Time course of brain activation elicited by basic emotions.

abstract：:Somatotopic organization of the human medial wall of the cerebral hemispheres was studied using functional MRI conducted at high field strength (3 T) with fine spatial resolution ( approximately 2 mm). Healthy subjects performed paced, repetitive movements of the fingers and toes. Within the supplementary motor area (...

journal_title：Neuroreport

authors： Mayer AR,Zimbelman JL,Watanabe Y,Rao SM

更新日期：2001-12-04 00:00:00

abstract：:The role of dopamine D1A receptors in mediating amphetamine-induced sensitization was investigated using the D1A-deficient mouse. During the drug pre-exposure phase, D1A-deficient and control mice were injected for five consecutive days with saline or amphetamine (2 mg/kg, i.p.). Locomotor activity was measured on the...

journal_title：Neuroreport

authors： Crawford CA,Drago J,Watson JB,Levine MS

更新日期：1997-07-28 00:00:00

abstract：:Diabetic peripheral neuropathy is the most common complication of diabetes mellitus and leads to sensory symptoms, including diabetic neuropathic pain (DNP). DNP is a major public health problem because it has a considerable impact on life quality of diabetes mellitus patients. Therefore, development of novel effectiv...

journal_title：Neuroreport

authors： Li P,Xiong DL,Sun WP,Xu SY

更新日期：2018-12-05 00:00:00

abstract：:Evidences in the central nervous system are in favor that adenosine under basal conditions is released by a direct excitation-secretion modality. However, till now, there is no direct evidence that adenosine is contained in synaptic vesicles. Eight synaptic vesicle fractions were recovered on a discontinuous sucrose g...

journal_title：Neuroreport

authors： Corti F,Cellai L,Melani A,Donati C,Bruni P,Pedata F

更新日期：2013-12-04 00:00:00

abstract：:Adult rats were studied for serotonin and its metabolite in basal ganglia, nociceptive responses to electric current and tremor induced by 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) to assess the effects of a single systemic injection of serotonin antiserum given at 1 day old. Antiserum-treated animals showed no over...

journal_title：Neuroreport

authors： Mohanakumar KP,Mohanty S,Ganguly DK

更新日期：1995-12-29 00:00:00

abstract：:The effect of systemic treatment with 1-aminocyclopro-panecarboxylic acid (ACPC), a partial agonist at the glycine site of the NMDA receptor, on convulsions and neurodegeneration induced by intrahippocampal injection of NMDA was investigated in mice. Five days after intrahippocampal NMDA infusion, 80-100% pyramidal ce...

journal_title：Neuroreport

authors： Zapata A,Capdevila JL,Viu E,Trullas R

更新日期：1996-01-31 00:00:00

abstract：:Epidemiological data show correlations between hypercholesterolemia and Alzheimer's disease (AD). We test the hypothesis that hypercholesterolemia modulates Abeta deposition in mice overexpressing the human APP695 Swedish mutation (K670N and M671L) (TgAPPsw). Feeding mice a high fat/high cholesterol (HFHC) diet for 7-...

journal_title：Neuroreport

authors： Shie FS,Jin LW,Cook DG,Leverenz JB,LeBoeuf RC

更新日期：2002-03-25 00:00:00

abstract：:The present study aimed to confirm and extend the finding, suggested by the results of a previous study, of different auditory neural efferent functioning in musicians compared with non-musicians. The activity of the medial olivocochlear bundle (MOCB), an auditory efferent subsystem, was measured through the contralat...

journal_title：Neuroreport

authors： Micheyl C,Khalfa S,Perrot X,Collet L

更新日期：1997-03-03 00:00:00

abstract：:Brain membrane phospholipid fatty acid composition is investigated in Alzheimer's disease using fresh pathologically proven autopsy material. The most striking abnormalities in Alzheimer brains compared to age-matched controls are found in the n - 6 line of polyunsaturated fatty acids (PUFA) showing an elevation of 18...

journal_title：Neuroreport

authors： Nakada T,Kwee IL,Ellis WG

更新日期：1990-10-01 00:00:00

abstract：:Although most neurones in the PMLS of the cat are selective for direction of motion, whether the preferred directions are organized into cortical columns, as they are in the MT area of the monkey, is not certain. We have quantitatively investigated the organization of direction selectivity of PMLS neurones. The result...

