NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C.

abstract：:The present study was based on earlier findings that the observation of a coherently moving long bar induced gamma-band activity in humans. The power in the EEG-gamma-band was reduced during the presentation of two incoherently moving short bars. The present study demonstrates the replicability of this cortical activi...

journal_title：Neuroreport

authors： Müller MM,Junghöfer M,Elbert T,Rochstroh B

更新日期：1997-07-28 00:00:00

abstract：:It is often claimed that binding information across sensory modalities leads to coherent, unitary mental representations. The dramatic illusions experienced as a result of intersensory conflict, such as the McGurk effect, are often attributed to a propensity of the perceptual system to impose multisensory coherence on...

journal_title：Neuroreport

authors： Soto-Faraco S,Alsius A

更新日期：2007-03-05 00:00:00

abstract：:Matrix metalloproteinases (MMPs) may contribute to tissue damage after cerebral ischemia. In this study, wildtype and MMP-2 knockout mice were subjected to permanent and transient (2 h) occlusions of the middle cerebral artery. Gelatin zymography showed that MMP-9 levels were increased in all brains after ischemia. MM...

journal_title：Neuroreport

authors： Asahi M,Sumii T,Fini ME,Itohara S,Lo EH

更新日期：2001-09-17 00:00:00

abstract：:Amyloid plaques and neurofibrillary tangles are the major pathological hallmarks of Alzheimer's disease. Neurofibrillary tangles are composed of filaments and paired helical filaments containing polymerized hyperphosphorylated tau protein. Derlin proteins are a family of proteins that are conserved in all eukaryotes, ...

journal_title：Neuroreport

authors： Honjo Y,Ito H,Horibe T,Shimada H,Nakanishi A,Mori H,Takahashi R,Kawakami K

更新日期：2012-07-11 00:00:00

abstract：:We reported differential expression of the transient receptor potential vanilloid 1 (TRPV1), the transient receptor potential ankyrin 1 (TRPA1), and the (TRPM8) in the geniculate ganglions (GGs) of naive rats. In medical practice, the chorda tympani nerve (CTN) is injured in some patients during middle-ear surgery, an...

journal_title：Neuroreport

authors： Tatsumi E,Katsura H,Kobayashi K,Yamanaka H,Tsuzuki K,Noguchi K,Sakagami M

更新日期：2015-09-30 00:00:00

abstract：:The phonemic structure of the maternal language determines the way of perceiving speech signals. A typical example is that native Japanese listeners map two English phonemes, /r/ and /l/, onto the same /R/. This perceptual assimilation of speech sounds has been associated with the left and/or right posterior perisylvi...

journal_title：Neuroreport

authors： Hara NF,Nakamura K,Kuroki C,Takayama Y,Ogawa S

更新日期：2007-10-08 00:00:00

abstract：:Hyperactivity of the hypothalamic-pituitary-adrenal axis and impairment of the central corticotropin-releasing factor system are factors in the pathogenesis of depression. Though several antagonists of the corticotropin-releasing factor 1 receptor were effective in the recognized behavioral tests for antidepressant ac...

journal_title：Neuroreport

authors： Wang XB,Zhang YQ,Xue RR,Yang ZZ,Zhang XF

更新日期：2020-01-08 00:00:00

abstract：:Impaired print tuning in dyslexia has been shown in alphabetic languages; whether we can observe the same in a nonalphabetic language such as Chinese is still questionable. The present study investigated the N170 component in response to Chinese words versus nonword pseudo-words in 10-year-old children with developmen...

journal_title：Neuroreport

authors： Zhou L,Yan X

更新日期：2018-10-17 00:00:00

abstract：:We compared beta-amyloid peptide (Abeta) levels in the serum, CSF and brain (hippocampus) and correlated these with spatial learning in APP+PS1 transgenic mice. Compared with non-transgenic littermates, male 14-month-old APP + PS1 mice were impaired in spatial learning in the water maze. Among the APP + PS1 mice, only...

journal_title：Neuroreport

authors： Liu L,Tapiola T,Herukka SK,Heikkilä M,Tanila H

更新日期：2003-01-20 00:00:00

abstract：:AMPA (EC50 = 1.0 x 10(-6) M) and NMDA (EC50 = 1.3 x 10(-4) M) trigger 45Ca2+ influx in 13-day chick embryonic retinal explants. This agonist-driven cationic flux is specifically inhibited by typical competitive antagonists, such as 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 2-amino-7-phosphonoheptanoate (AP7), respec...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramírez G

更新日期：2000-07-14 00:00:00

abstract：:This study aimed to examine the spontaneous hemodynamic fluctuations and the dysfunctional brain regions in patients with generalized anxiety disorder (GAD) using resting-state functional MRI. Previous studies have demonstrated some neural networks that are different in this patient group compared with healthy control...

