Cortical evoked potentials due to motion contrast in the blind hemifield.

abstract：:The aim was to study the effects of an NMDA receptor antagonist on caspase-3 activation and DNA fragmentation after hypoxia-ischemia (HI) in 7-day-old rats. Animals were treated with vehicle or MK-801 (0.5 mg/kg) directly after HI and sacrificed 8, 24 or 72h later. MK-801 reduced injury (by 53%), cells positive for ac...

journal_title：Neuroreport

authors： Puka-Sundvall M,Hallin U,Zhu C,Wang X,Karlsson JO,Blomgren K,Hagberg H

更新日期：2000-09-11 00:00:00

abstract：OBJECTIVES:There are subclinical neurologic deficits in cirrhotic patients without overt hepatic encephalopathy. We aimed to use F-fluorodeoxyglucose PET/computed tomography to explore the impaired brain glucose metabolism of subclinical hepatic encephalopathy in cirrhosis. METHODS:Thirty-seven patients with hepatitis...

journal_title：Neuroreport

authors： Zhang W,Ning N,Li X,Li M,Duan X,Guo Y,Dang Y,Li Y,Gao J,Ye J,Yang J

更新日期：2019-08-07 00:00:00

abstract：:Plasminogen activators (PAs) have been suggested to play a role in neuronal migration and glial cell proliferation in the developing CNS. Less is known, however, about the role of PAs in the mature nervous system. To elucidate the role of tissue type plasminogen activator (tPA) in the nervous system we used in situ hy...

journal_title：Neuroreport

authors： Yuguchi T,Kohmura E,Yamada K,Otsuki H,Sakaki T,Yamashita T,Nonaka M,Sakaguchi T,Wanaka A,Hayakawa T

更新日期：1997-01-20 00:00:00

abstract：:Diffusion tensor imaging (DTI) can non-invasively examine the molecular diffusion of water in vivo and directly reflects the anatomical integrity of neural fibers in white matter. Fractional anisotropy (FA) can be calculated from DTI data, and utilized to evaluate white matter integrity. DTI was performed on 30 patien...

journal_title：Neuroreport

authors： Sun Z,Wang F,Cui L,Breeze J,Du X,Wang X,Cong Z,Zhang H,Li B,Hong N,Zhang D

更新日期：2003-10-06 00:00:00

abstract：:The cellular distribution of the rat metabotropic glutamate receptor type 4 (mGluR4) was examined in the adult rat cerebral cortex and hippocampus. Antibodies were raised against amino acid residues located in the extracellular amino terminal domain that is common to both the mGluR4a and mGluR4b splice variants, and u...

journal_title：Neuroreport

authors： Phillips T,Makoff A,Brown S,Rees S,Emson P

更新日期：1997-10-20 00:00:00

abstract：:Recently some authors have challenged the conventional association of directional motor neglect with damage of frontal structures, showing that pure sensory perceptual neglect (classically associated with parietal lesion) can follow damage of right frontal cortex. The aim of the present study was to assess the type of...

journal_title：Neuroreport

authors： Brighina F,Bisiach E,Piazza A,Oliveri M,La Bua V,Daniele O,Fierro B

更新日期：2002-12-20 00:00:00

abstract：:This study examined the effects of cocaine HCl and ambient temperature on the core body temperature of the rat. To further examine the mechanisms of cocaine-induced changes in temperature regulation, the effects of cocaine on behavioral thermoregulatory responses were also observed. At normal room temperature (20 degr...

journal_title：Neuroreport

authors： Gonzalez LP

更新日期：1993-01-01 00:00:00

abstract：:The role of the right hemisphere in recovery of language function after left hemisphere stroke remains unclear. This prospective study aimed to determine the relationship between bilateral hemispheric changes and severity of aphasia in patients with chronic left hemisphere stroke. Twenty-three patients with left hemis...

journal_title：Neuroreport

authors： Lee WM,Kyeong S,Park EY,Yang HS,Kang H,Kim DH

更新日期：2018-01-03 00:00:00

abstract：:Neuregulins (NRG), the only trophic factors known to support Schwann cell survival, have a potential for use in treatment of patients with chronic neuropathies. Expression of one NRG isoform, NRG-beta1, was increased in axons in the early phase of axonal degeneration in nerve biopsy specimens from patients with neurop...

journal_title：Neuroreport

authors： Oka N,Kawasaki T,Matsui M,Tachibana H,Sugita M,Akiguchi I

更新日期：2000-11-27 00:00:00

abstract：:We obtained visual response latencies and response durations following visual stimulation of neurones recorded in the lateral geniculate nucleus (LGN), areas 17, 18, 19, the posteromedial lateral suprasylvian sulcus (PMLS), and area 7 of the cat. We found an increasing lengthening of the mean response latencies, consi...