journal_title：Neuroreport

authors： Wang Y,Wang L,Li B,Wang LH,Diao YC

更新日期：1995-10-23 00:00:00

abstract：:We investigated the cardiovascular effects of bilateral microinjection of antisense oligodeoxynucleotides (oligos) into the nucleus tractus solitarii (NTS) to neuronal nitric oxide synthase (nNOS) to suppress the expression of nNOS molecular biologically. In urethane-anesthetized, paralyzed Wistar-Kyoto rats, bilatera...

journal_title：Neuroreport

authors： Maeda M,Hirano H,Kudo H,Doi Y,Higashi K,Fujimoto S

更新日期：1999-06-23 00:00:00

abstract：:An entry of Ca2+ into postsynaptic sites may play a role in the induction of long-term potentiation (LTP) of synaptic transmission in the visual cortex. To test this hypothesis, a Ca(2+)-chelator was injected into layer II/III neurons of sliced visual cortex obtained from young rats, and excitatory postsynaptic potent...

journal_title：Neuroreport

authors： Kimura F,Tsumoto T,Nishigori A,Yoshimura Y

更新日期：1990-09-01 00:00:00

abstract：:Motor fluctuations that ultimately complicate the response of most parkinsonian patients to levodopa therapy might represent a form of behavioral or neuronal plasticity. Since various forms of neuronal plasticity appear to be mediated by glutamate transmission through the N-methyl-D-aspartate (NMDA) receptor, the effe...

journal_title：Neuroreport

authors： Engber TM,Papa SM,Boldry RC,Chase TN

更新日期：1994-12-20 00:00:00

abstract：:There is no unifying hypothesis to account for the anatomical distribution of neuropathology, the involvement of beta-amyloid precursor protein (beta APP) and the role of increasing age in triggering the Alzheimer disease process. We report here that layer II pre-alpha neurones in transentorhinal and entorhinal cortex...

journal_title：Neuroreport

authors： Roberts GW,Nash M,Ince PG,Royston MC,Gentleman SM

更新日期：1993-01-01 00:00:00

abstract：:A number of epidemiological studies suggest that estrogen therapy is linked to a reduced risk of developing Alzheimer's disease (AD). The present study was conducted to evaluate the effect of 17beta-estradiol on beta-amyloid (Abeta)-induced toxicity and was performed in rat pheochromocytoma PC 12 cells by measuring th...

journal_title：Neuroreport

authors： Svensson AL,Nordberg A

更新日期：1999-11-26 00:00:00

abstract：:The hypothesis that sleep participates in the consolidation of recent memory traces has been investigated using four main paradigms: (1) effects of post-training sleep deprivation on memory consolidation, (2) effects of learning on post-training sleep, (3) effects of within sleep stimulation on the sleep pattern and o...

journal_title：Neuroreport

authors： Peigneux P,Laureys S,Delbeuck X,Maquet P

更新日期：2001-12-21 00:00:00

abstract：:Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg mo...

journal_title：Neuroreport

authors： Sharpe LG,Jaffe JH

更新日期：1990-09-01 00:00:00

abstract：:The in-vivo extracellular release of acetylcholine (ACh) from the striatum of rats was measured by intracerebral microdialysis. The ACh levels were first estimated under normoxic conditions, after which the rats were exposed to either 10% or 5% oxygen for 1 h. The average ACh content was 2.9 pmol/20 min. During hypoxi...

journal_title：Neuroreport

authors： Chleide E,Ishikawa K

更新日期：1990-11-01 00:00:00

abstract：:We used positron emission tomography to investigate whether tactile motion discrimination activates the dorsal visual stream in congenitally blind (CB) participants compared with sighted controls. The tactile stimuli consisted of either static dots, dots moving coherently in one of two possible directions, or in rando...

journal_title：Neuroreport

authors： Ptito M,Matteau I,Gjedde A,Kupers R

更新日期：2009-04-22 00:00:00

abstract：:In situ hybridization has demonstrated mRNA for olfactory receptors (OR) in the axon terminals of olfactory receptor neurons. Neurons that express the same OR appear to send their axons to two stereotyped glomeruli in the olfactory bulb (OB). Based on these observations, we tested the feasibility of using RT-PCR to is...

