Abstract:
:Somatotopic organization of the human medial wall of the cerebral hemispheres was studied using functional MRI conducted at high field strength (3 T) with fine spatial resolution ( approximately 2 mm). Healthy subjects performed paced, repetitive movements of the fingers and toes. Within the supplementary motor area (SMA), two regions were identified: finger movements activated a region rostral and superior to that for toe movements. Two activation foci were also identified in the cingulate motor area: toe movements activated a region rostral and ventral to that activated by finger movements. All foci were located between the anterior and posterior commissures. Our results confirm previous human and non-human primate studies regarding the rostral-caudal organization of the SMA and CMA. The dorsal-ventral organization of the CMA, however, appears to be divergent from results derived from cortical stimulation studies conducted in non-human primates.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Mayer AR,Zimbelman JL,Watanabe Y,Rao SMdoi
10.1097/00001756-200112040-00042subject
Has Abstractpub_date
2001-12-04 00:00:00pages
3811-4issue
17eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::We have previously suggested that progranulin mediates the stimulatory effects of estrogen on adult neurogenesis in the hippocampus. Neurogenesis in mature animals is enhanced by growth factors, environmental enrichment, and voluntary exercise. In this study, we investigated the role of progranulin in voluntary runnin...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32834bf4ca
更新日期:2011-12-07 00:00:00
abstract::The regulation of glucocorticoid receptors and nuclear factor kappaB was evaluated in the spiral ganglion neurons after 4 h of restraint stress in the mouse cochlea. Immediately after restraint stress, glucocorticoid receptor protein expression was not altered in spiral ganglion neurons even though both the plasma cor...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000220131.24468.e7
更新日期:2006-06-26 00:00:00
abstract::To compare the maximum Hoffmann reflex (H-reflex) and the maximum M-wave (H : M) ratio of the H-reflex in men and women when all participants showed similar saliva levels of estradiol and progesterone. This is a cohort design study involving healthy men and women with a mean age of 22.4±3.4 years. The H : M ratio of t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000961
更新日期:2018-03-07 00:00:00
abstract::Glial cell line-derived neurotrophic factor (GDNF) exhibits neurotrophic properties on different types of neurones, including fetal motoneurones and embryonic neurones of sensory ganglia. We demonstrate that chronic injury to the adult rat sciatic nerve induces a rapid up-regulation of GDNF mRNA expression in Schwann ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199603220-00004
更新日期:1996-03-22 00:00:00
abstract::In order to ascertain whether disturbances of neurogenesis occur in chronic neurodegenerative disorders, we assessed hippocampal cell proliferation in the R6/1 transgenic mouse model of Huntington's disease (HD). Using BrdU labelling for dividing cells at two different time points (5 and 20 weeks) in transgenic and wi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200404090-00014
更新日期:2004-04-09 00:00:00
abstract::The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199604100-00010
更新日期:1996-04-10 00:00:00
abstract::Modulation of the soleus H-reflex following galvanic vestibular stimulation (GVS) has been used to evaluate vestibulospinal tract function. It is not known whether this modulation is because of vestibular stimulation and/or cutaneous stimulation, and the suitable stimulating intensity of GVS for the modulation is not ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001086
更新日期:2018-09-05 00:00:00
abstract::The immediate-early genes, especially c-fos, have been suggested to have an important role in neuronal plasticity and memory. However, it has been difficult to determine if in fact c-fos can participate in control of behaviour. Here we can report that direct unilateral infusion into the rat neostriatum of an antisense...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199312000-00024
更新日期:1993-12-13 00:00:00
abstract::We investigated the effects of radio frequency electromagnetic fields on brain physiology. Twenty-four healthy young men were exposed for 30 min to pulse-modulated or continuous-wave radio frequency electromagnetic fields (900 MHz; peak specific absorption rate 1 W/kg), or sham exposed. During exposure, participants p...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/WNR.0b013e3280d9435e
更新日期:2007-05-28 00:00:00
abstract::Using a system capable of relatively localized and rapidrate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199601310-00035
更新日期:1996-01-31 00:00:00
abstract::Presenilin-1 (PS-1) and amyloid precursor protein (APP) have been linked to the pathogenesis of Alzheimer's disease. While APP accumulation is well documented in several models of brain injury, the role of PS-1 levels in neurodegeneration, if any, remains to be elucidated. The current studies examined PS-1 and APP exp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199707280-00041
更新日期:1997-07-28 00:00:00
abstract::The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-200011270-00047
更新日期:2000-11-27 00:00:00
abstract::Müller cells, as the predominant glial element in the sensory retina, play a crucial role in healthy and diseased retina. Overactivation of Müller cells in response to damage is detrimental to the retina tissue. Current research shows that inhibiting glial fibrillary acidic protein (GFAP), a sensitive indicator of Mül...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001143
更新日期:2018-12-05 00:00:00
abstract::Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-deliv...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833776a3
更新日期:2010-03-31 00:00:00