journal_title：Neuroreport

authors： Li C,Su S,Wu H,Zhu Y

更新日期：2018-03-21 00:00:00

abstract：:As early-onset hypothyroidism produces audiogenic seizure susceptibility (AGS) in rodents, the role of TR alpha 1 and TR beta thyroid hormone receptors in AGS was investigated. AGS occurs in mice lacking specifically TR beta (Thrb(tm1/tm1)) and is marked by early onset and persistence, thereby differing from mouse str...

journal_title：Neuroreport

authors： Ng L,Pedraza PE,Faris JS,Vennström B,Curran T,Morreale de Escobar G,Forrest D

更新日期：2001-08-08 00:00:00

abstract：:This study tested the hypothesis that inhibition of nitric oxide synthase (NOS) in the medial pontine reticular formation (mPRF) would cause decreased acetylcholine (ACh) release. Microdialysis of cat mPRF permitted measurement of ACh during states of wakefulness, non-rapid eye movement (NREM) sleep and rapid eye move...

journal_title：Neuroreport

authors： Leonard TO,Lydic R

更新日期：1995-07-31 00:00:00

abstract：:The H-Tx rat is a polygenic inherited model of hydrocephalus. In order to identify disease-specific biomarkers associated with congenital hydrocephalus, comparative proteomic analysis was used to screen cerebellum proteins in H-Tx rats at 1 day after birth. Seven proteins showed significant changes in hydrocephalic H-...

journal_title：Neuroreport

authors： Li X,Miyajima M,Mineki R,Taka H,Murayama K,Arai H

更新日期：2005-04-25 00:00:00

abstract：:Bone marrow mononuclear cells (BMMCs) are known to enhance recovery from ischemic insults by secreting angiogenic factors and inducing the expression of angiogenic factors from host tissues. Therefore, the transplantation of BMMCs is considered a potential approach to promoting the repair of ischemic damaged organs. H...

journal_title：Neuroreport

authors： Takagi T,Yoshida T,Okada M,Hata R,Hato N,Gyo K,Hakuba N

更新日期：2014-08-06 00:00:00

abstract：:Little is known regarding opioid receptors in the human cerebellum. The present [11C]diprenorphine PET study investigated opioid receptor binding in the human cerebellum in vivo, and showed a differential binding level in cerebellar cortex, vermis and dentate nuclei. The additional study in vitro of opioid receptors i...

journal_title：Neuroreport

authors： Schadrack J,Willoch F,Platzer S,Bartenstein P,Mahal B,Dworzak D,Wester HJ,Zieglgänsberger W,Tölle TR

更新日期：1999-02-25 00:00:00

abstract：:The effect of temporal interference of physiological signals on time-lag effective connectivity, derived from a functional network connectivity tool box (FNC), was examined by a blood-oxygen-level-dependent functional MRI study of action. The known effect of physiological signals on time-lag FNC was verified by (a) co...

journal_title：Neuroreport

authors： Huang JM,Cheng CM,Chou CC,Chen YC,Hsu PY,Yeh TC

更新日期：2013-01-09 00:00:00

abstract：:Nerve damage often leads to nervous system dysfunction and neuropathic pain. The serine-threonine kinases receptor-interacting protein 1 (RIP1) and 3 (RIP3) are associated with inflammation and cell necrosis. This study aimed to explore the role of RIP1 and RIP3 in sciatic nerve chronic constriction injury (CCI) in mi...

journal_title：Neuroreport

authors： Pu S,Li S,Xu Y,Wu J,Lv Y,Du D

更新日期：2018-11-07 00:00:00

abstract：:Chimeric mice stably reconstituted with bone marrow cells represent a good model for analysis of the mechanism of bone marrow cell infiltration in the brain. However, in preparing chimeric mice, irradiation of the recipient mice is necessary to kill their own bone marrow before transplantation, which induces gliosis a...

journal_title：Neuroreport

authors： Furuya T,Tanaka R,Urabe T,Hayakawa J,Migita M,Shimada T,Mizuno Y,Mochizuki H

更新日期：2003-03-24 00:00:00

abstract：:It has been reported that intracerebroventricular (i.c.v.) injection of nociception/orphanin FQ (OFQ) can antagonize morphine analgesia, whereas i.c.v. OFQ antibody can reverse morphine tolerance. Nocistatin (NST) is a recently characterized neuropeptide possessing an antagonizing effect on OFQ. Here we examine whethe...