journal_title：Neuroreport

authors： Singer MS,Hughes TE,Shepherd GM,Greer CA

更新日期：1998-11-16 00:00:00

abstract：:Since the first identification of an association between mutations in the connexin26 (Cx26) gene and autosomal recessive non-syndromic deafness it has been shown that several mutations in this gene cause recessive, sporadic, and dominant non-syndromic deafness. Three novel mutations in the Cx26 gene were identified in...

journal_title：Neuroreport

authors： Fuse Y,Doi K,Hasegawa T,Sugii A,Hibino H,Kubo T

更新日期：1999-06-23 00:00:00

abstract：:In contrast to mechanisms mediating synaptic plasticity, the pharmacological basis of perceptual learning remains to be clarified. Here we report that a specific form of perceptual learning is influenced by GABAergic mechanisms. We induced perceptual learning by Hebbian co-activation of the skin of the tip of the righ...

journal_title：Neuroreport

authors： Dinse HR,Ragert P,Pleger B,Schwenkreis P,Tegenthoff M

更新日期：2003-09-15 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:The aim of this study was to identify differences in structural and functional brain connectivity between poststroke mild and severe motor impairment. Twenty-four chronic stroke patients who underwent resting-state functional MRI and diffusion tensor image were retrospectively included. All patients were classified in...

journal_title：Neuroreport

authors： Lee JH,Kyeong S,Kang H,Kim DH

更新日期：2019-05-01 00:00:00

abstract：:We investigated the effects of radio frequency electromagnetic fields on brain physiology. Twenty-four healthy young men were exposed for 30 min to pulse-modulated or continuous-wave radio frequency electromagnetic fields (900 MHz; peak specific absorption rate 1 W/kg), or sham exposed. During exposure, participants p...

journal_title：Neuroreport

authors： Regel SJ,Gottselig JM,Schuderer J,Tinguely G,Rétey JV,Kuster N,Landolt HP,Achermann P

更新日期：2007-05-28 00:00:00

abstract：:Using NADPH-diaphorase (NADPH-d) histochemistry, the expression of nitric oxide synthase (NOS) was studied in the rat brain 1 week after kainate-induced status epilepticus. Major changes were observed in the hippocampi of epileptic animals, especially a loss of NADPH-d positive fibres in the periphery of degenerative ...

journal_title：Neuroreport

authors： Lerner-Natoli M,de Bock F,Bockaert J,Rondouin G

更新日期：1994-12-20 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy was used to determine effects of acute and chronic alcohol exposure on brain intracellular free magnesium concentration (Mgf) and bioenergetic state in rats. Acute alcohol (3 mg kg-1, i.p.) resulted in a transient ( < 2h) decline in brain Mgf and cytosolic phosphorylation rat...

journal_title：Neuroreport

authors： Mullins PG,Vink R

更新日期：1995-08-21 00:00:00

abstract：:Sulphated cholecystokinin-8 (CCK-8) given into the neostriatum of the rat by in vivo microdialysis produced a concentration-dependent (1-100 microM) increase in extracellular aspartate (Asp) and dynorphin B (Dyn B), but not in glutamate, GABA or dopamine levels. The increase in Asp levels produced by 10 microM CCK-8 w...

journal_title：Neuroreport

authors： You ZB,Pettersson E,Herrera-Marschitz M,Hökfelt T,Terenius L,Nylander I,Goiny M,Hughes J,O'Connor WT,Ungerstedt U

更新日期：1994-11-21 00:00:00

abstract：:The presence and regulation of pituitary adenylate cyclase activating peptide (PACAP) was investigated in the adult rat superior cervical ganglion. Double-labelling immunofluorescence using specific antibodies against PACAP and vasoactive intestinal peptide (VIP) revealed a dense innervation of postganglionic sympathe...

journal_title：Neuroreport

authors： Klimaschewski L,Hauser C,Heym C

更新日期：1996-11-04 00:00:00

abstract：:Internet gaming disorder is defined as excessive and compulsive use of the internet to engage in games that leads to clinically significant psychosocial impairment. We tested the hypothesis that individuals with internet gaming disorder would be less sensitive to high-risk situations and show aberrant brain activation...

journal_title：Neuroreport

authors： Lee D,Lee J,Yoon KJ,Kee N,Jung YC

更新日期：2016-05-25 00:00:00