新日期：2006-10-23 00:00:00

abstract：:Propofol is widely used for induction and maintenance of anaesthesia, which causes a rapid loss of consciousness. So far the mechanisms underlying the effect of propofol are still largely unknown. Here, we found that microinjection of propofol in the lateral hypothalamus caused a significant decrease in wakefulness an...

journal_title：Neuroreport

authors： Shi Y,Xiao D,Dai L,Si Y,Fang Q,Wei X

更新日期：2019-10-09 00:00:00

abstract：:Although citral, which is abundantly present in lemongrass, has various actions including antinociception, how citral affects synaptic transmission has not been examined as yet. Citral activates in heterologous cells transient receptor potential vanilloid-1, ankyrin-1, and melastatin-8 (TRPV1, TRPA1, and TRPM8, respec...

journal_title：Neuroreport

authors： Zhu L,Fujita T,Jiang CY,Kumamoto E

更新日期：2016-02-10 00:00:00

abstract：:Bone marrow stromal cells are multipotent stem cells that have the potential to differentiate into bone, cartilage, fat and muscle. Recently, bone marrow stromal cells have been shown to have the capacity to differentiate into neurons under specific experimental conditions, using chemical factors. We now describe how ...

journal_title：Neuroreport

authors： Zurita M,Vaquero J,Oya S,Miguel M

更新日期：2005-04-04 00:00:00

abstract：:Sciatic nerve resection leaving a 15 mm gap could not be repaired by bridging the stumps with a silicone tube prefilled with a laminin gel. However, when purified olfactory ensheathing cells (EC) were added to the gel filling the tube, successful axonal regeneration was observed in 50% of rats. With 12 mm gaps, regene...

journal_title：Neuroreport

authors： Verdú E,Navarro X,Gudiño-Cabrera G,Rodríguez FJ,Ceballos D,Valero A,Nieto-Sampedro M

更新日期：1999-04-06 00:00:00