abstract::Dopaminergic neurotransmission is thought to be involved in reward-related incentive learning and addictive behaviour. Amphetamine will alter glycogen synthase kinase-3β (GSK-3β) activity by increasing dopamine transporter efflux rates. We investigated the hypothesis that Wnt signalling will be altered in rat nucleus ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328357d868
更新日期:2012-10-03 00:00:00
abstract::Hypoxic-ischemic represents a common cause of damage to the prenatal brain and can co-occur with prematurity. Prematurity is associated with emergent language impairments, and it has been suggested that rapid auditory processing deficits play a causal role in language difficulties. We previously demonstrated rapid aud...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175613.16183.6c
更新日期:2005-08-22 00:00:00
abstract::Changes of serum immunoglobulin (Ig) concentrations may occur in both brain tumours and lumbar disc diseases (LDD). The purpose of this study was to investigate the changes of pre- and post-operative serum Ig levels in brain tumours and LDDs. Serum IgG, IgA and IgM levels were measured in 127 patients with brain tumou...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-200002070-00011
更新日期:2000-02-07 00:00:00
abstract::Recently, it has been shown that visual perception can be radically altered by signals of other modalities. For example, when a single flash is accompanied by multiple auditory beeps, it is often perceived as multiple flashes. This effect is known as the sound-induced flash illusion. In order to investigate the princi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000187634.68504.bb
更新日期:2005-11-28 00:00:00
abstract::Axons from central neurons can regenerate into the tissue matrix formed within a silicone tube capped with two pieces of peripheral nerve, one of which had been sutured to a lesion in the spinal cord. Such axons can grow through a transversely positioned microchip in the tube. These observations suggest that it is fea...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199803300-00018
更新日期:1998-03-30 00:00:00
abstract::Alzheimer disease (AD) patients show increased plasma levels of homocysteine, whose conversion to methionine is catalyzed by methionine synthase (MS). Although altered MS activity may result from the MS A2756G polymorphism, the latter's possible associ-ation with AD remains unexplored. To assess whether the MS A2756G ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000073683.00308.0e
更新日期:2003-07-18 00:00:00
abstract::The putative neurotransmitter peptide CART has been suggested to be involved in the actions of psychostimulants. We analyzed the CART mRNA expression in mesolimbic brain areas of male and ovariectomized 17beta-estradiol- (30 microg) and vehicle-treated female rats. A gender difference was noted in the accumbens shell ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199911080-00034
更新日期:1999-11-08 00:00:00
abstract::We studied the effects of the non-NMDA antagonist NBQX and of the NMDA antagonist dizocilpine (MK-801), administered separately or together, on the respiratory function of conscious cats. NBQX (20 mg kg-1) did not affect minute ventilation nor the timing of inspiratory and expiratory phases, but the addition of a smal...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199401120-00028
更新日期:1994-01-12 00:00:00
abstract::In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199907130-00028
更新日期:1999-07-13 00:00:00
abstract::The auditory-evoked potential's N1 component of the scalp electroencephalogram is a well-established measure of electrical brain activity. The N1 reflects basic auditory processing and is modulated by auditory experience, for instance, by musical training. Here, we explore a possible correlation between the auditory N...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32835abc5c
更新日期:2012-12-05 00:00:00
abstract::A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199703240-00035
更新日期:1997-03-24 00:00:00
abstract::To compare the effectiveness of cyclosporin-A (CsA) with methylprednisolone (MP) or a combination of both upon inhibition of lipid peroxidation (LP) after spinal cord (SC) injury, rats were treated with either CsA, MP, CSA+MP or vehicle starting 1 h after SC contusion at T9 level. LP was assessed 24h after injury by t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200006050-00033
更新日期:2000-06-05 00:00:00
abstract::The primate pulvinar connects with the entire array of known visual areas and is postulated to play a role in selective visual attention. Recently, five separate neurochemical subdivisions of a region termed the inferior pulvinar (PI) complex were identified in monkeys. In the present study, similar histochemical proc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199912160-00002
更新日期:1999-12-16 00:00:00
abstract::Recent studies have discussed the role of the cerebellum in not only motor but also cognitive functions, and in particular, fronto-executive operations. Similar to a previous study on hemineglect patients, we recorded eye movements during a visual search task to investigate patients with isolated infarction of the cer...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000177015.75096.b6
更新日期:2005-09-08 00:00:00
abstract::EphA5 and its ligand ephrin-A5 interaction can trigger synaptogenesis during early hippocampus development. We have previously reported that abnormal EphA5 expression can result in synaptogenesis disorder in congenital hypothyroidism (CH) rats. To better understand its precise molecular mechanism, we further analyzed ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001047
更新日期:2018-08-01 00:00:00
abstract::The environment in which cocaine is experienced becomes associated with the effects of the drug and can then elicit cocaine craving. This study examined whether the hippocampus is involved in such associations using the conditioned place preference model. Rats received bilateral lesions of the dorsal or ventral hippoc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200311140-00023
更新日期:2003-11-14 00:00:00