journal_title：Neuroreport

authors： Dinse HR,Krüger K

更新日期：1994-04-14 00:00:00

abstract：:In this study we investigated the utility of different MRI techniques for the detection and predictability of hemorrhagic transformation (HT) in a rat model of transient focal cerebral ischemia. Hemorrhagic infarction was reliably identified with gradient-echo sequences and developed between 2 and 7 days following the...

journal_title：Neuroreport

authors： Neumann-Haefelin T,Kastrup A,de Crespigny A,Ringer TM,Sun GH,Yenari MA,Moseley ME

更新日期：2001-02-12 00:00:00

abstract：:In situ hybridization and Northern blotting were used to study the expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat brain following photochemical stroke. A focal thrombotic lesion of the sensorimotor cortex was produced by intravenously injecting the light-sensitive dye rose bengal and exposing t...

journal_title：Neuroreport

authors： Comelli MC,Seren MS,Guidolin D,Manev RM,Favaron M,Rimland JM,Canella R,Negro A,Manev H

更新日期：1992-06-01 00:00:00

abstract：:Tau protein phosphorylation has been implicated as a main process that regulates microtubule dynamics. A large number of tau isoforms is generated by phosphorylation through the action of a diversity of kinases. We have analysed variations in tau phosphorylation by two-dimensional gel electrophoresis, where a great he...

journal_title：Neuroreport

authors： Araujo HM,Sutton R,Moura Neto V

更新日期：1994-10-27 00:00:00

abstract：:Rap1A, first identified as a suppressor of transformed phenotype induced by an activated ras oncogene, is abundantly expressed in the brain. Its neurophysiological function, however, is poorly understood. When an activated Rap1A mutant (Rap1-12V) or a dominant negative H-Ras mutant (Ras-17N) was expressed in CA1 neuro...

journal_title：Neuroreport

authors： Imamura Y,Matsumoto N,Kondo S,Kitayama H,Noda M

更新日期：2003-07-01 00:00:00

abstract：:Prolonged activation of brain N-methyl-D-aspartic acid (NMDA) receptors increases intraneuronal (Ca2+) and nitric oxide (NO) synthesis, and may be responsible for neuronal death in acute brain insults and chronic neurodegenerative diseases. NO can be converted in vitro to toxic hydroxyl (OH) radical. Using microdialys...

journal_title：Neuroreport

authors： Hammer B,Parker WD Jr,Bennett JP Jr

更新日期：1993-10-25 00:00:00

abstract：:Numerous reports have shown that cyclin-dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, critically contributes to the induction and maintenance of chronic pain induced by peripheral inflammation and nerve injury. Recent evidence has also suggested the critical role of an epigenetic mechanism in ...

journal_title：Neuroreport

authors： Li K,Zhao GQ,Li LY,Wu GZ,Cui SS

更新日期：2014-10-01 00:00:00

abstract：:Whereas facial emotion recognition protocols have shown that each discrete emotion has a specific time course of brain activation, there is no electrophysiological evidence to support these findings for emotional induction by complex pictures. Our objective was to specify the differences between the time courses of br...

journal_title：Neuroreport

authors： Hot P,Sequeira H

更新日期：2013-11-13 00:00:00

abstract：:Peripheral nerve injury therapy in the clinic remains less than satisfactory. The gold standard of treatment for long peripheral nerve defects is autologous nerve grafts; however, numerous clinical complications are associated with this treatment. As tissue engineering has developed, tissue-engineered nerve grafts (TE...

journal_title：Neuroreport

authors： Yan L,Yao Z,Lin T,Zhu Q,Qi J,Gu L,Fang J,Zhou X,Liu X

更新日期：2017-10-18 00:00:00

abstract：:To determine whether physical match between studied and tested items influences blood flow increases in the hippocampal formation associated with recognition memory, positron emission tomography (PET) was used to measure changes in regional cerebral blood flow while healthy volunteers made old/new judgements about lin...

journal_title：Neuroreport

authors： Schacter DL,Uecker A,Reiman E,Yun LS,Bandy D,Chen K,Cooper LA,Curran T

更新日期：1997-12-22 00:00:00

abstract：:We have previously suggested that progranulin mediates the stimulatory effects of estrogen on adult neurogenesis in the hippocampus. Neurogenesis in mature animals is enhanced by growth factors, environmental enrichment, and voluntary exercise. In this study, we investigated the role of progranulin in voluntary runnin...