journal_title：Neuroreport

authors： Sun RQ,Zhao CS,Wang HJ,Jing Z,Wang W,Yang K,Wang Y,Chang JK,Han JS

更新日期：2001-06-13 00:00:00

abstract：:We investigated the effects of 2,2,2-trichloroethanol (TCE), the active metabolite of chloral hydrate, on large-conductance calcium-activated K+ channels (BKCa channels) of dorsal root ganglion (DRG) neurones. In outside-out patches, 2 and 5 mM TCE increased the open probability of BKCa channels to 1.7-fold and 2.8-fo...

journal_title：Neuroreport

authors： Gruss M,Hempelmann G,Scholz A

更新日期：2002-05-07 00:00:00

abstract：:In this study, we examined the expression of insulin-like growth factor I (IGF-I) and its receptor (IGF-IR) in dorsal root ganglia (DRG) neurons in two rodent models of nerve injury: sciatic nerve axotomy and streptozotocin-induced (STZ) painful diabetic neuropathy. We demonstrate that IGF-I and its receptor are prefe...

journal_title：Neuroreport

authors： Craner MJ,Klein JP,Black JA,Waxman SG

更新日期：2002-09-16 00:00:00

abstract：:We investigated the effect of the muscarinic acetylcholine receptor (mAChR) antagonist scopolamine on eyeblink conditioning in glutamate receptor subunit 62 null mice, which have severe impairments in cerebellar long-term depression (LTD). Mice were injected intraperitoneally with scopolamine (0.5 mg/kg) or saline, an...

journal_title：Neuroreport

authors： Takatsuki K,Kawahara S,Mori H,Mishina M,Kirino Y

更新日期：2002-01-21 00:00:00

abstract：:Inhibitory deficits are one of the predominant causes of cognitive aging. This study examined age-related changes in response inhibition. In this study, young and older participants performed a bimanual/bipedal response inhibition task while we measured their brain activity via functional near-infrared spectroscopy. P...

journal_title：Neuroreport

authors： Kawai N,Nakata R,Kubo-Kawai N

更新日期：2020-10-07 00:00:00

abstract：:To study the penetration of magnesium ions from blood into brain tissue, magnesium content in serum and hippocampus of normal and of excitotoxically affected rats was estimated after a single subcutaneous injection of magnesium sulphate (600 mg kg-1). In normal rats Mg2+ levels in serum rose from 1 to 6 mM, while that...

journal_title：Neuroreport

authors： Rothe F,Wolf G,Fischer S,Hass P,Keilhoff G,Abicht K

更新日期：1993-02-01 00:00:00

abstract：:High homocysteine serum level has been regarded as one of the important factors that influence the development of schizophrenia. Genetic variations of methylenetetrahydrofolate reductase, which is a main enzyme reducing homocysteine level, are reported in schizophrenic patients. We measured the serum level of homocyst...

journal_title：Neuroreport

authors： Lee YS,Han DH,Jeon CM,Lyoo IK,Na C,Chae SL,Cho SC

更新日期：2006-05-15 00:00:00

abstract：:Event-related potential studies have reported error-related negativity following both error commission and feedback indicating errors or monetary loss. The present study examined whether error-related negativities could be elicited by a predictive cue presented prior to both the decision and subsequent feedback in a g...

journal_title：Neuroreport

authors： Dunning JP,Hajcak G

更新日期：2007-11-19 00:00:00

abstract：:Peripheral nerve injury therapy in the clinic remains less than satisfactory. The gold standard of treatment for long peripheral nerve defects is autologous nerve grafts; however, numerous clinical complications are associated with this treatment. As tissue engineering has developed, tissue-engineered nerve grafts (TE...

journal_title：Neuroreport

authors： Yan L,Yao Z,Lin T,Zhu Q,Qi J,Gu L,Fang J,Zhou X,Liu X

更新日期：2017-10-18 00:00:00

abstract：:The present study examines whether or not prolactin-releasing peptide (PrRP) infused intracerebroventricularly (i.c.v.) affects sleep and the release of prolactin (PRL) and growth hormone (GH) in rats. At a dose of 0.1 nmol, PrRP promoted rapid-eye-movement (REM) sleep, whereas 1.0 nmol increased both non-REM and REM ...

journal_title：Neuroreport

authors： Zhang SQ,Inoué S,Kimura M

更新日期：2001-10-29 00:00:00

abstract：:Cells overexpressing the beta-amyloid precursor protein possessing a mutation found in familial Alzheimer's disease overproduce beta-amyloid peptide (A beta). Because these findings were based on immunological identification, we have chemically characterized the peptides produced. Purified A beta fragments from the co...

journal_title：Neuroreport

authors： Dovey HF,Suomensaari-Chrysler S,Lieberburg I,Sinha S,Keim PS

更新日期：1993-08-01 00:00:00