journal_title：Neuroreport

authors： Asakura R,Matsuwaki T,Shim JH,Yamanouchi K,Nishihara M

更新日期：2011-12-07 00:00:00

abstract：:Pharmacological activation of group III metabotropic glutamate receptors (mGluR) or inhibition of group I mGluR by subtype-selective ligands is neuroprotective in experimental models of Parkinson's disease. The aim of this study was to investigate whether targeting both receptor subtypes simultaneously produces enhanc...

journal_title：Neuroreport

authors： Vernon AC,Croucher MJ,Dexter DT

更新日期：2008-03-05 00:00:00

abstract：:We investigated the effects of 2,2,2-trichloroethanol (TCE), the active metabolite of chloral hydrate, on large-conductance calcium-activated K+ channels (BKCa channels) of dorsal root ganglion (DRG) neurones. In outside-out patches, 2 and 5 mM TCE increased the open probability of BKCa channels to 1.7-fold and 2.8-fo...

journal_title：Neuroreport

authors： Gruss M,Hempelmann G,Scholz A

更新日期：2002-05-07 00:00:00

abstract：:The present study examined cerebral representations of Japanese long and short vowel categories with near-infrared spectroscopy (NIRS) by measuring the hemodynamic changes. Results showed that NIRS could capture phoneme-specific information. The left side of the auditory area showed large hemodynamic changes only for ...

journal_title：Neuroreport

authors： Minagawa-Kawai Y,Mori K,Furuya I,Hayashi R,Sato Y

更新日期：2002-04-16 00:00:00

abstract：:The aim of this study was to show that Cl(-)-dependent excitotoxicity, with its characteristic cell swelling, involves actual water influx into the intracellular compartment. Taking advantage of the Ca2+ omission paradigm of Cl(-)-dependent excitotoxicity, in the chick embryonic neural retina ex vivo, which is associa...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramirez G

更新日期：2000-11-27 00:00:00

abstract：:We investigated whether short-term saccadic adaptation modifies hand pointing. Subjects were presented with double-step targets, the second target jump occurring during the saccade to the first one and bringing the target back to 66% of the first target eccentricity, in order to reduce the gain of their gaze saccades....

journal_title：Neuroreport

authors： de Graaf JB,Pélisson D,Prablanc C,Goffart L

更新日期：1995-09-11 00:00:00

abstract：:In the adult rat hippocampal formation, neurogenesis occurs in the dentate gyrus subgranular zone (SGZ). We used laser capture microdissection and an antidepressant-related genes microarray to analyze gene expression profiles of cells from the SGZ and from the outermost granule cell layer. Of the differentially expres...

journal_title：Neuroreport

authors： Yamada M,Takahashi K,Ukai W,Hashimoto E,Saito T,Yamada M

更新日期：2010-01-27 00:00:00

abstract：:Skin sensory nerve nocifensor functions were investigated non-invasively in rats by measuring neurogenic inflammation and blister healing-rate after unilateral hindlimb denervation. Axon reflexes were evoked by transdermal iontophoresis of acetylcholine (ACh) or noxious electrical stimulation (TNS). Sodium nitroprussi...

journal_title：Neuroreport

authors： Carr RW,Delaney CA,Westerman RA,Roberts RG

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:Cervical spondylotic myelopathy is regarded as a chronic, special incomplete spinal cord injury, so the sensory components transmitted to thalamus decreased after distal spinal cord injury, which lead the disturbance of thalamus-cortex circuits, which might explain the alterations of clinical function of cerv...

journal_title：Neuroreport

authors： Peng X,Tan Y,He L,Ou Y

更新日期：2020-03-25 00:00:00

abstract：:The discovery of mis-sense mutations linking the presenilin-1 (PS-1) gene on chromosome 14 to Alzheimer's disease (AD) has lead to a thorough investigation of this locus. The PS-1 gene contains a polymorphism creating two alleles. The most common allele, allele 1, has been linked with late-onset AD. Given the clinical...

journal_title：Neuroreport

authors： Singleton AB,Lamb H,Leake A,McKeith IG,Ince PG,Perry RH,Morris CM

更新日期：1997-11-10 00:00:00

abstract：:Subthalamic nucleus (STN) hyperactivity follows lesions of mesencephalic dopaminergic neurons in animal models of Parkinson's disease. The mechanism leading to sustained STN hyperactivity in parkinsonism is not well understood, but it seems not to depend on the integrity of striato-pallido-subthalamic connections (the...

journal_title：Neuroreport

authors： Murer MG,Ferrario J,Delfino M,Dziewczapolski G,Gershanik OS,Raisman-Vozari R

更新日期：1999-05-14 00:00:00